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公开(公告)号:US10758342B2
公开(公告)日:2020-09-01
申请号:US16171263
申请日:2018-10-25
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic mitral valve can include an outer frame, an inner frame, a valve structure, and a sealing member. The outer frame comprises a plurality of first struts arranged in a lattice pattern and defining a first lumen. The outer frame is self-expandable from a compressed state to an expanded state. The inner frame comprises a plurality of second struts arranged in a lattice pattern and defining a second lumen. The inner frame is disposed within the first lumen of the outer frame, is self-expandable from a compressed state to an expanded state. The valve structure comprises three leaflets made from pericardium and is mounted within the second lumen of the inner frame. The sealing member is coupled to and extends radially outwardly from an atrial end of the outer frame and is configured to engage native tissue of the heart on an atrial side of the native mitral valve.
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公开(公告)号:US10111748B2
公开(公告)日:2018-10-30
申请号:US15455713
申请日:2017-03-10
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
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公开(公告)号:US20160338826A1
公开(公告)日:2016-11-24
申请号:US15227238
申请日:2016-08-03
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
Abstract translation: 用于植入天然二尖瓣的假体装置包括用于放置在天然二尖瓣环内的主体。 主体可压缩到径向压缩状态,用于输送到心脏中,并且可以从压缩状态自扩张到用于植入的径向扩张状态。 阀结构安装在主体的内腔中,优选形成由心包制成的三个传单。 心房密封构件沿着主体的心房部分设置,并且心室锚固件联接到主体的心室部分。 心房密封件妨碍主体和天然环之间的血液流动。 心室锚定位于主体外部,用于捕获主体和心室锚之间的原生二尖瓣小叶。
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公开(公告)号:US20150320553A1
公开(公告)日:2015-11-12
申请号:US14801713
申请日:2015-07-16
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic apparatus configured for implantation in the native mitral valve region of the heart includes a main body that is self-expandable from a compressed state to a radially expanded state. The prosthetic apparatus comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body for capturing a native valve leaflet between the anchor and an outer surface of the main body. In one preferred method of implantation, the prosthetic apparatus is rotated within the native mitral valve region such that a portion of the anchor moves horizontally behind adjacent chordae for anchoring the prosthetic apparatus in the native mitral valve.
Abstract translation: 构造成用于植入心脏的天然二尖瓣区域的假体装置包括从压缩状态向径向展开状态自扩张的主体。 假体装置包括耦合到主体并且设置在主体外部的至少一个心室锚,用于捕获锚固体和主体的外表面之间的天然瓣膜。 在一种优选的植入方法中,假体装置在天然二尖瓣区域内旋转,使得锚的一部分水平地移动到相邻的腱索之后,以将假体装置锚定在天然二尖瓣中。
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公开(公告)号:US08926691B2
公开(公告)日:2015-01-06
申请号:US14025594
申请日:2013-09-12
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Oba
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: Embodiments of an apparatus for treating a deficient mitral valve include an expandable spacer configured for placement between the native leaflets of the mitral valve, the spacer anchorable to a wall of the ventricle. Methods and apparatus for delivering and implanting the prosthetic are also described.
Abstract translation: 用于治疗缺陷型二尖瓣的装置的实施例包括可扩张间隔物,其被配置用于放置在二尖瓣的天然传播片之间,该间隔物可锚定到心室的壁。 还描述了用于递送和植入假体的方法和装置。
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公开(公告)号:US20140222136A1
公开(公告)日:2014-08-07
申请号:US14171603
申请日:2014-02-03
Applicant: Edwards Lifesciences Corporation
Inventor: Stephen C. Geist , Robert C. Taft , Travis Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61B6/4441 , A61B8/12 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. One embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve member. In some cases, the prosthetic valves also include ventricular anchors and/or an atrial portion coupled to and disposed outside of the main body. Methods, devices, and systems for delivering such prosthetic valves to the native mitral valve and implanting them therein are also provided.
Abstract translation: 提供了用于植入在天然二尖瓣内的人工瓣膜的实施例。 假体瓣膜的一个实施例包括可径向压缩的主体和单向阀构件。 在一些情况下,假体瓣膜还包括联接到并设置在主体外侧的心室锚和/或心房部分。 还提供了用于将这种假性瓣膜递送到天然二尖瓣并将其植入其中的方法,装置和系统。
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公开(公告)号:US20250152339A1
公开(公告)日:2025-05-15
申请号:US19024895
申请日:2025-01-16
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic heart valve including a multi-part frame having an annular main body formed from a plurality of struts, an atrial anchor that extends radially outward from an inflow end portion of the main body, one or more ventricular anchors that are configured to be positioned behind a native valve leaflet, and a valve structure disposed in a lumen of the main body. Each of the ventricular anchors includes first and second end portions coupled to the outflow end portion of the main body and an intermediate portion forming a bend that forms a free end portion of the ventricular anchor that extends toward an inflow end portion of the main body. The multi-part frame is radially compressible for delivery within a sheath of a delivery catheter and is self-expandable for deployment within an annulus of a native valve.
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公开(公告)号:US20250143877A1
公开(公告)日:2025-05-08
申请号:US19017165
申请日:2025-01-10
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
Abstract: A prosthetic device includes a main body, a first anchor, and a second anchor. The main body has an atrial end and a ventricular end. The main body tapers from the atrial end to the ventricular end. The first and second anchors are coupled to the main body and are movable toward and away from the main body.
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公开(公告)号:US20240407914A1
公开(公告)日:2024-12-12
申请号:US18811644
申请日:2024-08-21
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic heart valve includes a multi-part frame having a first annular body and an anchor component that includes a second annular body circumscribing the first annular body. The first annular body includes a plurality of struts arranged in a lattice pattern and defining a lumen. The anchor component further includes one or more ventricular anchors extending from the second annular body toward an inflow end portion of the first annular body. A fabric layer is disposed on an inner surface of the first annular body and sutured to the struts. A valve structure including three leaflets is disposed within the lumen and inlet ends of the leaflets are sutured to the fabric layer. The multi-part frame is radially compressible for delivery within a sheath of a delivery catheter and is self-expandable for deployment within an annulus of a native valve.
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公开(公告)号:US12083010B2
公开(公告)日:2024-09-10
申请号:US16670449
申请日:2019-10-31
Applicant: Edwards Lifesciences Corporation
Inventor: Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61B6/4441 , A61B8/12 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: A method of implanting a prosthetic apparatus preferably includes delivering the prosthetic apparatus to a native mitral valve and exposing ventricular anchors and a spacer body of the prosthetic apparatus from a distal end portion of a delivery apparatus. The ventricular anchors are controllably and forcibly expanded outwardly from the spacer body to an expanded configuration. The prosthetic apparatus is positioned relative to the native mitral valve such that native mitral valve leaflets are located between the ventricular anchors and the spacer body. The ventricular anchors are then contracted radially inwardly toward the spacer body to a compressed configuration. In the compressed configuration, the native mitral valve leaflets are secured between the ventricular anchors and the spacer body. After implantation, the spacer body is held between the native mitral valve leaflets, thereby blocking regurgitation and improving the function of the native mitral valve.
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