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    Methods and compositions for vitamin K epoxide reductase
    22.
    发明授权
    Methods and compositions for vitamin K epoxide reductase 有权
    维生素K环氧化物还原酶的方法和组成

    公开(公告)号：US08097410B2

    公开(公告)日：2012-01-17

    申请号：US11924707

    申请日：2007-10-26

    申请人： Darrel W. Stafford ,  Tao Li

    发明人： Darrel W. Stafford ,  Tao Li

    IPC分类号： C12Q1/68 ,  C07H21/02 ,  C07H21/04 ,  C12P19/24

    CPC分类号： C12N15/1137 ,  C12N9/0006 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/172

    摘要： The present invention provides a method of identifying a human subject having increased or decreased sensitivity to warfarin, comprising detecting in the subject the presence of a single nucleotide polymorphism in the VKOR gene, wherein the single nucleotide polymorphism is correlated with increased or decreased sensitivity to warfarin, thereby identifying the subject having increased or decreased sensitivity to warfarin.

    摘要翻译： 本发明提供了鉴定具有对华法林的敏感性增加或降低的人类受试者的方法，其包括在受试者中检测VKOR基因中单核苷酸多态性的存在，其中单核苷酸多态性与对华法林的敏感性增加或降低相关 ，从而鉴定对华法林的敏感性增加或降低的受试者。

    Sky detection system used in image extraction device and method using sky detection system
    25.
    发明申请
    Sky detection system used in image extraction device and method using sky detection system 有权
    天文检测系统用于图像提取装置和方法采用天空检测系统

    公开(公告)号：US20100322510A1

    公开(公告)日：2010-12-23

    申请号：US12801322

    申请日：2010-06-03

    申请人： Xun Yuan ,  Tao Li ,  Gang Wang ,  Zhongchao Shi

    发明人： Xun Yuan ,  Tao Li ,  Gang Wang ,  Zhongchao Shi

    IPC分类号： G06K9/00

    CPC分类号： G06K9/00697 ,  G06K9/6269

    摘要： Disclosed is a sky detection system that detects sky in an image collection device. The system includes an image collection unit that collects information of a color image; a color-feature extraction unit that extracts a color feature of each pixel from the collected image; a distance measurement unit that measures a distance between each pixel of the collected image and a lens; a first classification unit that classifies each pixel of the collected image as either a sky pixel or a non-sky pixel based on the color feature; and a second classification unit that further classifies each pixel of the collected image as either the sky pixel or the non-sky pixel based on the distance and a result of the first classification unit.

    摘要翻译： 公开了一种在图像采集装置中检测天空的天体检测系统。 该系统包括：图像收集单元，其收集彩色图像的信息; 颜色特征提取单元，从所收集的图像中提取每个像素的颜色特征; 距离测量单元，其测量所收集的图像的每个像素与透镜之间的距离; 第一分类单元，其基于颜色特征将所收集的图像的每个像素分类为天空像素或非天空像素; 以及第二分类单元，其基于距离和第一分类单元的结果将所收集的图像的每个像素进一步分类为天空像素或非天空像素。

    System and method for portable multimedia network learning machine and remote information transmission thereof
    27.
    发明授权
    System and method for portable multimedia network learning machine and remote information transmission thereof 失效
    便携式多媒体网络学习机的系统和方法及其远程信息传输

    公开(公告)号：US07840632B2

    公开(公告)日：2010-11-23

    申请号：US11718757

    申请日：2005-06-20

    申请人： Wei Zheng ,  Tao Li

    发明人： Wei Zheng ,  Tao Li

    IPC分类号： G06F15/16

    CPC分类号： G09B5/06 ,  G09B5/00 ,  G09B7/00

    摘要： A kind of portable multimedia network learning machine, includes a microprocessor and a memory connected to the microprocessor, input unit and display, communication and download module, multimedia driving device and multimedia player. The said communication and download module are used for communicating with the calculator connected to the hand-held multimedia network learning machine, uploading effectiveness of instruction message file, and may download multimedia cartoon menu file and multimedia packages in step with teaching in the far end database server, transmit learning situation result to the learning situation receiving terminal. While multimedia driving device and multimedia player are used for driving and playing the said downloaded cartoon menu file and courseware. The present invention also provides a kind of system and method realizing remote information transition between hand-held multimedia network learning machines. The present invention also provides a kind of method for producing multimedia document which can be played in the hand-held multimedia network learning machine. The present invention could expediently produce multimedia document or swap data with remote server.

    摘要翻译： 一种便携式多媒体网络学习机，包括微处理器和连接到微处理器的存储器，输入单元和显示器，通信和下载模块，多媒体驱动器件和多媒体播放器。 所述通信和下载模块用于与连接到手持多媒体网络学习机的计算机进行通信，上传指令消息文件的有效性，并且可以在远端数据库的教学中下载多媒体卡通菜单文件和多媒体包 服务器，将学习情况传递给接收终端的学习情况。 虽然多媒体驱动装置和多媒体播放器用于驾驶和播放所述下载的卡通菜单文件和课件。 本发明还提供一种实现手持多媒体网络学习机之间的远程信息转换的系统和方法。 本发明还提供了可以在手持式多媒体网络学习机中播放的多媒体文档的制作方法。 本发明可以方便地生成与远程服务器的多媒体文档或交换数据。

    Fused bicycloheterocycle substituted quinuclidine derivatives
    30.
    发明授权
    Fused bicycloheterocycle substituted quinuclidine derivatives 有权
    稠合双环杂环取代的奎宁环衍生物

    公开(公告)号：US07674794B2

    公开(公告)日：2010-03-09

    申请号：US11599651

    申请日：2006-11-15

    申请人： Jianguo Ji ,  Tao Li

    发明人： Jianguo Ji ,  Tao Li

    IPC分类号： A61K31/4375 ,  A61K31/55

    CPC分类号： A61K31/506 ,  A61K31/501 ,  A61K31/55 ,  C07D453/02

    摘要： Compounds of formula (I) wherein n is 0, 1, or 2; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.

    摘要翻译： 其中n为0,1或2的式（I）化合物; X是O，S，-NH-和-N-烷基 - ; Ar1是6元芳环; 并且Ar 2是稠合的双环杂环。 该化合物可用于治疗由α7nAChR配体预防或改善的病症或病症。 还公开了具有式（I）化合物的药物组合物和使用这些化合物和组合物的方法。