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公开(公告)号：US07831311B2
公开(公告)日：2010-11-09
申请号：US11119416
申请日：2005-04-29
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body is sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. The lead body may include a variety of features that reduce the axial stiffness of the lead without significantly impacting the operation and structural integrity of lead components, such as electrodes, conductors and insulators.
摘要翻译： 可植入引线具有引线本体结构，其设计用于在患者移动期间适应施加在引线本体上的负载力。 引线体具有足够的拉伸能力以抵抗否则会导致引线故障，电极的轴向迁移，锚固损坏或组织损伤的力。 引线体可以包括减少引线的轴向刚度的各种特征，而不会显着地影响诸如电极，导体和绝缘体的引线部件的操作和结构完整性。
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公开(公告)号：US07519432B2
公开(公告)日：2009-04-14
申请号：US11119389
申请日：2005-04-29
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body may be sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. Increasing stretchability of a lead body can also increase the vulnerability of the lead body to flex fatigue, buckling fatigue, kinking, and crush. Therefore, the lead described herein includes a reinforcement to create a lead body that is resistant to flex fatigue, buckling fatigue, kinking and crush.
摘要翻译： 可植入引线具有引线本体结构，其设计用于在患者移动期间适应施加在引线本体上的负载力。 引线体可以是足够的可拉伸的以抵抗否则会导致引线故障，电极的轴向迁移，锚固损伤或组织损伤的力。 引线体的增加拉伸性也可以增加引线体疲劳疲劳，弯曲疲劳，扭结和挤压的脆弱性。 因此，本文所述的导线包括增强以产生耐挠曲疲劳，弯曲疲劳，扭结和挤压的引线体。
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公开(公告)号：US07174219B2
公开(公告)日：2007-02-06
申请号：US10981092
申请日：2004-11-03
申请人： Carl D. Wahlstrand , Thomas Barry Hoegh , Gregory A. Hrdlicka , Thomas E. Cross, Jr. , James M. Olsen
发明人： Carl D. Wahlstrand , Thomas Barry Hoegh , Gregory A. Hrdlicka , Thomas E. Cross, Jr. , James M. Olsen
IPC分类号： A61N1/05
CPC分类号： A61N1/0529 , A61N1/05 , A61N1/0534 , A61N1/0553 , A61N1/06 , A61N1/086 , A61N1/3718
摘要： A pulse stimulation system configured for implantation into a patient's body comprises a pulse stimulator, a conductive stimulation lead having a proximal end electrically coupled to the pulse simulator and having a distal end, and an electrode assembly coupled to the distal end of the stimulation lead. The electrode assembly comprises an electrode body having a therapy electrode thereon that is electrically coupled to the stimulation lead for delivering therapy to the patient. A floating electrode is configured to contact the patient's body tissue and has a surface area substantially larger than that of the therapy electrode. A filter is coupled between the therapy electrode and the floating electrode for diverting RF energy toward the floating electrode and away from the therapy electrode.
摘要翻译： 构造成用于植入患者体内的脉冲刺激系统包括脉冲刺激器，具有电耦合到脉冲模拟器的近端的导电刺激引线，并且具有远端，以及耦合到刺激引线的远端的电极组件。 电极组件包括其上具有治疗电极的电极体，其电耦合到刺激引线以将治疗递送给患者。 浮动电极被配置为接触患者的身体组织，并且其表面积基本上大于治疗电极的表面积。 过滤器耦合在治疗电极和浮动电极之间，用于将RF能量朝向浮动电极转移并远离治疗电极。
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公开(公告)号：US5354326A
公开(公告)日：1994-10-11
申请号：US9607
申请日：1993-01-27
申请人： Richard H. Comben , Barry J. Grant , Michael D. Serfling , Thomas E. Cross, Jr. , David J. Stanton
发明人： Richard H. Comben , Barry J. Grant , Michael D. Serfling , Thomas E. Cross, Jr. , David J. Stanton
CPC分类号： H01R24/58 , A61N1/37 , H01R11/18 , H01R13/24 , H01R13/6392 , H01R2201/12
摘要： A connector for establishing an external connection with multiple-conductor implantable leads. The connector body is generally cylindrical in shape and includes a unique twist lock design. The cylindrical connector body has two sections which rotate axially with respect to one another, from an `open` position to a `closed` position. Each of the sections has a longitudinal slot therein extending along its surface parallel to the cylindrical axis of the connector. In the `open` position, the slots in the respective sections are in alignment, forming a single longitudinal opening. The opening is keyed to accept an elongated end piece from a lead stylet, the end piece being attached to the end of the implantable electrode. The end piece supports the end of the lead such that the multiple, spaced apart electrical contacts disposed on the lead are exposed on at least one side. The cylindrical body has similarly spaced apart contacts disposed therein, such that when the stylet end piece is placed into the longitudinal opening in the connector, the contacts on the supported lead are brought into contact with the corresponding contacts disposed within the connector body. The end piece is secured inside the connector body by twisting the sections of the connector body into their `closed` position, so that the respective sets of spaced apart contacts are held in firm contact with each other. As the sections of the cylindrical connector body are twisted into the `closed` position, a downward pressure is exerted mechanically on the end piece to ensure good electrical contact.
摘要翻译： 用于建立与多导体可植入引线的外部连接的连接器。 连接器主体通常为圆柱形，并且包括独特的扭锁设计。 圆柱形连接器主体具有两个相对于彼此轴向旋转的部分，从“打开”位置到“关闭”位置。 每个部分具有沿其平行于连接器的圆柱形轴线的表面延伸的纵向狭槽。 在“打开”位置，相应部分中的槽对准，形成单个纵向开口。 该开口用于接纳来自引线探针的细长端部件，该端部件附接到可植入电极的端部。 端件支撑引线的端部，使得设置在引线上的多个间隔开的电触头暴露在至少一侧上。 圆柱体具有设置在其中的类似间隔开的触头，使得当探针端部件被放置在连接器中的纵向开口中时，被支撑的引线上的触点与布置在连接器主体内的相应触点相接触。 通过将连接器主体的部分扭转到它们的“关闭”位置，将端件固定在连接器主体内，使得各组间隔开的触点保持彼此牢固接触。 当圆柱形连接器主体的部分被扭曲到“关闭”位置时，机械地向端部件施加向下的压力，以确保良好的电接触。
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公开(公告)号：US08620435B2
公开(公告)日：2013-12-31
申请号：US11450133
申请日：2006-06-09
申请人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Jeffrey S. Evanson , Kenneth T. Heruth , Paul W. Wacnik
发明人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Jeffrey S. Evanson , Kenneth T. Heruth , Paul W. Wacnik
IPC分类号： A61N1/34
CPC分类号： A61N1/36021 , A61M5/14 , A61M5/142 , A61M2205/054 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/0558 , A61N1/36017 , A61N1/36071 , A61N1/37211 , A61N1/375
摘要： Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
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26.发明授权公开(公告)号：US08588914B2
公开(公告)日：2013-11-19
申请号：US11450127
申请日：2006-06-09
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/0504 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/3756
摘要： An implantable medical device (IMD) with a housing and electrodes on at least two surfaces of the housing is described. The surfaces may be, for example, opposed, substantially parallel surfaces, e.g., top and bottom surfaces. Location of electrodes on multiple surfaces of the housing may allow the IMD to deliver stimulation to a variety of tissues and with a variety of current field configurations. For example, the IMD may deliver peripheral nerve field stimulation (PNFS) to one or more tissue areas via electrodes selected from one or both of the surfaces to, for example, reduce the sensation of pain in a tissue area proximate to an implantation site of the IMD without targeting a specific nerve. The IMD may be implanted between or within intra-dermal, deep dermal, or subcutaneous layers of the tissue of the patient to deliver PNFS to any one or more of these layers.
摘要翻译： 描述了在壳体的至少两个表面上具有壳体和电极的可植入医疗装置（IMD）。 表面可以是例如相对的基本上平行的表面，例如顶部和底部表面。 电极在壳体的多个表面上的位置可以允许IMD将刺激递送到各种组织以及各种当前的现场配置。 例如，IMD可以通过选自一个或两个表面的电极将外周神经区域刺激（PNFS）递送到一个或多个组织区域，以例如减少接近植入部位的组织区域中的疼痛感觉 IMD没有针对特定的神经。 IMD可以植入在患者组织的真皮内，深层皮肤或皮下层之间或内，以将PNFS递送到这些层中的任何一个或多个层。
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公开(公告)号：US08116880B2
公开(公告)日：2012-02-14
申请号：US12367664
申请日：2009-02-09
申请人： Thomas E. Cross, Jr.
发明人： Thomas E. Cross, Jr.
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/0558
摘要： A medical lead for electrical stimulation or sensing. The medical lead has a generally flat paddle on the distal end of the lead body. An electrode array is provided on the paddle, with the electrode array displaced along the length of the paddle toward the distal end. Advantages include allowing the electrode array may be advanced into position for electrical stimulation or sensing with the flat paddle extending through connective tissue, such as the ligamentum flavum, thus facilitating repositioning, withdrawal or explanting the medical lead, as well as using the flat features of the paddle to anchor the lead to the connective tissue.
摘要翻译： 用于电刺激或感测的医疗导线。 医用引线在引线主体的远端具有大致平坦的焊盘。 电极阵列设置在桨上，电极阵列沿桨的长度朝向远端移位。 优点包括允许电极阵列可以推进到用于电刺激或通过延伸穿过结缔组织（例如黄韧带）的扁平桨进行感测，从而便于重新定位，撤出或移除医用引线，以及使用 桨将锚导向结缔组织。
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公开(公告)号：US07844344B2
公开(公告)日：2010-11-30
申请号：US10993195
申请日：2004-11-18
申请人： Carl D. Wahlstrand , Gregory A. Hrdlicka , Thomas E. Cross, Jr. , Thomas Barry Hoegh , James M. Olsen , Stephen L. Bolea
发明人： Carl D. Wahlstrand , Gregory A. Hrdlicka , Thomas E. Cross, Jr. , Thomas Barry Hoegh , James M. Olsen , Stephen L. Bolea
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0553 , A61N1/086
摘要： A stimulation lead to be implanted into a patient's body includes at least one distal stimulation electrode and at least one conductive filer electrically coupled to the distal stimulation electrode. A jacket houses the conductive filer and provides a path distributed along at least a portion of the length of the lead for conducting induced RF energy from the filer to the patient's body.
摘要翻译： 将被植入患者体内的刺激导体包括至少一个远端刺激电极和至少一个与远侧刺激电极耦合的导电滤波器。 护套安装导电滤波器并且提供沿着引线长度的至少一部分分布的路径，以将感应的RF能量从滤波器传导到患者身体。
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29.发明授权公开(公告)号：US07761170B2
公开(公告)日：2010-07-20
申请号：US11118076
申请日：2005-04-29
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body may be sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. Increasing stretchability of a lead body can also increase the vulnerability of the lead body to flex fatigue, buckling fatigue, kinking, and crush. Therefore, the lead described herein includes conductors that comprise coiled wires positioned substantially parallel to a center axis of the lead. The conductors described herein may be coiled around fibers that limit the axial stiffness of the coiled wires to ensure full recovery from axial loading.
摘要翻译： 可植入引线具有引线本体结构，其设计用于在患者移动期间适应施加在引线本体上的负载力。 引线体可以是足够的可拉伸的以抵抗否则会导致引线故障，电极的轴向迁移，锚固损伤或组织损伤的力。 引线体的增加拉伸性也可以增加引线体疲劳疲劳，弯曲疲劳，扭结和挤压的脆弱性。 因此，本文所述的引线包括导体，其包括基本上平行于引线的中心轴定位的线圈导线。 本文所述的导体可围绕纤维缠绕，从而限制线圈线的轴向刚度，以确保从轴向负载完全恢复。
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公开(公告)号：US06210417B1
公开(公告)日：2001-04-03
申请号：US09302085
申请日：1999-04-29
IPC分类号： A61M532
CPC分类号： A61N1/0539 , A61B5/6864
摘要： There is disclosed a medical apparatus for positioning and anchoring a lead to a cranium burr hole. The apparatus comprises generally a sleeve and a plurality of springs positioned within the sleeve. The apparatus may be inserted within a conventional burr hole ring or serve as a stand-alone anchoring device that fits within a burr hole. Once a lead is inserted into the sleeve between the plurality of springs, the springs exert a radial force on the lead body, thereby holding the lead in the desired position. The apparatus may also include a circular disc, defining a slot, mountable within the burr hole ring. The circular disc permits the selective positioning of the lead within the burr hole.
摘要翻译： 公开了用于将引线定位和固定到头颅钻孔的医疗装置。 该装置通常包括套筒和定位在套筒内的多个弹簧。 该装置可以插入传统的钻孔环中，或用作安装在钻孔内的独立锚定装置。 一旦将引线插入到多个弹簧中的套筒中，弹簧在引线主体上施加径向力，从而将引线保持在期望的位置。 该装置还可以包括圆盘，其限定可安装在钻孔环内的槽。 圆盘允许将引线选择性地定位在钻孔内。
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