摘要:
The invention encompasses a series pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
摘要:
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
摘要:
Improved manganese peroxidases, polynucleotides encoding improved manganese peroxidase and vectors and cells thereof are provided, as well as methods for converting a cellulose-containing biomass feedstock to ethanol using improved manganese peroxidases and cells expressing a heterologous manganese peroxidase as disclosed herein.
摘要:
A surgical clamp is provided that is applied through a laparoscopic port and is used for clamping off a portion of an organ. The surgical clamp comprises an elongated flexible bioabsorbable polymer band laced with a hemostatic agent. The band has a proximal end and a distal end. A bioabsorbable polymer tie secures in place the proximal end of the band to the distal end of the band. A conductive wire snare is provided to cut and cauterize a target.
摘要:
Electrostatic footwear in the form of a cover with a sole and an upper having an opening to receive the foot or shoe of a user. The opening may be provided with elastic or an elastic cuff for retention about the user. The cover may be worn over the foot or the shoe of a user. The cover has an excess electrical charge to attract particulate matter including but not limited to dust, dirt, pollen, and dander. The electrostatic charge causes the particulate matter to be drawn and held thereon as the user moves about. The sole may include anti-skid material over a limited portion thereof to prevent the user from sliding or slipping.
摘要:
The invention encompasses a series pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
摘要:
A dispensing package with single use integral thermal engine for a product has an upper product tray having a product well for holding the product with a peelable lid removably attached to the upper product tray, covering the product contained in the product well. A lower base tray, having a thermal engine well, is attached to the bottom of the upper product tray. A thermal engine is contained within the thermal engine well. The thermal engine has an oxidizer pouch containing an oxidizing agent and fuel reactive to the oxidizing agent. Applying pressure to the oxidizer pouch causes the oxidizer pouch to rupture or burst thus dispensing the oxidizing agent into the thermal engine well mixing with the fuel and reacting to generate heat.