公开(公告)号：US20200061587A1

公开(公告)日：2020-02-27

申请号：US16609528

申请日：2018-05-01

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Roman GOY ,  Jonathan Alan MEDLOCK

IPC: B01J23/745 ,  B01J23/755 ,  B01J23/75 ,  B01J23/28 ,  B01J23/26 ,  B01J37/02 ,  B01J23/10 ,  B01J23/44

Abstract: The present invention is related to a new metal powder catalytic system (catalyst), its production and its use in hydrogenation processes.

公开(公告)号：US20170305827A1

公开(公告)日：2017-10-26

申请号：US15518355

申请日：2015-10-15

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Thomas NETSCHER ,  Jan SCHUETZ ,  Bettina WUESTENBERG

IPC: C07C45/51 ,  C07C11/12 ,  C07C47/225 ,  C07C5/23 ,  C07C2601/16

CPC classification number: C07C45/512 ,  C07C5/23 ,  C07C11/12 ,  C07C29/42 ,  C07C47/225 ,  C07C2523/46 ,  C07C2527/14 ,  C07C2601/16 ,  C07C33/14

Abstract: The present invention relates to an improved method for producing specific α, β-unsaturated aldehydes.

公开(公告)号：US20240059650A1

公开(公告)日：2024-02-22

申请号：US18256992

申请日：2021-12-13

Applicant: DSM IP ASSETS B.V. ,  UNIVERSITÄT BASEL

Inventor： Werner BONRATH ,  Thomas BUCHHOLZ ,  Thomas NETSCHER ,  Jan SCHUETZ ,  Christof SPARR

IPC: C07C407/00

CPC classification number: C07C407/00 ,  C07C2601/16

Abstract: The present invention relates to the photooxidation of 2,4,6-trimethyl-phenol to yield 4-hydroperoxy-2,4,6-trimethylcyclohexa-2,5-dien-1-one using methylene blue as photosensitizer in a solvent mixture of water and alcohols using light of the high wavelength range of the visible spectrum. This process allows 5 obtaining 4-hydroxy-2,4,6-trimethylcyclohexa-2,5-dien-1-one and 2,3,5-trimethyl-hydroquinone in high yields and selectivity from 2,4,6-trimethylphenol.

公开(公告)号：US20230144339A1

公开(公告)日：2023-05-11

申请号：US17802682

申请日：2021-03-01

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Roman GOY ,  Marcel JORAY

IPC: C07C41/54 ,  C07C41/58

CPC classification number: C07C41/54 ,  C07C41/58

Abstract: The present invention is directed to a process for the manufacture of 1,1,4,4-tetramethoxy-2-butene from 2,5-dimethoxy-2,5-dihydrofuran with methanol in the presence of an acidic ion exchanger as catalyst, whereby the molar ratio of 2,5-dimethoxy-2,5-dihydrofuran to methanol is ≥1:45. The present invention is further directed to a process of separating 1,1,4,4-tetramethoxy-2-butene, methanol and 2,5-dimethoxy-2,5-dihydrofuran from each other and H2O whereby a basic compound, preferably a basic metal salt or a basic ion exchanger, is present. Both processes can be carried out on an industrial scale, batch-wise or in continuous mode and are sustainable since the selectivity and the space-time-yields are high and less waste compared to known processes is produced. Further objects of the present invention are the use of a basic compound in the distillation of a mixture comprising H2O, 1,1,4,4-tetramethoxy-2-butene and 2,5-dimethoxy-2,5-dihydrofuran, as well as the use of an acidic ion exchanger as catalyst in a reaction of 2,5-dimethoxy-2,5-dihydrofuran with methanol to 1,1,4,4-tetramethoxy-2-butene, whereby the molar ratio of 2,5-dimethoxy-2,5-dihydrofuran to methanol is ≥1:45.

公开(公告)号：US20230125156A1

公开(公告)日：2023-04-27

申请号：US17915453

申请日：2021-03-22

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Marc-André MUELLER ,  Bettina WUESTENBERG ,  Viktor ZIMMERMANN

IPC: C07C67/08 ,  C07C69/28

Abstract: The present invention relates to a new process for the production of vitamin A and/or its derivatives.

公开(公告)号：US20230090098A1

公开(公告)日：2023-03-23

申请号：US17787806

申请日：2020-12-15

Applicant: DSM IP Assets B.V.

Inventor： Werner BONRATH ,  Marc-André MUELLER ,  Bettina WUESTENBERG

IPC: C07F7/18

Abstract: The present invention relates to the functionalisation of specific 1,3-alpha-dienes. These functionalized 1,3-alpha-dienes are important intermediates in organic synthe-sis (especially in the synthesis of carotenoids, vitamin A and/or vitamin A derivatives).

公开(公告)号：US20220234974A1

公开(公告)日：2022-07-28

申请号：US17613732

申请日：2020-05-26

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Jonathan Alan MEDLOCK

IPC: C07C29/17 ,  C07C33/16 ,  C07C33/14 ,  B01J23/44 ,  B01J27/232 ,  B01J35/00

Abstract: The present invention relates to a process of hydrogenating an alkynol selectively to an alkenol by hydrogen using a hydrogenation catalyst which is palladium supported on a carrier in the presence of an additive which is an organic phosphorus compound bearing either a phosphine or a phosphine oxide group and with the proviso that if the additive bears a phosphino group that the additive bears two or more phosphino groups.

公开(公告)号：US20220220071A1

公开(公告)日：2022-07-14

申请号：US17603488

申请日：2020-04-03

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Marc-André MUELLER ,  Bettina WUESTENBERG ,  Florian ZIEGLER

IPC: C07C403/12

Abstract: The present invention relates to new specific enol esters of formula (I) as well as to a process for their production by acylation of the corresponding dihydroretinal analogue. In formula (I) R is —COR′ where R′ is a C1-C16 alkyl group.

公开(公告)号：US20220169590A1

公开(公告)日：2022-06-02

申请号：US17676077

申请日：2022-02-18

Applicant: DSM IP ASSETS B.V.

Inventor： Raphael BEUMER ,  Werner BONRATH ,  Marc-André MUELLER ,  Bettina WÜESTENBERG

IPC: C07C67/293

Abstract: Processes for synthesizing new compounds that may usefully be employed in organic synthesis, especially in the synthesis of vitamin A or β-carotene and derivatives thereof, e.g. canthaxanthin, astaxanthin or zeaxanthin are disclosed. The new compounds are especially useful as intermediates (building blocks) in the synthesis of vitamin A or β-carotene, preferably vitamin A.

公开(公告)号：US20220024960A1

公开(公告)日：2022-01-27

申请号：US17414029

申请日：2019-12-17

Applicant: DSM IP Assets B.V.

Inventor： Werner BONRATH ,  Rolf KUENZI

IPC: C07H3/02 ,  C07H1/00 ,  B01J31/02

Abstract: The present invention relates to an improved process to produce a specific and very efficient epoxidation-catalyst (1,2:4,5-Di-O-isopropylidene-β-D-erythro-2,3-hexodiulo-2,6-pyranose).