HUMAN T2R RECEPTORS FOR RANITIDINE, STRYCHNINE AND DENATONIUM AND RELATED ASSAYS FOR IDENTIFYING HUMAN BITTER TASTE MODULATORS
    25.
    发明申请
    HUMAN T2R RECEPTORS FOR RANITIDINE, STRYCHNINE AND DENATONIUM AND RELATED ASSAYS FOR IDENTIFYING HUMAN BITTER TASTE MODULATORS 有权
    人类T2R受体的RANITIDINE,STRYCHNINE和DENATONIUM及相关测定用于鉴定人体双歧杆菌调味剂

    公开(公告)号:US20090087866A1

    公开(公告)日:2009-04-02

    申请号:US12166980

    申请日:2008-07-02

    IPC分类号: G01N33/567

    摘要: The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter ligands, i.e., acetaminophen, ranitidine, strychnine and denatonium. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors and which may be used as additives in foods, beverages and medicinals for modifying (blocking) T2R-associated bitter taste.

    摘要翻译: 本发明涉及T2R味觉受体家族中的特定人味受体对特定苦味配体即对乙酰氨基酚,雷尼替丁,士的宁和丹那铵的反应的发现。 本发明还涉及这些受体在用于鉴定调节这些味觉受体的活化的配体的测定中的用途,并且其可用作用于改变(阻断)T2R相关苦味的食品,饮料和药物中的添加剂。

    System and Method of Traffic Inspection and Stateful Connection Forwarding Among Geographically Dispersed Network Appliances Organized as Clusters
    26.
    发明申请
    System and Method of Traffic Inspection and Stateful Connection Forwarding Among Geographically Dispersed Network Appliances Organized as Clusters 有权
    作为集群组织的地域分散网络设备之间的交通检查和状态连接转发系统与方法

    公开(公告)号:US20090040926A1

    公开(公告)日:2009-02-12

    申请号:US11834576

    申请日:2007-08-06

    IPC分类号: G08C15/00

    摘要: A peering relationship among two or more network appliances is established through an exchange of control messages among the network appliances. The peering relationship defines a cluster of peered network appliances, and at each network appliance of the cluster traffic flow state information for all the network appliances of the cluster is maintained. Network traffic associated with traffic flows of the network appliances of the cluster is managed according to the state information for the traffic flows. This managing of the network traffic may include forwarding among the network appliances of the cluster (i.e., to those of the appliances handling the respective flows) at least some of the network traffic associated with one or more of the traffic flows according to the state information for the one or more traffic flows. The traffic flows may be TCP connections or UDP flows.

    摘要翻译: 通过网络设备之间的交换控制消息建立两个或多个网络设备之间的对等关系。 对等关系定义了一组对等网络设备,并且在群集的每个网络设备上维护集群的所有网络设备的流量状态信息。 根据业务流的状态信息管理与集群网络设备的流量相关联的网络流量。 网络流量的这种管理可以包括根据状态信息在集群的网络设备(即,处理各个流的设备的网络设备)之间转发与一个或多个业务流相关联的至少一些网络流量 为一个或多个交通流量。 流量可能是TCP连接或UDP流。

    ANTENNA DEVICE HAVING A NON-ELECTRICAL ENGAGEMENT DURING PRE-LOCK
    27.
    发明申请
    ANTENNA DEVICE HAVING A NON-ELECTRICAL ENGAGEMENT DURING PRE-LOCK 有权
    在预锁定期间进行非电气接合的天线装置

    公开(公告)号:US20080272969A1

    公开(公告)日:2008-11-06

    申请号:US11742902

    申请日:2007-05-01

    IPC分类号: H01Q1/32 H01R13/642

    摘要: An antenna device has an antenna main body, a fixing member and a bolt. The antenna main body comprises an antenna element, female connectors provided at a first connector, a female screw section, and an engagement claw inserted into an antenna mount hole to make engagement with a lower side face of a roof panel. A fixing member comprises cables, male connectors provided at a second connector, the male connectors being provided to make mechanical engagement with female connectors without an electrical connection, and being connected to the cable, and a male screw section helically fitted to a female screw section, thereby tightening the female connectors, the male connectors, and a roof panel with one another. A bolt may be mounted between the male and female connectors to allow electrical connection therebetween.

    摘要翻译: 天线装置具有天线主体,固定构件和螺栓。 天线主体包括天线元件,设置在第一连接器处的阴连接器,阴螺纹部分和插入天线安装孔中的接合爪,以与顶板的下侧面接合。 固定构件包括电缆,设置在第二连接器处的阳连接器,所述阳连接器设置成与阴连接器机械接合而没有电连接,并且连接到电缆,以及阳螺纹部分,螺旋配合到阴螺纹部分 从而将阴连接器,阳连接器和屋顶面板彼此紧固。 螺栓可以安装在阳连接器和阴连接器之间以允许它们之间的电连接。

    IDENTIFICATION OF BITTER LIGANDS THAT SPECIFICALLY ACTIVATE HUMAN T2R RECEPTORS AND RELATED ASSAYS FOR IDENTIFYING HUMAN BITTER TASTE MODULATORS
    28.
    发明申请
    IDENTIFICATION OF BITTER LIGANDS THAT SPECIFICALLY ACTIVATE HUMAN T2R RECEPTORS AND RELATED ASSAYS FOR IDENTIFYING HUMAN BITTER TASTE MODULATORS 有权
    识别特异性激活人类T2R受体的双键配体和用于鉴定人类叮咬调味剂的相关测定

    公开(公告)号:US20080038739A1

    公开(公告)日:2008-02-14

    申请号:US11766974

    申请日:2007-06-22

    IPC分类号: G01N33/53 C12Q1/02 C12Q1/68

    摘要: The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds. Also, the invention relates to the discovery of specific hT2R9 alleles and their disparate activity in functional assays with the same biter ligands. The invention further relates to the use of these T2R receptors in assays for identifying ligands that modulate the activation of these taste receptors by specific bitter ligands and related compounds. These compounds may be used as additives and/or removed from foods, beverages, cosmetics and medicinals in order to modify (block) T2R-associated bitter taste. Also T2R ligands may be used as therapeutics to treat and modulate T2R associated gastrointestinal and metabolic functions as well as treat gastrointestinal and metabolic diseases such as eating disorders, food sensing, food absorption, obesity, diabetes, Crohn's disease, celiac disease, et al.

    摘要翻译: 本发明涉及T2R味觉受体家族中的特定人味受体对特定苦味化合物的反应的发现。 此外,本发明还涉及特异性hT2R9等位基因的发现及其在具有相同配体配体的功能测定中的不同活性。 本发明还涉及这些T2R受体在用于鉴定通过特定的苦配体和相关化合物调节这些味觉受体的活化的配体的测定中的用途。 这些化合物可以用作添加剂和/或从食品,饮料,化妆品和药物中去除,以便改变(阻断)T2R相关的苦味。 也可以使用T2R配体作为治疗和调节T2R相关胃肠和代谢功能以及治疗胃肠道和代谢疾病如饮食失调,食物感觉,食物吸收,肥胖,糖尿病,克罗恩病,乳糜泻等的治疗剂。

    User-supported multi-language online dictionary
    30.
    发明申请
    User-supported multi-language online dictionary 审中-公开
    用户支持的多语言在线词典

    公开(公告)号:US20070219782A1

    公开(公告)日:2007-09-20

    申请号:US11374941

    申请日:2006-03-14

    申请人: Qing Li

    发明人: Qing Li

    IPC分类号: G06F17/21

    CPC分类号: G06F17/2735 G06F17/24

    摘要: This invention describes an electronic dictionary that is built and maintained by the user community. It is a single source to translate any word from any language into any other language. The dictionary resides with an online server. User with online connection specifies his/her native language and looks up any correct word, misspelled word, acronym, or phrase of any foreign language. The definitions and related information are also supplied by the user community. A user can also place advertisement. He/she can associate the advertisement with the entries in the dictionary. While the dictionary content is user maintained, the administrator has the full control.

    摘要翻译: 本发明描述了由用户社区构建和维护的电子词典。 将任何语言的任何单词翻译成任何其他语言是一个单一的来源。 该字典驻留有一个在线服务器。 具有在线连接的用户指定他/她的母语,并查找任何正确的词,拼写错误的单词,首字母缩略词或任何外语的短语。 定义和相关信息也由用户社区提供。 用户也可以放置广告。 他/她可以将广告与字典中的条目相关联。 当用户维护字典内容时,管理员具有完全的控制权。