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21.发明授权公开(公告)号：US11167134B2
公开(公告)日：2021-11-09
申请号：US16208007
申请日：2018-12-03
摘要： A system for providing biphasic stimulation is disclosed. The system includes an electrode, an antenna coupled to a transmitter, a capacitor, a power supply, a backscatter load selectively coupled to the antenna via a switching device, a plurality of switches, and a controller configured to control the switching device to output, by the antenna, an acknowledgement signal to the transmitter responsive to receiving the power. The controller is further configured to control the plurality of switches to electrically couple a first plate of the capacitor to the electrode to provide a first nerve stimulation signal having a first polarity, and electrically couple a second plate of the capacitor to the electrode to provide a second nerve stimulation signal having a second polarity opposite the first polarity. The system further includes a housing encapsulating the antenna, the capacitor, the power supply, the backscatter load, the switches, and the controller.
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公开(公告)号：US11125562B2
公开(公告)日：2021-09-21
申请号：US15459557
申请日：2017-03-15
发明人： Robin Mark Adrian Dawson , Juha-Pekka J. Laine , Murali V. Chaparala , Charles Arant , Matthew T. Jamula
摘要： A navigation system includes a monocentric lens and one or more curved image sensor arrays disposed parallel and spaced apart from the lens to capture respective portions, not all, of the field of view of the lens.
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公开(公告)号：US20210238526A1
公开(公告)日：2021-08-05
申请号：US17240634
申请日：2021-04-26
发明人： Jonathan R. Coppeta , Joseph L. Charest , Else M. Vedula , Jeffrey T. Borenstein , Abigail June Spencer , Brett C. Isenberg
IPC分类号： C12M1/12 , C12M1/32 , C12M3/06 , C12M1/00 , G01N33/50 , C12N5/071 , C12M1/36 , C12M3/00 , C12M1/34 , C12M1/42
摘要： The methods and systems described herein provide a cell culture platform with an array of tissue modeling environments and dynamic control of fluid flow. The cell culture platform includes an array of wells that are fluidically coupled by microchannel structures. The dynamically controlled flow of fluid interacts with cells grown within the microchannels.
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公开(公告)号：US20210231780A1
公开(公告)日：2021-07-29
申请号：US16773145
申请日：2020-01-27
IPC分类号： G01S7/481 , G01S7/4912
摘要： A LiDAR system includes a light source and an arrayed micro-optic configured to receive light from the light source so as to produce and project a two-dimensional array of light spots on a scene. The LiDAR system also includes receiver optics having an array of optical detection sites configured so as to be suitable for establishing a one-to-one correspondence between light spots in the two-dimensional array and optical detection sites in the receiver optics. The LiDAR system further includes a beamsplitter and a lens. The LiDAR system may also include a mask placed in the light path between the beamsplitter and the receiver optics. Alternatively, the LiDAR system may include a controller programmed to activate or deactivate each optical detection site.
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公开(公告)号：US20210220823A1
公开(公告)日：2021-07-22
申请号：US16755505
申请日：2018-10-12
IPC分类号： B01L3/00 , C12Q1/6874 , B01L7/00 , C12Q1/6837 , B04B5/04 , B04B3/00
摘要： Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency.
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公开(公告)号：US11054394B2
公开(公告)日：2021-07-06
申请号：US16115742
申请日：2018-08-29
摘要： A computer-implemented method is described for detecting, identifying and locating an object feature in a ferromagnetic object. At least one hardware processor executes program instructions to: define a planned scan trajectory for scanning the ferromagnetic object with a sensor array comprising a plurality of magnetometer sensors, measure magnetic fields of the ferromagnetic object with the sensor array along an actual scan trajectory at locations adjacent to the ferromagnetic material to produce object scanning data representing magnetic characteristics of the ferromagnetic object along the actual scan trajectory. The actual scan trajectory includes deviation motion of the scanning array from the planned scan trajectory. The deviation motion is then compensated for to identify and locate the object feature in the ferromagnetic object. The compensation includes adjusting the object scanning data for the deviation motion and/or using a feature model that reflects the deviation motion.
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公开(公告)号：US20210154379A1
公开(公告)日：2021-05-27
申请号：US17100309
申请日：2020-11-20
发明人： Vishal Tandon , Ernest Kim , Jeffrey Borenstein
摘要： The present disclosure provides a handpiece for trans-canal delivery of a therapeutic substance to the inner ear. The handpiece can be inserted into the middle ear via a surgical tympanotomy approach. The handpiece can be integrated with a micropump and a fluid reservoir. The handpiece can enable a controlled injection of a therapeutic substance directly through the round window membrane and into the inner ear. The direct delivery of the therapeutic substance to the inner ear can enable the delivery of a precise amount of therapeutic substance into the inner ear. The micropump can include a self-contained fluid reservoir that can provide predetermined volumes of fluid to precise areas of the patient.
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28.发明授权公开(公告)号：US11009770B2
公开(公告)日：2021-05-18
申请号：US16540650
申请日：2019-08-14
发明人： Gregg E. Favalora
IPC分类号： G02F1/335
摘要： A light field generation system includes a two dimensional emitter array for projecting light and a directionally-sensitive optical element in front of the emitter array but before a directional diffuser. Certain classes of emitters are intended to project information principally along one axis (e.g. amplitude modulated in the horizontal plane, i.e. so that each eye sees a potentially different image) and are the basis of horizontal-parallax-only (HPO) displays. Examples include surface acoustic wave (SAW) modulators, such as edge-emitting or surface-emitting modulators. They often project undesired or stray light along directions along a different axis (e.g. vertically) and the diffuser will also spread the visibility of the stray light field components. Thus, the directionally-sensitive optical element will improve contrast in this scenario.
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公开(公告)号：US20210121687A1
公开(公告)日：2021-04-29
申请号：US16921486
申请日：2020-07-06
发明人： John Burns, IV , Julianne Grainger , Bryan McLaughlin , Tirunelveli S. Sriram , John Lachapelle
IPC分类号： A61N1/05
摘要： The present disclosure discusses a method of manufacturing an implantable neural electrode. The method includes cutting a metal layer to form a plurality of electrode sites, contact pads and metal traces connecting the electrode sites to the contact pads. A first silicone layer including a mesh is formed and coupled to the metal layer. A second silicone layer is formed and laminated to the first silicone layer coupled with the metal layer. Holes are formed in the first or second silicone layer exposing the contact pads and electrode sites. Wires are welded to the exposed contact pads and a third layer of silicone is overmolded over the contact pads and wires.
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公开(公告)号：US10982959B2
公开(公告)日：2021-04-20
申请号：US15696931
申请日：2017-09-06
摘要： An ensemble of motion sensors is tested under known conditions to automatically ascertain instrument biases, which are modeled as autoregressive-moving-average (ARMA) processes in order to construct a Kalman filter. The calibration includes motion profiles, temperature profiles and vibration profiles that are operationally significant, i.e., designed by means of covariance analysis or other means to maximize, or at least improve, the observability of the calibration model's structure and coefficients relevant to the prospective application of each sensor.
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