公开(公告)号：US5399557A

公开(公告)日：1995-03-21

申请号：US30427

申请日：1993-04-07

申请人： Akira Mizuno ,  Mikiko Miya ,  Norio Inomata ,  Toshio Tatsuoka ,  Takafumi Ishihara

发明人： Akira Mizuno ,  Mikiko Miya ,  Norio Inomata ,  Toshio Tatsuoka ,  Takafumi Ishihara

IPC分类号： C07D487/04 ,  A61K31/55

CPC分类号： C07D487/04

摘要： This invention provides a pyrroloazepine compound represented by the following formula (I) or (II): ##STR1## wherein Z.sub.1, Z.sub.2, R, A and Y are defined in the claims. The pyrroloazepine compounds according to the present invention are drugs having excellent anti-serotonin action. Coupled with their high safety, they can therefore be used as novel therapeutics for ischemic heart diseases. In addition, the compounds of the present invention include those having anti-.alpha..sub.1 action. Such compounds are effective as hypotensive drugs. Pyrroloazepine compounds according to the present invention are therefore extremely useful as therapeutics for a wide variety of circulatory diseases.

摘要翻译： PCT No.PCT / JP92 / 01009 Sec。 371日期：1993年4月7日 102（e）日期1993年4月7日PCT提交1992年8月6日PCT公布。 公开号WO93 / 03032 日本特开昭通1 9 9 3年2月18日。本发明提供由下式（I）或（II）表示的吡咯并氮杂化合物：其中Z1，Z2，R，A和Y定义 在权利要求中。 根据本发明的吡咯并氮吡啶化合物是具有优异的抗5-羟色胺作用的药物。 结合高安全性，因此可用作缺血性心脏病的新疗法。 此外，本发明的化合物包括具有抗α1作用的化合物。 这些化合物作为降压药有效。 因此，根据本发明的吡罗洛西泮化合物作为多种循环系统疾病的治疗剂非常有用。

公开(公告)号：US06288056B1

公开(公告)日：2001-09-11

申请号：US09673514

申请日：2000-10-17

申请人： Atsuto Ogata ,  Norio Inomata ,  Akira Mizuno

发明人： Atsuto Ogata ,  Norio Inomata ,  Akira Mizuno

IPC分类号： A61K3155

CPC分类号： A61K31/55 ,  A61K31/496

摘要： A method of treating or improving intermittent claudication, which comprises administering, to a patient with intermittent claudication, a pyrroloazepine derivative or a pharmacologically acceptable salt thereof, said pyrroloazepine derivative being represented by the following formula (I): wherein the dotted line indicates existence or nonexistence of a bond; when the bond of the dotted line exists, X does not exist, and, when the bond of the dotted line does not exist, X represents a hydrogen atom, a hydroxy group or a group OR1 in which R1 represents a substituted or unsubstituted alkyl group; Y represents a linear or branched, substituted or unsubstituted alkyl group; Z1 and Z2 are the same or different and each independently represent a hydrogen atom, a hydroxy group or a halogen atom; and W represents a hydrogen atom or a methyl group.

摘要翻译： 一种治疗或改善间歇性跛行的方法，其包括对间歇性跛行的患者施用吡咯并氮衍生物或其药理学上可接受的盐，所述吡咯并氮衍生物由下式（I）表示：其中虚线表示存在或 不存在债券; 当存在虚线的键时，X不存在，并且当虚线的键不存在时，X表示氢原子，羟基或其中R 1表示取代或未取代的烷基的基团OR 1 ; Y表示直链或支链的取代或未取代的烷基; Z 1和Z 2相同或不同，各自独立地表示氢原子，羟基或卤素原子; W表示氢原子或甲基。

公开(公告)号：US07892486B2

公开(公告)日：2011-02-22

申请号：US10594387

申请日：2005-03-29

申请人： Akira Mizuno ,  Hiroyuki Yuyama ,  Yoshinori Shirahara

发明人： Akira Mizuno ,  Hiroyuki Yuyama ,  Yoshinori Shirahara

IPC分类号： A61L2/20

CPC分类号： A61L2/208 ,  A61L2/14 ,  A61L2/202 ,  A61L2202/24

摘要： A harmless sterilization method and sterilization apparatus which provide adequate sterilization effects without residual gas. The method includes a sterilization step in which a chamber containing an object to be sterilized is depressurized; a hydrogen peroxide supply step in which hydrogen peroxide is supplied into the chamber; an ozone supply step in which ozone is supplied into the chamber; a sterilization step in which the hydrogen peroxide and ozone supplied inside the chamber are dispersed to sterilize the object to be sterilized; an exhaust step in which gas inside the chamber is exhausted; and a plasma generation step in which plasma is generated inside the chamber to break down hydrogen peroxide and ozone remaining near the object to be sterilized, and radicals which promote sterilization are generated.

摘要翻译： 无残留气体提供充分杀菌效果的无害灭菌方法和杀菌装置。 该方法包括灭菌步骤，其中包含待消毒物体的室被减压; 过氧化氢供给步骤，其中将过氧化氢供给到室中; 将臭氧供给到所述室内的臭氧供给步骤; 灭菌步骤，其中分散在室内的过氧化氢和臭氧被分散以消毒待消毒的物体; 废气步骤，其中室内的气体被耗尽; 以及等离子体产生步骤，其中在腔室内产生等离子体以分解残留在待消毒物体附近的过氧化氢和臭氧，并产生促进灭菌的自由基。

公开(公告)号：US07758675B2

公开(公告)日：2010-07-20

申请号：US11587816

申请日：2005-04-13

申请人： Kenta Naito ,  Satoru Senbayashi ,  Yuichi Hamada ,  Akira Mizuno ,  Junichi Kasai ,  Yoshinobu Tamura

发明人： Kenta Naito ,  Satoru Senbayashi ,  Yuichi Hamada ,  Akira Mizuno ,  Junichi Kasai ,  Yoshinobu Tamura

IPC分类号： B03C3/15

CPC分类号： F01N3/01 ,  B01D53/32 ,  B01D2258/01 ,  B01D2259/818 ,  B03C3/36 ,  B03C3/45 ,  B03C2201/30 ,  F01N2240/20 ,  Y02T10/20 ,  Y10S55/38

摘要： Gas treatment equipment including a corona electrode and a dust-collection electrode facing the corona electrode, and forming corona discharge in gas passing between the corona electrode and the dust-collection electrode by applying a high voltage between them to collect components in the gas wherein a gas turbulence accelerator is located in the vicinity of the surface of the dust-collection electrode facing the corona electrode.

摘要翻译： 气体处理设备包括电晕电极和面向电晕电极的集尘电极，并且通过在它们之间施加高电压而在电晕电极和集尘电极之间形成的气体中形成电晕放电，以收集气体中的成分，其中 气体湍流加速器位于集尘电极的面对电晕电极的表面附近。

公开(公告)号：US07187098B2

公开(公告)日：2007-03-06

申请号：US11065176

申请日：2005-02-24

申请人： Masahiro Hasebe ,  Masami Ishikawa ,  Akira Mizuno

发明人： Masahiro Hasebe ,  Masami Ishikawa ,  Akira Mizuno

IPC分类号： H02K21/12

CPC分类号： H02K21/24 ,  H02K1/2793

摘要： An axial gap rotating electrical machine is provided with permanent magnets and cores in a rotor. The permanent magnets are oriented such that magnetization surfaces face in the circumferential direction of the rotor. The cores are arranged alternately with the permanent magnets in the circumferential direction of the rotor. The amount of magnetic flux on the outside in the radial direction of the rotor is made greater than the amount of magnetic flux on the inside in the radial direction of the rotor. As a result, the magnetic flux density at the rotor cores can be made substantially constant in the radial direction of the rotor and torque output with respect to the size of the permanent magnets is improved by preventing magnetic saturation of the cores.

摘要翻译： 轴向间隙旋转电机在转子中设置永磁体和铁心。 永磁体被定向为使得磁化表面在转子的圆周方向上面对。 芯与转子的圆周方向上的永久磁铁交替排列。 使转子的径向外侧的磁通量大于转子径向内侧的磁通量。 结果，转子芯的磁通密度可以在转子的径向方向上基本上恒定，并且通过防止磁芯的磁饱和来改善相对于永磁体的尺寸的扭矩输出。

公开(公告)号：US20060197721A1

公开(公告)日：2006-09-07

申请号：US10548717

申请日：2004-05-27

申请人： Akira Mizuno ,  Masayuki Esaki

发明人： Akira Mizuno ,  Masayuki Esaki

IPC分类号： G09G3/28

CPC分类号： H04N5/64 ,  H04N5/70 ,  Y10S345/901

摘要： A flat panel image display unit such as a plasma display device is provided having a structure of signal input terminals that is adaptable flexibly to a plurality of different kinds of video signals. The image display unit includes a flat display panel, a display drive circuit block, an input signal circuit block connected between the display drive circuit block and an external apparatus for outputting a video signal, and an enclosure for housing the above components. The input signal circuit block includes a plurality of different kinds of board blocks provided replaceably according to a plurality of different forms of signals. A casing member is placed inside the enclosure and is provided with an insertion opening for accepting insertion of any of the board blocks. A guide rail is for positioning the board block to a predetermined position. The plurality of guide rails are provided according to the board block of a smallest unit size.

摘要翻译： 提供了诸如等离子体显示装置的平板图像显示单元，其具有可灵活地适应于多种不同种类的视频信号的信号输入端的结构。 图像显示单元包括平面显示面板，显示驱动电路块，连接在显示驱动电路块和用于输出视频信号的外部设备之间的输入信号电路块，以及用于容纳上述组件的外壳。 输入信号电路块包括根据多种不同形式的信号可替换地提供的多种不同种类的板块。 外壳部件放置在外壳的内部，并且设置有用于接受任何板块的插入的插入开口。 导轨用于将板块定位到预定位置。 根据最小单位尺寸的板块提供多个导轨。

公开(公告)号：US20050179337A1

公开(公告)日：2005-08-18

申请号：US10983894

申请日：2004-11-09

申请人： Masahiro Hasebe ,  Masami Ishikawa ,  Akira Mizuno ,  Yoji Takeda ,  Masayuki Sanada

发明人： Masahiro Hasebe ,  Masami Ishikawa ,  Akira Mizuno ,  Yoji Takeda ,  Masayuki Sanada

IPC分类号： H02K1/12 ,  H02K1/27 ,  H02K16/02 ,  H02K19/10 ,  H02K21/24 ,  H02K21/12 ,  H02K1/22 ,  H02K3/00

CPC分类号： H02K21/24 ,  H02K1/2793 ,  H02K19/103

摘要： An axial gap electric rotary machine includes a rotor and a stator which face each other with an axial gap therebetween. The rotor includes permanent magnets which are arranged with their magnetic poles spaced around the circumference of the rotor, with the magnetic poles of adjacent permanent magnets being opposite each other. The permanent magnets and rotor cores are alternately arranged around the circumference of the rotor. Consequently, north poles and south poles are alternately formed at a surface of the rotor facing the stator, and reluctance of a magnetic path which passes through a permanent magnet is larger than reluctance of a magnetic path which does not pass through the permanent magnet, whereby the functions of a reluctance type rotary machine and a permanent magnet synchronous machine are combined in a compact structure.

摘要翻译： 轴向间隙电动旋转机械包括转子和定子，它们之间具有轴向间隙。 转子包括永磁体，它们的磁极间隔绕转子的周边排列，相邻的永磁体的磁极彼此相对。 永久磁铁和转子铁芯绕转子周围交替布置。 因此，北极和南极交替地形成在面向定子的转子的表面，并且穿过永磁体的磁路的磁阻大于不通过永磁体的磁路的磁阻，由此 磁阻式旋转机和永磁同步电机的功能结合在一起，结构紧凑。

公开(公告)号：US06838522B2

公开(公告)日：2005-01-04

申请号：US09973902

申请日：2001-10-11

申请人： Mikio Hashimoto ,  Takasi Ueda ,  Masaaki Kawasaki ,  Satoru Moriya ,  Akira Mizuno ,  Daisuke Fukuoka ,  Junichi Imuta ,  Keiji Hirose ,  Junji Saito ,  Yoshihisa Kiso

发明人： Mikio Hashimoto ,  Takasi Ueda ,  Masaaki Kawasaki ,  Satoru Moriya ,  Akira Mizuno ,  Daisuke Fukuoka ,  Junichi Imuta ,  Keiji Hirose ,  Junji Saito ,  Yoshihisa Kiso

IPC分类号： C08F4/642 ,  C08L23/08 ,  C08L23/10 ,  C08L23/12 ,  C08L23/14 ,  C08L23/16 ,  C08L23/04

CPC分类号： C08L23/12 ,  C08L23/0815 ,  C08L23/10 ,  C08L23/142 ,  C08L23/16 ,  C08L2205/02 ,  C08L2314/06 ,  C08L2666/04

摘要： A propylene polymer composition comprising a propylene polymer prepared by using a zirconocene catalyst having two aryl-substituted indenyl group and having a melt flow rate (MFR) of 0.01 to 30 g/10 min and a second propylene polymer prepared by using a zirconocene catalyst having a melt flow rate (MFR) of 30 to 1,000 g/10 min and, if desired, a soft polymer, a ratio of the MFR of the second propylene polymer to the MFR of the second propylene polymer being not less than 30. These propylene polymer compositions are excellent in heat resistance, mechanical strength, tensile elongation at break, etc., and hence they can be favorably used for various structural materials such as those of automobile and electrical appliances, daily necessaries, various films and sheets.

摘要翻译： 一种丙烯聚合物组合物，其包含通过使用具有两个芳基取代的茚基的熔体流动速率（MFR）为0.01至30g / 10min的二茂锆催化剂制备的丙烯聚合物，以及通过使用二茂锆催化剂制备的第二丙烯聚合物，所述二茂锆催化剂具有 熔体流动速率（MFR）为30至1,000g / 10min，如果需要，软质聚合物，第二丙烯聚合物的MFR与第二丙烯聚合物的MFR之比不小于30.这些丙烯 聚合物组合物的耐热性，机械强度，断裂伸长率等优异，因此可以有利地用于汽车，电器，日用品，各种膜，片等各种结构材料。

公开(公告)号：US5397780A

公开(公告)日：1995-03-14

申请号：US30268

申请日：1993-04-06

申请人： Akira Mizuno ,  Hidetsura Cho ,  Mikiko Miya ,  Toshio Tatsuoka ,  Takafumi Ishihara

发明人： Akira Mizuno ,  Hidetsura Cho ,  Mikiko Miya ,  Toshio Tatsuoka ,  Takafumi Ishihara

IPC分类号： C07D487/04 ,  A61K31/55

CPC分类号： C07D487/04

摘要： This invention provides a pyrroloazepine derivative represented by the following formula (I): ##STR1## where the substituents are defined in the specification. The pyrroloazepine derivatives according to the present invention are drugs having excellent anti-.alpha..sub.1 action and anti-serotonin action and feature high safety. They can therefore be used, for example, as novel therapeutics for circulatory diseases.

摘要翻译： PCT No.PCT / JP92 / 01008 Sec。 371日期：1993年4月6日 102（e）日期1993年4月6日PCT提交1992年8月6日PCT公布。 出版物WO87 / 07274 日本1987年12月3日。本发明提供由下式（I）表示的吡咯并氮衍生物：在说明书中。 根据本发明的吡咯并氮衍生物是具有优异的抗α1作用和抗5-羟色胺作用并且具有高安全性的药物。 因此，它们可以用作例如循环系统疾病的新疗法。

公开(公告)号：US5223434A

公开(公告)日：1993-06-29

申请号：US790357

申请日：1991-11-12

申请人： Iwao Kanno ,  Matsutaro Murakami ,  Yohjiro Toda ,  Tadasu Sugawara ,  Masahiko Handa ,  Akira Mizuno

发明人： Iwao Kanno ,  Matsutaro Murakami ,  Yohjiro Toda ,  Tadasu Sugawara ,  Masahiko Handa ,  Akira Mizuno

IPC分类号： G21G1/10

CPC分类号： A61M5/1407 ,  A61M5/36 ,  G21G1/10 ,  A61M2205/051 ,  Y10S422/903 ,  Y10S436/813 ,  Y10T436/13

摘要： An apparatus for producing and automatically injecting H.sub.2.sup.15 O, having: a target box adapted to be irradiated with a deuteron beam, a gas supplying device for supplying a hydrogen gas and a nitrogen gas as raw-material gases to the target box a radioactive-isotope conveying pipe connecting the target box and a vacuum pump for maintaining the interior of the target box and the interior of the radioactive-isotope conveying pipe in a vacuum state. In addition, the apparatus has an injection-fluid producing device and an automatic injection device, wherein the target box, the injection-fluid producing device and the automatic injection device are fluidly communicated with one another.

摘要翻译： 一种用于制造和自动注入H215O的装置，具有：适于被氘核束照射的靶盒，用于将氢气和氮气作为原料气体供应给靶盒的气体供给装置，放射性同位素输送 连接目标箱和真空泵的管道，用于将目标箱的内部和放射性同位素输送管的内部保持在真空状态。 此外，该装置具有注射液生成装置和自动注射装置，其中，目标盒，注射流体产生装置和自动注射装置彼此流体连通。