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公开(公告)号：US20250033042A1
公开(公告)日：2025-01-30
申请号：US18715100
申请日：2021-12-10
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor SHKOLNIKOV , Angela BAKKOM , Christopher Hans BAKKER , Matthew David SMITH
Abstract: An example microfluidic device comprises a microfluidic channel fluidically coupled to a reservoir containing a fluid, a first sensor disposed within the microfluidic channel, a second sensor disposed within the microfluidic channel, a first dielectrophoretic (DEP) actuator disposed within the microfluidic channel between the first sensor and the second sensor, and a fluid ejection device fluidically coupled to the microfluidic channel.
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公开(公告)号：US20240253296A1
公开(公告)日：2024-08-01
申请号：US18559987
申请日：2021-05-11
Inventor： Wei Long NG , Xi HUANG , Viktor SHKOLNIKOV , Roberto A. PUGLIESE , Mackenzie JOHNSON , Wai Yee YEONG
IPC: B29C64/112 , B29C64/209 , B29C64/245 , B29C64/255 , B29K101/00 , B33Y10/00 , B33Y30/00 , B33Y70/10 , C12N5/00
CPC classification number: B29C64/112 , B29C64/209 , B29C64/245 , B29C64/255 , B33Y10/00 , B33Y30/00 , C12N5/0062 , B29K2101/00 , B33Y70/10 , C12N2513/00 , C12N2533/30
Abstract: The present disclosure is drawn to bio-ink printer components, methods of printing bio-inks, and multi-fluid live cell printing systems. In one example, a bio-ink printer component can include a bio-ink and a bio-ink ejector fluidly connected or connectable to the bio-ink. The bio-ink can include a buffer solution that is suitable for live cells, and a polymer that includes polyvinylpyrrolidone, polyvinyl alcohol, polyvinyl sulfate, polyethylene glycol, polyester, poly(dimethylsiloxane), cellulose, polysaccharide, or a combination thereof. The bio-ink ejector can include an ejection nozzle and a thermal resistor positioned to heat the bio-ink to form a vapor bubble to eject a droplet of bio-ink from the ejection nozzle.
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公开(公告)号：US20230001692A1
公开(公告)日：2023-01-05
申请号：US17782875
申请日：2020-02-14
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor SHKOLNIKOV , Alexander GOVYADINOV
IPC: B41J2/14
Abstract: In example implementations, an apparatus is provided. The apparatus includes a channel, an opening in the channel, and a heating element aligned with the opening on opposite sides of the channel. The channel contains a droplet of a first liquid containing a particle, wherein the droplet is carried within a second liquid in the channel. The heating element is to heat the first liquid to generate a vapor in the first liquid to eject the droplet of the first liquid through the opening.
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公开(公告)号：US20220072535A1
公开(公告)日：2022-03-10
申请号：US17415839
申请日：2019-04-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor SHKOLNIKOV , Alexander GOVYADINOV
IPC: B01L3/00
Abstract: The present disclosure relates to a microfluidic device including a microfluidic substrate and dry reagent-containing polymer particles. The microfluidic substrate includes a microfluidic-retaining region within the microfluidic substrate that is fluidly coupled to multiple microfluidic channels. The dry reagent-containing polymer particles include reagent and a degradable polymer. The reagent is releasable from the degradable polymer when exposed to release fluid. The dry reagent-containing particles are retained within the microfluidic substrate at the microfluidic-retaining region in position to release reagent into the egress microfluidic channel upon flow of release fluid from the ingress microfluidic channel through the microfluidic-retaining region.
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公开(公告)号：US20190049386A1
公开(公告)日：2019-02-14
申请号：US16076344
申请日：2017-01-31
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Ning GE , Viktor SHKOLNIKOV , Anita ROGACS , Steven J. SIMSKE
IPC: G01N21/65
Abstract: A surface enhanced luminescence (SEL) sensor may include a substrate and nano fingers projecting from the substrate. The nano fingers may include a nano finger extending along an axis. The nano finger may include a plasmonically active cap and a pillar supporting the plasmonically active cap. The pillar may have an asymmetric material composition with respect to the axis.
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Patent Agency Ranking
公开(公告)号：US20230173497A1
公开(公告)日：2023-06-08
申请号：US17911838
申请日：2020-04-29
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor SHKOLNIKOV , Alexander GOVYADINOV
CPC classification number: B01L7/52 , B01L3/502715 , C12Q1/686 , B01L3/502761 , B01L2300/0896 , B01L2400/043 , B01L2400/0487
Abstract: Examples relate to techniques for performing a nucleic acid amplification reaction. The method includes generating a nucleic acid solution comprising a plurality of nucleic acid molecules, and combining the nucleic acid solution with a plurality of chamber particles. Each chamber particle includes a chamber for receiving the nucleic acid solution, wherein the chamber receives, at most, one of the plurality of nucleic acid molecules. Each chamber particle also includes reagents for causing a polymerase chain reaction within the chamber. The method further includes inducing nucleic acid amplification to generate an amplified nucleic acid, and performing a detection process to detect the presence of the amplified nucleic acid within the chamber.
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公开(公告)号：US20230132556A1
公开(公告)日：2023-05-04
申请号：US17911559
申请日：2020-04-07
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor SHKOLNIKOV , Daixi XIN
Abstract: A cell transfection apparatus may include a microfluidic chip. The microfluidic chip may include a fluid input port, a cell sorter to sort target cells from non-target cells in fluid received through the input port, a cell transfection region comprising a single cell electroporation region to receive the target cells sorted from the nontarget cells and a fluid ejector to dispense a transfected target cell received from the cell transfection region.
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公开(公告)号：US20210205809A1
公开(公告)日：2021-07-08
申请号：US16077362
申请日：2017-07-17
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor SHKOLNIKOV , Kenneth WARD
Abstract: A microfluidic device may, in an example, include at least one microfluidic channel, a dielectrophoresis separator to separate a plurality of cells passing within the at least one microfluidic channel, and a thermal resistor to eject at least one cell from the microfluidic device. A cassette may, in an example, include a die coupled to a substrate of the cassette, the die including at least one microfluidic channel, a dielectrophoresis separator along the microfluidic channel to separate a plurality of cells passing within the microfluidic channel, and an ejection device to eject at least one of the plurality of cells into an assay well.
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公开(公告)号：US20190299176A1
公开(公告)日：2019-10-03
申请号：US16303095
申请日：2017-06-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： David MARKEL , Pavel KORNILOVICH , Erik D TORNIAINEN , Alexander GOVYADINOV , Viktor SHKOLNIKOV , Diane R HAMMERSTAD , Ning GE
Abstract: Examples include microfluidic devices. Example microfluidic devices comprise a first microfluidic channel, a second microfluidic channel, and microfluidic output channel fluidly coupled to the first microfluidic channel and the second microfluidic channel via a fluid junction. The example device comprises a first fluid actuator disposed in the first microfluidic channel to actuate to thereby pump a first fluid into the microfluidic output channel, and the example device comprises a second fluid actuator disposed in the second microfluidic channel to actuate to pump a second fluid into the microfluidic output channel. The first fluid actuator and the second fluid actuator are to actuate to thereby pump a fluid mixture of the first fluid and the second fluid into the microfluidic output channel.
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公开(公告)号：US20190056299A1
公开(公告)日：2019-02-21
申请号：US15770479
申请日：2016-02-29
Applicant: Hewlett-Packard Development Company , L.P.
Inventor： Viktor SHKOLNIKOV , Anita ROGACS
Abstract: An enzymatic sample purifier comprises a reaction chamber containing an enzyme, a product chamber and a separator. The reaction chamber has a port to receive a sample comprising a protein degradation product. The separator retains polypeptides resulting from reaction of the protein degradation product with the enzyme in the reaction chamber and facilitates transport of purified remaining portions of the sample comprising a target analyte to the product chamber.
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