Optimizing virtual slide image quality
    21.
    发明授权
    Optimizing virtual slide image quality 有权
    优化虚拟幻灯片图像质量

    公开(公告)号:US08805050B2

    公开(公告)日:2014-08-12

    申请号:US13355245

    申请日:2012-01-20

    IPC分类号: G06K9/00 G06K9/40

    摘要: Systems and methods for assessing and optimizing virtual microscope slide image quality are provided. In order to determine whether any of multiple virtual slide images has an out of focus area and is therefore a candidate for manual inspection or rescanning, various focus points used to scan each virtual slide image are used to calculate a best fit surface for each virtual slide image. The best fit surface is then used to determine whether any of the various focus points are outliers. If it is determined that a virtual slide image is associated with outlying focus points, it is identified as a candidate for manual inspection or rescanning.

    摘要翻译: 提供了评估和优化虚拟显微镜载玻片图像质量的系统和方法。 为了确定多个虚拟幻灯片图像中的任何一个是否具有失焦区域,因此是用于手动检查或重新扫描的候选者,用于扫描每个虚拟幻灯片图像的各种对焦点用于为每个虚拟幻灯片计算最佳拟合曲面 图片。 然后使用最佳拟合曲面来确定各个焦点中是否有异常值。 如果确定虚拟幻灯片图像与外围焦点相关联,则将其识别为手动检查或重新扫描的候选者。

    Optimizing virtual slide image quality
    22.
    发明授权
    Optimizing virtual slide image quality 有权
    优化虚拟幻灯片图像质量

    公开(公告)号:US08103082B2

    公开(公告)日:2012-01-24

    申请号:US12711157

    申请日:2010-02-23

    IPC分类号: G06K9/00 G06K9/40

    摘要: Systems and methods for assessing and optimizing virtual microscope slide image quality are provided. In order to determine whether a virtual slide image has any out of focus areas and is therefore a candidate for manual inspection, the various focus points used to scan the virtual slide image are used to calculate a best fit surface for the virtual slide image. The distance of each focus point from the best fit surface is then calculated and the largest distance is compared to a predetermined value. If the largest distance from a focus point to the best fit surface is larger than the predetermined value, then the virtual slide image is designated as needing a manual inspection and possible re-scan.

    摘要翻译: 提供了评估和优化虚拟显微镜载玻片图像质量的系统和方法。 为了确定虚拟幻灯片图像是否具有任何偏离焦点区域,因此是用于手动检查的候选者,用于扫描虚拟幻灯片图像的各种对焦点用于计算虚拟幻灯片图像的最佳拟合曲面。 然后计算每个对焦点与最佳拟合表面的距离,并将最大距离与预定值进行比较。 如果从焦点到最佳配合曲面的最大距离大于预定值,则虚拟幻灯片图像被指定为需要手动检查和可能的重新扫描。

    STANDARDIZING FLUORESCENCE MICROSCOPY SYSTEMS
    25.
    发明申请
    STANDARDIZING FLUORESCENCE MICROSCOPY SYSTEMS 有权
    标准化荧光显微系统

    公开(公告)号:US20140226866A1

    公开(公告)日:2014-08-14

    申请号:US14232575

    申请日:2012-07-12

    IPC分类号: G06T7/00 G01N21/64

    摘要: Systems and methods for standardizing one or more fluorescence scanning instruments to a reference system by separating the effects of drift and normalization. In an embodiment, a drift image comprising an image of a drift reference slide is captured by a system to be standardized. A drift measurement is calculated using the drift image. A first normalization image comprising an image of a normalization slide is also captured by the system to be standardized. A reference normalization image, also comprising an image of the normalization slide, is captured by a reference system. The first normalization image is compared to the reference normalization image to determine a gamma value and offset value for the system to be standardized.

    摘要翻译: 通过分离漂移和归一化的影响将一个或多个荧光扫描仪器标准化到参考系统的系统和方法。 在一个实施例中,包括漂移参考滑块的图像的漂移图像由待标准化的系统捕获。 使用漂移图像计算漂移测量。 包括标准化幻灯片的图像的第一标准化图像也被要标准化的系统捕获。 还包括归一化幻灯片的图像的参考归一化图像由参考系统捕获。 将第一归一化图像与参考归一化图像进行比较,以确定要标准化的系统的伽马值和偏移值。

    Optimizing Virtual Slide Image Quality
    26.
    发明申请
    Optimizing Virtual Slide Image Quality 有权
    优化虚拟幻灯片图像质量

    公开(公告)号:US20100141753A1

    公开(公告)日:2010-06-10

    申请号:US12711157

    申请日:2010-02-23

    IPC分类号: H04N7/18

    摘要: Systems and methods for assessing and optimizing virtual microscope slide image quality are provided. In order to determine whether a virtual slide image has any out of focus areas and is therefore a candidate for manual inspection, the various focus points used to scan the virtual slide image are used to calculate a best fit surface for the virtual slide image. The distance of each focus point from the best fit surface is then calculated and the largest distance is compared to a predetermined value. If the largest distance from a focus point to the best fit surface is larger than the predetermined value, then the virtual slide image is designated as needing a manual inspection and possible re-scan.

    摘要翻译: 提供了评估和优化虚拟显微镜载玻片图像质量的系统和方法。 为了确定虚拟幻灯片图像是否具有任何偏离焦点区域,因此是用于手动检查的候选者,用于扫描虚拟幻灯片图像的各种对焦点用于计算虚拟幻灯片图像的最佳拟合曲面。 然后计算每个对焦点与最佳拟合表面的距离,并将最大距离与预定值进行比较。 如果从焦点到最佳配合曲面的最大距离大于预定值,则虚拟幻灯片图像被指定为需要手动检查和可能的重新扫描。

    Barrel cam loader arm assembly
    27.
    发明授权
    Barrel cam loader arm assembly 失效
    桶式凸轮装载机臂组件

    公开(公告)号:US06308502B1

    公开(公告)日:2001-10-30

    申请号:US09476011

    申请日:1999-12-29

    IPC分类号: B65B3530

    CPC分类号: B65B35/405

    摘要: A loader arm assembly for use in a packaging system, comprising an arm, a housing, and a load jam detector. The housing is operably connected to at least one motive mechanism, and is adapted for moving the arm to load product into a package. The arm has both a latched state and a released state with respect to the housing. The arm normally is in the latched state to load product into the package, and enters the released state to relieve pressure upon detecting the load jam condition. The arm includes a base plate and a loading head. The housing is formed with a guide passage that is adapted for receiving the base plate. The load jam detector preferably includes at least one detent adapted for holding the base plate with respect to the housing in the latched state. The detent preferably is formed by a tip of at least one plug extending through the housing to the guide passage. The tip is adapted for applying a holding force against the base plate. A first end of the base plate has at least one depression adapted for receiving the tip of the at least one plug in the latched state and for releasing the tip to slide on a surface of the base plate upon the application of a predetermined load pressure attributable to the load condition. The loader arm assembly is described and shown within a barrel cam loading mechanism that is incorporated into a continuous motion packaging mechanism, but may be used in other packaging systems such as a vertical cartoner or a sleever.

    摘要翻译: 一种用于包装系统的装载机臂组件,包括臂,壳体和负载阻塞检测器。 壳体可操作地连接到至少一个动力机构,并且适于移动臂以将产品装载到包装中。 臂相对于壳体具有锁定状态和释放状态。 手臂通常处于锁定状态,将产品装入包装中,并在检测到负载卡住状况时进入释放状态以减轻压力。 臂包括底板和装载头。 壳体形成有适于接收基板的引导通道。 所述负载卡纸检测器优选地包括至少一个制动器,其适于在所述锁定状态下相对于所述壳体保持所述基板。 止动件优选地由延伸穿过壳体的至少一个塞子的尖端形成为引导通道。 尖端适于对基板施加保持力。 基板的第一端具有至少一个凹部,该凹部适于接收处于闩锁状态的至少一个塞子的尖端,并且在施加预定的负载压力时释放尖端以在基板的表面上滑动 到负载条件。 装载机臂组件被描述并示出在筒状凸轮加载机构内,该机构结合到连续运动的包装机构中,但可以用于其它包装系统,例如垂直纸箱或舒适。

    Optimizing Virtual Slide Image Quality
    28.
    发明申请
    Optimizing Virtual Slide Image Quality 有权
    优化虚拟幻灯片图像质量

    公开(公告)号:US20120114204A1

    公开(公告)日:2012-05-10

    申请号:US13355245

    申请日:2012-01-20

    IPC分类号: G06K9/40

    摘要: Systems and methods for assessing and optimizing virtual microscope slide image quality are provided. In order to determine whether any of multiple virtual slide images has an out of focus area and is therefore a candidate for manual inspection or rescanning, various focus points used to scan each virtual slide image are used to calculate a best fit surface for each virtual slide image. The best fit surface is then used to determine whether any of the various focus points are outliers. If it is determined that a virtual slide image is associated with outlying focus points, it is identified as a candidate for manual inspection or rescanning.

    摘要翻译: 提供了评估和优化虚拟显微镜载玻片图像质量的系统和方法。 为了确定多个虚拟幻灯片图像中的任何一个是否具有失焦区域,因此是用于手动检查或重新扫描的候选者,用于扫描每个虚拟幻灯片图像的各种对焦点用于为每个虚拟幻灯片计算最佳拟合曲面 图片。 然后使用最佳拟合曲面来确定各个焦点中是否有异常值。 如果确定虚拟幻灯片图像与外围焦点相关联,则将其识别为手动检查或重新扫描的候选者。