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    Analyte monitoring devices and methods
    2.
    发明授权
    Analyte monitoring devices and methods 有权
    分析物监测装置及方法

    公开(公告)号：US09339229B2

    公开(公告)日：2016-05-17

    申请号：US13877543

    申请日：2011-12-13

    申请人： Daniel M. Bernstein

    发明人： Daniel M. Bernstein

    IPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/1473

    CPC分类号： A61B5/1477 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/6833 ,  A61B2560/0214 ,  A61B2560/0252

    摘要： On-body units are provided and include a transcutaneous analyte sensor, electronic circuitry electrically coupled to the sensor, and an on-body housing having electrical contacts disposed thereon. The on-body housing comprises a substantially flat surface and a curved and convex surface opposite the substantially flat surface. Systems and methods including the on-body units are also provided. Methods for performing continuity measurements using on-body units are also provided. The methods include positioning an on-body unit (OBU) on a skin of a subject, contacting a continuity test instrument to the OBU; and performing a continuity measurement with the continuity test instrument. An AC signal may be provided across two electrical contacts, or a DC signal may be provided across two electrical contacts in opposite directions for the same amount of time. The measurement may be performed with one electrical contact, or with isolated electrical contacts.

    摘要翻译： 提供体内单元并且包括经皮分析物传感器，电耦合到传感器的电子电路，以及设置在其上的电触点的体内壳体。 本体外壳包括基本平坦的表面和与基本上平坦的表面相对的弯曲和凸起的表面。 还提供了包括身体单位的系统和方法。 还提供了使用身体单位执行连续性测量的方法。 所述方法包括将身体单元（OBU）定位在受试者的皮肤上，将连续性测试仪器接触到OBU; 并使用连续性测试仪进行连续性测量。 可以在两个电触点之间提供交流信号，或者可以在相同的时间量内在两个电触头上以相反方向提供DC信号。 测量可以用一个电触点或隔离的电触点进行。

    Methods for photometric analysis
    5.
    发明授权
    Methods for photometric analysis 失效
    光度分析方法

    公开(公告)号：US5478750A

    公开(公告)日：1995-12-26

    申请号：US292558

    申请日：1994-08-18

    申请人： Daniel M. Bernstein ,  Paul J. Lingane ,  Robert Nagle ,  Vladimir E. Ostoich

    发明人： Daniel M. Bernstein ,  Paul J. Lingane ,  Robert Nagle ,  Vladimir E. Ostoich

    IPC分类号： G01N21/07 ,  G01N21/25 ,  G01N21/17

    CPC分类号： G01N21/07 ,  G01N21/255 ,  G01N2201/0415 ,  Y10T436/10

    摘要： The present invention provides a compact, highly automated photometric analyzer for measuring the concentration of substances found in a fluid, typically a blood sample or other body fluid sample taken from a patient. The operator places a small quantity of the sample into a special rotor and then loads the rotor into the analyzer. The analyzer accepts the rotor, centrifuges and dilutes the sample, and distributes the sample into a plurality of cuvettes near the outer edge of the rotor. Some of these cuvettes hold reagents which react with the sample. The analyzer then measures light absorption within the sample at a number of preselected frequencies. According to the present invention, a pair of specially designed apertures direct light from the sample through a plurality of beam splitters, interference filters, and associated photodetectors. The system also includes means for performing automatic calibration and error checking functions. These means include a through hole through the rotor, and an opaque body carried by the rotor. Additionally, measurements may be repeated through a given cuvette and the results averaged to minimize the effect of random variations between measurements.

    摘要翻译： 本发明提供了一种紧凑的，高度自动化的光度分析仪，用于测量从流体（通常是从患者获取的血液样本或其他体液样品）中发现的物质的浓度。 操作者将少量样品放入专用转子中，然后将转子装入分析仪。 分析仪接受转子，离心并稀释样品，并将样品分配到转子外边缘附近的多个比色皿中。 其中一些比色皿含有与样品反应的试剂。 然后分析仪以多个预选频率测量样品内的光吸收。 根据本发明，一对特别设计的孔径通过多个分束器，干涉滤光器和相关联的光电检测器引导来自样品的光。 该系统还包括用于执行自动校准和错误检查功能的装置。 这些装置包括通过转子的通孔和由转子承载的不透明体。 此外，可以通过给定的比色杯重复测量，并且平均结果以最小化测量之间的随机变化的影响。