公开(公告)号：US20090291607A1

公开(公告)日：2009-11-26

申请号：US12307384

申请日：2006-07-14

申请人： James H. Wang ,  Aimin He

发明人： James H. Wang ,  Aimin He

IPC分类号： B32B5/26 ,  C08G63/91 ,  C08J5/10

CPC分类号： D01F6/84 ,  B32B5/26 ,  C08G63/16 ,  C08G63/916 ,  D04H1/56 ,  D04H3/011 ,  D04H3/153 ,  D04H3/16 ,  Y10T442/66 ,  Y10T442/68

摘要： A method for forming a biodegradable aliphatic-aromatic copolyester suitable for use in fibers is provided. In one embodiment, for example, an aliphatic-aromatic copolyester is melt blended with an alcohol to initiate an alcoholysis reaction that results in a copolyester having one or more hydroxyalkyl or alkyl terminal groups. By selectively controlling the alcoholysis conditions (e.g., alcohol and copolymer concentrations, catalysts, temperature, etc.), a modified aliphatic-aromatic copolyester may be achieved that has a molecular weight lower than the starting aliphatic-aromatic polymer. Such lower molecular weight polymers also have the combination of a higher melt flow index and lower apparent viscosity, which is useful in a wide variety of fiber forming applications, such as in the meltblowing of nonwoven webs.

摘要翻译： 提供了一种形成适用于纤维的可生物降解的脂族 - 芳族共聚酯的方法。 在一个实施方案中，例如，脂族 - 芳族共聚酯与醇熔融共混以引发醇解反应，其导致具有一个或多个羟烷基或烷基端基的共聚酯。 通过选择性地控制醇解条件（例如醇和共聚物浓度，催化剂，温度等），可以实现具有低于起始脂族 - 芳族聚合物的分子量的改性脂族 - 芳族共聚酯。 这种低分子量聚合物还具有较高的熔体流动指数和较低的表观粘度的组合，其可用于各种纤维形成应用中，例如在非织造纤维网的熔喷中。

公开(公告)号：US20060199254A1

公开(公告)日：2006-09-07

申请号：US11431321

申请日：2006-05-10

申请人： John Rosazza ,  Ian Fotheringham ,  Tao Li ,  Lacy Daniels ,  Aimin He

发明人： John Rosazza ,  Ian Fotheringham ,  Tao Li ,  Lacy Daniels ,  Aimin He

IPC分类号： C12P7/24 ,  C12N9/02 ,  C07C49/786

CPC分类号： C12N9/0008 ,  C07H21/04

摘要： The invention provides the nucleotide sequence and amino acid sequence for the enzyme carboxylic acid reductase isolated from bacteria. Expression cassettes, vectors, transformed cells, and variants are also provided as methods for use of recombinant biocatalytic reagents in production of synthetic, aromatic, aliphatic and alicyclic aldehydes and alcohols.

摘要翻译： 本发明提供了从细菌分离的酶羧酸还原酶的核苷酸序列和氨基酸序列。 还提供了表达盒，载体，转化细胞和变体作为在合成，芳族，脂族和脂环族醛和醇的生产中使用重组生物催化剂的方法。

公开(公告)号：US09648875B2

公开(公告)日：2017-05-16

申请号：US14347446

申请日：2011-10-28

申请人： David William Koenig ,  Douglas Robert Hoffman ,  Yang Huang ,  Aimin He

发明人： David William Koenig ,  Douglas Robert Hoffman ,  Yang Huang ,  Aimin He

IPC分类号： A01N33/24 ,  A01N59/00 ,  A01N37/16 ,  A01N37/10 ,  A01N25/06 ,  A01N25/30 ,  A47K10/32 ,  A61K8/02 ,  A61K9/70 ,  A61Q17/00 ,  A01N25/08

CPC分类号： A01N33/24 ,  A01N25/08 ,  A01N37/10 ,  A01N59/00 ,  A47K2010/3266 ,  A61K8/0208 ,  A61K9/7007 ,  A61Q17/005 ,  A01N25/30 ,  A01N37/16

摘要： Formulations and wipes for imparting a sporicide to a surface are disclosed herein. To achieve the sporicidal efficacy of the product, a synergistic amount of an amine oxide surfactant and a mixture of oxidants is incorporated into the formulation. The operative sporicidal formulation contains a solvent, an amine oxide surfactant, a water soluble oxidant and a water insoluble oxidant. Typically, the formulation can contain about 0.05 to about 3.7 percent (by weight of the formulation) of an amine oxide surfactant, about 0.5 to about 4 percent (by weight of the formulation) of a water soluble oxidant, and about 0.1 to about 6 percent (by weight of the formulation) of a water insoluble oxidant.

公开(公告)号：US20140170674A1

公开(公告)日：2014-06-19

申请号：US13730805

申请日：2012-12-28

申请人： Aimin He

发明人： Aimin He

IPC分类号： G01N33/558 ,  G01N33/543

CPC分类号： G01N33/558

摘要： This invention discloses an immunochromatographic assay device to detect and quantify analytes. The device utilizes up-converting luminescent probes to detect time-resolved luminescence signals. Because the unconverting luminescent probes can have relatively long emission lifetime, background interference from sample autofluorescence and light scattering from excitation source can be easily eliminated through delayed luminescence detection. Furthermore, the up-converting luminescent probes can be excited by near Infrared (IR) or IR light sources. In comparing with UV and visible lights, the near IR and IR lights can penetrate deeper into sample matrices and more effectively excite the probes, but not the sample matrices, resulting in less background and higher detection sensitivity. A simple and low cost reader can be designed to measure the delayed up-converting luminescence of long lifetime that does not use expensive optical filters and mirrors.

摘要翻译： 本发明公开了一种用于检测和定量分析物的免疫色谱测定装置。 该器件利用上转换发光探针来检测时间分辨发光信号。 因为未转换的发光探针具有相对长的发光寿命，所以通过延迟发光检测可以容易地消除来自样品自发荧光的背景干扰和来自激发源的光散射。 此外，上转换发光探针可以被近红外（IR）或红外光源激发。 与紫外光和可见光相比，近红外和红外光可以更深地渗透到样品基质中，更有效地激发探针，而不是样品基质，导致较少的背景和更高的检测灵敏度。 可以设计简单且低成本的读取器来测量不使用昂贵的光学滤波器和反射镜的长寿命的延迟上变换发光。

公开(公告)号：US20130171624A1

公开(公告)日：2013-07-04

申请号：US13730814

申请日：2012-12-28

申请人： Aimin He

发明人： Aimin He

IPC分类号： G01N33/58

CPC分类号： G01N33/582 ,  G01N33/54326 ,  G01N2458/40

摘要： This invention describes a general magnetic binding assay method to detect the presence and quantity of analyte in a sample. The method uses magnetic particles for separating and concentrating analytes of interest from complex samples and use time-resolved up-converting fluorescence detection technique to provide highly sensitive detection without using expensive optical components such as band-pass filters. The method uses pulsed long wavelength light for excitation and time-delayed luminescence detection, resulting in little interferences from sample matrices. Furthermore, the usage of long wavelength excitation light requires simpler sample preparation and clean-up such as removal of red blood cells, which otherwise will significantly interfere with excitation efficiency of the fluorescence probes.

摘要翻译： 本发明描述了用于检测样品中分析物的存在和量的一般磁结合测定方法。 该方法使用磁性颗粒从复杂样品中分离和浓缩感兴趣的分析物，并使用时间分辨上变换荧光检测技术，以提供高灵敏度检测，而不使用昂贵的光学组件，如带通滤光片。 该方法使用脉冲长波长光进行激发和时间延迟的发光检测，导致样品基质几乎没有干扰。 此外，长波长激发光的使用需要更简单的样品制备和清除，例如去除红细胞，否则将显着干扰荧光探针的激发效率。

公开(公告)号：US20150329798A1

公开(公告)日：2015-11-19

申请号：US14655351

申请日：2012-12-27

申请人： David William KOENIG ,  Mary Kay FOEGEN ,  Corey Thomas CUNNINGHAM ,  Aimin HE ,  Yang HUANG ,  KIMBERLY-CLARK WORLDWIDE, INC.

发明人： David William Koenig ,  Mary Kay Foegen ,  Corey Thomas Cunningham ,  Aimin He ,  Yang Huang

IPC分类号： C11C3/00 ,  A01N65/12 ,  A61F13/84 ,  A01N65/48 ,  A01N65/36 ,  A01N65/28 ,  A01N25/34 ,  A01N65/22

摘要： Methods for adjusting the solubility of a botanical oil in water, along with the resulting modified botanical oil and related products (e.g., treatment compositions, wipes, absorbent articles, etc.) are provided. In one embodiment, the method includes reacting the botanical oil to form a reactive product (e.g., having a hydroxyl group); and attaching a hydrophilic end group (e.g., a carboxylic acid, a carboxylic acid salt, a sugar, etc.) on the reactive product to form a modified botanical oil. The modified botanical oil generally, in most embodiments, has a greater solubility in water than the botanical oil (e.g., a solubility in water of about 10 grams per 100 grams of water or greater, such as completely soluble in water). The botanical oil includes, in one particular embodiment, an essential oil, such as those essential oil that include at least one terpene compound.

摘要翻译： 提供了调节植物油在水中的溶解度以及所得改性植物油和相关产品（例如处理组合物，擦拭物，吸收制品等）的方法。 在一个实施方案中，该方法包括使植物油反应以形成反应性产物（例如具有羟基）; 并将亲水性端基（例如羧酸，羧酸盐，糖等）附着在反应性产物上以形成改性植物油。 在大多数实施方案中，经修饰的植物油在植物油中的溶解度通常比植物油高（例如在水中的溶解度为约10克/ 100克水或更高，例如完全溶于水）。 植物油在一个具体实施方案中包括精油，例如包含至少一种萜烯化合物的那些精油。

公开(公告)号：US07056714B2

公开(公告)日：2006-06-06

申请号：US10386329

申请日：2003-03-11

申请人： John P. Rosazza ,  Ian Fotheringham ,  Tao Li ,  Lacy Daniels ,  Aimin He

发明人： John P. Rosazza ,  Ian Fotheringham ,  Tao Li ,  Lacy Daniels ,  Aimin He

IPC分类号： C12N9/02 ,  C12N1/20 ,  C12N15/00 ,  C12P21/04 ,  C12Q1/26 ,  C12Q1/00 ,  C07H21/04

CPC分类号： C12N9/0008 ,  C07H21/04

摘要： The invention provides the nucleotide sequence and amino acid sequence for the enzyme carboxylic acid reductase isolated from bacteria. Expression cassettes, vectors, transformed cells, and variants are also provided as methods for use of recombinant biocatalytic reagents in production of synthetic, aromatic, aliphatic and alicyclic aldehydes and alcohols.