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公开(公告)号：US20120288907A1
公开(公告)日：2012-11-15
申请号：US13471339
申请日：2012-05-14
摘要： A method is disclosed for restoring a Glu+ phenotype to a PTS−/Glu− bacterial cell which was originally capable of utilizing a phosphotransferase transport system (PTS) for carbohydrate transport. Bacterial cells comprising the Glu+ phenotype have modified endogenous chromosomal regulatory regions which are operably linked to polynucleotides encoding galactose permeases and glucokinases.
摘要翻译： 公开了一种将Glu +表型恢复到最初能够利用磷酸转移酶转运系统（PTS）用于碳水化合物转运的PTS- / Glu-细菌细胞的方法。 包含Glu +表型的细菌细胞具有修饰的内源性染色体调节区，其可操作地连接到编码半乳糖通透酶和葡糖激酶的多核苷酸。
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公开(公告)号：US20090142843A1
公开(公告)日：2009-06-04
申请号：US11971341
申请日：2008-01-09
摘要： A method is disclosed for restoring a Glu+ phenotype to a PTS−/Glu− bacterial cell which was originally capable of utilizing a phosphotransferase transport system (PTS) for carbohydrate transport. Bacterial cells comprising the Glu+ phenotype have modified endogenous chromosomal regulatory regions which are operably linked to polynucleotides encoding galactose permeases and glucokinases.
摘要翻译： 公开了一种将Glu +表型恢复到最初能够利用磷酸转移酶转运系统（PTS）用于碳水化合物转运的PTS- / Glu-细菌细胞的方法。 包含Glu +表型的细菌细胞具有修饰的内源性染色体调节区，其可操作地连接到编码半乳糖通透酶和葡糖激酶的多核苷酸。
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公开(公告)号：US09296850B2
公开(公告)日：2016-03-29
申请号：US14605189
申请日：2015-01-26
申请人： Frank J. Feher , Gregory M. Whited , Gopal K. Chotani , Fernando Valle , Carol Fioresi , Karl J. Sanford , Joseph McAuliffe , Marguerite Cervin , Aaron S. Puhala , Andrei Miasnikov , Ilana S. Aldor
发明人： Frank J. Feher , Gregory M. Whited , Gopal K. Chotani , Fernando Valle , Carol Fioresi , Karl J. Sanford , Joseph McAuliffe , Marguerite Cervin , Aaron S. Puhala , Andrei Miasnikov , Ilana S. Aldor
IPC分类号： C08F236/18 , C08F236/16 , C08F236/12 , C08F236/10 , C08F236/08 , C12P5/00 , C08F2/00 , C08F36/04 , C08F136/08 , C08L9/00 , C12P5/02 , C08F4/48
CPC分类号： C08F236/18 , C08F2/00 , C08F36/04 , C08F136/08 , C08F236/08 , C08F236/10 , C08F236/12 , C08L9/00 , C12P5/007 , Y10T436/24
摘要： It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has δ13C value of greater than −22%.
摘要翻译： 已经发现，培养物中的某些细胞可将大于约0.002％的细胞培养基中可用的碳转化为异戊二烯。 这些细胞具有异源核酸，其（i）编码异戊二烯合酶多肽，和（ii）可操作地连接于启动子。 然后可以回收在这种培养基中产生的异戊二烯并聚合成合成橡胶和其它有用的聚合物材料。 本发明的合成含异戊二烯的聚合物提供可证实为从非石化基础资源得到的益处。 它们也可以分析与来自天然来源的橡胶。 本发明更具体地公开了由衍生自异戊二烯单体的重复单元组成的聚异戊二烯聚合物，其中聚异戊二烯聚合物的δ13C值大于-22％。
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公开(公告)号：US20150203620A1
公开(公告)日：2015-07-23
申请号：US14605189
申请日：2015-01-26
申请人： Frank J. Feher , Gregory M. Whited , Gopal K. Chotani , Fernando Valle , Carol Fioresi , Karl J. Sanford , Joseph McAuliffe , Marguerite Cervin , Aaron S. Puhala , Andrei Miasnikov , Ilana S. Aldor
发明人： Frank J. Feher , Gregory M. Whited , Gopal K. Chotani , Fernando Valle , Carol Fioresi , Karl J. Sanford , Joseph McAuliffe , Marguerite Cervin , Aaron S. Puhala , Andrei Miasnikov , Ilana S. Aldor
IPC分类号： C08F236/18 , C08F236/10 , C08F236/12 , C08F136/08
CPC分类号： C08F236/18 , C08F2/00 , C08F36/04 , C08F136/08 , C08F236/08 , C08F236/10 , C08F236/12 , C08L9/00 , C12P5/007 , Y10T436/24
摘要： It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has δ13C value of greater than −22%.
摘要翻译： 已经发现，培养物中的某些细胞可将大于约0.002％的细胞培养基中可用的碳转化为异戊二烯。 这些细胞具有异源核酸，其（i）编码异戊二烯合酶多肽，和（ii）可操作地连接于启动子。 然后可以回收在这种培养基中产生的异戊二烯并聚合成合成橡胶和其它有用的聚合物材料。 本发明的合成含异戊二烯的聚合物提供可证实为从非石化基础资源得到的益处。 它们也可以分析与来自天然来源的橡胶。 本发明更具体地公开了由衍生自异戊二烯单体的重复单元组成的聚异戊二烯聚合物，其中聚异戊二烯聚合物的δ13C值大于-22％。
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公开(公告)号：US07456298B2
公开(公告)日：2008-11-25
申请号：US11646945
申请日：2006-12-28
IPC分类号： C07D317/50
CPC分类号： C12P9/00 , C07F7/081 , C07F7/0812 , C07F7/083 , C07F7/0896
摘要： The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for converting silane cis-diols to the corresponding catechols and the compounds produced thereby. The present invention also provides chemical methods for the conversion of said silane cis-diols and acetonide compounds to epoxy, saturated and otherwise modified derivatives. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译： 本发明涉及顺式二醇和生产顺式二醇的生物学方法。 本发明还涉及随后将这种硅烷顺式二醇转化为更稳定的丙酮化合物衍生物的方法，以及将硅烷顺式二醇转化成相应的儿茶酚及其制备的化合物的方法。 本发明还提供了将所述硅烷顺式二醇和丙酮化合物转化为环氧，饱和和其它改性衍生物的化学方法。 要强调的是，该摘要被提供以符合要求摘要的规则，这将允许搜索者或其他读者快速确定技术公开的主题。 提交的理解是不会用于解释或限制权利要求的范围或含义。
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公开(公告)号：US07179932B2
公开(公告)日：2007-02-20
申请号：US10453468
申请日：2003-06-03
IPC分类号： C07F7/04
CPC分类号： C12P9/00 , C07F7/081 , C07F7/0812 , C07F7/083 , C07F7/0896
摘要： The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for converting silane cis-diols to the corresponding catechols and the compounds produced thereby. The present invention also provides chemical methods for the conversion of said silane cis-diols and acetonide compounds to epoxy, saturated and otherwise modified derivatives. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims 37 CFR 1.72(b).
摘要翻译： 本发明涉及顺式二醇和生产顺式二醇的生物学方法。 本发明还涉及随后将这种硅烷顺式二醇转化为更稳定的丙酮化合物衍生物的方法，以及将硅烷顺式二醇转化成相应的儿茶酚及其制备的化合物的方法。 本发明还提供了将所述硅烷顺式二醇和丙酮化合物转化为环氧，饱和和其它改性衍生物的化学方法。 要强调的是，该摘要被提供以符合要求摘要的规则，这将允许搜索者或其他读者快速确定技术公开的主题。 提交的理由不会用于解释或限制权利要求的范围或意义37 CFR 1.72（b）。
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公开(公告)号：US07381830B2
公开(公告)日：2008-06-03
申请号：US11646784
申请日：2006-12-28
IPC分类号： C07F7/04
CPC分类号： C12P9/00 , C07F7/081 , C07F7/0812 , C07F7/083 , C07F7/0896
摘要： The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for converting silane cis-diols to the corresponding catechols and the compounds produced thereby. The present invention also provides chemical methods for the conversion of said silane cis-diols and acetonide compounds to epoxy, saturated and otherwise modified derivatives. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译： 本发明涉及顺式二醇和生产顺式二醇的生物学方法。 本发明还涉及随后将这种硅烷顺式二醇转化为更稳定的丙酮化合物衍生物的方法，以及将硅烷顺式二醇转化成相应的儿茶酚及其制备的化合物的方法。 本发明还提供了将所述硅烷顺式二醇和丙酮化合物转化为环氧，饱和和其它改性衍生物的化学方法。 要强调的是，该摘要被提供以符合要求摘要的规则，这将允许搜索者或其他读者快速确定技术公开的主题。 提交的理解是不会用于解释或限制权利要求的范围或含义。
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28.发明授权Composition comprising various proteorhodopsins and/or bacteriorhodopsins and use thereof 有权包含各种蛋白质视紫红质和/或细菌视紫红质的组合物及其用途公开(公告)号：US07982000B2
公开(公告)日：2011-07-19
申请号：US11569862
申请日：2005-06-09
申请人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward, II , Gregory M. Whited
发明人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward, II , Gregory M. Whited
IPC分类号： C07K17/00 , G11B11/00 , G11B7/085 , G11B7/00 , G11B5/84 , G11B7/24 , B32B3/02 , G03F7/00 , G02F1/09
CPC分类号： G11C7/00 , C07K14/215 , C09D11/037 , C09D11/50 , G11B7/242 , Y10S430/146 , Y10T428/249921 , Y10T428/31623 , Y10T428/31685 , Y10T428/31725 , Y10T428/31783
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.
摘要翻译： 本发明提供了一种固体材料，其包含两种或多种蛋白质视紫红质，两种或更多种细菌视紫红质，或一种或多种细菌视紫红质和一种或多种蛋白质视紫质的固定化混合物。 蛋白质视紫红质选自全反式视黄醛的蛋白质视黄素和含视网膜类似物的蛋白质视紫红质; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自全反式视网膜含细菌视紫红质和视网膜类似物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料的基材 和塑料材料，其中所述固体材料沉积在所述基底上。 本发明还提供了包含一种或多种亲水聚合物和各种光致变色材料的混合物的安全油墨。
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29.发明申请Composition Comprising Various Proteorhodopsins and/or Bacteriorhodopsins and Use Thereof 有权包含各种蛋白质视紫红质和/或细菌视紫红质及其用途的组合物公开(公告)号：US20080292828A1
公开(公告)日：2008-11-27
申请号：US11569862
申请日：2005-06-09
申请人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward, II , Gregory M. Whited
发明人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward, II , Gregory M. Whited
IPC分类号： C08L89/00 , C07K14/195 , B32B27/00
CPC分类号： G11C7/00 , C07K14/215 , C09D11/037 , C09D11/50 , G11B7/242 , Y10S430/146 , Y10T428/249921 , Y10T428/31623 , Y10T428/31685 , Y10T428/31725 , Y10T428/31783
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.
摘要翻译： 本发明提供了一种固体材料，其包含两种或多种蛋白质视紫红质，两种或更多种细菌视紫红质，或一种或多种细菌视紫红质和一种或多种蛋白质视紫质的固定化混合物。 蛋白质视紫红质选自全反式视黄醛的蛋白质视黄素和含视网膜类似物的蛋白质视紫红质; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自全反式视网膜含细菌视紫红质和视网膜类似物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料的基材 和塑料材料，其中所述固体材料沉积在所述基底上。 本发明还提供了包含一种或多种亲水聚合物和各种光致变色材料的混合物的安全油墨。
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30.发明授权Composition comprising various proteorhodopsins and/or bacteriorhodopsins and use thereof 失效包含各种蛋白质视紫红质和/或细菌视紫红质的组合物及其用途公开(公告)号：US08372953B2
公开(公告)日：2013-02-12
申请号：US13181387
申请日：2011-07-12
申请人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward, II , Gregory M. Whited
发明人： Richard R. Bott , Rasmus B. Jensen , Bradley R. Kelemen , Donald E. Ward, II , Gregory M. Whited
CPC分类号： G11C7/00 , C07K14/215 , C09D11/037 , C09D11/50 , G11B7/242 , Y10S430/146 , Y10T428/249921 , Y10T428/31623 , Y10T428/31685 , Y10T428/31725 , Y10T428/31783
摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.
摘要翻译： 本发明提供了一种固体材料，其包含两种或多种蛋白质视紫红质，两种或更多种细菌视紫红质，或一种或多种细菌视紫红质和一种或多种蛋白质视紫质的固定化混合物。 蛋白质视紫红质选自全反式视黄醛的蛋白质视黄素和含视网膜类似物的蛋白质视紫红质; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自全反式视网膜含细菌视紫红质和视网膜类似物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料的基材 和塑料材料，其中所述固体材料沉积在所述基底上。 本发明还提供了包含一种或多种亲水聚合物和各种光致变色材料的混合物的安全油墨。
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