公开(公告)号：US09165385B2

公开(公告)日：2015-10-20

申请号：US13321214

申请日：2010-05-12

Applicant: Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

Inventor： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

IPC: G06F17/50 ,  G06T11/00 ,  A61B6/03 ,  A61B6/00

CPC classification number: G06T11/005 ,  A61B6/032 ,  A61B6/488

Abstract: A method includes generating with a processor (122) a three-dimensional subject specific model of structure of interest of a subject to be scanned based on a general three-dimensional model and pre-scan image data acquired by an imaging system (100) generating with the processor (122) an imaging plan for the subject based on the three-dimensional subject specific model.

Abstract translation: 一种方法包括基于通常的三维模型和由成像系统（100）获取的预扫描图像数据，利用处理器（122）生成待扫描的对象的感兴趣结构的三维对象特定的模型， 与处理器（122）基于三维主题特定模型的对象的成像计划。

公开(公告)号：US08446408B2

公开(公告)日：2013-05-21

申请号：US11997340

申请日：2006-07-12

Applicant: Michael Grass ,  Volker Rasche ,  Dirk Schaefer

Inventor： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

IPC: G06T15/00

CPC classification number: G06T11/005 ,  G06T2211/412

Abstract: A method for generating or reconstruction of three-dimensional (3D) images corresponding to a structure of interest (60) including: acquiring a plurality of image projections corresponding to a structure of interest (60); applying a shape model (66) at a selected 3D seed point (64); and adapting the shape model (66) to represent the structure of interest (60), yielding an adapted shape model. A system for generation and reconstruction of three-dimensional (3D) images. The system (10) includes: an imaging system (12) configured to provide projection data corresponding to a structure of interest (60); and a controller (50) in operable communication with the imaging system (50). The controller (50) is configured to: receive the projection data, (64); apply a shape model (66) at a selected 3D seed point (64); and adapt the shape model (66) to represent the structure of interest (60), thereby yielding an adapted shape model.

Abstract translation: 一种用于生成或重建对应于感兴趣结构（60）的三维（3D）图像的方法，包括：获取与感兴趣结构相对应的多个图像投影（60）; 在选定的3D种子点（64）处应用形状模型（66）; 以及使形状模型（66）适应于表示感兴趣的结构（60），产生适应的形状模型。 一种用于三维（3D）图像的生成和重建的系统。 系统（10）包括：成像系统（12），被配置为提供对应于感兴趣结构（60）的投影数据; 以及与成像系统（50）可操作地通信的控制器（50）。 控制器（50）被配置为：接收投影数据（64）; 在选定的3D种子点（64）上应用形状模型（66）; 并适应形状模型（66）来表示感兴趣的结构（60），从而产生适应的形状模型。

公开(公告)号：US20110182492A1

公开(公告)日：2011-07-28

申请号：US13121800

申请日：2009-10-07

Applicant: Michael Grass ,  Dirk Schaefer ,  Gert Antonius Franciscus Schoonenberg

Inventor： Michael Grass ,  Dirk Schaefer ,  Gert Antonius Franciscus Schoonenberg

IPC: G06K9/00 ,  G21K1/04

CPC classification number: G06T11/008 ,  A61B6/06 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/504 ,  A61B6/5247 ,  A61B6/542 ,  G06F19/00 ,  G06F19/321 ,  G06T15/08 ,  G06T2211/404 ,  G16H40/63

Abstract: The present invention refers to an angiographic image acquisition system and method which can beneficially be used in the scope of minimally invasive image-guided interventions. In particular, the present invention relates to a system and method for graphically visualizing a pre-interventionally virtual 3D representation of a patient's coronary artery tree's vessel segments in a region of interest of a patient's cardiovascular system to be three-dimensionally reconstructed. Optionally, this 3D representation can then be fused with an intraoperatively acquired fluoroscopic 2D live image of an interventional tool. According to the present invention, said method comprises the steps of subjecting the image data set of the 3D representation associated with the precalculated optimal viewing angle to a 3D segmentation algorithm (S4) in order to find the contours of a target structure or lesion to be examined and interventionally treated within a region of interest and automatically adjusting (S5) a collimator wedge position and/or aperture of a shutter mechanism used for collimating an X-ray beam emitted by an X-ray source of a C-arm-based 3D rotational angiography device or rotational gantry-based CT imaging system to which the patient is exposed during an image-guided radiographic examination procedure based on data obtained as a result of said segmentation which indicate the contour and size of said target structure or lesion. The aim is to reduce the region of interest to a field of view that covers said target structure or lesion together with a user-definable portion of the surrounding vasculature.

Abstract translation: 本发明涉及一种血管造影图像采集系统和方法，可有利地用于微创图像引导干预的范围。 特别地，本发明涉及一种用于以图形方式可视化患者心血管系统感兴趣区域中的患者冠状动脉树血管段的预先介入虚拟3D表示以进行三维重构的系统和方法。 可选地，该3D表示随后可以与介入工具的术中获取的荧光透视2D实况图像融合。 根据本发明，所述方法包括以下步骤：将与预先计算的最佳视角相关联的3D表示的图像数据集进行3D分割算法（S4），以便将目标结构或病变的轮廓找到为 在感兴趣区域内进行检查和介入处理，并自动调整（S5）用于准直由基于C臂的3D的X射线源发射的X射线束的快门机构的准直器楔位置和/或孔径 旋转血管造影装置或基于旋转台架的CT成像系统，其中基于由所述分割结果获得的指示所述目标结构或病变的轮廓和大小的图像引导放射线检查程序期间所述患者暴露于所述CT成像系统。 目的是将感兴趣的区域减少到覆盖所述目标结构或病变的视野以及周围脉管系统的用户可定义的部分。

公开(公告)号：US20100316270A1

公开(公告)日：2010-12-16

申请号：US12808682

申请日：2008-12-16

Applicant: Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

Inventor： Klaus Erhard ,  Michael Grass ,  Dirk Schaefer

IPC: G06K9/00

CPC classification number: G06T11/006 ,  G06T2211/432

Abstract: The invention proposes a 3D reconstruction of a body and a body contour from transversally truncated projections using a polyhedral object model. Possible clinical applications arise in the field of guided biopsies on acquisition systems equipped with a flat panel detector, where truncated projections cannot be avoided in thorax and abdominal scan protocols. From, for example, a rotational run both a 3D volume reconstruction and a surface mesh reconstruction of a patient's shape is generated and then visualized simultaneously in order to help the physician guide the biopsy device and judge the distance from the patient's skin to the tissue of interest inside the reconstructed volume.

Abstract translation: 本发明提出了使用多面体对象模型从横截面的突起中进行身体和身体轮廓的3D重建。 可能的临床应用出现在配备有平板检测器的采集系统上的引导活检领域，其中在胸部和腹部扫描方案中不能避免截断的突起。 例如，通过旋转运行，生成3D体积重建和患者形状的表面网格重建，然后同时可视化，以帮助医生引导活检装置并判断从患者皮肤到组织的距离 重建体积内的兴趣。

公开(公告)号：US20100189337A1

公开(公告)日：2010-07-29

申请号：US12668043

申请日：2008-07-08

Applicant: Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

Inventor： Uwe Jandt ,  Dirk Schaefer ,  Michael Grass

IPC: G06K9/00

CPC classification number: A61B6/504 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/481 ,  A61B6/541 ,  G06T7/0012 ,  G06T7/564 ,  G06T7/596 ,  G06T7/60 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/08 ,  G06T2207/10112 ,  G06T2207/10116 ,  G06T2207/20044 ,  G06T2207/30101 ,  G06T2211/404 ,  G06T2211/412

Abstract: A method and an apparatus for acquiring 3-dimensional images of coronary vessels (11), particularly of coronary veins, is proposed. 2-dimensional X-ray images (13) are acquired within a same phase of a cardiac motion. Then, a 3-dimensional centerline model (15) is generated based on these 2-dimensional images. From 2-dimensional projections of the centerline model into respective projection planes, the local diameters (w) of the vessels in the projection plane can be derived. Having the diameters, a 3-dimensional hull model of the vessel system can be generated and, optionally, 4-dimensional information about the vessel movement can be derived.

Abstract translation: 提出了一种用于获取冠状血管（11），特别是冠状静脉的三维图像的方法和装置。 在心脏运动的相同相位中获取2维X射线图像（13）。 然后，基于这些二维图像生成3维中心线模型（15）。 从中心线模型的二维投影到相应的投影平面，可以推导投影平面中容器的局部直径（w）。 具有直径，可以产生容器系统的3维船体模型，并且可以导出关于船只运动的4维信息。

公开(公告)号：US20090238412A1

公开(公告)日：2009-09-24

申请号：US12305996

申请日：2007-06-18

Applicant: Michael Grass ,  Dirk Schaefer ,  Babak Movassaghi

Inventor： Michael Grass ,  Dirk Schaefer ,  Babak Movassaghi

IPC: G06T7/20 ,  G06T7/00

CPC classification number: A61B6/504 ,  A61B6/032 ,  A61B6/469 ,  A61B6/5264 ,  A61B6/527 ,  A61B6/541

Abstract: The analysis of a stenosis of a coronary vessel in three dimensions requires a motion compensated reconstruction. According to an exemplary embodiment of the present invention, an examination apparatus for local motion compensated reconstruction data set is provided, wherein the local motion compensated reconstruction vectors relating to a start point and an end point of the stenosis.

Abstract translation: 三维冠状动脉血管狭窄的分析需要运动补偿重建。 根据本发明的示例性实施例，提供了一种用于局部运动补偿重建数据集的检查装置，其中与狭窄的起始点和终点有关的局部运动补偿重建向量。

公开(公告)号：US09672651B2

公开(公告)日：2017-06-06

申请号：US12445752

申请日：2007-10-10

Applicant: Dirk Schaefer ,  Michael Grass

Inventor： Dirk Schaefer ,  Michael Grass

IPC: G06T13/20 ,  G06T11/00 ,  A61B6/02 ,  A61B6/00 ,  A61B8/13

CPC classification number: G06T13/20 ,  A61B6/02 ,  A61B6/4441 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  A61B8/13 ,  G06T11/006 ,  G06T2211/404 ,  G06T2211/412

Abstract: A method for four dimensional reconstruction of regions exhibiting multiple phases of periodic motion includes the operation of building one or more 3-D reconstructions using a set of 2-D projections. The method further includes the operation of deriving one or more 3-D model segments from each of the one or more 3-D reconstructions, wherein a plurality of 3-D model segments are formed thereby, and wherein each of the one or more 3-D model segments is derived from a single one of the one or more 3-D model segments. The plurality of derived 3-D model segments forms a 4-D reconstruction of the region of interest.

公开(公告)号：US09053535B2

公开(公告)日：2015-06-09

申请号：US13810680

申请日：2011-07-15

Applicant: Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

Inventor： Raoul Florent ,  Vincent Auvray ,  Michael Grass ,  Dirk Schaefer ,  Gert Schoonenberg

IPC: G06K9/00 ,  G06T7/00 ,  A61B6/12 ,  A61B6/00 ,  A61B19/00 ,  G06T19/00

CPC classification number: G06T7/0012 ,  A61B6/12 ,  A61B6/463 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5235 ,  A61B90/37 ,  A61B2090/364 ,  A61B2090/365 ,  A61B2090/3764 ,  G06T7/32 ,  G06T19/00 ,  G06T2207/10121 ,  G06T2207/30101

Abstract: An adaptive roadmapping device and method for examination of an object include providing pre-navigation image data representing part of the object being a vascular structure including an element of interest and having a tree-like structure with a plurality of sub-trees; generating a vessel representation based on the pre-navigation image data; acquiring live image data of the object; determining spatial relation of the pre-navigation image data and the live image data; analyzing the live image data by identifying and localizing the element in the live image data; determining a sub-tree in which the element is positioned, where the determining is based on the localization of the element and on the spatial relation; selecting a portion of the vascular structure based on the determined sub-tree; generating a combination of the live image data and an image of the selected portion of the vascular structure; and displaying the combination as a tailored roadmap.

Abstract translation: 用于检查对象的自适应路线图设备和方法包括提供表示作为包括感兴趣元素并且具有多个子树的树状结构的血管结构的对象的一部分的导航前图像数据; 基于导航前图像数据生成船舶表示; 获取对象的实时图像数据; 确定所述导航前图像数据和实况图像数据的空间关系; 通过识别和定位实时图像数据中的元素来分析实况图像数据; 确定元素位于其中的子树，其中确定基于元素的定位和空间关系; 基于确定的子树选择血管结构的一部分; 生成活体图像数据和血管结构的所选部分的图像的组合; 并将该组合显示为定制的路线图。

公开(公告)号：US20100014726A1

公开(公告)日：2010-01-21

申请号：US12302897

申请日：2007-05-21

Applicant: Dirk Schaefer ,  Andreas Engler ,  Babak Movassaghi ,  Volker Rasche ,  Michael Grass

Inventor： Dirk Schaefer ,  Andreas Engler ,  Babak Movassaghi ,  Volker Rasche ,  Michael Grass

IPC: G06K9/00 ,  G06K9/36

CPC classification number: A61B6/504 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/481 ,  A61B6/5288 ,  A61B6/541 ,  G06T3/0037 ,  G06T7/20 ,  G06T2207/10081 ,  G06T2207/20016 ,  G06T2207/30101

Abstract: In three-dimensional rotational x-ray coronary imaging problems may arise when estimating the motion of small vessels. According to an exemplary embodiment of the present invention, an examination apparatus is provided which is adapted for performing a hierarchical motion estimation by global affine transformation for every heart phase, followed by vessel branch selective affine and non-affine transformations. This may provide for an improved image quality.

Abstract translation: 在估计小血管运动时可能出现三维旋转X射线冠状动脉成像问题。 根据本发明的示例性实施例，提供了一种检查装置，其适用于通过用于每个心脏相的全局仿射变换执行分层运动估计，随后是血管分支选择仿射和非仿射变换。 这可以提供改进的图像质量。

公开(公告)号：US20080205722A1

公开(公告)日：2008-08-28

申请号：US12063682

申请日：2006-08-04

Applicant: Dirk Schaefer ,  Michael Grass ,  Uwe Jandt

Inventor： Dirk Schaefer ,  Michael Grass ,  Uwe Jandt

IPC: G06K9/00

CPC classification number: G06T7/11 ,  G06T2207/10121 ,  G06T2207/20132 ,  G06T2207/20156 ,  G06T2207/30101

Abstract: A method for computer-aided four-dimensional (4D) modeling of an anatomical object comprises acquiring a set of three-dimensional (3D) models representing a plurality of static states of the object throughout a cycle. A 4D correspondency estimation is performed on the set of 3D models to determine which points of the 3D models most likely correspond to each other, wherein the 4D correspondency estimation includes one or more of (i) defining a reference phase, (ii) performing vessel-oriented correspondency estimation, and (iii) post-processing of 4D motion data. The method further comprises automatic 3D modeling with a front propagation algorithm.

Abstract translation: 用于解剖对象的计算机辅助四维（4D）建模的方法包括在整个循环中获取表示对象的多个静态的一组三维（3D）模型。 对所述3D模型集进行4D对应度估计，以确定所述3D模型中哪些点最可能彼此对应，其中所述4D对应度估计包括以下中的一个或多个（i）定义参考相位，（ii）执行血管 （iii）4D运动数据的后处理。 该方法还包括利用前向传播算法的自动3D建模。