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46 条记录 (耗时 0.045 秒)

    Composition and method for radiation synovectomy of arthritic joints
    21.
    发明授权
    Composition and method for radiation synovectomy of arthritic joints 失效
    关节炎关节放射性滑膜切除术的组成和方法

    公开(公告)号：US5039326A

    公开(公告)日：1991-08-13

    申请号：US408087

    申请日：1989-09-15

    申请人： Delbert E. Day ,  Gary J. Ehrhardt

    发明人： Delbert E. Day ,  Gary J. Ehrhardt

    IPC分类号： A61K9/16 ,  A61K51/12

    CPC分类号： A61K51/1258 ,  A61K9/1611 ,  A61K2121/00

    摘要： A method for preparing nonradioactive microspheres adapted for radiation synovectomy of arthritic joints in a mammal involves forming the microspheres by doping a biodegradable glass material which may be lithium or potassium silicate, lithium or potassium aluminosilicate, lithium or potassium aluminoborate, lithium or potassium germanate or lithium or potassium aluminogermanate with an isotope which may be samarium, holmium, erbium, dysprosium, rhemium or yttrium so that the isotope is chemcially dissolved in and distributed uniformly throughout the glass material. The doped glass material is then treated with an acid wash to produce a thin layer on the surface thereof and heat treated to improve the chemical durability of the glass material by rendering the solubility of the layer lower than that of the underlying glass material.

    摘要翻译： 适用于哺乳动物关节炎关节放射性滑膜切除术的非放射性微球的方法包括通过掺入可生物降解的玻璃材料来形成微球，所述可生物降解的玻璃材料可以是硅酸锂或硅酸钾，铝硅酸锂或钾，铝硼酸锂或钾，锗酸锂或钾， 或具有可能是钐，钬，铒，镝，铼或钇的同位素的铝锗酸钾，使得同位素化学溶解并均匀分布在整个玻璃材料中。 然后将掺杂的玻璃材料用酸洗处理以在其表面上产生薄层并进行热处理，以通过使层的溶解度低于下层玻璃材料的溶解度来改善玻璃材料的化学耐久性。

    Method for preparing porous shells or gels from glass particles
    25.
    发明授权
    Method for preparing porous shells or gels from glass particles 有权
    从玻璃颗粒制备多孔壳或凝胶的方法

    公开(公告)号：US06358531B1

    公开(公告)日：2002-03-19

    申请号：US09241492

    申请日：1999-02-01

    申请人： Delbert E. Day ,  Samuel D. Conzone

    发明人： Delbert E. Day ,  Samuel D. Conzone

    IPC分类号： A61K914

    CPC分类号： A61K9/501 ,  A61K9/1611 ,  C03C1/006 ,  C03C11/002 ,  C03C12/00 ,  Y10S977/775 ,  Y10S977/906

    摘要： A method is provided for preparing shells, concentric shells or porous, homogenous gels from alkali borate glass particles at low temperatures (i.e. room temperature or less than above 100° C.). The alkali borate glass particles contain one or more cations such as aluminum which react with an aqueous solution containing an anion such as hydroxide to form an aqueous insoluble material having a solubility limit of less than about 0.01 wt. percent. The resulting shells or gels may be used in many different applications such as a filler in resins, as filters, precursors for nano-sized powders, as thin surface films or catalyst support media. The resulting shells or gels may also have a chemotherapeutic drug added thereto, following which the resulting product is administered to a mammal and the insoluble material is dissolved form the product in vivo through administration of chelating agent.

    摘要翻译： 提供了一种在低温（即室温或低于100℃）下从碱金属硼酸盐玻璃颗粒制备壳，同心圆壳或多孔同质凝胶的方法。 碱金属硼酸盐玻璃颗粒含有一种或多种阳离子例如铝，其与含有阴离子如氢氧化物的水溶液反应，形成溶解度极限小于约0.01重量％的水不溶性物质。 百分。 所得的壳或凝胶可用于许多不同的应用，例如树脂中的填料，作为过滤器，用于纳米尺寸粉末的前体，作为薄表面膜或催化剂载体介质。 所得的壳或凝胶也可以具有加入其中的化学治疗药物，随后将所得产物施用于哺乳动物，并且通过施用螯合剂在体内将不溶性物质从体内溶解。

    Fiber filled dental porcelain
    26.
    发明授权
    Fiber filled dental porcelain 失效
    纤维填充牙科瓷器

    公开(公告)号：US4793809A

    公开(公告)日：1988-12-27

    申请号：US52843

    申请日：1987-05-21

    申请人： Mark A. Sigler ,  Timothy J. Sigler ,  Delbert E. Day

    发明人： Mark A. Sigler ,  Timothy J. Sigler ,  Delbert E. Day

    IPC分类号： A61K6/06 ,  A61C5/08

    CPC分类号： A61K6/0008 ,  A61K6/0094 ,  A61K6/0215 ,  A61K6/023 ,  A61K6/024 ,  A61K6/0245 ,  A61K6/025

    摘要： Improved dental porcelain compositions and resultant fused porcelain dental restorations are provided which exhibit enhanced strength properties as compared with conventional porcelains. The fiber-filled porcelain compositions of the invention are supplemented with zirconium oxide ceramic fibers in relatively minor amounts of less than 5% by weight. The reinforcing fibers are advantageously predominantly zirconium oxide, and have a relatively short average length of from about 1/32 to 1/4 of an inch. These fibers are normally randomly oriented and homogeneously dispersed throughout the fiber-filled porcelain composition, in order to give a reinforcing fiber network. A completed restoration in accordance with the invention would typically include a core portion formed of the fiber filled porcelain, with the outer portion of the restoration being fabricated from conventional non-fiber reinforced porcelain.

    摘要翻译： 提供改进的牙瓷组合物和所得的熔融牙科修复体，其与传统的瓷器相比表现出增强的强度性能。 本发明的纤维填充瓷组合物以相对少量小于5重量％的氧化锆陶瓷纤维补充。 增强纤维有利地主要是氧化锆，并且具有约1/32至1/4英寸的相对短的平均长度。 这些纤维通常随机取向并均匀地分散在整个纤维填充的瓷组合物中，以便形成增强纤维网。 根据本发明的完成的修复体通常将包括由纤维填充的瓷器形成的芯部分，其中恢复的外部部分由常规的非纤维增强的瓷器制成。

    Chemically durable nitrogen containing phosphate glasses useful for sealing to metals
    27.
    发明授权
    Chemically durable nitrogen containing phosphate glasses useful for sealing to metals 失效
    化学耐用的含氮磷酸盐玻璃，用于密封金属

    公开(公告)号：US4455384A

    公开(公告)日：1984-06-19

    申请号：US447847

    申请日：1982-12-08

    申请人： Delbert E. Day ,  James A. Wilder, Jr.

    发明人： Delbert E. Day ,  James A. Wilder, Jr.

    IPC分类号： C03C3/17 ,  C03C3/21 ,  C03C27/02 ,  C03C3/16

    CPC分类号： C03C3/21 ,  C03C27/02 ,  C03C3/17

    摘要： The chemical durability of alkali phosphate glasses is improved by incorporation of up to 23 weight percent of nitrogen. A typical phosphate glass contains: 10 to 60 mole % of Li.sub.2 O, Na.sub.2 O or K.sub.2 O; 5-40 mole % of BaO or CAO; 0-1 to 10 mole % of Al.sub.2 O.sub.3 ; and 40-70 mole % of P.sub.2 O.sub.5. Nitrides, such as AlN, are the favored additives.

    摘要翻译： 碱性磷酸盐玻璃的化学耐久性通过加入高达23重量％的氮而得到改善。 典型的磷酸盐玻璃含有10〜60摩尔％的Li2O，Na2O或K2O; 5-40摩尔％的BaO或CAO; 0〜10摩尔％的Al 2 O 3; 和40-70摩尔％的P 2 O 5。 氮化物，如AlN，是有利的添加剂。

    Biodegradable Composite Scaffold for Repairing Defects in Load-Bearing Bones
    29.
    发明申请
    Biodegradable Composite Scaffold for Repairing Defects in Load-Bearing Bones 审中-公开
    用于修复承载骨中缺陷的可生物降解复合脚手架

    公开(公告)号：US20140277578A1

    公开(公告)日：2014-09-18

    申请号：US14216451

    申请日：2014-03-17

    申请人： Delbert E. Day ,  Ali Mohammadkhah

    发明人： Delbert E. Day ,  Ali Mohammadkhah

    IPC分类号： A61L27/42

    CPC分类号： A61L27/427 ,  A61L27/34 ,  A61L27/446 ,  A61L27/56 ,  A61L27/58 ,  A61L2430/02

    摘要： A tissue scaffold for repair and regeneration of bone hard tissue or muscle, skin, or organ soft tissue, including load-bearing bone tissue, the scaffold comprising a core of biocompatible, biodegradable inorganic glass fibers; and a biocompatible, biodegradable, flexible polymer film surrounding the core and adhered to the core.

    摘要翻译： 用于修复和再生骨硬组织或肌肉，皮肤或器官软组织（包括承载骨组织）的组织支架，所述支架包含生物相容的可生物降解的无机玻璃纤维芯; 以及围绕芯并且粘附到芯上的生物相容的，可生物降解的柔性聚合物膜。