-
21.发明申请1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 有权用于治疗神经损伤性疾病的1-亚油基-4-氧 - 哌啶化合物公开(公告)号：US20150376205A1
公开(公告)日：2015-12-31
申请号：US14847703
申请日：2015-09-08
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Tatsuki KOIKE , Masato Yoshikawa , Haruhi Ando , William John Farnaby , Toshiya Nishi
IPC: C07D498/08 , C07D413/14 , C07D413/10 , C07D405/14 , C07D417/14 , C07D401/10 , C07D401/14
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
Abstract translation: 本发明提供可用作预防或治疗神经变性疾病等的药剂或其盐。 本发明涉及由式（I）表示的化合物，其中每个符号如说明书中所定义，或其盐。
-
公开(公告)号：US08940758B2
公开(公告)日：2015-01-27
申请号：US13944370
申请日：2013-07-17
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Takahiko Taniguchi , Masato Yoshikawa , Kasei Miura , Tomoaki Hasui , Eiji Honda , Keisuke Imamura , Makoto Kamata , Haruhi Ando
IPC: A61K31/4353 , A61K31/437 , A61K31/4355
CPC classification number: A61K31/4353 , A61K31/4355 , A61K31/437 , A61K31/4427 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/522 , A61K31/551 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14 , C07D471/04 , C07D471/14 , C07D473/00 , C07D473/28 , C07D487/04 , C07D495/04 , C07D498/04 , C07D498/08 , C07D519/00 , C07F7/10
Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as an agent for preventing or treating schizophrenia. The compound is represented by the formula (I): wherein the symbols are defined in the specification.
Abstract translation: 本发明提供具有PDE抑制作用的化合物，其可用作预防或治疗精神分裂症的药剂。 化合物由式（I）表示：其中符号在说明书中定义。
-
公开(公告)号：US08871766B2
公开(公告)日：2014-10-28
申请号：US13944042
申请日：2013-07-17
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: A61K31/50 , A61K31/501 , C07D405/14 , C07D413/14 , C07D413/10 , C07D401/10 , C07D498/08 , C07D401/14 , C07D417/14
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
Abstract translation: 本发明提供可用作预防或治疗神经变性疾病等的药剂或其盐。 本发明涉及由下式表示的化合物，其中每个符号如说明书中所定义，或其盐。
-
公开(公告)号：US08865717B2
公开(公告)日：2014-10-21
申请号：US13944000
申请日：2013-07-17
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: A61K31/50 , A61K31/501 , C07D413/14 , C07D417/14 , C07D413/10 , C07D401/10 , C07D401/14 , C07D498/08 , C07D405/14
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
-
公开(公告)号：US08648079B2
公开(公告)日：2014-02-11
申请号：US13633995
申请日：2012-10-03
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: A61K31/50 , A61K31/501
CPC classification number: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
-
Patent Agency Ranking
26.发明授权公开(公告)号：US10717748B2
公开(公告)日：2020-07-21
申请号：US16779797
申请日：2020-02-03
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
-
27.发明授权公开(公告)号：US10273245B2
公开(公告)日：2019-04-30
申请号：US16194540
申请日：2018-11-19
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby
IPC: C07D498/08 , C07D405/10 , C07D405/14 , C07D413/14 , C07D401/14 , C07D413/10 , C07D417/14 , C07D401/10
Abstract: The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
-
公开(公告)号：US09643957B2
公开(公告)日：2017-05-09
申请号：US14650429
申请日：2013-12-10
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Tatsuki Koike , Yuichi Kajita , Masato Yoshikawa , Shuhei Ikeda , Hiromi Fukuda
IPC: C07D403/12 , C07D471/08 , C07D491/08 , C07D213/12 , C07D498/08 , C07D405/12 , C07D401/14 , C07D417/14 , C07D451/04 , C07D487/10 , C07D405/14 , C07D413/14 , C07D401/04 , C07D401/12 , C07D239/42 , C07D413/04 , C07D417/04 , C07D451/02 , C07D487/18 , C07D491/18 , C07D403/04 , C07D403/14 , C07D471/10 , A61K9/20 , A61K9/48 , C07D213/72 , C07D487/08 , C12N9/99
CPC classification number: C07D498/08 , A61K9/2018 , A61K9/4858 , C07D213/12 , C07D213/72 , C07D213/74 , C07D239/42 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D451/02 , C07D451/04 , C07D471/08 , C07D471/10 , C07D487/08 , C07D487/10 , C07D487/18 , C07D491/08 , C07D491/18 , C12N9/99
Abstract: An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.
-
公开(公告)号：US09598398B2
公开(公告)日：2017-03-21
申请号：US14781963
申请日：2014-04-03
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby , Shuhei Ikeda , Yuichi Kajita , Toshiya Nishi
IPC: C07D401/14 , C07D403/14 , A61K31/497 , A61K31/4545 , A61K31/444 , C07D401/10 , C07D403/12 , C07D405/14 , C07D413/14 , C07D401/12 , C07D239/26 , C07D417/14 , C07D213/34 , C07D213/56 , C07D213/42
CPC classification number: C07D401/10 , C07D213/34 , C07D213/42 , C07D213/56 , C07D239/26 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14
Abstract: The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
-
30.发明授权公开(公告)号：US09226921B2
公开(公告)日：2016-01-05
申请号：US14253139
申请日：2014-04-15
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Takahiko Taniguchi , Masato Yoshikawa , Kasei Miura , Tomoaki Hasui , Eiji Honda , Keisuke Imamura , Makoto Kamata , John F. Quinn , Joseph Raker , Fatoumata Camara , Yi Wang
IPC: C07D401/10 , C07D401/14 , A61K31/437 , A61K31/4353 , A61K31/4355 , A61K31/4427 , A61K31/4985 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/522 , A61K31/551 , C07D403/04 , C07D403/14 , C07D413/14 , C07D471/04 , C07D471/14 , C07D473/28 , C07D487/04 , C07D495/04 , C07D498/04 , C07D498/08 , C07D519/00 , C07D473/00 , C07F7/10 , A61K31/4439 , A61K31/444
CPC classification number: A61K31/4353 , A61K31/4355 , A61K31/437 , A61K31/4427 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/522 , A61K31/551 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14 , C07D471/04 , C07D471/14 , C07D473/00 , C07D473/28 , C07D487/04 , C07D495/04 , C07D498/04 , C07D498/08 , C07D519/00 , C07F7/10
Abstract: The present invention provides a compound which has the effect of PDE inhibition, and which is useful as an agent for preventing or treating schizophrenia or so on represented by the formula (I):
Abstract translation: 本发明提供具有PDE抑制作用的化合物，其可用作预防或治疗由式（I）表示的精神分裂症等的药剂：
-
-
-
-
-
-
-
-
-
Search Results
36
records
(took 0.032 seconds)
