Planographic printing plate precursor and stack thereof
    21.
    发明申请
    Planographic printing plate precursor and stack thereof 有权
    平版印刷版前体及其叠层

    公开(公告)号:US20070231740A1

    公开(公告)日:2007-10-04

    申请号:US11730411

    申请日:2007-04-02

    IPC分类号: G03C1/00

    摘要: The present invention provides a planographic printing plate precursor, including: a support; and a photosensitive layer containing a polymerizable compound; an oxygen barrier layer; and a protective layer containing a filler (preferably an organic resin particle), the layers being formed in this order on the support. The present invention also provides a stack of planographic printing plate precursors, produced by stacking the planographic printing plate precursors with the photosensitive layer side outermost layer and the support side rear surface of the adjacent plate precursor in direct contact with each other.

    摘要翻译: 本发明提供一种平版印刷版原版,包括:载体; 和含有可聚合化合物的感光层; 氧阻隔层; 和含有填料(优选有机树脂颗粒)的保护层,这些层依次形成在载体上。 本发明还提供了通过将平版印刷版前体与感光层侧最外层和邻近的板前体的支撑侧后表面彼此直接接触而堆叠制成的平版印刷版前体的叠层。

    Sugar ester derivatives, reagents for measurement of hydrolase activity
and methods for measurement of hydrolase activity
    22.
    发明授权
    Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity 失效
    糖酯衍生物,水解酶活性测定试剂和水解酶活性测定方法

    公开(公告)号:US6162614A

    公开(公告)日:2000-12-19

    申请号:US975167

    申请日:1992-11-12

    IPC分类号: C07H15/203 C12Q1/34 C12Q1/44

    摘要: A sugar ester derivative of the general formula (I) ##STR1## wherein G stands for a group of the formula (A) ##STR2## or a group of the formula (B) ##STR3## wherein .lambda. means 0 or 1; at least one of R.sub.1 and R.sub.2 means an ester residue of a saturated or unsaturated fatty acid having 1-30 carbon atoms and the other group means hydrogen atom or acetyl group, and R.sub.3 means a group of the formula (C) ##STR4## wherein X means a halogen atom, m means an integer of 0 to 4, Y means hydroxy group, an alkoxy group, a carboxyl group or sulfonic acid group, n means 0 or 1 and Z means nitro group or nitrovinyl group and its use.The sugar ester derivative of the general formula (I) is useful as a substrate for the measurement of lipase or esterase activities, and the reagents and the methods for measuring lipase or esterase activities which comprise said sugar ester derivative as the substrate are excellent in terms of reproducibility and sensitivity and enable the measurement of lipase or esterase activities in accordance with rate-assay method by an easy procedure.

    摘要翻译: 通式(I)的糖酯衍生物,其中G表示式(A)的基团或式(B)的基团,其中λ表示0或1; R 1和R 2中的至少一个表示具有1-30个碳原子的饱和或不饱和脂肪酸的酯残基,另一个基团是指氢原子或乙酰基,R 3表示式(C)的基团,其中X表示 卤素原子,m表示0〜4的整数,Y表示羟基,烷氧基,羧基或磺酸基,n表示0或1,Z表示硝基或硝基乙烯基及其用途。 通式(I)的糖酯衍生物可用作测定脂肪酶或酯酶活性的底物,并且包含所述糖酯衍生物作为底物的试剂和测定脂肪酶或酯酶活性的方法是优异的 的重现性和灵敏度,并且能够通过简单的方法根据速率测定方法测量脂肪酶或酯酶活性。

    Antiviral agent
    24.
    发明授权
    Antiviral agent 失效
    抗病毒剂

    公开(公告)号:US4174407A

    公开(公告)日:1979-11-13

    申请号:US869144

    申请日:1978-01-13

    IPC分类号: A61K31/13

    CPC分类号: A61K31/13

    摘要: Viral infections caused by viruses belonging to Herpes and Influenza groups can be controlled by administering an effective amount of 3-amino-4-homoisotwistane of the formula, ##STR1##

    摘要翻译: 可以通过施用有效量的下式的3-氨基-4-异亮氨酸来控制属于疱疹和流感组的病毒引起的病毒感染

    N-substituted heterocyclic derivatives and preparation thereof
    25.
    发明授权
    N-substituted heterocyclic derivatives and preparation thereof 失效
    N-取代的杂环衍生物及其制备

    公开(公告)号:US4080328A

    公开(公告)日:1978-03-21

    申请号:US484274

    申请日:1974-06-28

    IPC分类号: C07D401/04

    摘要: Novel N-substituted heterocyclic derivatives represented by the formula, ##STR1## wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen, nitro, trifluoromethyl, amino or N-lower alkanoylamino; R.sub.2 is hydrogen, halogen, amino or N-lower alkanoylamino; W is oxygen, sulfur, sulfinyl or sulfonyl; and Y is ##STR2## (wherein R.sub.3 is hydrogen, lower alkyl or lower alkanoyl; and R.sub.4 is hydrogen, halogen or lower alkyl), and pharmaceutically acceptable salts thereof, which have excellent anti-inflammatory, analgesic, sedative, anti-convulsive or anti-hypertensive activities.

    摘要翻译: 由下式表示的新型N-取代的杂环衍生物,其中R是氢或低级烷酰基; R 1是氢,低级烷基,低级烷氧基,卤素,硝基,三氟甲基,氨基或N-低级烷酰基氨基; R2是氢,卤素,氨基或N-低级烷酰氨基; W是氧,硫,亚磺酰基或磺酰基; (其中R3为氢,低级烷基或低级烷酰基,R4为氢,卤素或低级烷基)及其药学上可接受的盐,其具有优异的抗炎,止痛,镇静作用 ,抗惊厥或抗高血压活动。

    N-(.omega.-Amino)alkylaniline derivatives
    27.
    发明授权
    N-(.omega.-Amino)alkylaniline derivatives 失效
    N - ({107 - 氨基)烷基苯胺衍生物

    公开(公告)号:US4017624A

    公开(公告)日:1977-04-12

    申请号:US603240

    申请日:1975-08-08

    CPC分类号: C07D211/52 C07D295/12

    摘要: An N-(.omega.-amino)alkylaniline derivative of the formula: ##STR1## and its pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## with a compound of the formula:H--A[wherein R is hydrogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkanoyl or aroyl, R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkoxy,A is ##STR3## (wherein R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkoxy or trifluoromethyl), ##STR4## (wherein R.sub.2 is as defined above and R.sub.3 is hydrogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkanoyl), ##STR5## (wherein R.sub.2 is as defined above or ##STR6## (wherein R.sub.2 and R.sub.3 are each as defined above) and n is 2, 3 or 4].

    摘要翻译: 下式的N-(ω-氨基)烷基苯胺衍生物及其药学上可接受的盐,其可用作抗精神病药,并且可以通过使下式化合物与下式化合物反应来制备:< IMAGE> :

    Preparation of 2-benzoylalkylbenzomorphan
    30.
    发明授权
    Preparation of 2-benzoylalkylbenzomorphan 失效
    2-苯甲酰基烷基苯并咪唑的制备

    公开(公告)号:US3953441A

    公开(公告)日:1976-04-27

    申请号:US150841

    申请日:1971-06-07

    IPC分类号: C07D211/70 C07D221/26

    CPC分类号: C07D221/26 C07D211/70

    摘要: A novel process for preparing 2-benzoylalkylbenzomorphan derivatives and salts thereof, represented by the formula ##SPC1##Wherein n, R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification. The process comprises reacting a pyridinium derivative of the formula, ##SPC2##Wherein X is a halogen atom and Y' is an ethylenedioxy group; with a Grignard reagent of the formula, ##SPC3##Wherein R' is a hydrogen atom or a C.sub.1 -C.sub.3 alkoxy group and Z is a halogen atom, to yield a 1,2-dihydropyridine derivative of the formula; ##SPC4##And then reducing the said 1,2-dihydropyridine derivative to give a 1,2,5,6-tetrahydropyridine derivative of the formula, ##SPC5##Wherein Y is an oxygen atom or an ethylenedioxy group, and further cyclizing the obtained 1,2,5,6-tetrahydropyridine derivative.

    摘要翻译: 由式WHEREIN N,R,R1,R2,R3和R4表示的用于制备2-苯甲酰基烷基苯并喃衍生物及其盐的新方法如本说明书中所定义。 该方法包括使下式的吡啶鎓衍生物WHEREIN X是卤素原子,Y'是亚乙二氧基; 与下式的格利雅试剂,其中R'是氢原子或C1-C3烷氧基,Z是卤素原子,得到下式的1,2-二氢吡啶衍生物; 然后减少所得的1,2-二氢吡啶衍生物,得到本发明的1,2,5,6-四氢吡啶衍生物,其中Y是氧原子或亚乙二氧基,进一步环化得到的1,2,5,6-四氢吡啶衍生物, 6-四氢吡啶衍生物。