公开(公告)号：US20050229468A1

公开(公告)日：2005-10-20

申请号：US10933856

申请日：2004-09-03

Applicant: Serge Zaderey ,  Steven Timm ,  Gary Williams ,  Victoria Peters ,  Laura Peter ,  Tim Lesser ,  Tim O'Connor

Inventor： Serge Zaderey ,  Steven Timm ,  Gary Williams ,  Victoria Peters ,  Laura Peter ,  Tim Lesser ,  Tim O'Connor

IPC: F41G1/38

CPC classification number: F41G1/38

Abstract: A reticle of a projectile weapon aiming system such as a riflescope includes a primary aiming mark adapted to be sighted-in at a first selected range and further includes a plurality of secondary aiming marks spaced apart below the primary aiming mark. The secondary aiming marks are positioned to compensate for ballistic drop at preselected incremental ranges beyond the first selected range, for a selected group of ammunition having similar ballistic characteristics. Angles subtended by adjacent aiming marks of the reticle can be adjusted by changing the optical power of the riflescope, to thereby compensate for ballistic characteristics of different ammunition. In some embodiments, the reticle includes a set of windage aiming marks spaced apart along at least one secondary horizontal axis intersecting a selected one of the secondary aiming marks, to facilitate compensation for the effect of crosswinds on the trajectory of the projectile.

Abstract translation: 射击武器瞄准系统如路镜的掩模版包括适于在第一选定范围内被瞄准的主瞄准标记，并且还包括在主瞄准标记下方间隔开的多个次瞄准标记。 第二瞄准标记被定位成补偿具有类似弹道特性的选定组的弹药的超出第一选定范围的预选增量范围的弹道降落。 可以通过改变步枪镜的光功率来调整由掩模版的相邻瞄准标记所对向的角度，从而补偿不同弹药的弹道特性。 在一些实施例中，掩模版包括沿着与所选择的第二瞄准标记相交的至少一个副水平轴线间隔开的一组风向瞄准标记，以便于补偿侧风对射弹轨迹的影响。

公开(公告)号：US12145396B2

公开(公告)日：2024-11-19

申请号：US16693502

申请日：2019-11-25

Applicant: Tim O'Connor

Inventor： Tim O'Connor

IPC: B43L1/00 ,  B42F13/16 ,  B43L1/10 ,  G09B19/00 ,  G09F1/02 ,  G09F1/06 ,  G09F7/00 ,  G09F7/06

Abstract: A series of devices that allow for embedding of an image as a background while also affording the user the ability to write and print on the surface, with erasable capabilities, thus providing a multifunctional product for use in numerous industries. The devices are manufactured from predominately corrugated plastic. In one embodiment a one piece, removably attachable, cabinet system and graphic display system. In an additional embodiment, a writable board, or peg board comprising a front panel and a rear panel wherein the panels are interconnected by parallel rows, or corrugations, these panels include a writable and erasable surface. The present invention relates to assemblies of corrugated systems to better serve personal, business, and educational needs.

公开(公告)号：US20130066257A1

公开(公告)日：2013-03-14

申请号：US13608237

申请日：2012-09-10

Applicant: Martyn Folan ,  John Clarke ,  Aiden Flanagan ,  Anthony Malone ,  Tim O'Connor

Inventor： Martyn Folan ,  John Clarke ,  Aiden Flanagan ,  Anthony Malone ,  Tim O'Connor

IPC: A61B17/22 ,  A61M37/00

CPC classification number: A61M25/104 ,  A61B17/320725 ,  A61B2017/22061 ,  A61M25/1002 ,  A61M2025/1004 ,  A61M2025/105 ,  A61M2025/1059 ,  A61M2025/1086

Abstract: A medical balloon assembly including an inflatable balloon and at least one cutting element extending from the balloon is disclosed. The inflatable balloon includes an outer wall facing outward and an inner wall facing outward. The cutting element comprises a plurality of openings therein including a first opening and a second opening. The first opening is closed off by a portion of the outer wall. The cutting element further includes a passageway extending from the first opening to the second opening. The passageway is defined by the cutting element and the portion of the outer wall which closes off the passageway. The passageway may contain a therapeutic agent.

Abstract translation: 公开了一种医用气囊组件，其包括可充气球囊和从球囊延伸的至少一个切割元件。 充气气囊包括面向外的外壁和面向外的内壁。 切割元件包括多个开口，其中包括第一开口和第二开口。 第一开口被外壁的一部分封闭。 切割元件还包括从第一开口延伸到第二开口的通道。 通道由切割元件和封闭通道的外壁部分限定。 通道可以含有治疗剂。

公开(公告)号：US20090264975A1

公开(公告)日：2009-10-22

申请号：US12425791

申请日：2009-04-17

Applicant: Aiden FLANAGAN ,  John KILCOOLEY ,  Tim O'CONNOR ,  Barry O'BRIEN ,  Dominique SEIDEL ,  Michael KUEHLING ,  Torsten SCHEUERMANN ,  Jan WEBER

Inventor： Aiden FLANAGAN ,  John KILCOOLEY ,  Tim O'CONNOR ,  Barry O'BRIEN ,  Dominique SEIDEL ,  Michael KUEHLING ,  Torsten SCHEUERMANN ,  Jan WEBER

IPC: A61F2/82 ,  A61L33/00

CPC classification number: A61L29/10 ,  A61L29/16 ,  A61L31/082 ,  A61L31/16 ,  A61L2300/602 ,  A61L2300/61

Abstract: In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of forming coatings on medical devices and methods of delivering therapeutic agents to body sites are also disclosed.

Abstract translation: 在一个方面，医疗装置具有第一构造和第二构造，包含治疗剂的贮存器和设置在贮存器上方的阻挡层，其中阻挡层包括无机材料。 在另一方面，医疗装置具有容纳治疗剂的储存器，设置在贮存器上方的阻挡层，其中所述阻挡层包括无机材料，以及设置在所述阻挡层和所述医疗装置的表面之间的可溶胀材料，其中 可膨胀材料是暴露于含水环境时膨胀的材料。 在另一方面，医疗装置具有多层涂层，其具有交替的储层和阻挡层，以及穿透多层涂层的至少部分厚度的多个挖掘区域。 在另一方面，医疗装置具有包含嵌段共聚物的聚合物层，其中聚合物层含有治疗剂，以及设置在聚合物层上的阻挡层，其中阻挡层包含无机材料，其中， 阻挡层具有多个不连续性。 还公开了在医疗装置上形成涂层的方法和将治疗剂递送到身体部位的方法。

公开(公告)号：US20090123521A1

公开(公告)日：2009-05-14

申请号：US11983796

申请日：2007-11-09

Applicant: Jan Weber ,  Aiden Flanagan ,  Tim O'Connor ,  Barry J. O'Brien ,  John Clarke ,  David McMorrow

Inventor： Jan Weber ,  Aiden Flanagan ,  Tim O'Connor ,  Barry J. O'Brien ,  John Clarke ,  David McMorrow

IPC: A61F2/00 ,  A61K31/337 ,  A61N1/04

CPC classification number: A61F2/06 ,  A61F2250/0068 ,  A61L27/30 ,  A61L27/54 ,  A61L31/082 ,  A61L31/16 ,  A61L2300/00 ,  A61L2400/12 ,  A61N1/05

Abstract: According to an aspect of the invention, medical devices are provided, which include a nanoparticle-derived inorganic layer disposed over a least a portion of structure that includes a substrate, and optionally, a therapeutic-agent-containing layer disposed over at least a portion of the substrate. In some embodiments, the inorganic layer is a nanoporous inorganic layer. Other aspects of the invention comprise methods for forming such medical device.

Abstract translation: 根据本发明的一个方面，提供了医疗装置，其包括设置在包括基底的结构的至少一部分上的纳米颗粒衍生的无机层，以及任选地，设置在至少一部分上的治疗剂含有层 的基底。 在一些实施方案中，无机层是纳米多孔无机层。 本发明的其它方面包括用于形成这种医疗装置的方法。

公开(公告)号：US20090081271A1

公开(公告)日：2009-03-26

申请号：US11860188

申请日：2007-09-24

Applicant: John Clarke ,  Tim O'Connor ,  Yixin Xu ,  Barry J. O'Brien

Inventor： John Clarke ,  Tim O'Connor ,  Yixin Xu ,  Barry J. O'Brien

IPC: A61F2/04 ,  A61F2/02

CPC classification number: A61F2/82 ,  A61F2/00 ,  A61F2/01 ,  A61F2/04 ,  A61F2/91 ,  A61F2220/0058 ,  A61F2250/0068

Abstract: An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a pre-formed filter insert disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device in vivo.

Abstract translation: 提供了一种植入式或可插入的医疗装置，其包括作为部件：（a）底物组分，其包含至少部分地填充有包含第一治疗剂的治疗剂材料的凹陷，和（b）预形成 过滤器插入件设置在凹陷中，使得其在体内植入或插入装置时调节化学物质在装置的凹陷和外部之间的运输。

公开(公告)号：US20060206191A1

公开(公告)日：2006-09-14

申请号：US11431826

申请日：2006-05-11

Applicant: Jan Weber ,  Tim O'Connor

Inventor： Jan Weber ,  Tim O'Connor

IPC: A61F2/84

CPC classification number: A61M25/104 ,  A61F2/958 ,  A61F2002/9583 ,  A61M25/1027 ,  A61M2025/1081

Abstract: In order to minimize the potential for damage to bio-compatible and/or therapeutic-containing stent coatings, there is provided a compliant elastic sheath over layer between a non-compliant stent expansion balloon and an unexpanded stent, which is secured over the balloon with a securing crimp. This stent deployment assembly, which is mounted on a catheter, is maneuvered through a patient's body to a desired deployment site and then inflated to expand the stent to the desired diameter. During expansion, the compliant elastic material between the stent and the non-compliant balloon prevents non-compliant balloon-induced damage to the stent's coating, as well as preventing degradation of the non-compliant balloon by, for example, stent-caused punctures. The deflated non-compliant stent expansion balloon and compliant elastic sheath are then withdrawn from the patient's body, leaving the deployed stent at the desired implantation site with its coating substantially intact.

公开(公告)号：US20060136871A1

公开(公告)日：2006-06-22

申请号：US10905173

申请日：2004-12-20

Applicant: Tim O'Connor ,  Eric Seal ,  Michael Inniss

Inventor： Tim O'Connor ,  Eric Seal ,  Michael Inniss

IPC: G06F9/44

CPC classification number: G06Q10/06

Abstract: A method for holistic project management may include presenting a graphical user interface for a user to enter project information for a project. The method may also include determining a priority for the project based on an impact of the project to each of a plurality of predetermined drivers.

Abstract translation: 用于整体项目管理的方法可以包括呈现图形用户界面，供用户输入项目的项目信息。 该方法还可以包括基于项目对多个预定驱动器中的每一个的影响来确定项目的优先级。

公开(公告)号：US20060038027A1

公开(公告)日：2006-02-23

申请号：US11237685

申请日：2005-09-29

Applicant: Tim O'Connor ,  Gabriel Sobrino

Inventor： Tim O'Connor ,  Gabriel Sobrino

IPC: A01G25/09 ,  A61L33/00 ,  A62C5/02 ,  B05B15/00

CPC classification number: B05B7/066

Abstract: An apparatus and method for spray deposition of small targets, such as medical devices like stents. The apparatus includes a spray nozzle body which has a fine bore diameter to pressurize the coating material within the nozzle body thereby dampening vibration of the nozzle body during operation and stabilizing the spray coating plume. In another embodiment, a coating method is disclosed in which a finer atomized spray droplet size is achieved by pre-filming the coating material onto a flat face before entraining the coating material within the atomizing fluid, which improves manufacturing repeatability, reduces coating variances, and increases therapeutic dosage predictability. In certain embodiments of the invention, the coating materials include therapeutic agents and biologically active materials.

Abstract translation: 用于喷雾沉积小靶的装置和方法，例如诸如支架的医疗装置。 该装置包括具有细孔直径以对喷嘴体内的涂层材料加压的喷嘴体，从而在操作期间抑制喷嘴体的振动并稳定喷涂羽流。 在另一个实施方案中，公开了一种涂覆方法，其中通过在夹带雾化流体内的涂层材料之前将涂层材料预成膜到平坦的表面上来实现更精细的雾化喷雾液滴尺寸，这提高了制造重复性，降低了涂层的变化， 增加治疗剂量可预测性。 在本发明的某些实施方案中，涂层材料包括治疗剂和生物活性材料。

公开(公告)号：US06979473B2

公开(公告)日：2005-12-27

申请号：US10799589

申请日：2004-03-15

Applicant: Tim O'Connor ,  Gabriel Sobrino

Inventor： Tim O'Connor ,  Gabriel Sobrino

IPC: B05B7/06 ,  B05D3/00

CPC classification number: B05B7/066

Abstract: A method for spray deposition of small targets, such as medical devices like stents. The method includes the steps of positioning a spray nozzle body, which has a fine bore diameter to pressurize the coating material within the nozzle body, near a medical device, and dampening vibration of the nozzle body during operation by maintaining a steady back pressure in the coating material line sufficient to eliminate or minimize vibration modes from external and internal sources; and stabilizing the spray coating plume. In another embodiment, a coating method is disclosed in which a finer atomized spray droplet size is achieved by pre-filming the coating material onto a flat face before entraining the coating material within the atomizing fluid, which improves manufacturing repeatability, reduces coating variances, and increases therapeutic dosage predictability. In certain embodiments of the invention, the coating materials include therapeutic agents and biologically active materials.

Abstract translation: 用于喷雾沉积小靶的方法，例如诸如支架的医疗装置。 该方法包括以下步骤：定位喷嘴体，其具有细孔直径以在喷嘴体内靠近医疗装置加压涂层，以及在操作期间通过保持稳定的背压来抑制喷嘴体的振动 涂层材料线足以消除或最小化来自外部和内部源的振动模式; 并稳定喷涂羽流。 在另一个实施方案中，公开了一种涂覆方法，其中通过在夹带雾化流体内的涂层材料之前将涂层材料预成膜到平坦的表面上来实现更精细的雾化喷雾液滴尺寸，这提高了制造重复性，降低了涂层的变化， 增加治疗剂量可预测性。 在本发明的某些实施方案中，涂层材料包括治疗剂和生物活性材料。