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33 条记录 (耗时 0.025 秒)

    Peptides, compositions and uses thereof
    24.
    发明授权
    Peptides, compositions and uses thereof 失效
    肽，组合物及其用途

    公开(公告)号：US08614187B2

    公开(公告)日：2013-12-24

    申请号：US13530550

    申请日：2012-06-22

    申请人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    发明人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    IPC分类号： A61K38/08

    CPC分类号： C07K7/18 ,  C07K14/47

    摘要： Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

    摘要翻译： 描述的是最大蛋白质的N末端六肽片段，QUB 698.8，其在平滑肌上表现出有力的组织选择性作用。 它表现出对小肠平滑肌的动脉平滑肌的高度选择性，导致动脉平滑肌的强力松弛，同时引起回肠平滑肌的较不有效的收缩。 它可用于治疗心血管系统疾病和促进血管生成。

    PEPTIDES, COMPOSITIONS AND USES THEREOF
    25.
    发明申请
    PEPTIDES, COMPOSITIONS AND USES THEREOF 失效
    肽，组合物及其用途

    公开(公告)号：US20120295851A1

    公开(公告)日：2012-11-22

    申请号：US13530550

    申请日：2012-06-22

    申请人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    发明人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    IPC分类号： A61K38/08

    CPC分类号： C07K7/18 ,  C07K14/47

    摘要： Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

    摘要翻译： 描述的是最大蛋白质的N末端六肽片段，QUB 698.8，其在平滑肌上表现出有力的组织选择性作用。 它表现出对小肠平滑肌的动脉平滑肌的高度选择性，导致动脉平滑肌的强力松弛，同时引起回肠平滑肌的较不有效的收缩。 它可用于治疗心血管系统疾病和促进血管生成。

    Peptides, compositions and uses thereof
    26.
    发明授权
    Peptides, compositions and uses thereof 失效
    肽，组合物及其用途

    公开(公告)号：US08217011B2

    公开(公告)日：2012-07-10

    申请号：US12449950

    申请日：2008-03-07

    申请人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    发明人： Christopher Shaw ,  Tianbao Chen ,  Martin O'Rourke ,  Brian Walker ,  David Hirst

    IPC分类号： A61K38/08 ,  A61L15/16 ,  C07K7/06

    CPC分类号： C07K7/18 ,  C07K14/47

    摘要： Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.

    摘要翻译： 描述的是最大蛋白质的N末端六肽片段，QUB 698.8，其在平滑肌上表现出有力的组织选择性作用。 它表现出对小肠平滑肌的动脉平滑肌的高度选择性，导致动脉平滑肌的强力松弛，同时引起回肠平滑肌的较不有效的收缩。 它可用于治疗心血管系统疾病和促进血管生成。

    Charging control system for group communication sessions
    28.
    发明授权
    Charging control system for group communication sessions 失效
    组通信会话的充电控制系统

    公开(公告)号：US07693510B2

    公开(公告)日：2010-04-06

    申请号：US11563105

    申请日：2006-11-24

    申请人： Christopher Shaw

    发明人： Christopher Shaw

    IPC分类号： H04M11/00 ,  H04M15/00

    CPC分类号： H04L12/14

    摘要： The invention relates to a system for controlling communication between user terminals using a telecommunications network. One embodiment includes an interface between a real-time charging control system for controlling usage of network resources during such usage and a group communications control node which is capable of controlling group communications sessions. Improved real-time charging control mechanisms can be implemented to account for usage of group communications services, for example where charging for an entire group communications session may be applied to a selected single party. Charging for a group communications session may be conducted with the flexibility of being able to charge according to the number of participants without having to transmit separate charging control signals from each participant's leg of the session to the real-time charging control system, thus reducing the signaling load in the network.

    摘要翻译： 本发明涉及一种用于控制使用电信网络的用户终端之间的通信的系统。 一个实施例包括在这种使用期间控制网络资源的使用的实时计费控制系统和能够控制组通信会话的组通信控制节点之间的接口。 可以实现改进的实时计费控制机制以解决组通信服务的使用，例如，可以将整个组通信会话的计费应用于所选择的单个方。 可以灵活地进行群组通信会话的充电，其能够根据参与者的数量进行收费，而不必将单独的计费控制信号从会话的每个参与者的腿部发送到实时计费控制系统，从而减少 网络中的信令负载。

    Call processing in mobile telecommunications networks
    29.
    发明授权
    Call processing in mobile telecommunications networks 有权
    移动电信网络中的呼叫处理

    公开(公告)号：US07653389B2

    公开(公告)日：2010-01-26

    申请号：US10497552

    申请日：2002-12-20

    申请人： Michael David Eales ,  Michael Andrew Williams ,  Dominic Desmond Phelim O'Neill ,  Christopher Shaw

    发明人： Michael David Eales ,  Michael Andrew Williams ,  Dominic Desmond Phelim O'Neill ,  Christopher Shaw

    IPC分类号： H04W4/00

    CPC分类号： H04W88/184 ,  H04Q3/0029 ,  H04W76/11 ,  H04W76/18 ,  H04W88/18 ,  H04W92/24

    摘要： A mobile telephone network has a function (30) which interacts with the platform (40) or platforms processing a call, event or session to: a) determine the services and/or call handling operations to be applied to the call, event or session; and b) determine if the platform(s) (40) are capable of carrying out the services and/or call handling operations required by the call, event or session. The function may then arrange for the platform (40) to be provided with appropriate data or for the call, event or session to be transferred to another platform. Moreover, a call may have part of its data converted into a standard protocol, and the data in that standard protocol then be used to guarantee a trigger for processing the call at a transfer device.

    摘要翻译： 移动电话网络具有与平台（40）或处理呼叫，事件或会话的平台交互的功能（30），以便：a）确定要应用于呼叫，事件或会话的服务和/或呼叫处理操作 ; 以及b）确定平台（40）是否能够执行呼叫，事件或会话所需的服务和/或呼叫处理操作。 然后，该功能可以安排将平台（40）提供适当的数据，或者将呼叫，事件或会话传送到另一个平台。 此外，呼叫可以将其数据的一部分转换成标准协议，然后使用该标准协议中的数据来保证在传送设备处理呼叫的触发。

    CHARGING CONTROL SYSTEM FOR GROUP COMMUNICATION SESSIONS
    30.
    发明申请
    CHARGING CONTROL SYSTEM FOR GROUP COMMUNICATION SESSIONS 失效
    集团通讯会议充电控制系统

    公开(公告)号：US20070160183A1

    公开(公告)日：2007-07-12

    申请号：US11563105

    申请日：2006-11-24

    申请人： Christopher Shaw

    发明人： Christopher Shaw

    IPC分类号： H04M15/00

    CPC分类号： H04L12/14

    摘要： The invention relates to a system for controlling communication between user terminals using a telecommunications network. One embodiment includes an interface between a real-time charging control system for controlling usage of network resources during such usage and a group communications control node which is capable of controlling group communications sessions. Improved real-time charging control mechanisms can be implemented to account for usage of group communications services, for example where charging for an entire group communications session may be applied to a selected single party. Charging for a group communications session may be conducted with the flexibility of being able to charge according to the number of participants without having to transmit separate charging control signals from each participant's leg of the session to the real-time charging control system, thus reducing the signaling load in the network.

    摘要翻译： 本发明涉及一种用于控制使用电信网络的用户终端之间的通信的系统。 一个实施例包括在这种使用期间控制网络资源的使用的实时计费控制系统和能够控制组通信会话的组通信控制节点之间的接口。 可以实现改进的实时计费控制机制以解决组通信服务的使用，例如，可以将整个组通信会话的计费应用于所选择的单个方。 可以灵活地进行群组通信会话的充电，其能够根据参与者的数量进行收费，而不必将单独的计费控制信号从会话的每个参与者的腿部发送到实时计费控制系统，从而减少 网络中的信令负载。