摘要:
A lipoprotein adsorbent for use in extracorporeal circulation treatment which is made of a water-insoluble porous hard gel which has an exclusion limit value from 10.sup.6 to 10.sup.9 measured by using glubular proteins and comprises a polymer having hydroxy group in at least a part of the molecule, at least a part of hydroxy groups on the surface of said gel being converted to sulfates. By using the adsorbent of the present invention, LDL and VLDL can be selectively and effectively removed from the body fluids of the patient. Further, the adsorbent of the present invention can be prepared in a lower cost than the adsorbent based on the principle of the affinity chromatography, in which a relatively expensive ligand is employed.
摘要:
An adsorbent for removing low and/or very low density lipoprotein from body fluid in extracorporeal circulation treatment, which comprises a water-insoluble porous hard gel with exclusion limit of 10.sup.6 to 10.sup.9 daltons on which a sulfated compound is immobilized by a covalent linkage.
摘要:
The present invention relates to an information processing apparatus with improved operatability. With the information processing apparatus in which the user is capable of watching a television program and connecting to the Internet, the index panel 1 shows channel buttons 2 to be operated to select a desired program, a site button 71 to be operated to make an access to site A available on the Internet and a site button 72 to be operated to make an access to site B on the Internet. The present invention allows the user to watch a television program and can be applied to an information processing apparatus such as a personal computer, which can be connected to the Internet.
摘要:
The invention makes it possible to draw lots for a present in real time in association with a broadcast program. A broadcasting station broadcasts information relating to lot for a present that is associated with a broadcast program by superimposing it on a video signal in vertical blanking intervals. The lot information is decoded by a decoder and viewed by a viewer on a TV receiver. When the viewer commands the decoder to enter the lot for the present, the decoder accesses a present call center and an automatic lots-drawing system draws lots. A drawing result is transmitted to the broadcasting station and announced during the broadcast of the program. A sponsor sends the present product to winner viewers based on winner data.
摘要:
An information processing apparatus with improved operatability in which the user is capable of watching a television program and connecting to the Internet. An index panel shows channel buttons operated to select a desired program, a first site button provides access to site A available on the Internet and a second site button provides access to site B on the Internet. The user is able to watch a television program and can have access to an information processing apparatus such as a personal computer, which can be connected to the Internet.
摘要:
There is provided a method for immobilizing a ligand by reacting a solvent-insoluble carrier having aldehyde group with a compound shown by the general formula: ##STR1## wherein X is --S-- or --O--, R.sup.1, R.sup.2 and R.sup.6 are the same or different, each of which is hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R.sup.3 is hydrogen atom or a substituent wherein an atom adjacent to nitrogen atom shown in the above-mentioned general formula has no unsaturated bond, R.sup.4, R.sup.5 and R.sup.7 are arbitrary substituents; provided that only one partial chemical structure of HX--C--C--NHR.sup.3 wherein X and R.sup.3 are the same as defined above or HX--C--C--C--NHR.sup.3 wherein X and R.sup.3 are the same as defined above is contained in one compound described above by which, a ligand or a compound to which a ligand is bonded can react specifically and effectively with aldehyde group in a solvent-insoluble carrier at a prescribed position to form a stable bond.
摘要:
An adsorbent for .beta..sub.2 -microglobulin and immunoglobulin L-chain suitable for use in an extracorporeal circulation treatment, which comprises a porous water-insoluble carrier and a compound immobilized onto said carrier, said compound satisfying that the value of log P, in which P is a partition coefficient in an octanol-water system, is not less than 2.5. The adsorbent is inexpensive, and efficiently adsorb and remove .beta..sub.2 -microglobulin and immunoglobulin L-chain contained in a body fluid.
摘要:
A method for treating circulatory fluid constituents with an apparatus which includes a first switching device which connects the upstream side of a first circulatory fluid treatment device with a flow of circulatory fluid from a source, and a second switching device which connects the downstream side of the first circulatory fluid treatment device with a destination of the circulatory fluid. Next, the second switching device maintains the flow of circulatory fluid to the destination from the downstream side of the first circulatory fluid treatment device, the upstream side of the first circulatory fluid treatment device is disconnected with the flow of circulatory fluid from the source, and further a third switching device connects the upstream side of a second circulatory fluid treatment device to the flow of a circulatory fluid from the source, and a fourth switching device connects the downstream side of the second circulatory fluid treatment device to communicate with the upstream side of the first circulatory fluid treatment device. Finally, the third switching device maintains the flow of circulatory fluid from the source into the upstream side of the second circulatory fluid treatment device, the downstream side of the first circulatory fluid treatment device is disconnected from sending the flow of circulatory fluid to the destination, and a fifth switching device connects the downstream side of the second circulatory fluid treatment device with the destination for the flow of circulatory fluid thereto.
摘要:
A lipoprotein adsorbent for use in extracorporeal circulation treatment which is made of a water-insoluble porous hard gel which has an exclusion limit value from 10.sup.6 to 10.sup.9 measured by using glubular proteins and comprises a polymer having hydroxy group in at least a part of the molecule, at least a part of hydroxy groups on the surface of said gel being converted to sulfates. By using the adsorbent of the present invention, LDL and VLDL can be selectively and effectively removed from the body fluids of the patient. Further, the adsorbent of the present invention can be prepared in a lower cost than the adsorbent based on the principle of the affinity chromatography, in which a relatively expensive ligand is employed.
摘要:
Adsorbent for removing a harmful substance to be removed from body fluid such as blood or plasma composed of a porous hard gel on which a ligand having an affinity for the harmful substance is immobilized. The adsorbent is suitable for selective removal of harmful substances such as VLDL, LDL, harmful proteins, viruses and harmful cells, in extracorporeal circulation treatment.