公开(公告)号：US07765015B2

公开(公告)日：2010-07-27

申请号：US11622810

申请日：2007-01-12

申请人： Eric T. Johnson ,  Brian D. Soltis ,  Bruce A. Tockman ,  Peter J. D'aquanni ,  Kent C. B. Stalker ,  Gayla A. Smith

发明人： Eric T. Johnson ,  Brian D. Soltis ,  Bruce A. Tockman ,  Peter J. D'aquanni ,  Kent C. B. Stalker ,  Gayla A. Smith

IPC分类号： A61N1/05

CPC分类号： A61N1/057 ,  A61M25/04 ,  A61M25/10 ,  A61N2001/0585

摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.

摘要翻译： 构造成用于刺激心脏左侧（即，左心室）的医用电线。 在一个实施例中，引线包括包括内表面的细长引线主体。 可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面以固定远端 的铅。 引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。 内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

公开(公告)号：US20080071339A1

公开(公告)日：2008-03-20

申请号：US11855501

申请日：2007-09-14

申请人： Kent C. B. Stalker ,  Peter J. D'Aquanni ,  Eric T. Johnson

发明人： Kent C. B. Stalker ,  Peter J. D'Aquanni ,  Eric T. Johnson

IPC分类号： A61N1/05

CPC分类号： A61B5/0215 ,  A61B5/6876 ,  A61B2560/066 ,  A61M25/0074 ,  A61N1/05 ,  A61N2001/0578

摘要： An apparatus for releasably engaging an implantable medical device during delivery includes an elongate, tubular body having an open distal end a plurality of deflectable jaw members extending distally from the distal end of the body and terminating in distal tip portions, and an actuating member slidably disposed within the body and including a distal end portion operable to prevent inward deflection of the jaw members when positioned proximate the distal tip portions. The jaw members are adapted to releasably engage an engagement feature of the implantable medical device.

摘要翻译： 一种用于在输送过程中可释放地接合植入式医疗装置的装置包括细长的管状体，其具有开放的远端，多个可偏转的钳口构件从主体的远端向远侧延伸并且终止于远侧末端部分，以及可滑动地设置的致动构件 并且包括远端部分，其可操作以防止当邻近远侧末端部分定位时夹爪构件向内偏转。 钳口构件适于可释放地接合可植入医疗装置的接合特征。

公开(公告)号：US06833002B2

公开(公告)日：2004-12-21

申请号：US09885468

申请日：2001-06-19

申请人： Richard S. Stack ,  Udayan Patel ,  William J. Boyle ,  Kent C. B. Stalker ,  Paul F. Muller

发明人： Richard S. Stack ,  Udayan Patel ,  William J. Boyle ,  Kent C. B. Stalker ,  Paul F. Muller

IPC分类号： A61F206

CPC分类号： A61F2/966 ,  A61F2/95 ,  A61F2/958

摘要： A deformable sheath is attached to a catheter and introduced intravascularly to be expanded against an arterial wall and entrap plaque therebetween. A stent is subsequently deployed within the expanded sheath and the sheath is then withdrawn from within the vasculature to leave the stent expanded against the arterial wall with the plaque entrapped therebetween.

摘要翻译： 可变形护套附着在导管上，血管内引入以相对于动脉壁扩张并在其间夹带斑块。 随后将支架部署在扩张的护套内，然后从脉管系统中撤出护套，以使支架膨胀抵靠动脉壁，其间夹有斑块。

公开(公告)号：US06702834B1

公开(公告)日：2004-03-09

申请号：US09727102

申请日：2000-11-28

申请人： John F. Boylan ,  William J. Boyle ,  Andy E. Denison ,  Debashis Dutta ,  Benjamin C. Huter ,  Scott J. Huter ,  Paul F. Muller ,  Samir Patel ,  Christopher J. Tarapata ,  Chicheng Wang ,  Francisco Sanchez ,  Kent C. B. Stalker

发明人： John F. Boylan ,  William J. Boyle ,  Andy E. Denison ,  Debashis Dutta ,  Benjamin C. Huter ,  Scott J. Huter ,  Paul F. Muller ,  Samir Patel ,  Christopher J. Tarapata ,  Chicheng Wang ,  Francisco Sanchez ,  Kent C. B. Stalker

IPC分类号： A61M2900

CPC分类号： A61F2/013 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/008

摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.

摘要翻译： 一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。 该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。 在一个实施例中，过滤组件附接到导丝的远端，并且当导丝被操纵进入治疗区域时，其被布置在患者的脉管系统内。 以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。 此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。 介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。 其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

公开(公告)号：US06569193B1

公开(公告)日：2003-05-27

申请号：US09359550

申请日：1999-07-22

申请人： Daniel L. Cox ,  Kent C. B. Stalker ,  Joe Ventura, II

发明人： Daniel L. Cox ,  Kent C. B. Stalker ,  Joe Ventura, II

IPC分类号： A61F206

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2230/0013 ,  A61F2250/0039

摘要： A self-expanding, tapered profile stent for implantation in a body lumen, such as an artery, is disclosed. The stent is constructed of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in the longitudinal direction. The lengths of the cylindrical elements increase from one end of the stent to the opposite end by increasing the lengths of the struts and the lengths of the interconnecting members. Each cylindrical element is formed from repeating patterns of upright V's and inverted V's connected by straight strut arms with shoulders to create an overall serpentine wave pattern around the circumference. A step, continuous, parabolic, or curved taper in the stent can be imparted by using an expansion mandrel and applying deforming forces to the stent. The stent is made from pseudoelastic and shape memory alloys.

摘要翻译： 公开了一种用于植入体腔（例如动脉）中的自扩张锥形轮廓支架。 所述支架由多个可径向扩张的圆柱形元件构成，所述多个可径向扩张的圆柱形元件通常在公共纵向支架轴线上对准并且通过一个或多个相互连接的构件相互连接，以使支架在纵向方向上具有柔性。 通过增加支柱的长度和互连构件的长度，圆柱形元件的长度从支架的一端增加到相对端。 每个圆柱形元件由具有肩部的直的支撑臂连接的直立V和倒V的重复图案形成，以围绕圆周产生整体蛇形波形图案。 可以通过使用扩张心轴并向支架施加变形力来赋予支架中的台阶，连续，抛物线或弯曲的锥度。 支架由假弹性和形状记忆合金制成。

公开(公告)号：US06485500B1

公开(公告)日：2002-11-26

申请号：US09531740

申请日：2000-03-21

申请人： Arkady Kokish ,  Daryush Mirzaee ,  Eric J. Penn ,  Benjamin C. Huter ,  Kent C. B. Stalker ,  Gregg A. Jackson

发明人： Arkady Kokish ,  Daryush Mirzaee ,  Eric J. Penn ,  Benjamin C. Huter ,  Kent C. B. Stalker ,  Gregg A. Jackson

IPC分类号： A61M2900

CPC分类号： A61M25/104 ,  A61M2025/0079 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1093 ,  A61M2025/1095

摘要： The emboli protection system provides one or more inflatable blocking balloons for isolation of a section of a blood vessel to prevent migration of emboli from the section during an interventional procedure, and fluid infusion and evacuation ports for flushing emboli from the isolated section. One embodiment provides for a distal blocking balloon catheter, over which an interventional device can be introduced, and a proximal blocking balloon catheter to be introduced over the interventional device for isolating a portion of a blood vessel to be treated. The blocking balloons can be perforated to provide the infusion ports, and thrombolytic inflation fluid may be used to break down and dissolve thrombus and plaque in the isolated portion of the blood vessel. The interventional therapeutic device such as an angioplasty balloon catheter may be incorporated into the distal blocking balloon catheter, or the distal and blocking proximal balloon catheters can be incorporated with the interventional therapeutic device together in one device. Infusion ports may also be provided in either or both of the distal and proximal blocking catheters.

摘要翻译： 栓塞保护系统提供一个或多个可膨胀的阻塞气球，用于隔离血管的一部分，以防止在介入手术过程中栓塞从该部分移位，以及用于从隔离部分冲洗栓塞的流体输注和排出口。 一个实施例提供远端阻塞气囊导管，介入装置可以在其上引入，以及近端阻塞气囊导管，其被引入到介入装置上，用于隔离待治疗血管的一部分。 阻塞气囊可以被穿孔以提供输注口，并且可以使用溶栓膨胀流体来分解和溶解血管的孤立部分中的血栓和斑块。 诸如血管成形术气囊导管的介入治疗装置可以并入到远端阻塞气囊导管中，或者远端和阻塞近端球囊导管可以与介入治疗装置并入一个装置中。 输液口也可以设置在远端和近端阻塞导管中的一个或两者中。

公开(公告)号：US09220615B2

公开(公告)日：2015-12-29

申请号：US13403793

申请日：2012-02-23

申请人： Andy Edward Denison ,  Mark C. Bates ,  Kent C. B. Stalker

发明人： Andy Edward Denison ,  Mark C. Bates ,  Kent C. B. Stalker

IPC分类号： A61F2/06 ,  A61F2/88 ,  A61F2/89 ,  A61F2/915 ,  A61F2/82

CPC分类号： A61F2/89 ,  A61F2/88 ,  A61F2/915 ,  A61F2002/828 ,  A61F2002/91575 ,  A61F2002/91591 ,  A61F2250/0071

摘要： A stent may include a connector having a first portion, a second portion, and a third portion positioned between the first and second portions. The connector may be configured to interconnect axially adjacent stent segments. The connector may be further configured such that the third portion severs in response to a threshold amount of axial force, axial foreshortening, and/or cyclic loading or fatigue, in order to predispose the severance of one or more pre-configured connectors in a controlled manner to minimize any potential harm to the surrounding vasculature of a patient.

摘要翻译： 支架可以包括具有第一部分，第二部分和位于第一和第二部分之间的第三部分的连接器。 连接器可以被配置为将轴向相邻的支架段相互连接。 连接器可以被进一步配置成使得第三部分响应于轴向力的阈值量，轴向缩短和/或循环加载或疲劳而切断，以便使一个或多个预配置的连接器在被控制的连接器中的切断 以尽量减少对患者周围脉管系统的潜在危害。

公开(公告)号：US20070293922A1

公开(公告)日：2007-12-20

申请号：US11424349

申请日：2006-06-15

申请人： Brian D. Soltis ,  Bruce A. Tockman ,  Kent C. B. Stalker ,  Eric T. Johnson ,  Peter J. D'Aquanni

发明人： Brian D. Soltis ,  Bruce A. Tockman ,  Kent C. B. Stalker ,  Eric T. Johnson ,  Peter J. D'Aquanni

IPC分类号： A61N1/00

CPC分类号： A61N1/056 ,  A61N1/057 ,  A61N2001/0585

摘要： Medical electrical leads are provided including fixation features for acute and chronic fixation of a portion of the respective leads within the cardiac venous system. The medical electrical lead includes an elongate body having proximal and distal regions. Tissue contacting portions are selectively located in the distal region to contact an inner surface of the cardiac vessel when the lead is in an implanted position. The tissue contacting portion(s) include fixation features adapted to frictionally engage the inner surface of the cardiac vessel and promote tissue in-growth for chronic fixation. In some embodiments, the fixation features are detachable from the lead such that the lead can be extracted from its implanted position after tissue in-growth occurs.

摘要翻译： 提供了医疗电引线，其包括用于心脏静脉系统内的各个引线的一部分的急性和慢性固定的固定特征。 医疗电线包括具有近端和远端区域的细长体。 当引线处于植入位置时，组织接触部分选择性地位于远端区域中以接触心脏血管的内表面。 组织接触部分包括适于摩擦地接合心脏血管的内表面并促进用于慢性固定的组织生长的固定特征。 在一些实施例中，固定特征可从铅脱离，使得在组织生长发生之后，引线可以从其植入位置提取。

公开(公告)号：US07217255B2

公开(公告)日：2007-05-15

申请号：US10386071

申请日：2003-03-10

申请人： William J. Boyle ,  Andy E. Denison ,  Benjamin C. Huter ,  Scott J. Huter ,  Richard S. Stack ,  Kent C. B. Stalker ,  Christopher Tarapata ,  John D. Whitfield

发明人： William J. Boyle ,  Andy E. Denison ,  Benjamin C. Huter ,  Scott J. Huter ,  Richard S. Stack ,  Kent C. B. Stalker ,  Christopher Tarapata ,  John D. Whitfield

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/008

摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.

摘要翻译： 一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。 该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。 在一个实施例中，过滤组件附接到导丝的远端，并且当导丝被操纵进入治疗区域时，其被布置在患者的脉管系统内。 以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。 此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。 介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。 其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

公开(公告)号：US06540722B1

公开(公告)日：2003-04-01

申请号：US09490319

申请日：2000-01-24

申请人： William J. Boyle ,  Andy E. Denison ,  Benjamin C. Huter ,  Scott J. Huter ,  Richard S. Stack ,  Kent C. B. Stalker ,  Christopher Tarapata ,  John D. Whitfield

发明人： William J. Boyle ,  Andy E. Denison ,  Benjamin C. Huter ,  Scott J. Huter ,  Richard S. Stack ,  Kent C. B. Stalker ,  Christopher Tarapata ,  John D. Whitfield

IPC分类号： A61M2900

CPC分类号： A61F2/013 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/008

摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.

摘要翻译： 一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。 该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。 在一个实施例中，过滤组件附接到导丝的远端，并且当导丝被操纵进入治疗区域时，其被布置在患者的脉管系统内。 以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。 此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。 介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。 其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。