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63 条记录 (耗时 0.027 秒)

    Preparation of isoxazole-4,5-dicarboxylic diesters
    22.
    发明授权
    Preparation of isoxazole-4,5-dicarboxylic diesters 失效
    异恶唑-4,5-二羧酸二酯的制备

    公开(公告)号：US5473069A

    公开(公告)日：1995-12-05

    申请号：US667134

    申请日：1991-03-11

    申请人： Thomas Kuekenhoehner ,  Volker Maywald

    发明人： Thomas Kuekenhoehner ,  Volker Maywald

    IPC分类号： C07D261/18 ,  C07D261/12

    CPC分类号： C07D261/18

    摘要： The preparation of isoxazole-4,5-dicarboxylic diester of the formula I ##STR1## where R.sup.1 is any organic radical which is inert under the reaction conditions, and R.sup.2 and R.sup.3 are each alkyl, cycloalkyl or benzyl, entails reacting an aldoxime of the formula II ##STR2## with a diester of maleic or fumaric acid, of the formula IIIR.sup.2 OOC--C.dbd.C--COOR.sup.3 (III)where R.sup.2 and R.sup.3 are identical or different and have the abovementioned meanings, in the presence of an aqueous solution of a hypohalite which is present in excess relative to II.

    摘要翻译： 制备式I（I）的异恶唑-4,5-二羧酸二酯其中R 1是在反应条件下为惰性的任何有机基团，并且R 2和R 3各自为烷基，环烷基或苄基， 式II的醛酮肟与式（III）的马来酸或富马酸的二酯反应，其中R 2和R 3相同或不同并具有上述含义，式III化合物R 2 OOC-C = C-COOR 3（III） 存在相对于II过量存在的次卤酸盐的水溶液。

    Preparation of 3-(2-acyloxyethyl)-dihydro-2(3H)furanones
    23.
    发明授权
    Preparation of 3-(2-acyloxyethyl)-dihydro-2(3H)furanones 失效
    3-（2-酰氧基乙基） - 二氢-2（3H）呋喃酮的制备

    公开(公告)号：US5466831A

    公开(公告)日：1995-11-14

    申请号：US99232

    申请日：1993-07-29

    申请人： Werner Schnurr ,  Rolf Fischer ,  Norbert Goetz ,  Thomas Kuekenhoehner

    发明人： Werner Schnurr ,  Rolf Fischer ,  Norbert Goetz ,  Thomas Kuekenhoehner

    IPC分类号： C07D307/33 ,  C07D307/12

    CPC分类号： C07D307/33

    摘要： A process for the preparation of 3-(2'-acyloxyethyl)-dihydro-2(3H)furanones of the general formula I ##STR1## in which R.sup.1 denotes C.sub.1 -C.sub.12 alkyl, C.sub.5 -C.sub.8 cycloalkyl, aryl, C.sub.7 -C.sub.12 aralkyl, or C.sub.7 -C.sub.12 alkylaryl, in which a 3-(2'-oxyethyl)-dihydro-2(3H)furanone of the general formula II ##STR2## in which R.sup.2 denotes C.sub.1 -C.sub.12 alkyl, C.sub.5 -C.sub.8 cycloalkyl, aryl, C.sub.7 -C.sub.12 aralkyl, or C.sub.7 -C.sub.12 alkylaryl is caused to react with a carboxylic acid, a carboxylic anhydride, and/or an acyl halide in the presence of an acid catalyst at temperatures of from 50.degree. to 250.degree. C. and pressures of from 0.1 to 100 bar.

    摘要翻译： 制备通式I，C5-C8环烷基，芳基，C7-C12芳烷基或C7-C12烷基芳基的3-（2'-酰氧基乙基） - 二氢-2（3H）呋喃酮的方法，其中3 - （2'-氧乙基） - 二氢-2（3H）呋喃酮，其中R 2表示C 1 -C 12烷基，C 5 -C 8环烷基，芳基，C 7 -C 12芳烷基或C 7 -C 12芳烷基， C12烷基芳基在酸催化剂存在下，在50-250℃，压力为0.1-100巴的条件下，与羧酸，羧酸酐和/或酰卤反应。

    Preparation of tetrahydropyran-4-carboxylic acid and esters thereof
    24.
    发明授权
    Preparation of tetrahydropyran-4-carboxylic acid and esters thereof 失效
    四氢吡喃-4-羧酸及其酯的制备

    公开(公告)号：US5371246A

    公开(公告)日：1994-12-06

    申请号：US110219

    申请日：1993-08-23

    申请人： Dirk Borchers ,  Rolf Fischer ,  Norbert Goetz ,  Thomas Kuekenhoehner ,  Werner Schnurr

    发明人： Dirk Borchers ,  Rolf Fischer ,  Norbert Goetz ,  Thomas Kuekenhoehner ,  Werner Schnurr

    IPC分类号： B01J21/04 ,  C07B61/00 ,  C07D309/08 ,  C07D309/06

    CPC分类号： C07D309/08

    摘要： A process for the preparation of tetrahydropyran-4-carboxylic acid and esters thereof of the general formula I ##STR1## in which R.sup.1 denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.5 -C.sub.8 cycloalkyl, or aryl by the reaction of a dihydro-2(3H)furanone of the general formula II ##STR2## in which R.sup.2 denotes hydrogen, C.sub.1 -C.sub.6 alkyl, or --CO--R.sup.3 andR.sup.3 denotes hydrogen or C.sub.1 -C.sub.6 alkyl, with water or an alcohol of the general formula IIIR.sup.1 --OH (III),in whichR.sup.1 has the aforementioned meaning,at temperatures ranging from 200.degree. to 350.degree. C. in the presence of a heterogenous acid catalyst, in which use is made of a fixed heterogenous acid catalyst.

    摘要翻译： 制备通式I的四氢吡喃-4-羧酸及其酯的方法，其中R 1表示氢，C 1 -C 6烷基，C 5 -C 8环烷基或芳基，其中二氢 -2（3H）呋喃酮，其中R 2表示氢，C 1 -C 6烷基或-CO-R 3，R 3表示氢或C 1 -C 6烷基，其中R 2表示氢或C 1 -C 6烷基， 在异种酸催化剂的存在下，在200〜350℃的温度范围内，通式III的R1-OH（Ⅲ），其中R 1具有上述含义，其中使用固定的异种酸催化剂。

    Preparation of 3-carbamoylisoxazole-4-carboxylic esters by selective amidation
    25.
    发明授权
    Preparation of 3-carbamoylisoxazole-4-carboxylic esters by selective amidation 失效
    通过选择性酰胺化制备3-氨基甲酰基异恶唑-4-羧酸酯

    公开(公告)号：US5276160A

    公开(公告)日：1994-01-04

    申请号：US35660

    申请日：1993-03-23

    申请人： Volker Maywald ,  Thomas Kuekenhoehner ,  Gerhard Hamprecht

    发明人： Volker Maywald ,  Thomas Kuekenhoehner ,  Gerhard Hamprecht

    IPC分类号： C07D261/18 ,  C07D413/04 ,  C07D261/08

    CPC分类号： C07D261/18

    摘要： Abstract of the Disclosure: 3-Carbamoylisoxazole-4-carboxylic esters of the formula I ##STR1## where R.sup.1 is hydrogen, alkyl, cycloalkyl, phenyl or a 5- to 6-membered heterocyclic radical, it being possible for the organic radicals to carry substituents which are inert under the reaction conditions;R.sup.2 is alkyl, cycloalkyl, benzyl or C.sub.1 -C.sub.3 -alkenyl;R.sup.3 is hydrogen, alkyl or cycloalkyl andR.sup.4 is an aliphatic or cycloaliphatic radical or unsubstituted or substituted phenyl, or R.sup.4 together with R.sup.3 is a 4- to 7-membered alkylene chain which can be interrupted by oxygen, sulfur or N-methyl, are prepared by selective amidation of an isoxazole-3,4-dicarboxylic diester of the formula II ##STR2## where R.sup.2 has the meanings of R.sup.2 and is identical to or different from R.sup.2.

    摘要翻译： 本发明摘要：式I的3-氨基甲酰异恶唑-4-羧酸酯其中R 1是氢，烷基，环烷基，苯基或5-至6-元杂环基，有机基团可能 携带在反应条件下为惰性的取代基; R2是烷基，环烷基，苄基或C1-C3-烯基; R3是氢，烷基或环烷基，R4是脂族或脂环族基团或未取代或取代的苯基，或R4与R3一起可以被氧，硫或N-甲基中断的4至7元亚烷基链， 通过选择性酰胺化式II的异恶唑-3,4-二羧酸二酯，其中R 2具有R 2的含义并且与R 2相同或不同。

    Preparation of isoxazole-3,4-dicarboxylic acid derivatives
    26.
    发明授权
    Preparation of isoxazole-3,4-dicarboxylic acid derivatives 失效
    异恶唑-3,4-二羧酸衍生物的制备

    公开(公告)号：US5264580A

    公开(公告)日：1993-11-23

    申请号：US39573

    申请日：1993-03-23

    申请人： Volker Maywald ,  Thomas Kuekenhoehner ,  Peter Muenster ,  Stefan Stahl

    发明人： Volker Maywald ,  Thomas Kuekenhoehner ,  Peter Muenster ,  Stefan Stahl

    IPC分类号： C07D261/18 ,  C97D261/08

    CPC分类号： C07D261/18

    摘要： A process for preparing isoxazole-3,4-dicarboxylic acid derivatives of the formula I ##STR1## where R.sup.1 is hydrogen, alkyl, cycloalkyl or phenyl, or a 5- to 6-membered heterocyclic radical, and the organic radicals can have substituents which are inert under the reaction conditions;R.sup.2 is hydrogen, alkyl, cycloalkyl, benzyl or C.sub.3 -C.sub.6 -alkenyl;A is NR.sup.3 R.sup.4 where R.sup.3 is hydrogen or an aliphatic or cycloaliphatic radical and R.sup.4 is an aliphatic or cycloaliphatic radical or unsubstituted or substituted phenyl, or R.sup.3 forms together with R.sup.4 a 4- to 7-membered alkylene chain which can be interrupted by oxygen, sulfur or N-methyl, or is OR.sup.5 where R.sup.5 is alkyl, cycloalkyl, benzyl or alkenyl;by deprotonation of a CH-acid compound of the formula II ##STR2## using a base and reacting with hydroximyl chlorides of the formula III ##STR3## wherein a magnesium alcoholate of the formula IVMg(OR.sup.6 ).sub.2 IVwhere R.sup.6 is an aliphatic or cycloaliphatic radical is used for the deprotonation.

    摘要翻译： 制备式I的异恶唑-3,4-二羧酸衍生物，其中R1是氢，烷基，环烷基或苯基，或5-至6-元杂环基，并且有机基团可以具有取代基 在反应条件下是惰性的; R2是氢，烷基，环烷基，苄基或C3-C6-烯基; A是NR 3 R 4，其中R 3是氢或脂族或脂环族基团，R 4是脂族或脂环族基团或未取代或取代的苯基，或R 3与R 4一起形成可被氧，硫中断的4-至7-元亚烷基链 或N-甲基，或是OR 5，其中R 5是烷基，环烷基，苄基或烯基; 通过使用碱将式II II的CH-酸化合物去质子化，并与式III的氢氯化物反应，其中式IV的醇镁盐（OR 6）2 IV，其中R 6是 脂肪族或脂环族基团用于去质子化。

    Carboxamides
    29.
    发明授权
    Carboxamides 失效

    公开(公告)号：US5201932A

    公开(公告)日：1993-04-13

    申请号：US877365

    申请日：1992-05-04

    申请人： Volker Maywald ,  Wolfgang Freund ,  Gerhard Hamprecht ,  Thomas Kuekenhoehner ,  Peter Plath ,  Bruno Wuerzer ,  Karl-Otto Westphalen

    发明人： Volker Maywald ,  Wolfgang Freund ,  Gerhard Hamprecht ,  Thomas Kuekenhoehner ,  Peter Plath ,  Bruno Wuerzer ,  Karl-Otto Westphalen

    IPC分类号： A01N43/80 ,  C07D261/18 ,  C07D275/02 ,  C07D275/03

    CPC分类号： C07D275/03 ,  A01N43/80 ,  C07D261/18

    摘要： Carboxamides Ia, Ib, Ic and Id ##STR1## (X=O, S; R.sup.1 =H, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted benzyl, alkoxy, alkylthio, haloalkoxy, haloalkylthio, substituted or unsubstituted phenyl, substituted or unsubstituted phenoxy or phenylthio, a substituted or unsubstituted 5- or 6-membered heterocyclic radical containing one or two heteroatoms, cycloalkyl-substituted alkyl, substituted or unsubstituted alkenyl which may be epoxidized, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl or cycloalkenyl; R.sup.1 '=cycloalkyl-substituted alkyl, substituted or unsubstituted alkenyl which may be epoxidized, substituted or unsubstituted cycloalkenyl; R.sup.2 =CHO, 4,5-dihydrooxazol-2-yl, COYR.sup.5, CONR.sup.6 R.sup.7 ; Y=O, S; R.sup.5 =H, substituted or unsubstituted alkyl, cycloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted phenyl, a 5- or 6-membered heterocyclic radical containing up to 3 heteroatoms, benzotriazole, N-phthalimido, tetrahydrophthalimido, succinimido, maleiimido, 2,2-dimethyl-1,3-dioxolan-4-ylmethyl, 1,3-dioxolan-2-on-4-ylmethyl, and when Y.dbd.O: one equivalent of a cation from the group of the alkali or alkaline earth metals, Mn, Cu, Fe ammonium and substituted ammonium, a radical --N.dbd.CR.sup.8 R.sup.9 or --W--Z; R.sup.8, R.sup.9 .dbd.H, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, cycloalkyl, alkoxy, furanyl, substituted or unsubstituted phenyl; R.sup.8 +R.sup.9 =4-7-membered methylene chain; W=alkylene chain, ethoxyethylene chain, butylene, butynylene chain; Z=a molecular moiety bonded to W in the .omega.-position and is the same as that linked to W in the .alpha.-position of W; R.sup.6 .dbd.H, alkyl, cycloalkyl; R.sup.7 .dbd.H; alkyl; --C(O-alkyl).dbd.N--H or --(O--alkyl).dbd.N--alkyl; R.sup.6 +R.sup.7 =4-5-membered methylene chain; R.sup.3 .dbd.H, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl; R.sup.4 .dbd.H, OH, alkoxy, subsituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, di-(C.sub.1 -C.sub.4)-alkylamino, a substituted or unsubstituted 5- or 6-membered heterocyclic radical containing one or two heteroatoms, substituted or unsubstituted phenyl, substituted or unsubstituted naphthyl; R.sub.3 +R.sub.4 =4-7-membered methylene chain which may be interrupted by O, S or N--CH.sub.3, or --(CH.sub.2).sub.3 --CO--)and their environmentally tolerated salts.The compounds Ia to Id are suitable as herbicides.