公开(公告)号：US20160022484A1

公开(公告)日：2016-01-28

申请号：US14341752

申请日：2014-07-25

Applicant: NOVARTIS AG

Inventor： Lingfeng Yu ,  Hugang Ren

IPC: A61F9/007 ,  A61B3/10 ,  A61B19/00

Abstract: An OCT-augmented surgical instrument able to correct for undesired movement, as well as a system for use with such a surgical instrument and a method of correcting for undesired movement during surgery using OCT.

Abstract translation: 能够纠正不期望的运动的OCT增强的外科器械以及用于这种外科器械的系统以及在使用OCT的手术期间校正不希望的运动的方法。

公开(公告)号：US10533838B2

公开(公告)日：2020-01-14

申请号：US16519169

申请日：2019-07-23

Applicant: Novartis AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: G01B9/02 ,  A61B3/15 ,  A61B3/10 ,  A61B3/14 ,  A61B3/00 ,  G01J9/02

Abstract: The present disclosure provides a visualization system for performing optimized optical coherence tomography (OCT) by determining the absolute distance between the OCT source and a sample. The present disclosure also provides a method for optimizing OCT, which includes determining an absolute distance between the OCT source and a sample using data relating to the focal length or position of an autofocus imager lens.

公开(公告)号：US10409051B2

公开(公告)日：2019-09-10

申请号：US15643170

申请日：2017-07-06

Applicant: Novartis AG

Inventor： Hugang Ren ,  Lingfeng Yu ,  Tammo Heeren

IPC: G06K9/00 ,  G02B21/36 ,  G06K9/62 ,  G02B21/02 ,  G06T7/60 ,  G06K9/46 ,  G02B21/00 ,  G06T7/80

Abstract: A method and system for extracting the zoom level of a microscope is disclosed. The method includes capturing a reference image; recording a first zoom level corresponding to a first magnification at which the reference image is captured; capturing a second image; determining a second zoom level by comparing the second image and the reference image, the second zoom level corresponding to a second magnification at which the second image is captured; and recording the second zoom level at a location accessible by a microscope application.

公开(公告)号：US20190069776A1

公开(公告)日：2019-03-07

申请号：US16177946

申请日：2018-11-01

Applicant: Novartis AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: A61B3/10 ,  G06T7/00 ,  A61B3/00 ,  A61B3/12

Abstract: A method of automatically detecting a retinal feature using an ophthalmic imaging system and automatically providing at least one of an audio, visual, and tactile indication of the detected retinal feature to a user.

公开(公告)号：US20180104100A1

公开(公告)日：2018-04-19

申请号：US15717171

申请日：2017-09-27

Applicant: Novartis AG

Inventor： Mauricio Jochinsen ,  Hugang Ren ,  Lingfeng Yu

IPC: A61F9/008

Abstract: An optical coherence tomography (OCT) system and method for cross view imaging using at least two B-scan images transformed and coupled to each other at an angle to generate a cross view image.

公开(公告)号：US09675244B1

公开(公告)日：2017-06-13

申请号：US14957306

申请日：2015-12-02

Applicant: Novartis AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: A61B3/14 ,  A61B3/00 ,  A61B3/10 ,  A61B3/13 ,  A61B34/20

CPC classification number: A61B3/102 ,  A61B3/0025 ,  A61B3/0058 ,  A61B3/13 ,  A61B3/14 ,  A61B3/18 ,  A61B34/20 ,  A61B2034/2055 ,  G02B21/0012

Abstract: An ophthalmic visualization system can include a computing device in communication with an OCT system configured to scan a surgical field to generate an OCT image. The computing device can be configured to determine locations within the surgical field corresponding to locations within the OCT image. The ophthalmic visualization system can also include an indicator mechanism in communication with the computing device and a surgical microscope configured to image the surgical field. The indicator mechanism can be configured to cause a location indicator to be positioned within a field of view of the surgical microscope. The location indicator can graphically represent the locations within the surgical field corresponding to the locations within the OCT image.

公开(公告)号：US09645379B2

公开(公告)日：2017-05-09

申请号：US14584685

申请日：2014-12-29

Applicant: NOVARTIS AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: A61B3/10 ,  G02B21/22 ,  A61B19/00 ,  A61B3/00 ,  A61B3/13

CPC classification number: G02B21/22 ,  A61B3/0058 ,  A61B3/12 ,  A61B3/132 ,  A61B90/20 ,  A61B2034/2065 ,  A61B2090/365 ,  G02B21/0012

Abstract: An ophthalmic visualization system can include an imaging device configured to acquire images of a surgical field; a computing device configured to determine an area of interest based on the images; and a display device in communication with the computing device and a surgical microscope, wherein the display device is configured to provide a graphical overlay onto at least a portion of a field of view of the surgical microscope, and wherein the graphical overlay includes a magnified image of the area of interest. A method of visualizing an ophthalmic procedure can include receiving images of a surgical field acquired by an imaging device; identifying an area of interest; generating a graphical overlay including a magnified image of the area of the interest; and outputting the graphical overlay to a display device such that the graphical overlay is positioned over a field of view of a surgical microscope.

公开(公告)号：US20170079521A1

公开(公告)日：2017-03-23

申请号：US14858541

申请日：2015-09-18

Applicant: NOVARTIS AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: A61B3/00 ,  A61B3/13 ,  A61B3/10

CPC classification number: A61B3/0025 ,  A61B3/102 ,  A61B3/13

Abstract: Optical coherence tomography (OCT) scan data is used to automatically detect and characterize vitreoretinal membranes in a spatially precise manner to generate a mask image. The mask image may characterize various aspects of a vitreoretinal membrane. The mask image is then overlaid with an optical image of the retina to enable visualization of the vitreoretinal membrane.

公开(公告)号：US20160331584A1

公开(公告)日：2016-11-17

申请号：US14712186

申请日：2015-05-14

Applicant: Novartis AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: A61F9/007 ,  A61B3/13 ,  A61B34/00 ,  A61B90/20 ,  A61B34/20

CPC classification number: A61F9/007 ,  A61B3/13 ,  A61B34/20 ,  A61B34/25 ,  A61B90/20 ,  A61B2017/00207 ,  A61B2034/2048 ,  A61B2034/2055 ,  A61B2034/2065 ,  A61B2034/254 ,  A61B2090/371 ,  A61B2090/372 ,  A61F9/00736 ,  G06F1/163 ,  G06F3/011 ,  G06F3/017 ,  G06F3/0482

Abstract: A surgical system uses a surgical tool as a control input. A tracking unit tracks a motion of the surgical tool, and a processing unit for processes the motion of the surgical tool to obtain a temporal spatial information of the surgical tool. The control unit further comprises a control input unit with a number of control commands. The control input unit associates the temporal spatial information of the surgical tool with a corresponding control command.

Abstract translation: 手术系统使用外科手术工具作为控制输入。 跟踪单元跟踪手术工具的运动，以及处理单元，用于处理外科工具的运动以获得手术工具的时间空间信息。 控制单元还包括具有多个控制命令的控制输入单元。 控制输入​​单元将外科手术工具的时间空间信息与相应的控制命令相关联。

公开(公告)号：US20190164294A1

公开(公告)日：2019-05-30

申请号：US16199423

申请日：2018-11-26

Applicant: Novartis AG

Inventor： Hugang Ren

IPC: G06T7/174 ,  G06T7/12 ,  G06T5/50 ,  G06T7/11

Abstract: A method for improving segmentation in optical coherence tomography imaging. The method comprises obtaining an OCT image of imaged tissue, generating a first feature image for at least a portion of the OCT image, and generating a second feature image for at least the portion of the OCT image, based on either the OCT image or the first feature image, by integrating image data in a first direction across the OCT image or first feature image. A third feature image is generated as a mathematical function of the first and second feature images, and layer segmentation for the OCT image is performed, based on the third feature image.