摘要:
A method of making a molecularly imprinted porous structure makes use of a surfactant analog of the molecule to be imprinted that has the imprint molecule portion serving as the surfactant headgroup. The surfactant analog is allowed to self-assemble in a mixture to create at least one supramolecular structure having exposed imprint groups. The imprinted porous structure is formed by adding reactive monomers to the mixture and allowing the monomers to polymerize, with the supramolecular structure serving as a template. The resulting solid structure has a shape that is complementary to the shape of the supramolecular structure and has cavities that are the mirror image of the imprint group. Similarly, molecularly imprinted particles may be made by using the surfactant to create a water-in-oil microemulsion wherein the imprint groups are exposed to the water phase. When reactive monomers are allowed to polymerize in the water phase to form particles, the surface of the particles have cavities that are the mirror image of the imprint group.
摘要:
A method of making a molecularly imprinted porous structure makes use of a surfactant analog of the molecule to be imprinted that has the imprint molecule portion serving as the surfactant headgroup. The surfactant analog is allowed to self-assemble in a mixture to create at least one supramolecular structure having exposed imprint groups. The imprinted porous structure is formed by adding reactive monomers to the mixture and allowing the monomers to polymerize, with the supramolecular structure serving as a template. The resulting solid structure has a shape that is complementary to the shape of the supramolecular structure and has cavities that are the mirror image of the imprint group. Similarly, molecularly imprinted particles may be made by using the surfactant to create a water-in-oil microemulsion wherein the imprint groups are exposed to the water phase. When reactive monomers are allowed to polymerize in the water phase to form particles, the surface of the particles have cavities that are the mirror image of the imprint group.
摘要:
An immobilized substrate surface is chemically modified by manipulating annzyme which is immobilized to a solid surface. Modifications include (1) chemical dissection of a substrate surface such as by chemical hydrolysis, (2) chemical synthesis on a substrate surface, and (3) chemical patterning of a substrate surface. The enzyme may be coupled to colloidal beads or particles, locally flat solid surfaces including planar, textured planar, cylindrical and spherical surfaces or arbitrary predefined shapes, or scanning probe microscope probes. In the patterning applications, colloidal particles containing the enzyme can be confined to desired regions of the substrate surface by various techniques which control the movement of the particles. The particles can be confined to tunnels or channels in a patterned polymer mold on top of the substrate surface. The enzyme can also be immobilized onto the surface of a raised pattern and this patterned surface can then be placed in contact with the immobilized substrate.
摘要:
An operating mechanism for an enclosure-mounted circuit breaker includes a slider for engaging the circuit breaker handle; a shaft-driven pivot for moving the slider between the handle on, off and reset positions; a holder for holding the slider in its reset position; a base plate for supporting the pivot and the slider; and a door-mounted rotary handle for rotating the shaft and operating the pivot. The rotary handle may engage the shaft in the on and off positions, and may be detached from the shaft in the reset position. The pivot may include a first pivot arm having a first cam surface for holding the slider in its reset position. A second cam surface on a second pivot arm may engage a first slider surface from off to on; a second slider surface from on to off, from off toward reset, and to resist reset to off; and an oblique slider surface when adjacent reset. The second cam surface may disengage the oblique surface at reset. Alternatively, the slider may include a notch and the base plate may include a latch for engaging the notch. The pivot may include a single pivot arm having a cam surface which engages a slider surface from off to on; an oblique slider surface from on to off, and from off to reset in order to engage the notch and the latch; and another oblique surface to disengage the notch and the latch from reset to off. The slider may include an oblique shoulder for moving the handle from on to off and from off to reset, for resisting the handle force from reset to off, and for using the handle force to engage the notch and the latch in the reset position in order to substantially decouple the handle force from the rotary handle.
摘要:
A positive off mechanism for a circuit breaker includes a pair of positive off levers slideable in slots in the side plates and extendable into the path of the operating handle to prevent movement of the handle to the off position when the contacts are welded closed. The positive off levers are actuated by positive off links pivotally mounted to the side plates and coupled to the positive off levers by "dog bone" connections. The positive off links in turn are actuated by the toggle mechanism of the circuit breaker which collapses to open the contacts during normal circuit breaker operation, but which remains erect when the contacts are welded closed.
摘要:
The invention provides silicone hydrogel contact lenses that exhibit reduced back surface debris and reduced incidence of superior epithelial arcurate lesions.
摘要:
The invention provides silicone hydrogel contact lenses that exhibit reduced back surface debris and reduced incidence of superior epithelial arcurate lesions.