公开(公告)号：US20120124478A1

公开(公告)日：2012-05-17

申请号：US13264502

申请日：2010-04-15

Applicant: Tony Richard King ,  David Cole

Inventor： Tony Richard King ,  David Cole

IPC: G06F3/048

CPC classification number: G06F16/90

Abstract: A metadata browse system supports the capture of metadata from multiple sources and formats, its conversion to a standard format, the linking of concepts from disconnected namespaces, discovery of hidden information, and the display of this data.

Abstract translation: 元数据浏览系统支持从多个源和格式捕获元数据，将其转换为标准格式，从断开的命名空间链接概念，发现隐藏信息以及显示此数据。

公开(公告)号：US20110192881A1

公开(公告)日：2011-08-11

申请号：US13089216

申请日：2011-04-18

Applicant: Daniel J. Balbierz ,  Pablo R. Hambly ,  Jason S. Stewart ,  David Cole

Inventor： Daniel J. Balbierz ,  Pablo R. Hambly ,  Jason S. Stewart ,  David Cole

IPC: A61B17/068 ,  A61B17/072

CPC classification number: A61B17/068 ,  A61B17/072 ,  A61B17/07207 ,  A61B17/115 ,  A61B2017/07214 ,  A61B2017/07228 ,  A61B2017/07271 ,  A61F5/0086

Abstract: A staple housing includes an array of staples each in a staple delivery position or “ready position” ready to be fired into target tissue. A staple driver is advanceable to drive the ready-position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.

Abstract translation: 订书钉壳体包括各自位于钉送出位置的订书钉阵列或准备好被烧制到目标组织中的“就绪位置”。 订书钉驱动器可前进，以使用订书钉推动器将订书钉从订书钉驱动到组织中。 在使用期间，准备位置中的订书钉使用订书钉推动器同时被烧制到目标组织中，从而在目标组织中形成一排钉。 在阵列被点火之后，钉仓壳体内的一个或多个进给机构将第二组订书钉从一个或多个订书钉存储位置推进到就绪位置，以准备第二组钉的点火。

公开(公告)号：US20100311179A1

公开(公告)日：2010-12-09

申请号：US12477421

申请日：2009-06-03

Applicant: Sarah Coulter ,  Gregory van Buskirk ,  Sumi Cate ,  Kenneth Vieira ,  Rebecca Brauch ,  David Cole

Inventor： Sarah Coulter ,  Gregory van Buskirk ,  Sumi Cate ,  Kenneth Vieira ,  Rebecca Brauch ,  David Cole

IPC: G01N33/00 ,  H01J49/26 ,  G01T1/20

CPC classification number: C11D11/007 ,  C11D17/00 ,  Y10T436/204998 ,  Y10T436/212

Abstract: The present invention relates to a method for measuring the percentage natural of a cleaning composition using radiocarbon dating data. The percentage natural of a cleaning composition is defined as the amount of material that comes from non-petroleum based or derived products. By using radiocarbon data for the entire composition or its individual components one can determine the percentage of materials which are from non-petroleum based or derived products, and calculate the percent Renewable Carbon Index (RCI). The percent RCI can be used to calculate the percent natural of the cleaning composition as defined by the methods of the present invention.

Abstract translation: 本发明涉及使用放射性碳测年数据测量清洁组合物的天然百分比的方法。 清洁组合物的天然百分比定义为来自非石油基或衍生产物的材料的量。 通过使用整个组合物或其各个组分的放射性碳数据，可以确定来自非石油基或衍生产物的材料的百分比，并计算可再生碳指数（RCI）百分比。 可以使用RCI百分比来计算由本发明的方法定义的清洁组合物的天然百分比。

公开(公告)号：US07721932B2

公开(公告)日：2010-05-25

申请号：US12052874

申请日：2008-03-21

Applicant: David Cole ,  Andrew Smith

Inventor： David Cole ,  Andrew Smith

IPC: A61B17/068

CPC classification number: A61B17/072 ,  A61B17/064 ,  A61B17/115 ,  A61B17/32053 ,  A61B2017/00539 ,  A61B2017/00818 ,  A61B2017/07271 ,  A61B2017/306 ,  A61F5/0013 ,  A61F5/0083

Abstract: Described herein are endoscopic staplers used to apply one or more fasteners to body tissue. In one embodiment, a fastener-applying device, which is preferably a stapler, is passed transorally into the stomach and used to plicate stomach tissue by engaging tissue from inside of the stomach and drawing it inwardly. In the disclosed embodiments, the tissue is drawn inwardly into a vacuum chamber, causing sections of serosal tissue on the exterior of the stomach to be positioned facing one another. The disclosed staplers allow the opposed sections of tissue to be moved into contact with one another, and preferably deliver staples for maintaining contact between the tissue sections at least until serosal bonds form between them. Each of these steps may be performed wholly from the inside of the stomach and thus can eliminate the need for any surgical or laparoscopic intervention. After one or more plications are formed, medical devices may optionally be coupled to the plication(s) for retention within the stomach.

Abstract translation: 这里描述的是用于将一个或多个紧固件应用于身体组织的内窥镜吻合器。 在一个实施例中，优选为吻合器的紧固件施加装置通过经腹部通入胃中，并用于通过从胃内部接合组织并将其向内抽吸来摧毁胃组织。 在所公开的实施例中，将组织向内拉入真空室，使得胃外部的浆膜组织的部分彼此相对定位。 所公开的订书机允许组织的相对部分彼此接触，并且优选地递送用于维持组织部分之间的接触的钉，至少在它们之间形成浆膜粘结。 这些步骤中的每一个可以完全从胃内进行，因此可以消除对任何手术或腹腔镜干预的需要。 在形成一个或多个脓肿之后，医疗装置可以可选地耦合到脓肿以保持在胃内。

公开(公告)号：US07503930B2

公开(公告)日：2009-03-17

申请号：US11707331

申请日：2007-02-16

Applicant: Adam Sharkawy ,  Mark Foley ,  Darin Gittings ,  David Cole ,  Sam Crews

Inventor： Adam Sharkawy ,  Mark Foley ,  Darin Gittings ,  David Cole ,  Sam Crews

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2210/009 ,  A61F2220/0016 ,  A61F2220/0066 ,  A61F2230/0054 ,  A61F2250/006

Abstract: Implantable prosthetic valve systems and methods for implanting them are provided. Magnets are employed within one or more components of the valve systems to facilitate anchoring of the prosthetic valve at a target implant site, delivery of the prosthetic valve to the target implant site or both.

Abstract translation: 提供了植入式假体瓣膜系统及其植入方法。 磁体被用在阀系统的一个或多个部件内，以便于在目标植入部位处将人工瓣膜锚固，将人造瓣膜递送到目标植入部位或两者。

公开(公告)号：US20070256634A1

公开(公告)日：2007-11-08

申请号：US11806622

申请日：2007-06-01

Applicant: Allen Simpson ,  Richard Smith ,  Marcia Wright ,  Phillip Johnson ,  David Cole

Inventor： Allen Simpson ,  Richard Smith ,  Marcia Wright ,  Phillip Johnson ,  David Cole

IPC: B05C3/00

CPC classification number: F16D69/02 ,  B05D1/18 ,  B05D1/32 ,  B05D3/042 ,  F16D2250/0038

Abstract: Mask (10, 10′, 21, 22, 30) for use in coating a carbon-carbon composite brake disc (25) with anti-oxidant. The mask is composed of carbon-carbon composite material or nonreactive ceramic material. The mask is configured with edge ridges (11, 13, 34, 36) that are aligned with the outer and inner annular diameters of the carbon-carbon composite brake disc, a gas flow channel (12, 32) between the ridges, and a gas access port (18, 40) that allows gas to enter the gas flow channel. The mask may also include a gas exit port (16) having a valve (17) operatively connected thereto, so that gas flow may be restricted when pressure within the mask and carbon-carbon composite brake disc falls below a specified minimum value. Also, a method of avoiding application of liquid antioxidant material to a friction surface of a carbon-carbon composite brake disc, by: covering the friction surface with a mask configured to deliver compressed gas to the friction surface, and directing compressed gas across the friction surface and through pores in the carbon-carbon composite brake disc and/or in the mask while the masked brake disc is in the presence of the antioxidant material in a liquid state.

Abstract translation: 面罩（10,10'，21,22,30），用于用抗氧化剂涂覆碳 - 碳复合制动盘（25）。 掩模由碳 - 碳复合材料或非反应性陶瓷材料组成。 掩模配置有与碳 - 碳复合制动盘的外部和内部环形直径对准的边缘脊（11,13,34,36），脊之间的气体流动通道（12,32）和 气体进入口（18,40），其允许气体进入气体流动通道。 掩模还可以包括具有可操作地连接到其上的阀（17）的气体出口（16），使得当掩模和碳 - 碳复合制动盘内的压力低于规定的最小值时，可能限制气流。 另外，通过以下方式，避免将液体抗氧化剂应用于碳 - 碳复合制动盘的摩擦面上：用配置成将压缩气体输送到摩擦面的掩模覆盖摩擦面，以及将压缩气体导向摩擦 在碳 - 碳复合制动盘和/或掩模中的表面和通孔，同时掩蔽的制动盘在处于液态的抗氧化剂材料的存在下。

公开(公告)号：US20070197581A1

公开(公告)日：2007-08-23

申请号：US11654821

申请日：2007-01-18

Applicant: Theodros Asberom ,  Thomas Bara ,  Chad Bennett ,  Duane Burnett ,  Mary Ann Caplen ,  John Clader ,  David Cole ,  Martin Domalski ,  Hubert Josien ,  Chad Knutson ,  Hongmei Li ,  Mark McBriar ,  Dmitri Pissarnitski ,  Li Qiang ,  Murali Rajagopalan ,  Thavalakulamgara Sasikumar ,  Jing Su ,  Haiqun Tang ,  Wen-Lian Wu ,  Ruo Xu ,  Zhiqiang Zhao

Inventor： Theodros Asberom ,  Thomas Bara ,  Chad Bennett ,  Duane Burnett ,  Mary Ann Caplen ,  John Clader ,  David Cole ,  Martin Domalski ,  Hubert Josien ,  Chad Knutson ,  Hongmei Li ,  Mark McBriar ,  Dmitri Pissarnitski ,  Li Qiang ,  Murali Rajagopalan ,  Thavalakulamgara Sasikumar ,  Jing Su ,  Haiqun Tang ,  Wen-Lian Wu ,  Ruo Xu ,  Zhiqiang Zhao

IPC: A61K31/4741 ,  A61K31/473 ,  A61K31/353 ,  A61K31/19

CPC classification number: C07D311/22 ,  C07C317/14 ,  C07C317/20 ,  C07C317/44 ,  C07C2602/08 ,  C07C2602/10 ,  C07C2602/12 ,  C07D311/80 ,  C07D311/92 ,  C07D311/94 ,  C07D313/08 ,  C07D335/06 ,  C07D405/12 ,  C07D409/12 ,  C07D491/04 ,  C07D493/04

Abstract: This invention discloses novel gamma secretase inhibitors of the formula: R2 and R3, or R2 and R4, or R3 and R4, together with the atoms to which they are bound, can form a fused cycloalkyl or fused heterocycloalkyl ring. The cycloalkyl ring or the heterocycloalkyl ring can be optionally substituted with one or more substitutents. One or more compounds of formula (I), or formulations comprising such compounds, may be useful, e.g. in treating Alzheimer's Disease.

Abstract translation: 本发明公开了下式的新型γ分泌酶抑制剂：R 2和R 3，或R 2和R 4 O / >或R 3和R 4与它们所连接的原子一起可以形成稠合的环烷基或稠合的杂环烷基环。 环烷基环或杂环烷基环可任选被一个或多个取代基取代。 一种或多种式（I）化合物或包含这些化合物的制剂可以是有用的，例如， 治疗阿尔茨海默病。

公开(公告)号：US20070193587A1

公开(公告)日：2007-08-23

申请号：US11603753

申请日：2006-11-22

Applicant: Ryan Boucher ,  Joe Paraschac ,  Eric Doelling ,  Edward Gillis ,  David Cole ,  Lionel Nelson

Inventor： Ryan Boucher ,  Joe Paraschac ,  Eric Doelling ,  Edward Gillis ,  David Cole ,  Lionel Nelson

IPC: A61F5/56

CPC classification number: A61F5/56 ,  A61F5/566

Abstract: Systems and methods prevent magnetic implant migration and extrusion in the upper airway. The systems and methods relate both to surgical techniques as well as structural features to address the problem of magnetic implant migration.

Abstract translation: 系统和方法防止上呼吸道中的磁性移植和挤压。 系统和方法涉及外科技术以及结构特征以解决磁性植入物移植的问题。

公开(公告)号：US20070162113A1

公开(公告)日：2007-07-12

申请号：US11707331

申请日：2007-02-16

Applicant: Adam Sharkawy ,  Mark Foley ,  Darin Gittings ,  David Cole ,  Sam Crews

Inventor： Adam Sharkawy ,  Mark Foley ,  Darin Gittings ,  David Cole ,  Sam Crews

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2210/009 ,  A61F2220/0016 ,  A61F2220/0066 ,  A61F2230/0054 ,  A61F2250/006

Abstract: Implantable prosthetic valve systems and methods for implanting them are provided. Magnets are employed within one or more components of the valve systems to facilitate anchoring of the prosthetic valve at a target implant site, delivery of the prosthetic valve to the target implant site or both.

Abstract translation: 提供了植入式假体瓣膜系统及其植入方法。 磁体被用在阀系统的一个或多个部件内，以便于在目标植入部位处将人工瓣膜锚固，将人造瓣膜递送到目标植入部位或两者。

公开(公告)号：US20070048684A1

公开(公告)日：2007-03-01

申请号：US11216679

申请日：2005-08-31

Applicant: David Cole ,  Bradley Barbera

Inventor： David Cole ,  Bradley Barbera

IPC: F23D3/16

CPC classification number: C11C5/008 ,  C11C5/02

Abstract: A candle including regions made up of fuels which produce differing flame heights and/or flame levels when burned, and a method of making such a candle, are disclosed.

Abstract translation: 公开了一种蜡烛，包括燃烧时产生不同火焰高度和/或火焰水平的燃料的区域，以及制造这种蜡烛的方法。