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    Quinazoline derivatives
    21.
    发明授权
    Quinazoline derivatives 失效
    喹唑啉衍生物

    公开(公告)号：US06399602B1

    公开(公告)日：2002-06-04

    申请号：US09152070

    申请日：1998-09-11

    Applicant: Andrew John Barker ,  Craig Johnstone

    Inventor： Andrew John Barker ,  Craig Johnstone

    IPC: C07D40100

    CPC classification number: C07D231/12 ,  C07D233/56 ,  C07D239/94 ,  C07D249/08 ,  C07D401/04 ,  C07D401/12 ,  C07D403/04 ,  C07D403/12 ,  C07D405/04 ,  C07D405/12 ,  C07D409/04 ,  C07D409/12 ,  C07D413/04 ,  C07D413/12 ,  C07D413/14

    Abstract: The invention concerns quinazoline derivatives of the formula I wherein X1 is a direct link or a group such as CO, C(R2)2 and CH(OR2); wherein Q1 is phenyl, naphthyl or a 5- or 6-membered heteroaryl moiety and Q1 optionally bears up to 3 substituents; wherein m is 1 or 2 and each R1 may be a group such as hydrogen, halogeno and trifluoromethyl; and wherein Q2 may be phenyl or a 9- or 10-membered bicyclic heterocyclic moiety and Q2 optionally bears up to 3 substituents; or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and the use of their receptor tyrosine kinase inhibitory properties in the treatment of proliferative disease such as cancer.

    Abstract translation: 本发明涉及式I的喹唑啉衍生物，其中X1是直接键或诸如CO，C（R 2）2和CH（OR 2）的基团;其中Q 1是苯基，萘基或5-或6-元杂芳基部分和Q 1 任选地带有至多3个取代基;其中m是1或2，并且每个R 1可以是诸如氢，卤代和三氟甲基的基团; 并且其中Q2可以是苯基或9或10元双环杂环部分，Q2任选地带有至多3个取代基;或其药学上可接受的盐;其制备方法，含有它们的药物组合物及其受体酪氨酸激酶 治疗增殖性疾病如癌症的抑制性质。

    Quinazoline derivative
    22.
    发明授权
    Quinazoline derivative 失效
    喹唑啉衍生物

    公开(公告)号：US5952333A

    公开(公告)日：1999-09-14

    申请号：US930044

    申请日：1997-09-26

    Applicant: Andrew John Barker

    Inventor： Andrew John Barker

    IPC: A61K31/505 ,  A61K31/517 ,  A61P35/00 ,  A61P43/00 ,  C07D239/94

    CPC classification number: C07D239/94

    Abstract: The invention concerns the quinazoline derivative 6-(2-methoxyethylamino)-7-methoxy-4-(3'-methylanilino)quinazoline, or a pharmaceutically-acceptable salt thereof, processes for its preparation, pharmaceutical compositions containing the compound and the use of the receptor tyrosine kinase inhibitory properties of the compound in the treatments of proliferative disease such as cancer.

    Abstract translation: PCT No.PCT / GB96 / 00962 Sec。 371日期：1997年9月26日 102（e）1997年9月26日PCT PCT 1996年4月23日PCT公布。 公开号WO96 / 33981 日期1996年10月31日本发明涉及喹唑啉衍生物6-（2-甲氧基乙氨基）-7-甲氧基-4-（3'-甲基苯胺基）喹唑啉或其药学上可接受的盐，其制备方法， 化合物和使用化合物在增殖性疾病如癌症治疗中的受体酪氨酸激酶抑制性质。

    Resuscitation mask
    24.
    发明授权
    Resuscitation mask 失效
    恢复面具

    公开(公告)号：US3626936A

    公开(公告)日：1971-12-14

    申请号：US3626936D

    申请日：1969-10-27

    Applicant: DANIEL GEORGE JOHN BARKER

    Inventor： BARKER DANIEL GEORGE JOHN

    IPC: A61M16/00

    CPC classification number: A61M16/0048 ,  Y10T137/7783

    Abstract: A resuscitation device comprising a masking sheet to lay over the mouth of the patient, an opening in the sheet and a valve device attached to the sheet to permit air to be blown through the opening into the patient''s mouth, said opening being closed by the valve device by exhalation from the patient.

    Connector for use with top drive system
    27.
    发明授权
    Connector for use with top drive system 有权
    用于顶级驱动系统的连接器

    公开(公告)号：US08733434B2

    公开(公告)日：2014-05-27

    申请号：US13214949

    申请日：2011-08-22

    Applicant: Stewart John Barker

    Inventor： Stewart John Barker

    IPC: E21B19/06

    CPC classification number: E21B17/00 ,  E21B3/02 ,  E21B19/16

    Abstract: In some embodiments, apparatus connectable between a top drive system and a tool useful in connection with a hydrocarbon exploration or production well includes a rotatable barrel, a non-rotating upper housing engageable with the top drive system, a rotatable lower housing engageable with the tool and a non-rotating communication ring.

    Abstract translation: 在一些实施例中，可在顶部驱动系统和与碳氢化合物勘探或生产井有关的工具之间连接的设备包括可旋转筒体，可与顶部驱动系统接合的不旋转上部壳体，可与工具接合的可旋转下部壳体 和非旋转通信环。

    Catheter insertion device with retractable needle
    28.
    发明授权
    Catheter insertion device with retractable needle 有权
    导管插入装置带有伸缩针

    公开(公告)号：US07524306B2

    公开(公告)日：2009-04-28

    申请号：US10727363

    申请日：2003-12-03

    Applicant: Michael J. Botich ,  Thor R. Halseth ,  John Barker

    Inventor： Michael J. Botich ,  Thor R. Halseth ,  John Barker

    IPC: A61M5/178

    CPC classification number: A61M25/0631 ,  A61M5/3232 ,  A61M25/0693 ,  A61M2025/006

    Abstract: A catheter insertion device is provided for inserting an over-the-needle catheter. The device includes an insertion needle that is retractable into the housing of the device after use to prevent exposure to the contaminated needle. A needle retainer releasably retains the needle in an extended position against the rearward bias of the biasing element. The needle retainer engages the hub of the catheter so that when the catheter is removed from the insertion device, the needle retainer automatically releases the needle. The biasing element then propels the needle rearwardly into the housing of the device. The device further allows the operator to intervene to delay retraction if desired.

    Abstract translation: 提供导管插入装置用于插入针管上的导管。 该装置包括插入针，该插入针在使用后可伸缩到装置的壳体中，以防止暴露于受污染的针。 针保持器可释放地将针保持在抵抗偏置元件的向后偏置的延伸位置。 针保持器接合导管的毂，使得当导管从插入装置移除时，针保持器自动释放针。 然后，偏置元件将针推向装置的壳体中。 如果需要，该装置还允许操作者介入以延迟缩回。

    Magnetic-based releasable, adjustable camera or other device mount apparatus
    30.
    发明申请
    Magnetic-based releasable, adjustable camera or other device mount apparatus 审中-公开
    磁性可释放，可调节相机或其他装置安装装置

    公开(公告)号：US20080023607A1

    公开(公告)日：2008-01-31

    申请号：US11904790

    申请日：2007-09-28

    Applicant: John Barker

    Inventor： John Barker

    IPC: A47F5/00 ,  G03B17/00 ,  H01F7/02

    CPC classification number: F16M11/14 ,  F16M11/08 ,  F16M11/16 ,  F16M11/2021 ,  F16M13/02 ,  F16M13/08 ,  F16M2200/022 ,  G03B17/561 ,  G03B17/563 ,  G03B17/566

    Abstract: An apparatus and method for the magnetic-based, releasable and position adjustable attachment of an article to a support. The device is well suited for use with cameras, spotting scopes, navigational devices, distance finders, sensors, lights and other devices, but is not limited to use with these articles. Various embodiments are disclosed including several magnetic-based releasable attachment configurations, various positioning and position locking mechanisms, multiple ways to attach to an ancillary article, and anti-rotation mechanisms, among other aspects of the present invention.

    Abstract translation: 一种用于将物品磁性，可释放和位置可调节地附接到支撑件的装置和方法。 该设备非常适合用于相机，发现示波器，导航设备，测距仪，传感器，灯和其他设备，但不限于与这些物品一起使用。 公开了各种实施例，包括几个基于磁性的可释放的附接配置，各种定位和位置锁定机构，附接到辅助制品的多种方式，以及防旋转机构以及本发明的其它方面。

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