公开(公告)号：US20120172655A1

公开(公告)日：2012-07-05

申请号：US13343617

申请日：2012-01-04

Applicant: Robert L. Campbell ,  Keif Fitzgerald ,  William James Harrison ,  Boris Leschinsky ,  Thomas M. Mallison ,  Mark W. McBride ,  Adam Roslund ,  Daniel A. Walters ,  Phyllis Yuen

Inventor： Robert L. Campbell ,  Keif Fitzgerald ,  William James Harrison ,  Boris Leschinsky ,  Thomas M. Mallison ,  Mark W. McBride ,  Adam Roslund ,  Daniel A. Walters ,  Phyllis Yuen

IPC: A61M1/10 ,  A61M25/00

CPC classification number: A61M25/04 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M2025/0024 ,  A61M2025/0096

Abstract: Disclosed herein are heart pumps that include a catheter assembly and that can be applied percutaneously. Some embodiments include a locking device that prevents components of the catheter assembly from being separated when in use. The catheter assembly can include an expandable tip. In some embodiments, the catheter assembly includes a housing having a wall structure, a portion of which can have a bulbuous shape or can be deformable. In other embodiments, the housing can be configured to reduce fluttering or deflection of the housing and/or to maintain a gap between the housing and an impeller blade disposed therein.

Abstract translation: 本文公开了包括导管组件并且可以经皮应用的心脏泵。 一些实施例包括锁定装置，其防止导管组件的组件在使用时被分离。 导管组件可包括可扩张尖端。 在一些实施例中，导管组件包括具有壁结构的壳体，其一部分可具有球形形状或可变形。 在其他实施例中，壳体可以被配置为减少壳体的颤动或偏转和/或在壳体和设置在其中的叶轮叶片之间保持间隙。

公开(公告)号：US20100125322A1

公开(公告)日：2010-05-20

申请号：US12271053

申请日：2008-11-14

Applicant: Keif Fitzgerald ,  Leticia Castillon

Inventor： Keif Fitzgerald ,  Leticia Castillon

IPC: A61F2/82

CPC classification number: A61F2/95 ,  A61F2002/9665

Abstract: A stent delivery catheter system having a reinforcing tether member secured to the catheter such that the catheter is provided with an improved combination of an enhanced tensile strength together with other catheter performance characteristics such as low profile and high flexibility.

Abstract translation: 一种支架输送导管系统，其具有固定到导管的加强系绳构件，使得导管具有增强的拉伸强度与其它导管性能特征（例如低轮廓和高柔性）的改进组合。

公开(公告)号：US20090099641A1

公开(公告)日：2009-04-16

申请号：US12334071

申请日：2008-12-12

Applicant: Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

Inventor： Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

IPC: A61F2/06 ,  A61F11/00 ,  A61M29/00

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M2025/0098

Abstract: The invention is directed a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 本发明涉及一种用于在包括控制手柄和导管部分的身体中植入自扩张医疗装置的递送系统。 所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

公开(公告)号：US20070191926A1

公开(公告)日：2007-08-16

申请号：US11353391

申请日：2006-02-14

Applicant: Alexander Nikanorov ,  Keif Fitzgerald ,  Steven Tyler ,  Boris Anukhin

Inventor： Alexander Nikanorov ,  Keif Fitzgerald ,  Steven Tyler ,  Boris Anukhin

IPC: A61F2/06

CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/825 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2230/0054

Abstract: An expandable stent has larger cells located at the distal end of the stent than in the body portion so that a catheter balloon can more easily protrude into the cells to increase stent retention relative to the balloon. The intravascular stent has a plurality of cylindrical rings connected by links, the spacing of which is a factor in defining the cell size. The stent can be compressed or crimped onto a balloon catheter to a very low profile and maintain a high degree of stent retention due to increased spacing between rings in the region of the distal end ring.

Abstract translation: 可扩张支架具有位于支架远端的较大的细胞，而不是在体部，使得导管球囊可以更容易地突出到细胞中，以增加相对于球囊的支架保留。 血管内支架具有通过链节连接的多个圆柱形环，其间距是限定细胞大小的因素。 可以将支架压缩或卷曲到气球导管上以非常低的轮廓并且由于远端环区域中的环之间的间隔增加而保持高度的支架保持。

公开(公告)号：US20070112409A1

公开(公告)日：2007-05-17

申请号：US11613827

申请日：2006-12-20

Applicant: Patrick Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

Inventor： Patrick Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

IPC: A61F2/84

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M2025/0098

Abstract: The invention is directed a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 本发明涉及一种用于在包括控制手柄和导管部分的身体中植入自扩张医疗装置的递送系统。 所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

公开(公告)号：US20070055342A1

公开(公告)日：2007-03-08

申请号：US11580431

申请日：2006-10-13

Applicant: Patrick Wu ,  Keif Fitzgerald ,  Stephanie Klocke

Inventor： Patrick Wu ,  Keif Fitzgerald ,  Stephanie Klocke

IPC: A61F2/06

CPC classification number: A61M25/0023 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M25/0021 ,  A61M2025/006 ,  A61M2025/0062 ,  A61M2025/0098 ,  A61M2025/0183 ,  A61M2025/0681

Abstract: The invention is directed to a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 本发明涉及一种用于将自扩张医疗装置植入体内的递送系统，其包括控制手柄和导管部分。 所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

公开(公告)号：US08779328B2

公开(公告)日：2014-07-15

申请号：US12757842

申请日：2010-04-09

Applicant: Boris Anukhin ,  Larry Baughman ,  Pamela A. Kramer-Brown ,  Neil Burkhart ,  Li Chen ,  Duane M. DeMorre ,  Keif Fitzgerald ,  Gregory W. Johnson ,  Z. C. Lin ,  David Mackiewicz ,  Karim S. Osman ,  Randolf von Oepen ,  William E. Webler, Jr. ,  Travis R. Yribarren

Inventor： Boris Anukhin ,  Larry Baughman ,  Pamela A. Kramer-Brown ,  Neil Burkhart ,  Li Chen ,  Duane M. DeMorre ,  Keif Fitzgerald ,  Gregory W. Johnson ,  Z. C. Lin ,  David Mackiewicz ,  Karim S. Osman ,  Randolf von Oepen ,  William E. Webler, Jr. ,  Travis R. Yribarren

IPC: B23K26/38 ,  B23K26/40 ,  A61F2/06 ,  A61F2/07

CPC classification number: B23K26/4005 ,  A61F2/07 ,  A61F2/91 ,  B23K26/16 ,  B23K26/38 ,  B23K26/40 ,  B23K26/402 ,  B23K2101/04 ,  B23K2101/06 ,  B23K2103/50

Abstract: Methods for making devices include providing a tubular member to be formed into a device, placing a removable sacrificial block material in the lumen of the tubular member and laser cutting the tubular member. A tubular member made from nickel-titanium alloy can be tightly adhered to a sacrificial sleeve utilizing the phase changes associated with nickel-titanium. A mandrel which includes an enlarged diameter section causes the workpiece to expand slightly within its elastic deformation range to dislodge islands from the workpiece. Such a mandrel could be formed from a tubular member which has a central lumen that can be used to deliver a pressurized medium to “blast” islands from the workpiece.

Abstract translation: 制造装置的方法包括提供要形成装置的管状构件，将可移除的牺牲块材料放置在管状构件的内腔中并激光切割管状构件。 利用与镍 - 钛相关联的相变，由镍 - 钛合金制成的管状部件可以紧密地粘附到牺牲套管上。 包括扩大直径部分的心轴使得工件在其弹性变形范围内稍微膨胀以从工件移除岛。 这种心轴可以由管状构件形成，该管状构件具有可用于将加压介质输送到工件的“鼓风”岛的中心腔。

公开(公告)号：US08500791B2

公开(公告)日：2013-08-06

申请号：US13557303

申请日：2012-07-25

Applicant: Hao-Ming Hsiao ,  Keif Fitzgerald ,  Boris Anukhin

Inventor： Hao-Ming Hsiao ,  Keif Fitzgerald ,  Boris Anukhin

IPC: A61F2/06

CPC classification number: A61F2/06 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2230/0013

Abstract: System including a delivery catheter and a stent disposed at a distal end of the delivery catheter. The stent includes a plurality of radially expandable rings disposed adjacent to one another to define a tubular member having a proximal end portion, and a distal end portion, and a middle portion, each of the radially expandable rings including a plurality of strut members. The middle portion of the tubular member include a plurality of interconnection members extending between longitudinally adjacent expandable rings, the number of the plurality of the interconnection members being greater than that of the end portion of the tubular member. The stent also includes a transition section between the end portion and the middle portion, the transition section including at least one open cell and at least one closed cell. The stent can be self-expandable or balloon expandable.

Abstract translation: 包括输送导管和设置在输送导管远端的支架的系统。 所述支架包括彼此相邻设置的多个可径向扩张的环，以限定具有近端部分的管状构件，以及远端部分和中间部分，每个所述径向可扩张环包括多个支柱构件。 管状构件的中间部分包括在纵向相邻的可膨胀环之间延伸的多个互连构件，多个互连构件的数量大于管状构件的端部的数量。 支架还包括在端部和中间部分之间的过渡部分，过渡部分包括至少一个开放电池和至少一个闭合电池。 支架可以是自扩张的或气囊扩张的。

公开(公告)号：US08485961B2

公开(公告)日：2013-07-16

申请号：US13343617

申请日：2012-01-04

Applicant: Robert L. Campbell ,  Keif Fitzgerald ,  William James Harrison ,  Boris Leschinsky ,  Thomas M. Mallison ,  Mark W. McBride ,  Adam Roslund ,  Daniel A. Walters ,  Phyllis Yuen

Inventor： Robert L. Campbell ,  Keif Fitzgerald ,  William James Harrison ,  Boris Leschinsky ,  Thomas M. Mallison ,  Mark W. McBride ,  Adam Roslund ,  Daniel A. Walters ,  Phyllis Yuen

IPC: A61N1/362

CPC classification number: A61M25/04 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M2025/0024 ,  A61M2025/0096

Abstract: Disclosed herein are heart pumps that include a catheter assembly and that can be applied percutaneously. Some embodiments include a locking device that prevents components of the catheter assembly from being separated when in use. The catheter assembly can include an expandable tip. In some embodiments, the catheter assembly includes a housing having a wall structure, a portion of which can have a bulbuous shape or can be deformable. In other embodiments, the housing can be configured to reduce fluttering or deflection of the housing and/or to maintain a gap between the housing and an impeller blade disposed therein.

Abstract translation: 本文公开了包括导管组件并且可以经皮应用的心脏泵。 一些实施例包括锁定装置，其防止导管组件的组件在使用时被分离。 导管组件可包括可扩张尖端。 在一些实施例中，导管组件包括具有壁结构的壳体，其一部分可具有球形形状或可变形。 在其他实施例中，壳体可以被配置为减少壳体的颤动或偏转和/或在壳体和设置在其中的叶轮叶片之间保持间隙。

公开(公告)号：US08323327B2

公开(公告)日：2012-12-04

申请号：US12857467

申请日：2010-08-16

Applicant: Nianjiong Joan Bei ,  Keif Fitzgerald ,  Patrick C. Saxton ,  Zhicheng Lin ,  Steven A. Tyler ,  Joanna Lubas

Inventor： Nianjiong Joan Bei ,  Keif Fitzgerald ,  Patrick C. Saxton ,  Zhicheng Lin ,  Steven A. Tyler ,  Joanna Lubas

IPC: A61F2/06

CPC classification number: A61F2/958 ,  A61F2/013 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2002/9583 ,  A61F2230/0006 ,  A61F2230/008

Abstract: A catheter system for implanting an endoprosthesis at a treatment site in a patient's body lumen. The catheter includes an elongated shaft outer member and a stent sheath distal portion and a self-expanding stent radially restrained in a collapsed configuration within the stent sheath distal portion. A balloon catheter dimensioned for relative axial movement within the shaft outer member has an elongated shaft having an inflation lumen and a device receiving lumen. A stent stop secured to the balloon catheter is reversibly radially expandable to deploy from a collapsed to a radially expanded configuration. In the expanded configuration, the stent stop prevents longitudinal displacement of the stent. A balloon is located on a distal shaft section is releasably locked with respect to the shaft outer member and slidably disposed therein in an unlocked configuration.

Abstract translation: 一种用于在患者体腔内的治疗部位植入内假体的导管系统。 导管包括细长轴外部构件和支架护套远端部分以及在扩张器护套远端部分中以收缩构型径向约束的自扩张支架。 用于在轴外部构件内进行相对轴向移动的气囊导管具有细长轴，该细长轴具有充气腔和容纳腔的装置。 固定到气囊导管的支架止动器可逆地径向展开，从展开状态展开到径向展开的构型。 在扩张结构中，支架止动件防止支架的纵向位移。 位于远侧轴部上的气囊相对于轴外部构件可释放地锁定并且以可解锁的构造可滑动地设置在其中。