摘要:
This document provides materials and methods related to tissue scaffolds for use in replacing or augmenting various tissues in the body. For example, flexible tissue scaffolds with controlled pore geometry and methods of enhancing solute transport using rhythmic compression (e.g., 1.0 Hz) of tissue scaffolds are provided
摘要:
A system and method is provided for estimating the local noise of CT images and denoising the images using a modified non-local means (NLM) algorithm that is adaptive to local variations of noise levels. A strategy for efficiently estimating the local noise of CT images is also described.
摘要:
A method for reconstructing a time series of images from data acquired with a medical imaging system is provided. Data is acquired with the medical imaging system, and a set of image blocks that defines the location and size of each of a plurality of image blocks in the image domain is then selected. The acquired data and selected image block set are then used to jointly estimate a plurality of images that form a time series of images while promoting locally-low rank structure in the images.
摘要:
Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. A first graphical image may be generated from a first set of data elements from the k-space data. Similarly, a second graphical image may be generated from a second set of data elements from the k-space data. An offset in pixels may be determined by which to translate the second graphical image from the first graphical image to compensate for the motion. The k-space data may be modified at a sub-pixel offset relative to the determined offset. A motion-compensated graphical image of the subject may be generated from the modified k-space data. Doing so reduces the search space evaluated to sharpen images generated from the k-space data.
摘要:
Projection data acquired with an x-ray CT system is filtered using a bilateral filter to reduce image noise and enable the acquisition at lower x-ray dose without the loss of image diagnostic quality. The bilateral filtering is performed before image reconstruction by producing a noise equivalent data set from the acquired projection data and then converting the bilateral filtered values back to a projection data set suitable for image reconstruction.
摘要:
An improved method for processing image voxel data representative of 3-dimensional images of a colon to remove the effects of tagged stool. The method uses parabolic curve intensity-gradient models at a transition between two material types as a function of the fraction of the two materials for each of a plurality of two-material type classes, including a gas-tissue transition model, a gas-stool transition model and a stool-tissue transition model. The voxels are classified into one of a plurality of substance classes including tagged stool, gas, tissue and unknown classes. The unknown class voxels are processed to classify the unknown class voxels into one of the two-material type classes. The two-material type class voxels are processed to determine the fractions of materials in each voxel. The intensity of the two-material type class voxels is then adjusted as a function of the fraction of the materials in the voxels.
摘要:
Magnetic resonance images reconstructed from a radial/projection acquisition are corrected for motion corruption caused by in-plane translational and in-plane rotational motion of an imaged subject using only the projection data itself. The method is based on the consistency properties of the 0th, 1st, and 2nd order moments of the spatial domain projections. In-plane translational motion is corrected by shifting/aligning the spatial projections according to the center of mass of each projection, which is calculated using the 0th and 1st moments. In-plane rotational motion is accounted for by determining the rotational motion time record using the 2nd moment information. The determination of the rotational motion time record using the 2nd moments is made possible by acquiring the successive MR projections at a view angle spacing that is substantially 45° and thus achieves sufficient linear independence. The translation-corrected spatial projections are reconstructed using the actual projection view angles, which are sum of the intended projection view angles plus the detected in-plane rotational motion time record. The calculation may also be performed in real-time during data acquisition in order to reacquire projections found to be too inconsistent due to through plane motion or other changes that are not in-plane rigid body motions or to acquire projections determined to be missing from the data set due to rotational motion.
摘要:
A method for processing CT colonography input image voxel data representative of 3-dimensional images of a colon having gas and stool tagged with stool tagging agent, to remove the stool from the images. The input image voxel data is generated by an imaging instrument having a characteristic point spread function representative of instrument blurring. The point spread function of the instrument can be empirically determined, and the image data processed as a function of the point spread function to accurately identify and remove the tagged stool. In one embodiment of the invention, portions of the image data representative of the tagged stool and colon tissue are dilated as a function of the point spread function. In another embodiment, portions of the image data representative of the tagged stool are convolved with the point spread function to determine the fractional amount of stool present in the image portions, and the tagged stool subtracted by reducing the intensities of the associated portions of the image by an amount proportional to the fractional amount of stool present.
摘要:
An MRA image is corrected for motion artifacts using an iterative, autocorrection process in which corrections are tried and the quality of the resulting reconstructed image is measured. Corrections are made to the acquired three-dimensional data while the metric which measures image quality is applied to a two-dimensional projection image.
摘要:
Methods for measuring mechanical properties of an object or subject under examination with an ultrasound system and using unfocused ultrasound energy are provided. Shear waves that propagate in the object or subject are produced by applying unfocused ultrasound energy to the object or subject, and measurement data is acquired by applying focused or unfocused ultrasound energy to at least one location in the object or subject at which shear waves are present Mechanical properties are then calculated from the acquired measurement data.