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21.发明授权Dibenzoylmethane sunscreen compositions photostabilized with amphiphilic block copolymers 失效二苯甲酰甲烷防晒组合物用两亲嵌段共聚物光稳定化公开(公告)号：US07153494B2
公开(公告)日：2006-12-26
申请号：US10688937
申请日：2003-10-21
CPC分类号： A61K8/35 , A61K8/90 , A61K2800/52 , A61Q17/04
摘要： Topically applicable photostable sunscreen/photoprotective compositions contain at least one dibenzoylmethane UV-sunscreen and an effective photostabilizing amount therefor of at least one amphiphilic block copolymer which comprises at least one nonionic hydrophilic polymer block and at least one hydrophobic polymer block, formulated into a topically applicable, cosmetically acceptable medium therefor.
摘要翻译： 局部适用的光稳定防晒剂/光保护组合物含有至少一种二苯甲酰甲烷紫外线防晒剂和至少一种两亲性嵌段共聚物的有效光稳定剂，其包含至少一种非离子亲水性聚合物嵌段和至少一种疏水性聚合物嵌段，其配制成局部适用的 ，化妆品可接受的介质。
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22.发明申请公开(公告)号：US20060263438A1
公开(公告)日：2006-11-23
申请号：US11434828
申请日：2006-05-17
CPC分类号： A61Q19/00 , A61K8/025 , A61K8/31 , A61K8/37 , A61K8/44 , A61K8/8152 , A61K8/88 , A61K9/0014 , A61K9/1617 , A61K9/5123 , A61K2800/412 , A61K2800/614 , A61Q19/008
摘要： The present invention relates to calibrated and spherical oily particles comprising at least one oily phase structured with at least one gelling polymer, characterized in that they have a mean size of less than or equal to 15 μm, in that the said structured oily phase has a melting point of greater than or equal to 40° C. and in that their circularity index is between 0.9 and 1.
摘要翻译： 本发明涉及校准的和球形的油性颗粒，其包含至少一个由至少一种胶凝聚合物构成的油相，其特征在于它们具有小于或等于15μm的平均尺寸，因为所述结构化的油相具有 熔点大于或等于40℃，其圆形度指数在0.9和1之间。
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23.发明授权Nanoemulsion based on alkoxylated alkenyl succinates or alkoxylated alkenyl succinates of glucose and its uses in the cosmetics, dermatological, opthalmological and/or pharmaceutical fields 失效基于葡萄糖的烷氧基化烯基琥珀酸酯或烷氧基化烯基琥珀酸盐的纳米乳液及其在化妆品，皮肤病学，眼科学和/或药物领域中的用途公开(公告)号：US06461625B1
公开(公告)日：2002-10-08
申请号：US09489839
申请日：2000-01-24
IPC分类号： A61K600
CPC分类号： C07D401/06 , Y10S514/844 , Y10S514/873 , Y10S514/937 , Y10S514/938 , Y10S514/939
摘要： A nanoemulsion, the oil globules of which have an average size of less than 100 nm, comprising a surfactant chosen from the alkoxylated alkenyl succinates, the alkoxylated alkenyl succinates of glucose and the alkoxylated alkenyl succinates of methylglucose, and at least one oil having a molecular weight of greater than 400, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The emulsion obtained is transparent and stable on storage. It can comprise large amounts of oil while retaining good transparency and while having good cosmetic properties. It can constitute a composition for topical use, a pharmaceutical composition or an ophthalmological composition.
摘要翻译： 纳米乳剂，其平均粒径小于100nm的纳米乳液，包含选自烷氧基化烯基琥珀酸盐，葡萄糖的烷氧基化烯基琥珀酸盐和甲基葡萄糖的烷氧基化烯基琥珀酸盐的表面活性剂，以及至少一种具有分子 重量大于400，油相量与表面活性剂的重量比为2至10.所获得的乳液在储存时是透明和稳定的。 它可以包含大量的油，同时保持良好的透明度并且同时具有良好的化妆品性质。 它可以构成用于局部使用的组合物，药物组合物或眼科学组合物。
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24.发明授权Nanoemulsion based on ethoxylated fatty ethers or on ethoxylated fatty esters and its uses in the cosmetics, dermatological and/or ophthalmological fields 有权基于乙氧基化脂肪醚或乙氧基化脂肪酯的纳米乳液及其在化妆品，皮肤病学和/或眼科领域中的应用公开(公告)号：US06375960B1
公开(公告)日：2002-04-23
申请号：US09474074
申请日：1999-12-29
IPC分类号： A61K600
CPC分类号： A61Q19/00 , A61K8/06 , A61K9/0048 , A61K9/1075 , A61K2800/21 , A61K2800/262 , A61K2800/413 , A61Q1/14 , A61Q5/00 , A61Q19/007 , B01F17/0021 , B82Y5/00 , Y10S514/844 , Y10S514/845 , Y10S514/937 , Y10S514/938
摘要： The present invention provides a nanoemulsion, that includes: an oily phase dispersed in an aqueous phase; and at least one surfactant that is solid at a temperature of less than or equal to 45° C. and which is selected from the group including ethoxylated fatty ethers and ethoxylated fatty esters, and mixtures thereof; wherein the oily phase includes oil globules having a number-average size of less than 100 nm; wherein the oily phase includes at least one oil having a molecular weight of greater than 400; and wherein a weight ratio of the oily phase to the surfactant ranges from 2 to 10. The invention also provides a process for making the nanoemulsion, and methods for its use. The emulsion is ideally transparent and stable on storage. It can ideally contain large amounts of oil while retaining good transparency and good cosmetic properties. The nanoemulsion is particularly useful in compositions, including topical, pharmaceutical, cosmetic, opthalmic, ophthalmologic. The composition is also particularly useful in applications to the skin, hair, scalp, mucous membranes, and eyes.
摘要翻译： 本发明提供一种纳米乳液，其包括：分散在水相中的油相; 和至少一种在小于或等于45℃的温度下为固体的表面活性剂，并且其选自乙氧基化脂肪醚和乙氧基化脂肪酯，以及它们的混合物; 其中油相包括数均分子量小于100nm的油球;其中油相包含至少一种分子量大于400的油; 并且其中油相与表面活性剂的重量比为2至10.本发明还提供了制备纳米乳液的方法及其使用方法。 乳液在储存时理想的透明和稳定。 它理想地含有大量的油，同时保持良好的透明度和良好的化妆品性能。 纳米乳液在组合物中特别有用，包括局部，药物，化妆品，眼科，眼科学。 该组合物在对皮肤，毛发，头皮，粘膜和眼睛的应用中也特别有用。
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公开(公告)号：US6022559A
公开(公告)日：2000-02-08
申请号：US978377
申请日：1997-11-25
IPC分类号： A61K9/127 , A61K8/00 , A61K8/14 , A61K8/37 , A61K8/39 , A61K8/72 , A61K8/73 , A61K8/81 , A61K8/85 , A61K8/87 , A61K8/98 , A61K47/30 , A61Q5/00 , A61Q19/08 , A61K6/00 , A61K7/06
摘要： A dispersion, in an aqueous medium, of dehydration-resistant vesicles containing a lipid phase and an encapsulated aqueous phase. The dispersion additionally contains, either in the aqueous medium or in the encapsulated aqueous phase or in both, at least one polymer, in the form of particles, which has a glass transition temperature Tg, in the presence or absence of a plasticizing agent, of lower than 70.degree. C. at 0% relative humidity. The dispersion can be used in the cosmetic or pharmaceutical fields for topical application for the care and/or makeup of the skin and for care of the scalp and/or hair.
摘要翻译： 在含水介质中的含有脂质相和封装水相的耐脱水小泡的分散体。 该分散体在含水介质或包封的水相中或在两者中还含有颗粒形式的至少一种聚合物，其在存在或不存在增塑剂的情况下具有玻璃化转变温度Tg， 在0％相对湿度下低于70℃。 分散体可用于化妆品或药物领域，用于局部应用于皮肤护理和/或化妆以及护理头皮和/或头发。
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公开(公告)号：US5679691A
公开(公告)日：1997-10-21
申请号：US597101
申请日：1996-02-06
IPC分类号： A61K8/30 , A61K8/00 , A61K8/06 , A61K8/11 , A61K8/14 , A61K8/19 , A61K8/34 , A61K8/37 , A61K8/39 , A61K8/40 , A61K8/44 , A61K8/49 , A61K8/60 , A61K8/64 , A61K8/66 , A61K8/67 , A61K8/72 , A61K8/73 , A61K8/86 , A61K8/92 , A61K8/97 , A61K9/127 , A61K31/135 , A61K31/15 , A61K31/42 , A61K31/44 , A61K31/445 , A61P17/00 , A61P17/10 , A61P43/00 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61K7/40 , A61K7/42
CPC分类号： B82Y5/00 , A61K31/135 , A61K31/15 , A61K31/42 , A61K31/445 , A61K8/14 , A61K8/4926 , A61K9/1272 , A61Q17/04 , A61Q19/00 , A61Q19/08 , Y10S977/778 , Y10S977/78 , Y10S977/926
摘要： The invention relates to the use of a spin trap employed as an electron paramagnetic resonance measurement probe, in a cosmetic or dermatological composition for the light-protective, anti-ageing and/or anti-acne treatment of the skin. In particular, this spin trap is encapsulated in lipid vesicles which are capable of diffusing into the deep layers of the skin.
摘要翻译： 本发明涉及在化妆品或皮肤病学组合物中用作电子顺磁共振测量探针的自旋阱，其用于皮肤的光保护性，抗老化和/或抗痤疮治疗。 特别地，该自旋捕获器被包封在能够扩散到皮肤深层的脂质囊泡中。
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27.发明授权
公开(公告)号：US5601833A
公开(公告)日：1997-02-11
申请号：US366741
申请日：1994-12-30
IPC分类号： A61K8/30 , A61K8/00 , A61K8/14 , A61K8/25 , A61K8/34 , A61K8/37 , A61K8/39 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/64 , A61K8/66 , A61K8/67 , A61K8/68 , A61K8/72 , A61K8/73 , A61K8/88 , A61K8/92 , A61K8/96 , A61K8/97 , A61K8/98 , A61Q17/00 , A61Q19/00 , A61K9/127
CPC分类号： A61K8/4926 , A61K8/14 , A61K8/42 , A61K8/49 , A61K8/673 , A61K8/678 , A61Q17/00 , A61Q19/00 , A61K2800/59
摘要： Compositions comprising a first dispersion of lipid vesicles which are capable of penetrating into the deep layers of the skin and which contain at least one active agent chosen from anti-oxygenated-free-radical agents, proteins, sugars, enzymes, vitamins, nucleotides and sequences thereof, trace elements, coenzymes, unsaturated fatty acid-rich phospholipids, silicon derivatives and plant extracts, for treating these deep layers, and a second dispersion of lipid vesicles which are capable of penetrating into the surface layers of the skin and which contain at least one active agent chosen from screening agents, anti-oxygenated-free-radical agents, sugars, amino acids, vitamins, ceramides, unsaponifiable products derived from plant oils, and components of sweat, for treating these surface layers, are effective protecting, nourishing and/or firming the skin.
摘要翻译： 包含脂质囊泡的第一分散体的组合物，其能够渗入皮肤的深层并且含有至少一种选自抗氧合自由基剂，蛋白质，糖，酶，维生素，核苷酸和序列的活性剂 微量元素，辅酶，富含不饱和脂肪酸的磷脂，硅衍生物和植物提取物，用于处理这些深层，以及脂质囊泡的第二分散体，其能够渗透到皮肤的表层中并且至少含有 选自筛选剂，抗氧化自由基剂，糖，氨基酸，维生素，神经酰胺，来源于植物油的不皂化物和用于处理这些表面层的汗液成分的一种活性剂是有效的保护，滋养和 /或使皮肤紧致。
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公开(公告)号：US10555887B2
公开(公告)日：2020-02-11
申请号：US13996179
申请日：2011-12-20
摘要： The subject matter of the present invention is a sterile liquid composition dedicated to administration into or through the skin and/or the lips, wherein said composition comprises, in a physiologically acceptable medium, at least one photo-crosslinkable compound, wherein said compound comprises at least one activated photo-dimerizable group having at least one activated double bond and selected from photo-dimerizable groups carrying a stilbazolium function of formula (Ia) or (Ib) and wherein the photo-dimerizable groups carry a styrylazolium function of formula (II), the photo-dimerizable group(s) being carried by a partially or totally hydrolysed poly(vinyl acetate) polymer, a polysaccharide or a polyvinyl alcohol.
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公开(公告)号：US10449126B2
公开(公告)日：2019-10-22
申请号：US12637803
申请日：2009-12-15
摘要： The present invention relates to a composition in the form of an emulsion of the oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and which are dispersed in an aqueous phase, wherein it has a pH ranging from 3 to 5.5 and in that it contains at least one lipophilic surface-active agent with an HLB ranging from 2 to 5, at least one hydrophilic surface-active agent with an HLB ranging from 8 to 12 and at least one amphiphilic compound of ionic nature at a pH ranging from 3 to 5.5.
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30.发明授权Nanoemulsion based on sugar fatty esters or on sugar fatty ethers and its uses in the cosmetics, dermatological and/or ophthalmological fields 有权基于糖脂肪酯或糖脂肪醚的纳米乳液及其在化妆品，皮肤病学和/或眼科领域中的应用公开(公告)号：US08834903B2
公开(公告)日：2014-09-16
申请号：US10724826
申请日：2003-12-02
CPC分类号： A61Q19/007 , A61K8/06 , A61K8/062 , A61K8/60 , A61K8/602 , A61K2800/21 , A61K2800/413 , A61Q1/14 , A61Q5/00 , A61Q19/00 , B82Y5/00 , Y10S514/938
摘要： A nanoemulsion, the oily globules of which have a number-average size of less than 100 nm, comprising a surfactant which is solid at a temperature of less than or equal to 45° C., which surfactant is chosen from esters of a fatty acid and of a sugar and ethers of a fatty alcohol and of a sugar, and at least one oil having a molecular weight of greater than 400, the ratio by weight of the amount of oily phase to the amount of surfactant ranging from 2 to 10. The nanoemulsion may be used for cosmetics and dermatological applications, in particular for moisturizing the skin and/or mucous membranes, as well as for treating the hair, and in the ophthalmological field, as an eye lotion for treating the eyes.
摘要翻译： 纳米乳液的数均粒径小于100nm的纳米乳液包含在小于或等于45℃的温度下为固体的表面活性剂，该表面活性剂选自脂肪酸的酯 以及脂肪醇和糖的糖和醚，以及至少一种分子量大于400的油，油相量与表面活性剂的重量比为2至10。 纳米乳液可以用于化妆品和皮肤病学应用，特别是用于保湿皮肤和/或粘膜，以及用于治疗头发和在眼科领域中，作为用于治疗眼睛的眼液。
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