Method, system, and apparatus for cardiovascular signal analysis, modeling, and monitoring
    27.
    发明授权
    Method, system, and apparatus for cardiovascular signal analysis, modeling, and monitoring 有权
    用于心血管信号分析,建模和监测的方法,系统和装置

    公开(公告)号:US08057398B2

    公开(公告)日:2011-11-15

    申请号:US12200995

    申请日:2008-08-29

    IPC分类号: A61B5/02

    摘要: Disclosed embodiments of the invention include a method, system, and apparatus to monitor cardiovascular signals such as arterial blood pressure (ABP), pulse oximetry (POX), and intracranial pressure (ICP).The system can be used to calculate and monitor useful clinical information such as heart rate, respiratory rate, pulse pressure variation (PPV), harmonic phases, pulse morphology, and for artifact removal. The method uses a statistical state-space model of cardiovascular signals and a generalized Kalman filter (EKF) to simultaneously estimate and track the cardiovascular parameters of interest such as the cardiac fundamental frequency and higher harmonics, respiratory fundamental frequency and higher harmonics, cardiac component harmonic amplitudes and phases, respiratory component harmonic amplitudes and phases, and PPV.

    摘要翻译: 本发明的公开的实施例包括监测诸如动脉血压(ABP),脉搏血氧饱和度(POX)和颅内压(ICP)的心血管信号的方法,系统和装置。 该系统可用于计算和监测有用的临床信息,如心率,呼吸频率,脉搏压力变化(PPV),谐波相位,脉冲形态和人为因素去除。 该方法使用心血管信号的统计状态空间模型和广义卡尔曼滤波器(EKF)来同时估计和跟踪感兴趣的心血管参数,例如心脏基频和高次谐波,呼吸基频和高次谐波,心脏分量谐波 振幅和相位,呼吸分量谐波幅度和相位以及PPV。

    Method and Apparatus for Assessment of Fluid Responsiveness
    29.
    发明申请
    Method and Apparatus for Assessment of Fluid Responsiveness 有权
    流体响应性评估方法与装置

    公开(公告)号:US20110077532A1

    公开(公告)日:2011-03-31

    申请号:US12891795

    申请日:2010-09-27

    IPC分类号: A61B5/021 A61B5/02

    摘要: Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal.

    摘要翻译: 公开了用于从心血管压力信号(包括动脉血压(ABP))和光电体积描记信号确定心脏参数的方法和装置,以量化由呼吸引起的幅度调制程度并预测流体反应性。 公开的实施例包括用于评估在具有一个或多个处理器的数字计算机中实现的流体响应性的方法,包括:(a)测量心血管信号,以及(b)使用非线性状态空间计算预测来自所述心血管信号的流体响应性的动态指数 估计。 根据一个特定实施例,非限制性地,非线性状态空间估计器基于诸如动脉血压或体积描记信号的心血管信号的模型,并且使用边缘化的粒子滤波器来估计预测流体响应性的动态指数,其基本上 相当于所述心血管信号的脉压的变化。

    Circulation monitoring system and method
    30.
    发明授权
    Circulation monitoring system and method 有权
    循环监测系统及方法

    公开(公告)号:US07628760B2

    公开(公告)日:2009-12-08

    申请号:US12001505

    申请日:2007-12-11

    IPC分类号: A61B5/02 A61B5/00

    摘要: A lightweight portable probe or transducer containing a transmissive or reflective electro-optical emitter and receptor in the infrared spectrum is fitted on a subject's finger or toe. Associated electronics energize and monitor the probe, detect cardio-rhythmic fluctuations therefrom, and process digital data over a prescribed window to produce a non-invasive, qualitative or quantitative measure of the subject's circulation. In accordance with one embodiment of the invention, a simple tri-color LED array is used to indicate the subject's circulation as being normal, reduced, or borderline.

    摘要翻译: 在红外光谱中包含透射或反射电光发射器和受体的轻便便携式探头或传感器安装在受试者的手指或脚趾上。 相关电子设备激励和监测探针,检测心跳节奏的波动,并在规定的窗口处理数字数据,以产生对受试者循环的非侵入性,定性或定量的测量。 根据本发明的一个实施例,简单的三色LED阵列用于指示受试者的循环是正常的,减少的或边界的。