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公开(公告)号:US07749504B2
公开(公告)日:2010-07-06
申请号:US11733861
申请日:2007-04-11
申请人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号: A61K39/395 , C12P21/04 , C12P21/08 , C07K16/00
CPC分类号: G01N33/57484 , A61K47/60 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6839 , A61K47/6851 , A61K47/6859 , A61K51/1006 , A61K51/1018 , A61K2039/505 , C07K16/1072 , C07K16/18 , C07K16/30 , C07K16/303 , C07K2317/73 , C07K2317/76 , C07K2317/77
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US20090324490A1
公开(公告)日:2009-12-31
申请号:US12380124
申请日:2009-02-23
申请人: Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人: Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号: A61K51/10 , A61K39/395 , A61K39/00 , A61P35/00
CPC分类号: C07K16/18 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K16/30 , C07K16/3023 , C07K16/40 , C07K2317/73 , G01N33/57407
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20090246129A1
公开(公告)日:2009-10-01
申请号:US12323000
申请日:2009-02-09
申请人: Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillps , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人: Belinda Caims , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillps , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
IPC分类号: A61K51/10 , C12N5/02 , C12N9/96 , A61K39/395 , A61K39/00
CPC分类号: C07K16/18 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K16/30 , C07K16/3023 , C07K16/40 , C07K2317/73 , G01N33/57407
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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24.
公开(公告)号:US20090136928A1
公开(公告)日:2009-05-28
申请号:US11929250
申请日:2007-10-30
申请人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
发明人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth J. Hillan , Hartmut Koeppen , Heidi S. Phillips , Paul Polakis , Susan D. Spencer , Victoria Smith , P. Mickey Williams , Thomas D. Wu , Zemin Zhang
CPC分类号: C07K16/18 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K16/30 , C07K16/3023 , C07K16/40 , C07K2317/73 , G01N33/57407
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US20070048326A1
公开(公告)日:2007-03-01
申请号:US11538552
申请日:2006-10-04
申请人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth Hillan , Hartmut Koeppen , Heidi Phillips , Paul Polakis , Susan Spencer , Victoria Smith , P. Williams , Thomas Wu , Zemin Zhang
发明人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth Hillan , Hartmut Koeppen , Heidi Phillips , Paul Polakis , Susan Spencer , Victoria Smith , P. Williams , Thomas Wu , Zemin Zhang
IPC分类号: A61K39/395 , G01N33/574 , C07K16/30
CPC分类号: C07K16/18 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505 , C07K16/30 , C07K16/3023 , C07K16/40 , C07K2317/73 , G01N33/57407
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20050107595A1
公开(公告)日:2005-05-19
申请号:US10938061
申请日:2004-09-10
申请人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth Hillan , Hartmut Koeppen , Heidi Phillips , Paul Polakis , Susan Spencer , Victoria Smith , P. Williams , Thomas Wu , Zemin Zhang , Chie Sakanaka , Anan Chuntharapai , Chae Reed
发明人: Belinda Cairns , Ruihuan Chen , Gretchen Frantz , Kenneth Hillan , Hartmut Koeppen , Heidi Phillips , Paul Polakis , Susan Spencer , Victoria Smith , P. Williams , Thomas Wu , Zemin Zhang , Chie Sakanaka , Anan Chuntharapai , Chae Reed
CPC分类号: C07K16/18 , A61K2039/505 , C07K2317/77
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20070053835A1
公开(公告)日:2007-03-08
申请号:US11538764
申请日:2006-10-04
申请人: Frederic DeSauvage , Gretchen Frantz , Kenneth Hillan , Paul Polakis , Andrew Polson , Victoria Smith , Susan Spencer , Thomas Wu , Zemin Zhang
发明人: Frederic DeSauvage , Gretchen Frantz , Kenneth Hillan , Paul Polakis , Andrew Polson , Victoria Smith , Susan Spencer , Thomas Wu , Zemin Zhang
IPC分类号: A61K51/00 , A61K39/395 , C07K16/46 , C07K16/30
CPC分类号: C07K16/30 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20050064492A1
公开(公告)日:2005-03-24
申请号:US10948518
申请日:2004-09-22
申请人: Frederic DeSauvage , Gretchen Frantz , Kenneth Hillan , Paul Polakis , Andrew Polson , Victoria Smith , Susan Spencer , Thomas Wu , Zemin Zhang
发明人: Frederic DeSauvage , Gretchen Frantz , Kenneth Hillan , Paul Polakis , Andrew Polson , Victoria Smith , Susan Spencer , Thomas Wu , Zemin Zhang
IPC分类号: A61K47/48 , C07K16/30 , C12Q1/68 , C12P19/34 , G01N33/574
CPC分类号: C07K16/30 , A61K47/6803 , A61K47/6809 , A61K47/6843 , A61K47/6851 , A61K2039/505
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20080050377A1
公开(公告)日:2008-02-28
申请号:US10553491
申请日:2004-04-16
申请人: Heidi Ackerly , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
发明人: Heidi Ackerly , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
IPC分类号: C07K16/30 , A61K39/395 , A61P35/00 , C12N1/00 , C12N15/63 , G01N33/574 , G01N33/53 , C12N15/13 , C07K14/435 , C07K16/18
CPC分类号: C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
摘要: The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.
摘要翻译: 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽,抗体,拮抗剂,激动剂,增效剂,核酸分子,与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。
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公开(公告)号:US20110112279A1
公开(公告)日:2011-05-12
申请号:US12845470
申请日:2010-07-28
申请人: HEIDI ACKERLY , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
发明人: HEIDI ACKERLY , Avi Ashkenazi , David Eberhard , Gretchen Frantz , Dorothy French , Germaine G. Fuh , Jo-Anne S. Hongo , Chingwei V. Lee , Scot A. Marsters , Helga A. Raab , Evgeny Varfolomeev , Beni B. Wolf , Robert Maurice Pitti , Liliana Soroceanu
IPC分类号: C07K16/18
CPC分类号: C07K16/32 , C07K16/22 , C07K16/4283 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622
摘要: The present invention provides novel polypeptides, antibodies, antagonists, agonists, potentiators, nucleic acid molecules, compositions and methods relating to the STOP-1 polypeptide that are useful for treating and preventing diseases and for medical diagnosis and research. The present invention also provides consensus sequences and specific sequences for antibodies that specifically bind to STOP-1 that are useful in the methods described herein.
摘要翻译: 本发明提供了可用于治疗和预防疾病和医学诊断和研究的新型多肽,抗体,拮抗剂,激动剂,增效剂,核酸分子,与STOP-1多肽相关的组合物和方法。 本发明还提供了与本文所述方法有用的特异性结合STOP-1的抗体的共有序列和特异性序列。
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