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公开(公告)号:US09717591B2
公开(公告)日:2017-08-01
申请号:US15227238
申请日:2016-08-03
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
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公开(公告)号:US20140213970A1
公开(公告)日:2014-07-31
申请号:US14098078
申请日:2013-12-05
Applicant: Edwards Lifesciences Corporation
Inventor: Yidong M. Zhu , Marlowe E. Patterson
CPC classification number: A61M25/1002 , A61M25/1029 , A61M2025/1084 , A61M2025/1086 , B29C48/0017 , B29C48/09 , B29C48/19 , B29C48/20 , B29C49/04 , B29C49/20 , B29C49/22 , B29L2031/7543
Abstract: A process for forming a catheter balloon includes subjecting a tubular parison in a mold to molding fluid pressure. The resulting catheter balloon includes a balloon portion having two ends and tubular leg portions extending from either end. The ends of the balloon portion are tapered to the tubular leg portions. The tapered ends have alternating elongate areas of greater and lesser resistance to deformation displaced circumferentially about the tapered ends. The elongate areas of greater and lesser resistance to deformation can include ridges which are either longitudinal or spiraled or rods imbedded in the body of the balloon. While in the mold, the tubular legs are drawn axially sufficiently to form permanent creases in the tapered ends. This drawing may be sufficient to cause the material of the tapered ends to exceed the yield strength, particularly with the balloon material in a malleable state.
Abstract translation: 用于形成导管球囊的方法包括使管型坯在模具中成型流体压力。 所得到的导管球囊包括具有两端的球囊部分和从任一端延伸的管状腿部分。 球囊部分的端部与管状腿部成锥形。 锥形端部具有交替的细长区域,其具有更大和更小的抵抗围绕锥形端部周向移位的变形。 具有更大和更小抗变形能力的细长区域可以包括纵向或螺旋形的脊或嵌入气球体内的杆。 在模具中,管状支柱被轴向拉伸以在锥形端部形成永久的折痕。 该图可能足以导致锥形端部的材料超过屈服强度,特别是气球材料在可延展状态下。
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公开(公告)号:US20240173122A1
公开(公告)日:2024-05-30
申请号:US18427999
申请日:2024-01-31
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic spacer assembly includes a spacer body, a first anchor, and a second anchor. The first anchor and the second anchor each extend from the spacer body. The spacer body is radially compressible and self-expandable. The spacer body is configured for placement between the anterior and posterior native valve leaflets.
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公开(公告)号:US10507102B2
公开(公告)日:2019-12-17
申请号:US15945878
申请日:2018-04-05
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
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公开(公告)号:US20170209264A1
公开(公告)日:2017-07-27
申请号:US15455713
申请日:2017-03-10
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
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公开(公告)号:US20140228946A1
公开(公告)日:2014-08-14
申请号:US14255179
申请日:2014-04-17
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: Embodiments of an apparatus for treating a deficient mitral valve include an expandable spacer configured for placement between the native leaflets of the mitral valve, the spacer anchorable to a wall of the ventricle. Methods and apparatus for delivering and implanting the prosthetic are also described.
Abstract translation: 用于治疗缺陷型二尖瓣的装置的实施例包括可扩张间隔物,其被配置用于放置在二尖瓣的天然传播片之间,该间隔物可锚定到心室的壁。 还描述了用于递送和植入假体的方法和装置。
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公开(公告)号:US20140214068A1
公开(公告)日:2014-07-31
申请号:US14149637
申请日:2014-01-07
Applicant: Edwards Lifesciences Corporation
Inventor: Yidong M. Zhu , Marlowe E. Patterson , Dan C. Larsen
CPC classification number: A61M25/1029 , A61M25/1002 , A61M2025/1004 , A61M2025/1086 , A61M2025/1088 , B29C49/14 , B29C49/783 , B29C2049/0089 , B29L2031/7543
Abstract: A process for forming a catheter balloon includes subjecting a tubular parison in a mold to molding fluid pressure. The resulting catheter balloon includes a balloon portion having two ends and tubular leg portions extending from either end. The ends of the balloon portion are tapered to the tubular leg portions. While in the mold, the tubular leg portions are drawn axially sufficiently to form permanent creases in the tapered ends. This drawing may be sufficient to cause the material of the tapered ends to exceed the yield strength, particularly with the balloon material in a malleable state. Anomalies on tapered parts of the mold may include ribs or spiral ribs to assist in the creasing process.
Abstract translation: 用于形成导管球囊的方法包括使管型坯在模具中成型流体压力。 所得到的导管球囊包括具有两端的球囊部分和从任一端延伸的管状腿部分。 球囊部分的端部与管状腿部成锥形。 在模具中,管状腿部被轴向拉伸,以在锥形端部形成永久的折痕。 该图可能足以导致锥形端部的材料超过屈服强度,特别是气球材料在可延展状态下。 模具的锥形部分上的异常可以包括肋或螺旋肋,以帮助压痕过程。
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公开(公告)号:US20140012373A1
公开(公告)日:2014-01-09
申请号:US14025701
申请日:2013-09-12
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Oba , David L. Hauser
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: Embodiments of a method for implanting a prosthetic valve at the native mitral valve region of the heart, the prosthetic valve including a main body that is radially compressible to a radially compressed state and self-expandable from the compressed state to a radially expanded state. The prosthetic apparatus also comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body with a leaflet-receiving space between the anchor and an outer surface of the main body to receive a native valve leaflet. Apparatus for delivering and implanting the prosthetic valve are also described.
Abstract translation: 用于在心脏的天然二尖瓣区域植入人工瓣膜的方法的实施例,所述假体瓣膜包括可径向压缩到径向压缩状态并且可从压缩状态自发展到径向扩张状态的主体。 假体装置还包括耦合到主体并且设置在主体外部的至少一个心室锚固体,其具有在锚固体和主体的外表面之间的小叶容纳空间,以接收天然瓣膜小叶。 还描述了用于输送和植入人造瓣膜的装置。
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公开(公告)号:US20230263624A1
公开(公告)日:2023-08-24
申请号:US18137915
申请日:2023-04-21
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: MARK CHAU , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2427 , A61F2/246 , A61F2/2418 , A61F2/2409 , A61F2/2445 , A61F2210/0014 , A61F2220/0008 , A61F2250/006 , A61F2250/0063 , A61F2220/0016 , A61F2230/0069
Abstract: A prosthetic spacer assembly includes a spacer, a first anchor, and a second anchor. The first anchor and the second anchor are each connected to the spacer. The first anchor curves around the spacer when viewed from an upstream end. The second anchor curves around the spacer when viewed from the upstream end.
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公开(公告)号:US11660185B2
公开(公告)日:2023-05-30
申请号:US16713582
申请日:2019-12-13
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/246 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic spacer assembly includes a spacer body, a first anchor, and a second anchor. The first anchor and the second anchor are each connected to the spacer body. The first anchor is configured to capture a first native valve leaflet between the first anchor and the spacer body. The second anchor is configured to capture a second native valve leaflet between the second anchor and the spacer body.
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