公开(公告)号：US20080218510A1

公开(公告)日：2008-09-11

申请号：US11997340

申请日：2006-07-12

Applicant: Michael Grass ,  Volker Rasche ,  Dirk Schaefer

Inventor： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

IPC: G06T15/00

CPC classification number: G06T11/005 ,  G06T2211/412

Abstract: A method for generating or reconstruction of three-dimensional (3D) images corresponding to a structure of interest (60) including: acquiring a plurality of image projections corresponding to a structure of interest (60); applying a shape model (66) at a selected 3D seed point (64); and adapting the shape model (66) to represent the structure of interest (60), yielding an adapted shape model. A system for generation and reconstruction of three-dimensional (3D) images. The system (10) includes: an imaging system (12) configured to provide projection data corresponding to a structure of interest (60); and a controller (50) in operable communication with the imaging system (50). The controller (50) is configured to: receive the projection data, (64); apply a shape model (66) at a selected 3D seed point (64); and adapt the shape model (66) to represent the structure of interest (60), thereby yielding an adapted shape model.

Abstract translation: 一种用于生成或重建对应于感兴趣结构（60）的三维（3D）图像的方法，包括：获取与感兴趣结构相对应的多个图像投影（60）; 在选定的3D种子点（64）处应用形状模型（66）; 以及使形状模型（66）适应于表示感兴趣的结构（60），产生适应的形状模型。 一种用于三维（3D）图像的生成和重建的系统。 系统（10）包括：成像系统（12），被配置为提供对应于感兴趣结构（60）的投影数据; 以及与成像系统（50）可操作地通信的控制器（50）。 控制器（50）被配置为：接收投影数据（64）; 在选定的3D种子点（64）上应用形状模型（66）; 并适应形状模型（66）来表示感兴趣的结构（60），从而产生适应的形状模型。

公开(公告)号：US09280837B2

公开(公告)日：2016-03-08

申请号：US13121800

申请日：2009-10-07

Applicant: Michael Grass ,  Dirk Schaefer ,  Gert Antonius Franciscus Schoonenberg

Inventor： Michael Grass ,  Dirk Schaefer ,  Gert Antonius Franciscus Schoonenberg

IPC: G06F19/00 ,  G06T11/00 ,  G06T15/08 ,  A61B6/00 ,  A61B6/06

CPC classification number: G06T11/008 ,  A61B6/06 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/504 ,  A61B6/5247 ,  A61B6/542 ,  G06F19/00 ,  G06F19/321 ,  G06T15/08 ,  G06T2211/404 ,  G16H40/63

Abstract: The present invention refers to an angiographic image acquisition system and method which can beneficially be used in the scope of minimally invasive image-guided interventions. In particular, the present invention relates to a system and method for graphically visualizing a pre-interventionally virtual 3D representation of a patient's coronary artery tree's vessel segments in a region of interest of a patient's cardiovascular system to be three-dimensionally reconstructed. Optionally, this 3D representation can then be fused with an intraoperatively acquired fluoroscopic 2D live image of an interventional tool. According to the present invention, said method comprises the steps of subjecting the image data set of the 3D representation associated with the precalculated optimal viewing angle to a 3D segmentation algorithm (S4) in order to find the contours of a target structure or lesion to be examined and interventionally treated within a region of interest and automatically adjusting (S5) a collimator wedge position and/or aperture of a shutter mechanism used for collimating an X-ray beam emitted by an X-ray source of a C-arm-based 3D rotational angiography device or rotational gantry-based CT imaging system to which the patient is exposed during an image-guided radiographic examination procedure based on data obtained as a result of said segmentation which indicate the contour and size of said target structure or lesion. The aim is to reduce the region of interest to a field of view that covers said target structure or lesion together with a user-definable portion of the surrounding vasculature.

Abstract translation: 本发明涉及一种血管造影图像采集系统和方法，可有利地用于微创图像引导干预的范围。 特别地，本发明涉及一种用于以图形方式可视化患者心血管系统感兴趣区域中的患者冠状动脉树血管段的预先介入虚拟3D表示以进行三维重构的系统和方法。 可选地，该3D表示随后可以与介入工具的术中获取的荧光透视2D实况图像融合。 根据本发明，所述方法包括以下步骤：将与预先计算的最佳视角相关联的3D表示的图像数据集进行3D分割算法（S4），以便将目标结构或病变的轮廓找到为 在感兴趣区域内进行检查和介入处理，并自动调整（S5）用于准直由基于C臂的3D的X射线源发射的X射线束的快门机构的准直器楔位置和/或孔径 旋转血管造影装置或基于旋转台架的CT成像系统，其中基于由所述分割结果获得的指示所述目标结构或病变的轮廓和大小的图像引导放射线检查程序期间所述患者暴露于所述CT成像系统。 目的是将感兴趣的区域减少到覆盖所述目标结构或病变的视野以及周围脉管系统的用户可定义的部分。

公开(公告)号：US20130322724A1

公开(公告)日：2013-12-05

申请号：US13810680

申请日：2011-07-15

Applicant: Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

Inventor： Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  A61B6/12 ,  A61B6/463 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5235 ,  A61B90/37 ,  A61B2090/364 ,  A61B2090/365 ,  A61B2090/3764 ,  G06T7/32 ,  G06T19/00 ,  G06T2207/10121 ,  G06T2207/30101

Abstract: The invention relates to adaptive roadmapping providing improved information to the user, comprising the following steps: providing pre-navigation image data representing at least a part of a vascular structure comprising a tree-like structure with a plurality of sub-trees; generating a vessel representation on the basis of pre-navigation image data; acquiring live image data of the object, which object comprises the vascular structure; wherein the vascular structure contains an element of interest; determining spatial relation of the pre-navigation image data and the live image data; analysing the live image data by identifying and localizing the element in the live image data; determining a sub-tree in which the element is positioned, wherein the determining is based on the localization of the element and on the spatial relation; and selecting a portion of the vascular structure based on the determined sub-tree; generating a combination of the live image data and an image of the selected portion of the vascular structure; and displaying the combination as a tailored roadmap. The element may be physical object, for example an interventional tool or device.

Abstract translation: 本发明涉及向用户提供改进信息的自适应路线图，包括以下步骤：提供表示包括具有多个子树的树状结构的血管结构的至少一部分的导航前图像数据; 基于导航前图像数据生成船舶表示; 获取对象的实时图像数据，该对象包括血管结构; 其中所述血管结构含有感兴趣的元件; 确定所述导航前图像数据和实况图像数据的空间关系; 通过识别和定位实时图像数据中的元素来分析实况图像数据; 确定所述元素所在的子树，其中所述确定基于所述元素的定位和所述空间关系; 以及基于所确定的子树选择所述血管结构的一部分; 生成活体图像数据和血管结构的所选部分的图像的组合; 并将该组合显示为定制的路线图。 该元件可以是物理对象，例如介入工具或设备。

公开(公告)号：US08184883B2

公开(公告)日：2012-05-22

申请号：US12093458

申请日：2006-11-14

Applicant: Michael Grass ,  Dirk Schaefer ,  Udo Van Stevendaal

Inventor： Michael Grass ,  Dirk Schaefer ,  Udo Van Stevendaal

IPC: G06K9/00 ,  A61B6/03

CPC classification number: A61B6/032 ,  A61B6/027 ,  A61B6/12 ,  A61B6/541 ,  G06T7/20 ,  G06T11/006 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2211/412

Abstract: Cardiac CT imaging using gated reconstruction is currently limited in its temporal and spatial resolution. According to an exemplary embodiment of the present invention, an examination apparatus is provided in which an identification of a high contrast object is performed. This high contrast object is then followed through the phases, resulting in a motion vector field of the high contrast object, on the basis of which a motion compensated reconstruction is then performed.

Abstract translation: 使用门控重建的心脏CT成像目前在其时间和空间分辨率方面受到限制。 根据本发明的示例性实施例，提供一种检查装置，其中执行高对比度对象的识别。 然后，该对比度较高的对象随后进入相位，导致高对比度对象的运动矢量场，然后基于此进行运动补偿重建。

公开(公告)号：US08175356B2

公开(公告)日：2012-05-08

申请号：US12513370

申请日：2007-10-24

Applicant: Babak Movassaghi ,  Michael Grass ,  Dirk Schaefer

Inventor： Babak Movassaghi ,  Michael Grass ,  Dirk Schaefer

IPC: G06K9/00

CPC classification number: A61B6/5217 ,  A61B6/027 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  G06T7/254 ,  G06T2207/30048

Abstract: For the reconstruction of the coronary arteries from rotational coronary angiography data, a crucial point is the selection of the optimal cardiac phase for data reconstruction. According to an exemplary embodiment of the present invention, an automatic approach for deriving optimal reconstruction windows is provided by fully automatically selecting the optimal cardiac phase on the basis of a delayed acquisition protocol where at least one heart phase needs to be acquired in a static projection geometry.

Abstract translation: 对于从旋转冠状动脉造影数据重建冠状动脉，关键点是数据重建的最佳心脏相位的选择。 根据本发明的示例性实施例，通过基于延迟获取协议完全自动选择最佳心脏相位来提供用于导出最佳重建窗口的自动方法，其中需要在静态投影中获取至少一个心脏相位 几何。

公开(公告)号：US20120014582A1

公开(公告)日：2012-01-19

申请号：US13254001

申请日：2010-02-18

Applicant: Dirk Schaefer ,  Michael Grass

Inventor： Dirk Schaefer ,  Michael Grass

IPC: G06K9/00

CPC classification number: G06T11/005 ,  A61B6/027 ,  A61B6/032

Abstract: A method and apparatus are provided to reconstruct projection data obtained from CT imaging devices with offset detector geometries. According to one aspect of the present invention, a method is provided to reconstruct projection data obtained from CT imaging devices with offset detector geometries that includes the following steps: (i) matching projection data measured at opposing sides of the acquisition trajectory and splicing them together to generate a full, non-truncated projection data set; (ii) differentiation of the projection data; (iii) filtering the differentiated projection data with a filter, such as for example a Hilbert filter; (iv) applying redundancy weighting to the filtered projection data; and (v) back-projecting the redundancy weighted projection data to generate image data.

Abstract translation: 提供了一种方法和装置来重构从具有偏移检测器几何形状的CT成像装置获得的投影数据。 根据本发明的一个方面，提供了一种用于重建从具有偏移检测器几何的CT成像装置获得的投影数据的方法，其包括以下步骤：（i）匹配在获取轨迹的相对侧测量的投影数据并将它们拼接在一起 生成一个完整的，非截断的投影数据集; （ii）投影数据的区分; （iii）用滤波器（例如希尔伯特滤波器）过滤差分投影数据; （iv）对过滤的投影数据应用冗余权重; 和（v）反向投影冗余加权投影数据以产生图像数据。

公开(公告)号：US20100232672A1

公开(公告)日：2010-09-16

申请号：US12673508

申请日：2008-08-12

Applicant: Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

Inventor： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

IPC: G06K9/00 ,  G06K9/40

CPC classification number: G06T5/50 ,  G06T7/12 ,  G06T7/155 ,  G06T2207/10081 ,  G06T2207/10121 ,  G06T2207/30021

Abstract: A system (900) and method for automatic projection-based removing of high-contrast artificial objects from a medical image is provided. The method comprises performing a low-pass filtering (1100) to the two-dimensional image (100, 500, 1000) using a filter width range (1110) corresponding to structures of a line-shaped artificial object to generate a low-pass filtered intensity image and performing an evaluation of the Hessian matrix of each pixels of the low-pass filtered intensity image for locating and enhancing the structure of the line-shaped artificial object to generate a multi-scale filtered intensity image, wherein predefined scaling widths are used in order to avoid the locating and enhancing of larger structures.

Abstract translation: 提供了一种用于从医学图像自动投影去除高对比度人造物体的系统（900）和方法。 该方法包括使用对应于线状人造物体的结构的滤波器宽度范围（1110）对二维图像（100,500,1000）进行低通滤波（1100），以生成低通滤波 强度图像，并对低通滤波强度图像的每个像素的Hessian矩阵进行评估，以定位和增强线状人造物体的结构，以生成多尺度滤波强度图像，其中使用预定义的缩放宽度 以避免更大的结构的定位和增强。

公开(公告)号：US20100074485A1

公开(公告)日：2010-03-25

申请号：US12513370

申请日：2007-10-24

Applicant: Babak Movassaghi ,  Michael Grass ,  Dirk Schaefer

Inventor： Babak Movassaghi ,  Michael Grass ,  Dirk Schaefer

IPC: G06K9/00

CPC classification number: A61B6/5217 ,  A61B6/027 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  G06T7/254 ,  G06T2207/30048

Abstract: For the reconstruction of the coronary arteries from rotational coronary angiography data, a crucial point is the selection of the optimal cardiac phase for data reconstruction. According to an exemplary embodiment of the present invention, an automatic approach for deriving optimal reconstruction windows is provided by fully automatically selecting the optimal cardiac phase on the basis of a delayed acquisition protocol where at least one heart phase needs to be acquired in a static projection geometry.

Abstract translation: 对于从旋转冠状动脉造影数据重建冠状动脉，关键点是数据重建的最佳心脏相位的选择。 根据本发明的示例性实施例，通过基于延迟获取协议完全自动选择最佳心脏相位来提供用于导出最佳重建窗口的自动方法，其中需要在静态投影中获取至少一个心脏相位 几何。

公开(公告)号：US20090141935A1

公开(公告)日：2009-06-04

申请号：US12093458

申请日：2006-11-14

Applicant: Michael Grass ,  Dirk Schaefer ,  Udo Van Stevendaal

Inventor： Michael Grass ,  Dirk Schaefer ,  Udo Van Stevendaal

IPC: G06K9/00

CPC classification number: A61B6/032 ,  A61B6/027 ,  A61B6/12 ,  A61B6/541 ,  G06T7/20 ,  G06T11/006 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2211/412

Abstract: Cardiac CT imaging using gated reconstruction is currently limited in its temporal and spatial resolution. According to an exemplary embodiment of the present invention, an examination apparatus is provided in which an identification of a high contrast object is performed. This high contrast object is then followed through the phases, resulting in a motion vector field of the high contrast object, on the basis of which a motion compensated reconstruction is then performed.

Abstract translation: 使用门控重建的心脏CT成像目前在其时间和空间分辨率方面受到限制。 根据本发明的示例性实施例，提供一种检查装置，其中执行高对比度对象的识别。 然后，该对比度较高的对象随后进入相位，导致高对比度对象的运动矢量场，然后基于此进行运动补偿重建。

公开(公告)号：US07659339B2

公开(公告)日：2010-02-09

申请号：US11484493

申请日：2006-07-11

Applicant: Victor Nasreddine ,  Sharon X. Guo ,  Dirk Schaefer ,  Christopher M. Ong

Inventor： Victor Nasreddine ,  Sharon X. Guo ,  Dirk Schaefer ,  Christopher M. Ong

IPC: C08L77/00 ,  C08L9/00

CPC classification number: C08L77/00 ,  C08L9/02 ,  C08L13/00 ,  C08L15/005 ,  C08L33/18 ,  C08L33/22 ,  C08L77/02 ,  C08L77/06 ,  C08L2666/14 ,  C08L2666/08 ,  C08L2666/26 ,  C08L2666/04

Abstract: The present invention relates to thermoplastic vulcanizates (TPVs) based on low Mooney, optionally hydrogenated nitrile butadiene rubber and polyamides. The present invention also relates to TPVs based on low Mooney, optionally, hydrogenated nitrile terpolymers and polyamides. TPVs prepared according to the present invention have improved morphology, smaller rubber particle size, and improved processability compared to TPVs containing non-low Mooney, optionally hydrogenated nitrile butadiene rubber.

Abstract translation: 本发明涉及基于低门尼，任选氢化丁腈橡胶和聚酰胺的热塑性硫化橡胶（TPV）。 本发明还涉及基于低门尼，任选的氢化腈三元共聚物和聚酰胺的TPV。 根据本发明制备的TPV与含有非低门尼，任选氢化的丁腈橡胶的TPV相比具有改进的形态，较小的橡胶粒度和改进的加工性能。