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公开(公告)号：US08273071B2
公开(公告)日：2012-09-25
申请号：US12587222
申请日：2009-10-01
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61M31/00
CPC分类号： A61M5/14276 , A61M2005/14513 , A61M2205/0244 , A61M2205/3523 , A61M2205/3569 , G05D7/0623 , G05D23/1917
摘要： Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
摘要翻译： 描述了包括远程控制物质输送装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据一些实施例，输送装置或相关装置可以放置在环境中，以便将材料泵入环境或装置内的附加流体处理结构。 示例性环境包括生物体，水体或封闭体积的流体。 被输送流体中物质的浓度可以通过遥控信号来改变。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。
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公开(公告)号：US08172833B2
公开(公告)日：2012-05-08
申请号：US12589847
申请日：2009-10-28
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22
CPC分类号： A61K9/0009 , A61M5/14276 , A61M5/145 , A61M5/172 , A61M5/1723 , A61M31/002 , A61M2005/14513 , A61M2205/0266 , A61M2205/0288 , A61M2205/3523 , A61M2205/3569 , A61M2205/36
摘要： Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
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公开(公告)号：US08109923B2
公开(公告)日：2012-02-07
申请号：US11505259
申请日：2006-08-15
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22
CPC分类号： A61K9/0004 , A61K9/0009 , A61K9/0024 , A61M5/14276 , A61M5/145 , A61M5/172 , A61M5/1723 , A61M2005/14513 , A61M2205/0266 , A61M2205/0288 , A61M2205/3523 , A61M2205/3569 , A61M2205/36 , A61N1/08
摘要： Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
摘要翻译： 描述了包括远程控制的渗透泵装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据一些实施例，将渗透泵装置放置在环境中以便将材料泵送到渗透泵装置内的环境或另外的流体处理结构中。 示例性环境包括生物体，水体或封闭体积的流体。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。
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公开(公告)号：US07699834B2
公开(公告)日：2010-04-20
申请号：US11302450
申请日：2005-12-13
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22
CPC分类号： A61K9/0004 , A61K9/0009 , A61K9/0024 , A61M5/14276 , A61M5/145 , A61M5/172 , A61M5/1723 , A61M2005/14513 , A61M2205/0266 , A61M2205/0288 , A61M2205/3523 , A61M2205/3569 , A61M2205/36 , A61N1/08
摘要： Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
摘要翻译： 描述了包括远程控制的渗透泵装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据一些实施例，将渗透泵装置放置在环境中以便将材料泵送到渗透泵装置内的环境或另外的流体处理结构中。 示例性环境包括生物体，水体或封闭体积的流体。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。
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公开(公告)号：US08998886B2
公开(公告)日：2015-04-07
申请号：US11302407
申请日：2005-12-13
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： A61K9/0004 , A61K9/0009 , A61K9/0024 , A61M5/14276 , A61M5/145 , A61M5/172 , A61M5/1723 , A61M2005/14513 , A61M2205/0266 , A61M2205/0288 , A61M2205/3523 , A61M2205/3569 , A61M2205/36 , A61N1/08
摘要： Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
摘要翻译： 描述了包括远程控制的渗透泵装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据一些实施例，将渗透泵装置放置在环境中以便将材料泵送到渗透泵装置内的环境或另外的流体处理结构中。 示例性环境包括生物体，水体或封闭体积的流体。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。
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公开(公告)号：US08585684B2
公开(公告)日：2013-11-19
申请号：US11271145
申请日：2005-11-09
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22
CPC分类号： A61M5/172 , A61K9/0009 , A61K9/0024 , A61K9/0097 , A61K41/00 , A61M5/14276 , A61M5/145 , A61M5/1723 , A61M2005/14513 , A61M2205/0266 , A61M2205/0288 , A61M2205/3523 , A61M2205/3569 , A61M2205/36 , A61M2205/52 , B01J19/0006 , B01J2219/00049 , C02F1/008 , C02F1/02 , C02F1/66 , C02F2101/20 , C02F2101/363 , C02F2209/02 , C12N9/0004 , C12N9/0006 , C12N9/10 , C12N9/12 , C12N9/14 , C12N9/88 , C12N9/90 , C12N9/93 , G08C17/02
摘要： Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various embodiments, a reaction device is placed in an environment in order to perform a chemical reaction in an environment. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
摘要翻译： 描述了包括遥控反应装置和相关控制器的系统的实施例。 还公开了装置的使用和控制方法。 根据各种实施方案，将反应装置置于环境中以在环境中进行化学反应。 示例性环境包括生物体，水体或封闭体积的流体。 在所选择的实施例中，可以使用磁场，电场或电磁控制信号。
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公开(公告)号：US08529551B2
公开(公告)日：2013-09-10
申请号：US11450159
申请日：2006-06-09
申请人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Leroy E. Hood , Muriel Y. Ishikawa , Edward K. Y. Jung , Robert Langer , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61M5/145 , A61M5/172 , A61M5/1723 , A61M2005/14513 , A61M2205/0266 , A61M2205/0288 , A61M2205/3507 , A61M2205/3523 , A61M2205/3569 , A61M2205/36
摘要： Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, an acoustic control signal may be used.
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公开(公告)号：US09617157B2
公开(公告)日：2017-04-11
申请号：US12322367
申请日：2009-01-30
申请人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Mahalaxmi Gita Bangera , Ed Harlow , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC分类号： C07K16/32 , A61K38/1703 , A61K38/1732 , A61K47/60 , A61K47/6871 , A61K47/6901 , B82Y5/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B21/0648 , C01B32/168 , C01B32/174 , C01B2202/02 , C01B2202/34 , C01B2202/36 , C01P2004/13 , Y02A50/473 , Y10S977/743 , Y10S977/75 , Y10S977/762 , Y10S977/788 , Y10S977/795 , Y10S977/848 , Y10S977/896 , Y10S977/915
摘要： Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.
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公开(公告)号：US08684898B2
公开(公告)日：2014-04-01
申请号：US12012218
申请日：2008-01-30
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61N5/00
CPC分类号： C09K11/06 , A61K9/0009
摘要： A method composition and system respond to ionizing, radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.
摘要翻译： 一种方法组成和系统响应电离，辐射来调节生物活性。 在一些方法中，电离辐射是产生引发生物活性反应的发光反应的X射线或极紫外辐射。
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公开(公告)号：US08529426B2
公开(公告)日：2013-09-10
申请号：US12012220
申请日：2008-01-30
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Nathan P. Myhrvold , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： A61N5/00
CPC分类号： A61K41/0057
摘要： A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.
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