摘要:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
摘要:
A wireless handheld communications device with a liquid crystal display, especially, a field sequential liquid crystal display, includes a visual notification for a powered up, inactive state. The visual notification is preferably through a light emitting diode that may be part of the backlighting system for the LCD or may be independent from the backlighting system. The waveforms, periodicity, colour selection, and colour sequencing may be customizable by one or both of the manufacturer and user.
摘要:
A mobile wireless communications device includes a housing and circuit board carried by the housing and includes radio frequency (RF) circuitry and a processor carried by the circuit board and operative with each other. A display connector for an LCD connector is mounted on the circuit board and adapted to be connected to a display. Display connection lines are carried by the circuit board and interconnect the display connector and processor for carrying signals from the processor to the display connector and a connected display. Filters are carried by the circuit board and connected to the display connection lines and reduce any interfering energy from the processor and display.
摘要:
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
摘要:
In a handheld computing device that includes a backlit display having a variable-intensity backlight, and a function key, a method for controlling an intensity of light produced by the backlight involves the steps of (1) setting the intensity to a first level sufficient for viewing information on the display under first ambient lighting; and (2) upon activation of the function key, setting the intensity to a second level sufficient for viewing information on the backlit display under second ambient lighting that is different than the first ambient lighting.
摘要:
A method of manufacturing a portable computing device, involves the steps of (1) maintaining a table comprising stimulus/response data for possible hardware components that may be interfaced in the computing device; (2) performing one manufacturing step in the manufacture of the portable computing device by interfacing one of the possible hardware components with one other component of the computing device; and (3) performing one other manufacturing step in the manufacture by: (i) applying a stimulus to the interfaced hardware component, and reading a response from the interfaced hardware component in response to the applied stimulus; (ii) identifying the interfaced hardware component from a correlation of the response with the stimulus/response data; and (iii) saving the identification as configuration data in the computing device.
摘要:
A portable computing device includes a housing having an external surface, and an event notifier, a display device, and a light controller disposed within the housing. The event notifier includes an event notification lamp, and a light conduit terminating at the external surface for conveying light between the event notification lamp and the external surface. The display device includes illumination means for improved visualization of information rendered on the display device. The light controller is coupled to the event notifier and the illumination means. The light controller is configured to determine the intensity of ambient light external to the housing via the light conduit, and to adjust the intensity of light emitted by the illumination means in accordance with the determined ambient light intensity.
摘要:
In a handheld computing device that includes a backlit display having a variable-intensity backlight, and a function key, a method for controlling an intensity of light produced by the backlight involves the steps of (1) setting the intensity to a first level sufficient for viewing information on the display under first ambient lighting; and (2) upon activation of the function key, setting the intensity to a second level sufficient for viewing information on the backlit display under second ambient lighting that is different than the first ambient lighting.
摘要:
The present invention provides compounds and methods that can be used to convert the intermmediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.