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公开(公告)号:US20190299176A1
公开(公告)日:2019-10-03
申请号:US16303095
申请日:2017-06-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: David MARKEL , Pavel KORNILOVICH , Erik D TORNIAINEN , Alexander GOVYADINOV , Viktor SHKOLNIKOV , Diane R HAMMERSTAD , Ning GE
Abstract: Examples include microfluidic devices. Example microfluidic devices comprise a first microfluidic channel, a second microfluidic channel, and microfluidic output channel fluidly coupled to the first microfluidic channel and the second microfluidic channel via a fluid junction. The example device comprises a first fluid actuator disposed in the first microfluidic channel to actuate to thereby pump a first fluid into the microfluidic output channel, and the example device comprises a second fluid actuator disposed in the second microfluidic channel to actuate to pump a second fluid into the microfluidic output channel. The first fluid actuator and the second fluid actuator are to actuate to thereby pump a fluid mixture of the first fluid and the second fluid into the microfluidic output channel.
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公开(公告)号:US20190299169A1
公开(公告)日:2019-10-03
申请号:US16316896
申请日:2016-10-21
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Erik D. TORNIAINEN , Alexander N. GOVYADINOV , Pavel KORNILOVICH , David P. MARKEL , Richard W. SEAVER
Abstract: An immiscible droplet generation system may include a chip, a microfluidic channel integrated into the chip, an input to the microfluidic channel through which the microfluidic channel is to be filled with a first fluid that is to be moved through the microfluidic channel and a droplet generator. The droplet generator is integrated into the chip to generate a droplet of a second fluid, immiscible within the first fluid, and to inject the droplet into the first fluid in the microfluidic channel.
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公开(公告)号:US20190176111A1
公开(公告)日:2019-06-13
申请号:US16300182
申请日:2016-07-08
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: David P. MARKEL , Erik D. TORNIAINEN , Alexander GOVYADINOV , Pavel KORNILOVICH
Abstract: Examples include microfluidic devices. Example microfluidic devices comprise a first microfluidic channel, a second microfluidic channel, and microfluidic output channel fluidly coupled to the first microfluidic channel and the second microfluidic channel via a fluid junction. The example device comprises a fluid actuator disposed in the microfluidic output channel to actuate to thereby pump a first fluid and a second fluid into the microfluidic output channel.
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公开(公告)号:US20190143327A1
公开(公告)日:2019-05-16
申请号:US16300115
申请日:2016-07-15
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel KORNILOVICH , Alexander GOVYADINOV , David P. MARKEL , Erik D. TORNIAINEN
IPC: B01L3/00
Abstract: A microfluidic filtering system may include a first microfluidic channel, a first pump to move fluid along the first microfluidic channel in a first direction, a second microfluidic channel, a second pump to move fluid along the second microfluidic channel in a second direction opposite to the first direction and a filter channel extending between and interconnecting the first microfluidic channel and the second microfluidic channel.
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公开(公告)号:US20240181449A1
公开(公告)日:2024-06-06
申请号:US18550286
申请日:2021-04-06
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson DENISON , Pavel KORNILOVICH , Richard W. SEAVER , Anand Samuel JEBAKUMAR , Erik D. TORNIANEN , Alexander GOVYADINOV
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L2300/0864 , B01L2300/161 , B01L2400/0406
Abstract: A microfluidic device includes a first channel, second channels, and a transition channel splitting the first channel into the second channels. The transition has a first end fluidically connected to the first channel and a second end fluidically connected to the second channels. The transition channel expands in width from a width of the first channel at the first end to no less than a sum of widths of the second channels at the second end so as to promote fluid flow from the first channel to the second channels.
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公开(公告)号:US20240165617A1
公开(公告)日:2024-05-23
申请号:US18550353
申请日:2021-04-06
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Erik D. TORNIANEN , Carson DENISON , Richard W. SEAVER , Anand Samuel JEBAKUMAR , Pavel KORNILOVICH , Alexander GOVYADINOV
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L2300/0877 , B01L2400/0406
Abstract: A microfluidic device includes a first channel having a first width and a second channel having a second width greater than the first width. The microfluidic device includes a transition channel having a first end fluidically connected to the first channel and a second end fluidically connected to the second channel. The transition channel expands in width from the first width to the second width so as to promote fluid flow from the first channel to the second channel.
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公开(公告)号:US20230415151A1
公开(公告)日:2023-12-28
申请号:US17848864
申请日:2022-06-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Peiyun Wang , Pavel KORNILOVICH , Alexander GOVYADINOV , Noorashekin Binte JAMIL , Sarita JAIRAM , Jinghua ZHAO
CPC classification number: B01L3/502715 , G01N11/00 , B01L2200/0647 , B01L2400/0406
Abstract: An example self-priming microfluidic structure can include a microfluidic channel including a floor and a ceiling. A channel height is defined as a distance between the floor and the ceiling. A channel height step can be in the floor, or ceiling, or both. The channel height downstream of the channel height step can be greater than the channel height upstream of the channel height step. An interior pillar can be positioned in the microfluidic channel extending from the floor to the ceiling. The interior pillar can include a widening portion at an upstream end of the interior pillar and a tapering portion at a downstream end of the interior pillar. The interior pillar can overlap the channel height step so that the interior pillar is partially upstream of the channel height step and partially downstream of the channel height step.
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公开(公告)号:US20230035535A1
公开(公告)日:2023-02-02
申请号:US17384376
申请日:2021-07-23
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Pavel KORNILOVICH , Alexander GOVYADINOV , Anand Samuel JEBAKUMAR
IPC: B01L3/00
Abstract: An example microfluidic device comprises a plurality of fluidic channels and a fluidic multiplexor. The fluidic multiplexor includes a plurality of fluidic micro-valves fluidically coupled to the plurality of fluidic channels, and a plurality of control lines that cross the plurality of fluidic channels proximal to the plurality of fluidic micro-valves.
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公开(公告)号:US20210322992A1
公开(公告)日:2021-10-21
申请号:US17268975
申请日:2019-05-06
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Pavel KORNILOVICH , Alexander GOVYADINOV
Abstract: A rapid thermal cycling device can include a microfluidic reaction chamber, a dry reagent, and a heating element. The microfluidic reaction chamber can be defined between a substrate and a cover having an average space therebetween from 4 μm to 150 μm. The dry reagent can be positioned within the microfluidic reaction chamber. The heating element can be thermally coupled to the microfluidic reaction chamber to heat a fluid when introduced therein.
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公开(公告)号:US20210322991A1
公开(公告)日:2021-10-21
申请号:US17268971
申请日:2018-12-13
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Diane HAMMERSTAD , Alexander GOVYADINOV , Brian J. KEEFE , Erik D. TORNIAINEN , Tyler COCHELL , Pavel KORNILOVICH
Abstract: A rapid thermal cycling device can include a static microfluidic reaction chamber that can be defined between a layered substrate and a cover that can have an average space therebetween from 4 μm to 150 μm. The layered substrate can include a heating element thermally coupled to the static microfluidic reaction chamber to heat a fluid when present therein. The layered substrate, the cover, or both can include a heat diffusing material thermally coupled to the static microfluidic reaction chamber to diffuse heat out from the fluid while remaining in the static microfluidic reaction chamber.
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