-
21.发明授权公开(公告)号：US07919298B2
公开(公告)日：2011-04-05
申请号：US12393283
申请日：2009-02-26
申请人： Jesper Vind , Jurgen Carsten Franz Knotzel , Kim Borch , Allan Svendsen , Thomas Hoenger Callisen , Debbie Yaver , Mads Eskelund Bjoernvad , Peter Kamp Hansen
发明人： Jesper Vind , Jurgen Carsten Franz Knotzel , Kim Borch , Allan Svendsen , Thomas Hoenger Callisen , Debbie Yaver , Mads Eskelund Bjoernvad , Peter Kamp Hansen
CPC分类号： C12N9/20
摘要： The invention provides polypeptides obtained by introducing mutations in one or more regions identified in a parent lipase. The polypeptides of the present invention have surprisingly been found to have a low specific activity towards short chain fatty acids leading to a reduced odor generation and an increased BR over the lipases known in the art.
摘要翻译： 本发明提供通过在母体脂肪酶中鉴定的一个或多个区域中引入突变获得的多肽。 令人惊奇地发现本发明的多肽对短链脂肪酸具有低比活性，导致气味产生减少，并且在本领域已知的脂肪酶上增加BR。
-
公开(公告)号：US07465570B2
公开(公告)日：2008-12-16
申请号：US10556511
申请日：2004-04-29
CPC分类号： A21D8/042 , C12N9/18 , C12N9/20 , C12Y301/01032
摘要： The inventors have developed improved polypeptides by substituting or deleting specified amino acids in fungal lipolytic enzymes. More particularly, the polypeptides result in a reduction of dough stickiness when they are added to a dough. The polypeptides may particularly have activity on polar lipids.
摘要翻译： 本发明人通过在真菌脂肪分解酶中取代或缺失特定的氨基酸而开发了改进的多肽。 更具体地说，当将多肽加入面团时，多肽导致面团粘性降低。 多肽可以特别地对极性脂质具有活性。
-
公开(公告)号：US20080293120A1
公开(公告)日：2008-11-27
申请号：US12169679
申请日：2008-07-09
IPC分类号： C12N9/20
CPC分类号： A21D8/042 , C12N9/18 , C12N9/20 , C12Y301/01032
摘要： The inventors have developed improved polypeptides by substituting or deleting specified amino acids in fungal lipolytic enzymes. More particularly, the polypeptides result in a reduction of dough stickiness when they are added to a dough. The polypeptides may particularly have activity on polar lipids.
摘要翻译： 本发明人通过在真菌脂肪分解酶中取代或缺失特定的氨基酸而开发了改进的多肽。 更具体地说，当将多肽加入面团时，多肽导致面团粘性降低。 多肽可以特别地对极性脂质具有活性。
-
公开(公告)号：US07396657B2
公开(公告)日：2008-07-08
申请号：US11602553
申请日：2006-11-21
申请人： Signe Munk , Jesper Vind , Kim Borch , Shamkant Anant Patkar , Sanne O. Schroder Glad , Allan Svendsen
发明人： Signe Munk , Jesper Vind , Kim Borch , Shamkant Anant Patkar , Sanne O. Schroder Glad , Allan Svendsen
CPC分类号： C11D3/38627
摘要： Attaching a peptide extension to the C-terminal amino acid of a lipase reduces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile soiled with fat which includes relatively short-chain fatty acyl groups (e.g., up to C8) such as dairy stains containing butter fat or tropical oils such as coconut oil or palm kernel oil.
摘要翻译： 将肽延伸连接到脂肪酶的C末端氨基酸可降低形成气味的倾向。 当洗涤用脂肪污染的纺织品时，可能导致脂肪酶变体具有减少的气味产生，所述脂肪包括相对短链的脂肪酰基（例如高达C 8 N 8），例如含有脂肪或热带 油如椰子油或棕榈仁油。
-
公开(公告)号：US07157262B2
公开(公告)日：2007-01-02
申请号：US10232544
申请日：2002-08-30
申请人： Claus Crone Fuglsang , Jens Sigurd Okkels , Dorte Aaby Petersen , Shamkant Anant Patkar , Marianne Thellersen , Allan Svendsen , Kim Borch , John C. Royer , Titus Kretzschmar , Torben Halkier , Jesper Vind , Steen Troels Jorgensen
发明人： Claus Crone Fuglsang , Jens Sigurd Okkels , Dorte Aaby Petersen , Shamkant Anant Patkar , Marianne Thellersen , Allan Svendsen , Kim Borch , John C. Royer , Titus Kretzschmar , Torben Halkier , Jesper Vind , Steen Troels Jorgensen
CPC分类号： C11D3/38627 , C12N9/20
摘要： The present invention relates to a modified enzyme with lipolytic activity, a lipolytic enzyme capable of removing a substantial amount of fatty matter during a one cycle wash, a DNA sequence encoding said enzymes, a vector comprising said DNA sequence, a host cell harbouring said DNA sequence or said vector, and a process for producing said enzymes with lipolytic activity.
摘要翻译： 本发明涉及具有脂肪分解活性的修饰酶，能够在一次循环洗涤期间除去大量脂肪物质的脂肪分解酶，编码所述酶的DNA序列，包含所述DNA序列的载体，携带所述DNA的宿主细胞 序列或所述载体，以及用于产生具有脂肪分解活性的所述酶的方法。
-
公开(公告)号：US06495357B1
公开(公告)日：2002-12-17
申请号：US09007288
申请日：1998-01-14
申请人： Claus Crone Fuglsang , Jens Sigurd Okkels , Dorte Aaby Petersen , Shamkant Anant Patkar , Marianne Thellersen , Allan Svendsen , Kim Borch , John C. Royer , Titus Kretzschmar , Torben Halkier , Jesper Vind , Steen Troels Jorgensen
发明人： Claus Crone Fuglsang , Jens Sigurd Okkels , Dorte Aaby Petersen , Shamkant Anant Patkar , Marianne Thellersen , Allan Svendsen , Kim Borch , John C. Royer , Titus Kretzschmar , Torben Halkier , Jesper Vind , Steen Troels Jorgensen
IPC分类号： C12N920
CPC分类号： C11D3/38627 , C12N9/20
摘要： The present invention relates to a modified enzyme with lipolytic activity, a lipolytic enzime capable of removing a substantial amount of fatty matter a one cycle wash, a DNA sequence encoding said enzymes, a vector comprising said DNA sequence, a host cell harbouring said DNA sequence or said vector, and a process for producing said enzymes with lipolytic activity.
摘要翻译： 本发明涉及一种具有脂肪分解活性的修饰酶，能够一周期洗涤大量脂肪物质的脂肪分解酶，编码所述酶的DNA序列，包含所述DNA序列的载体，携带所述DNA序列的宿主细胞 或所述载体，以及用于产生具有脂肪分解活性的所述酶的方法。
-
公开(公告)号：US07879587B2
公开(公告)日：2011-02-01
申请号：US12443625
申请日：2007-10-02
申请人： Allan Svendsen , Jesper Vind , Shamkant Anant Patkar , Kim Borch
发明人： Allan Svendsen , Jesper Vind , Shamkant Anant Patkar , Kim Borch
CPC分类号： C12N9/20 , C07K2299/00
摘要： Variants with increased acyl transferase activity can be designed on the basis of a three-dimensional model by making amino acid alterations near the active Ser of lipolytic enzymes such as C. antarctica lipase A or the lipase/acyl transferase from C. parapsilosis.
摘要翻译： 具有增加的酰基转移酶活性的变体可以在三维模型的基础上通过在脂肪分解酶如南极洲洲脂肪酶A或来自副杆菌病的脂肪酶/酰基转移酶的活性Ser附近进行氨基酸改变来设计。
-
公开(公告)号：US20100003708A1
公开(公告)日：2010-01-07
申请号：US12443578
申请日：2007-10-02
申请人： Allan Svendsen , Jesper Vind , Shamkant Anant Patkar , Kim Borch
发明人： Allan Svendsen , Jesper Vind , Shamkant Anant Patkar , Kim Borch
CPC分类号： C12N9/20 , C07K2299/00
摘要： Lipolytic enzyme variants with increased specificity for short-chain fatty acids can be designed on the basis of a three-dimensional model of a lipolytic enzyme such as C. antarctica lipase A with a substrate analogue such as a fatty acid. An amino acid residue is selected within 10 Å of the carbon atom corresponding to the desired chain-length specificity, and the selected residue is substituted with a larger residue, or an amino acid insertion is made adjacent to the selected residue.
摘要翻译： 可以基于具有底物类似物如脂肪酸的南极洲脂肪酶A的脂肪分解酶的三维模型来设计对短链脂肪酸具有增加的特异性的脂肪分解酶变体。 在对应于所需链长度特异性的碳原子的10埃内选择氨基酸残基，并且所选择的残基被较大的残基取代，或者与选择的残基相邻地进行氨基酸插入。
-
公开(公告)号：US20090217464A1
公开(公告)日：2009-09-03
申请号：US12393136
申请日：2009-02-26
申请人： Philip Frank Souter , Neil Joseph Lant , Therese Clare Haynes , Jesper Vind , Kim Borch , Allan Svendsen , Robert Van der Lans , Lise Munch Mikkelsen , Christian Isak Jorgensen , Shamkant Anant Patkar
发明人： Philip Frank Souter , Neil Joseph Lant , Therese Clare Haynes , Jesper Vind , Kim Borch , Allan Svendsen , Robert Van der Lans , Lise Munch Mikkelsen , Christian Isak Jorgensen , Shamkant Anant Patkar
CPC分类号： C12N9/20 , C11D1/44 , C11D3/3788 , C11D3/38627
摘要： The invention provides detergent compositions comprising lipolytic enzyme variants having improved in-detergent stability. Lipolytic enzyme variants with improved in-detergent stability are obtained by substituting certain specified amino acid residues in a parent lipolytic enzyme.
摘要翻译： 本发明提供了包含具有改善的洗涤剂稳定性的脂肪分解酶变体的洗涤剂组合物。 通过用母体脂肪分解酶中的某些特定的氨基酸残基取代具有改善的洗涤剂稳定性的脂肪分解酶变体。
-
公开(公告)号：US20090217463A1
公开(公告)日：2009-09-03
申请号：US12393115
申请日：2009-02-26
申请人： Philip Frank Souter , Neil Joseph Lant , Theresa Clare Haynes , Jesper Vind , Jurgen Carsten Franz Knotzel , Kim Borch , Allan Svendsen , Thomas Honger Callisen , Debbie Yaver , Mads Eskelund Bjornvad , Peter Kamp Hansen
发明人： Philip Frank Souter , Neil Joseph Lant , Theresa Clare Haynes , Jesper Vind , Jurgen Carsten Franz Knotzel , Kim Borch , Allan Svendsen , Thomas Honger Callisen , Debbie Yaver , Mads Eskelund Bjornvad , Peter Kamp Hansen
CPC分类号： C12N9/20 , C11D3/38627
摘要： This invention relates to compositions comprising certain lipase enzymes and processes for making and using such compositions, including the use of such compositions to clean and/or treat a situs.
摘要翻译： 本发明涉及包含某些脂肪酶的组合物和制备和使用这些组合物的方法，包括使用这种组合物来清洁和/或治疗部位。
-
-
-
-
-
-
-
-
-
搜索结果
256 条记录 (耗时 0.054 秒)
