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21.发明授权Implantable cardioverter defibrillator designed for use in a magnetic resonance imaging environment 有权设计用于磁共振成像环境的植入式心律转复除颤器公开(公告)号：US09101782B2
公开(公告)日：2015-08-11
申请号：US13958582
申请日：2013-08-04
Applicant: Greatbatch Ltd.
Inventor： Dominick J. Frustaci , Barry C. Muffoletto , Robert A. Stevenson
CPC classification number: A61N1/3987 , A61B5/0555 , A61N1/3718 , A61N1/3925 , A61N1/3962
Abstract: An implantable cardioverter defibrillator includes a communication interface operable to receive a communication signal from an external programmer. The communication signal includes a command to switch the ICD from a first mode to a second mode. A processor is in electrical communication with the communication interface and configured to switch the ICD between the first and second modes. A battery is configured to supply low DC voltage. A converter is configured to convert the low DC voltage to a high DC voltage. An energy storage capacitor is electrically coupled to the converter and configured to store a therapeutic energy or high DC voltage including at least 15 joules. The second mode includes activating the converter to convert the low DC voltage to the high DC voltage and storing the therapeutic energy or at least 15 joules within the energy storage capacitor during a period of time of the second mode.
Abstract translation: 植入式心律转复除颤器包括可操作以从外部编程器接收通信信号的通信接口。 通信信号包括将ICD从第一模式切换到第二模式的命令。 处理器与通信接口电通信并且被配置为在第一和第二模式之间切换ICD。 电池配置为提供低直流电压。 A转换器被配置为将低DC电压转换成高DC电压。 储能电容器电耦合到转换器并且被配置为存储包括至少15焦耳的治疗能量或高DC电压。 第二模式包括在第二模式的时间段期间激活转换器以将低DC电压转换为高DC电压并将能量存储电容器中的治疗能量或至少15焦耳存储。
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22.发明申请EMI Filtered Co-Connected Hermetic Feedthrough, Feedthrough Capacitor and Leadwire Assembly for an Active Implantable Medical Device 有权电磁干扰过滤联合密封馈通，馈通电容器和有源可植入医疗设备的导线组件公开(公告)号：US20140036409A1
公开(公告)日：2014-02-06
申请号：US13743276
申请日：2013-01-16
Applicant: GREATBATCH LTD.
Inventor： Robert A. Stevenson , Thomas Marzano , Keith W. Seitz , Steven W. Winn , Christine A. Frysz , Richard L. Brendel , Jason Woods , Dominick J. Frustaci , Xiaohong Tang , William C. Thiebolt
IPC: H01G4/35
CPC classification number: A61N1/3754 , A61N1/05 , A61N1/08 , A61N1/372 , A61N1/375 , B23K35/3013 , C22C29/12 , H01G2/103 , H01G4/005 , H01G4/12 , H01G4/30 , H01G4/35 , H01G4/40 , H01R43/00 , H02G3/22 , Y10T156/1052
Abstract: A co-connected hermetic feedthrough, feedthrough capacitor, and leadwire assembly includes a dielectric substrate with a via hole disposed through the dielectric substrate from a body fluid side to a device side. A conductive fill is disposed within the via forming a hermetic seal and is electrically conductive between the body fluid side and the device side. A feedthrough capacitor is attached to the dielectric substrate and includes a capacitor dielectric substrate, an unfilled capacitor via hole including an inner metallization, a set of capacitor active electrode plates electrically coupled to the inner metallization, an outer metallization disposed and a set of capacitor ground electrode plates electrically coupled to the outer metallization. A conductive leadwire is disposed within the unfilled capacitor via hole. An electrical joint connects the conductive fill, the capacitor inner metallization along with the capacitor active electrode plates and the conductive leadwire.
Abstract translation: 一个共同连接的密封馈通电源，馈通电容器和引线组件包括具有通孔的电介质基片，其通过介电基片从体液侧设置到器件侧。 导电填料设置在通孔内形成气密密封，并且在体液侧和装置侧之间导电。 馈通电容器附接到电介质基板，并且包括电容器电介质基板，包括内部金属化的未填充的电容器通孔，电耦合到内部金属化的一组电容器有源电极板，设置的外部金属化和一组电容器接地 电极板电耦合到外部金属化。 导电引线设置在未填充的电容器通孔内。 电接头将导电填充物，电容器内部金属化以及电容器有源电极板和导电引线连接。
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公开(公告)号：US20130226262A1
公开(公告)日：2013-08-29
申请号：US13858268
申请日：2013-04-08
Applicant: Greatbatch Ltd.
Inventor： Robert A. Stevenson , Christine A. Frysz , Barry C. Muffoletto , Robert W. Siegler , Steven W. Winn , Thomas A. Skwara , Dominick J. Frustaci
IPC: A61N1/36
CPC classification number: A61N1/36135 , A61N1/36082 , A61N1/37282 , A61N1/37288
Abstract: Deep brain electrodes are remotely sensed and activated by means of a remote active implantable medical device (AIMD). In a preferred form, a pulse generator is implanted in the pectoral region and includes a hermetic seal through which protrudes a conductive leadwire which provides an external antenna for transmission and reception of radio frequency (RF) pulses. One or more deep brain electrode modules are constructed and placed which can transmit and receive RF energy from the pulse generator. An RF telemetry link is established between the implanted pulse generator and the deep brain electrode assemblies. The satellite modules are configured for generating pacing pulses for a variety of disease conditions, including epileptic seizures, Turrets Syndrome, Parkinson's Tremor, and a variety of other neurological or brain disorders.
Abstract translation: 通过远程有源可植入医疗设备（AIMD）远程感测和激活深脑电极。 在优选形式中，脉冲发生器被植入胸部区域并且包括气密密封，通过该气密密封件突出提供用于射频（RF）脉冲的发射和接收的外部天线的导电引线。 一个或多个深脑电极模块被构造和放置，其可以从脉冲发生器发射和接收RF能量。 在植入的脉冲发生器和深脑电极组件之间建立RF遥测链路。 卫星模块被配置用于产生用于各种疾病状况的起搏脉冲，包括癫痫发作，炮塔综合征，帕金森氏颤颤和各种其他神经或脑部疾病。
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24.发明授权公开(公告)号：US11202916B2
公开(公告)日：2021-12-21
申请号：US16656775
申请日：2019-10-18
Applicant: Greatbatch Ltd.
Inventor： Dominick J. Frustaci , Keith W. Seitz , Thomas Marzano , Robert A. Stevenson , Christine A. Frysz , Richard L. Brendel , Jason Woods
IPC: A61N1/375 , H01G4/35 , H01R13/7195 , H01G2/22 , H01G2/10 , A61N1/08 , H01G4/40 , A61N1/05 , H05K1/02
Abstract: A hermetically sealed filtered feedthrough for an active implantable medical device includes a first conductive leadwire extending from a first end to a second end, the first leadwire second end extending outwardly beyond the device side of an insulator hermetically sealed to a ferrule for the feedthrough. A circuit board supporting a chip capacitor is disposed adjacent to a device side of the insulator and has a circuit board passageway. The first leadwire first end resides in the circuit board passageway. A second conductive leadwire on the device side has a second leadwire first end disposed in the circuit board passageway with a second leadwire second end extending outwardly beyond the circuit board to be connectable to AIMD internal electronics. The second leadwire first end is connected to the first leadwire first end and a capacitor internal metallization in the circuit board passageway. The circuit board further comprises a ground electrode plate that is connected to the ground termination of the chip capacitor and to the ferrule.
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公开(公告)号：US09511220B2
公开(公告)日：2016-12-06
申请号：US14600401
申请日：2015-01-20
Applicant: Greatbatch Ltd.
Inventor： Thomas Marzano , Keith W. Seitz , Robert A. Stevenson , Xiaohong Tang , William C. Thiebolt , Christine A. Frysz , Richard L. Brendel , Jason Woods , Steven W. Winn , Dominick J. Frustaci , Bruehl E. Truex , Donald H. Hickel, Jr.
IPC: A61N1/00 , A61N1/08 , A61N1/05 , H01G4/35 , H01G2/10 , H01R43/00 , H01G4/005 , H01G4/12 , H01G4/40 , H02G3/22 , A61N1/372 , A61N1/375 , C22C29/12
CPC classification number: A61N1/3754 , A61N1/05 , A61N1/08 , A61N1/372 , A61N1/375 , B23K35/3013 , C22C29/12 , H01G2/103 , H01G4/005 , H01G4/12 , H01G4/30 , H01G4/35 , H01G4/40 , H01R43/00 , H02G3/22 , Y10T156/1052
Abstract: An elevated feedthrough is attachable to a top or a side of an active implantable medical device. The feedthrough includes a conductive ferrule and a dielectric substrate. The dielectric substrate is defined as comprising a body fluid side and a device side disposed within the conductive ferrule. The dielectric substrate includes a body fluid side elevated portion generally raised above the conductive ferrule. At least one via hole is disposed through the dielectric substrate from the body fluid side to the device side. A conductive fill is disposed within the at least one via hole forming a hermetic seal and electrically conductive between the body fluid side and the device side. A leadwire connection feature is on the body fluid side electrically coupled to the conductive fill and disposed adjacent to the elevated portion of the dielectric substrate.
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Patent Agency Ranking
26.发明授权Implantable cardioverter defibrillator designed for use in a magnetic resonance imaging environment 有权设计用于磁共振成像环境的植入式心律转复除颤器公开(公告)号：US09504843B2
公开(公告)日：2016-11-29
申请号：US14796154
申请日：2015-07-10
Applicant: Greatbatch Ltd.
Inventor： Dominick J. Frustaci , Robert A. Stevenson , Barry C. Muffoletto
CPC classification number: A61N1/3987 , A61B5/044 , A61B5/0452 , A61B5/055 , A61B5/0555 , A61B5/14542 , A61B5/742 , A61B5/746 , A61N1/3718 , A61N1/3925 , A61N1/3956 , A61N1/3962
Abstract: An implantable cardioverter defibrillator (ICD) includes a communication interface operable to receive a communication signal from an external programmer. With the ICD not being in the presence of an MRI field generated by an MRI scanner, a communication signal is sent precharging a high energy storage capacitor before the patient undergoes the MRI scan. The signal also switches the ICD into an MRI mode which turns off the ICD's sensing functions detecting a dangerous ventricular arrhythmia. An operator monitors the patient's vital signs with sensors connected to the patient. If the patient does require the defibrillation shock, the operator sends a second communication signal delivering the defibrillation shock from the precharged high energy storage capacitor of the ICD. The patient can then be removed from the MRI scanner and the RF and gradient fields of the MRI scanner turned off.
Abstract translation: 植入式心律转复除颤器（ICD）包括可操作以从外部编程器接收通信信号的通信接口。 在ICD不存在由MRI扫描仪产生的MRI场的情况下，在患者进行MRI扫描之前，通信信号被预先充电高能量存储电容器。 该信号还将ICD切换到MRI模式，其将ICD的感测功能关闭以检测危险的室性心律失常。 操作员通过连接到患者的传感器监测患者的生命体征。 如果患者确实需要除颤电击，则操作者从ICD的预充电高能量存储电容器发送递送除颤电击的第二通信信号。 然后可以从MRI扫描仪中取出患者，并关闭MRI扫描仪的RF和梯度场。
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27.发明申请公开(公告)号：US20150314132A1
公开(公告)日：2015-11-05
申请号：US14796154
申请日：2015-07-10
Applicant: Greatbatch Ltd.
Inventor： Dominick J. Frustaci , Robert A. Stevenson , Barry C. Muffoletto
CPC classification number: A61N1/3987 , A61B5/044 , A61B5/0452 , A61B5/055 , A61B5/0555 , A61B5/14542 , A61B5/742 , A61B5/746 , A61N1/3718 , A61N1/3925 , A61N1/3956 , A61N1/3962
Abstract: An implantable cardioverter defibrillator (ICD) includes a communication interface operable to receive a communication signal from an external programmer. With the ICD not being in the presence of an MRI field generated by an MRI scanner, a communication signal is sent precharging a high energy storage capacitor before the patient undergoes the MRI scan. The signal also switches the ICD into an MRI mode which turns off the ICD's sensing functions detecting a dangerous ventricular arrhythmia. An operator monitors the patient's vital signs with sensors connected to the patient. If the patient does require the defibrillation shock, the operator sends a second communication signal delivering the defibrillation shock from the precharged high energy storage capacitor of the ICD. The patient can then be removed from the MRI scanner and the RF and gradient fields of the MRI scanner turned off.
Abstract translation: 植入式心律转复除颤器（ICD）包括可操作以从外部编程器接收通信信号的通信接口。 在ICD不存在由MRI扫描仪产生的MRI场的情况下，在患者进行MRI扫描之前，通信信号被预先充电高能量存储电容器。 该信号还将ICD切换到MRI模式，其将ICD的感测功能关闭以检测危险的室性心律失常。 操作员通过连接到患者的传感器监测患者的生命体征。 如果患者确实需要除颤电击，则操作者从ICD的预充电高能量存储电容器发送递送除颤电击的第二通信信号。 然后可以从MRI扫描仪中取出患者，并关闭MRI扫描仪的RF和梯度场。
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28.发明申请公开(公告)号：US20150134039A1
公开(公告)日：2015-05-14
申请号：US14600401
申请日：2015-01-20
Applicant: Greatbatch Ltd.
Inventor： Thomas Marzano , Keith W. Seitz , Robert A. Stevenson , Xiaohong Tang , William C. Thiebolt , Christine A. Frysz , Richard L. Brendel , Jason Woods , Steven W. Winn , Dominick J. Frustaci , Bruehl E. Truex , Donald H. Hickel, JR.
CPC classification number: A61N1/3754 , A61N1/05 , A61N1/08 , A61N1/372 , A61N1/375 , B23K35/3013 , C22C29/12 , H01G2/103 , H01G4/005 , H01G4/12 , H01G4/30 , H01G4/35 , H01G4/40 , H01R43/00 , H02G3/22 , Y10T156/1052
Abstract: An elevated feedthrough is attachable to a top or a side of an active implantable medical device. The feedthrough includes a conductive ferrule and a dielectric substrate. The dielectric substrate is defined as comprising a body fluid side and a device side disposed within the conductive ferrule. The dielectric substrate includes a body fluid side elevated portion generally raised above the conductive ferrule. At least one via hole is disposed through the dielectric substrate from the body fluid side to the device side. A conductive fill is disposed within the at least one via hole forming a hermetic seal and electrically conductive between the body fluid side and the device side. A leadwire connection feature is on the body fluid side electrically coupled to the conductive fill and disposed adjacent to the elevated portion of the dielectric substrate.
Abstract translation: 升高的馈通可附接到有源可植入医疗装置的顶部或侧面。 馈通包括导电套圈和电介质基片。 电介质基板被定义为包括体液侧和设置在导电套圈内的器件侧。 电介质基片包括通常在导电套圈上方升高的体液侧提升部分。 至少一个通孔穿过电介质基底从体液侧设置到器件侧。 导电填料设置在至少一个通孔内，形成气密密封并在体液侧和装置侧之间导电。 引线连接特征在体液侧电耦合到导电填充物并且邻近电介质基底的升高部分设置。
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29.发明授权Capacitor for an active implantable medical device (AIMD) for handling high RF power induced in an implanted lead from an external RF field 有权用于处理来自外部RF场的植入引线中感应的高RF功率的有源植入式医疗设备（AIMD）的电容器公开(公告)号：US08855768B1
公开(公告)日：2014-10-07
申请号：US14088849
申请日：2013-11-25
Applicant: Greatbatch Ltd.
Inventor： Robert Shawn Johnson , Dominick J. Frustaci , Warren S. Dabney , Robert A. Stevenson , Keith W. Seitz , Christine A. Frysz , Thomas Marzano , Richard L. Brendel , John E. Roberts , William Thiebolt , Christopher M. Williams , Jason Woods , Buehl E. Truex
CPC classification number: A61N1/08 , A61N1/05 , A61N1/3718 , A61N1/3754 , H01G4/35 , H03H1/0007
Abstract: An RF filter for an active medical device (AMD), for handling RF power induced in an associated lead from an external RF field at a selected MRI frequency or range frequencies includes a capacitor having a capacitance of between 100 and 10,000 picofarads, and a temperature stable dielectric having a dielectric constant of 200 or less and a temperature coefficient of capacitance (TCC) within the range of plus 400 to minus 7112 parts per million per degree centigrade. The capacitor's dielectric loss tangent in ohms is less than five percent of the capacitor's equivalent series resistance (ESR) at the selected MRI RF frequency or range of frequencies.
Abstract translation: 用于在选定的MRI频率或范围频率处理来自外部RF场的相关引线中感应的RF功率的用于主动医疗装置（AMD）的RF滤波器包括具有100至10,000皮法之间的电容的电容器，以及温度 介电常数为200以下，电容温度系数（TCC）在400〜71212ppm /摄氏度范围内的稳定电介质。 电容器的介电损耗角正切欧姆小于所选MRI射频频率或频率范围内电容器等效串联电阻（ESR）的百分之五。
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公开(公告)号：US08792987B2
公开(公告)日：2014-07-29
申请号：US13858268
申请日：2013-04-08
Applicant: Greatbatch Ltd.
Inventor： Robert A. Stevenson , Christine A. Frysz , Barry C. Muffoletto , Robert W. Siegler , Steven W. Winn , Thomas A. Skwara , Dominick J. Frustaci
CPC classification number: A61N1/36135 , A61N1/36082 , A61N1/37282 , A61N1/37288
Abstract: Deep brain electrodes are remotely sensed and activated by means of a remote active implantable medical device (AIMD). In a preferred form, a pulse generator is implanted in the pectoral region and includes a hermetic seal through which protrudes a conductive leadwire which provides an external antenna for transmission and reception of radio frequency (RF) pulses. One or more deep brain electrode modules are constructed and placed which can transmit and receive RF energy from the pulse generator. An RF telemetry link is established between the implanted pulse generator and the deep brain electrode assemblies. The satellite modules are configured for generating pacing pulses for a variety of disease conditions, including epileptic seizures, Turrets Syndrome, Parkinson's Tremor, and a variety of other neurological or brain disorders.
Abstract translation: 通过远程有源可植入医疗设备（AIMD）远程感测和激活深脑电极。 在优选形式中，脉冲发生器被植入胸部区域并且包括气密密封，通过该气密密封件突出提供用于射频（RF）脉冲的发射和接收的外部天线的导电引线。 一个或多个深脑电极模块被构造和放置，其可以从脉冲发生器发射和接收RF能量。 在植入的脉冲发生器和深脑电极组件之间建立RF遥测链路。 卫星模块被配置用于产生用于各种疾病状况的起搏脉冲，包括癫痫发作，炮塔综合征，帕金森氏颤颤和各种其他神经或脑部疾病。
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