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31 条记录 (耗时 0.025 秒)

    Methods for photometric analysis
    22.
    发明授权
    Methods for photometric analysis 失效
    光度分析方法

    公开(公告)号：US5478750A

    公开(公告)日：1995-12-26

    申请号：US292558

    申请日：1994-08-18

    申请人： Daniel M. Bernstein ,  Paul J. Lingane ,  Robert Nagle ,  Vladimir E. Ostoich

    发明人： Daniel M. Bernstein ,  Paul J. Lingane ,  Robert Nagle ,  Vladimir E. Ostoich

    IPC分类号： G01N21/07 ,  G01N21/25 ,  G01N21/17

    CPC分类号： G01N21/07 ,  G01N21/255 ,  G01N2201/0415 ,  Y10T436/10

    摘要： The present invention provides a compact, highly automated photometric analyzer for measuring the concentration of substances found in a fluid, typically a blood sample or other body fluid sample taken from a patient. The operator places a small quantity of the sample into a special rotor and then loads the rotor into the analyzer. The analyzer accepts the rotor, centrifuges and dilutes the sample, and distributes the sample into a plurality of cuvettes near the outer edge of the rotor. Some of these cuvettes hold reagents which react with the sample. The analyzer then measures light absorption within the sample at a number of preselected frequencies. According to the present invention, a pair of specially designed apertures direct light from the sample through a plurality of beam splitters, interference filters, and associated photodetectors. The system also includes means for performing automatic calibration and error checking functions. These means include a through hole through the rotor, and an opaque body carried by the rotor. Additionally, measurements may be repeated through a given cuvette and the results averaged to minimize the effect of random variations between measurements.

    摘要翻译： 本发明提供了一种紧凑的，高度自动化的光度分析仪，用于测量从流体（通常是从患者获取的血液样本或其他体液样品）中发现的物质的浓度。 操作者将少量样品放入专用转子中，然后将转子装入分析仪。 分析仪接受转子，离心并稀释样品，并将样品分配到转子外边缘附近的多个比色皿中。 其中一些比色皿含有与样品反应的试剂。 然后分析仪以多个预选频率测量样品内的光吸收。 根据本发明，一对特别设计的孔径通过多个分束器，干涉滤光器和相关联的光电检测器引导来自样品的光。 该系统还包括用于执行自动校准和错误检查功能的装置。 这些装置包括通过转子的通孔和由转子承载的不透明体。 此外，可以通过给定的比色杯重复测量，并且平均结果以最小化测量之间的随机变化的影响。

    Analyte Monitoring Devices and Methods
    25.
    发明申请
    Analyte Monitoring Devices and Methods 有权
    分析物监测装置和方法

    公开(公告)号：US20140148665A1

    公开(公告)日：2014-05-29

    申请号：US13877543

    申请日：2011-12-13

    申请人： Daniel M. Bernstein

    发明人： Daniel M. Bernstein

    IPC分类号： A61B5/1473 ,  A61B5/00 ,  A61B5/145

    CPC分类号： A61B5/1477 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/6833 ,  A61B2560/0214 ,  A61B2560/0252

    摘要： On-body units are provided and include a transcutaneous analyte sensor, electronic circuitry electrically coupled to the sensor, and an on-body housing having electrical contacts disposed thereon. The on-body housing comprises a substantially flat surface and a curved and convex surface opposite the substantially flat surface. Systems and methods including the on-body units are also provided. Methods for performing continuity measurements using on-body units are also provided. The methods include positioning an on-body unit (OBU) on a skin of a subject, contacting a continuity test instrument to the OBU; and performing a continuity measurement with the continuity test instrument. An AC signal may be provided across two electrical contacts, or a DC signal may be provided across two electrical contacts in opposite directions for the same amount of time. The measurement may be performed with one electrical contact, or with isolated electrical contacts.

    摘要翻译： 提供体内单元并且包括经皮分析物传感器，电耦合到传感器的电子电路，以及设置在其上的电触点的体内壳体。 本体外壳包括基本平坦的表面和与基本上平坦的表面相对的弯曲和凸起的表面。 还提供了包括身体单位的系统和方法。 还提供了使用身体单位执行连续性测量的方法。 所述方法包括将身体单元（OBU）定位在受试者的皮肤上，将连续性测试仪器接触到OBU; 并使用连续性测试仪进行连续性测量。 可以在两个电触点之间提供交流信号，或者可以在相同的时间量内在两个电触头上以相反方向提供DC信号。 测量可以用一个电触点或隔离的电触点进行。

    Systems and methods for distributing fluids
    30.
    发明授权
    Systems and methods for distributing fluids 失效
    用于分配流体的系统和方法

    公开(公告)号：US5803105A

    公开(公告)日：1998-09-08

    申请号：US804708

    申请日：1997-02-21

    申请人： Jim Wasson ,  Steve Miller ,  Peter Wright ,  Daniel M. Bernstein

    发明人： Jim Wasson ,  Steve Miller ,  Peter Wright ,  Daniel M. Bernstein

    IPC分类号： B01J4/00 ,  B01J4/02 ,  B01J19/00 ,  C40B60/14 ,  F16K7/14 ,  F16K11/22 ,  F16K11/24 ,  F16K27/00

    CPC分类号： F16K27/003 ,  B01J19/0046 ,  F16K11/22 ,  F16K11/24 ,  F16K7/14 ,  B01J2219/00286 ,  B01J2219/00398 ,  C40B60/14 ,  Y10T137/0318 ,  Y10T137/7761 ,  Y10T137/8158 ,  Y10T137/87249 ,  Y10T137/87684

    摘要： A valve apparatus (2) for selectively distributing the sequential passage of separate, organic fluids to a common receiver, such as a reaction vessel. The valve apparatus comprises a valve body member (16) having multiple openings (56) and a plurality of separate conduits (54) each communicating a fluid source with one of the openings. The body member also has a common passage (60) with circular groove portions (62) surrounding the openings so that fluid flows radially outward from the openings toward the common passage. A plurality of pistons (30) are individually reciprocable between first and second positions for controlling fluid flow between associated openings and the common passage. The invention also provides a system (100) and method for measuring and delivering a precise quantity of each of the organic fluids, e.g., chemical reagents, to the reaction vessel.

    摘要翻译： 一种阀装置（2），用于选择性地将单独的有机流体的顺序通道分配到诸如反应容器的公共接收器。 阀装置包括具有多个开口（56）的阀体构件（16）和多个分开的管道（54），每个管道将流体源与其中一个开口连通。 主体构件还具有围绕开口的圆形槽部分（62）的公共通道（60），使得流体从开口朝向公共通道径向向外流动。 多个活塞（30）在第一和第二位置之间单独往复运动，用于控制相关联的开口和公共通道之间的流体流动。 本发明还提供了一种系统（100）和用于测量并将精确量的每种有机流体例如化学试剂输送到反应容器的方法。