公开(公告)号：US06568439B1

公开(公告)日：2003-05-27

申请号：US10009892

申请日：2001-10-22

Applicant: Naomi Se ,  Takehiko Yuki ,  Ryoji Fujii

Inventor： Naomi Se ,  Takehiko Yuki ,  Ryoji Fujii

IPC: B65B104

CPC classification number: B65D51/002 ,  A61J1/1406 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/1487 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2086 ,  A61J1/2089 ,  A61J1/2096

Abstract: A container cap or a liquid communication adapter attachable to a container mouth having a conventional rubber-like stopper. A container cap includes at least one disk-like valve provided with an insertion hole in a central portion thereof, and a cover for restraining the valve by covering at least an upper periphery of the valve. A lower periphery on a back surface of the valve is supported by a seating portion of a container mouth or a seating portion of a joint that is supported by the container mouth, and the container cap has an anchor for anchoring an insertion member to the cap by using a peripheral edge forming a fitting hole in the cover, while inserting the insertion member into the insertion hole.

Abstract translation: 容器盖或可连接到具有常规橡胶状塞子的容器口部的液体连通适配器。 容器盖包括在其中心部分设置有插入孔的至少一个盘状阀，以及用于通过覆盖阀的至少上部周边来限制阀的盖。 阀的后表面上的下周边由容器口的座部或由容器口支撑的接头的座部支撑，并且容器帽具有用于将插入构件固定到帽的锚固件 通过在将插入构件插入到插入孔中的同时使用在盖中形成嵌合孔的周缘。

公开(公告)号：US20030069538A1

公开(公告)日：2003-04-10

申请号：US10231151

申请日：2002-08-30

Inventor： Thomas Pfeifer ,  Dietmar Palm ,  Michael Becker ,  Michael Seipp ,  Rainer Wabnegg

IPC: A61M037/00

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055

Abstract: The invention relates to an apparatus for combining under sterile conditions a liquid component held in a first container and a solid or liquid component held in a second container. Two variants are proposed which ensure safe and complete transfer of the component situated in the first container into the second container. In one variant, two hollow bodies for receiving the two containers are provided, the two hollow bodies (2, 4) being inserted one within the other and being able to slide relative to one another in a guided manner in the longitudinal direction, and a cannula holder (3) which forms a pot-shaped structural unit (29) with the first hollow body is provided with at least one cannula. Instead of such a fundamentally two-piece form, in the context of the other variant, a fundamentally three-piece form is proposed, in which the cannula holder and the first hollow body are separate components, and in which the cannula holder is made pot-shaped (FIG. 1).

Abstract translation: 本发明涉及一种用于在无菌条件下组合保持在第一容器中的液体组分和固定在第二容器中的固体或液体组分的装置。 提出了两种变型，其确保将位于第一容器中的部件安全地和完全地转移到第二容器中。 在一个变型中，提供了两个用于容纳两个容器的中空体，两个空心体（2,4）一个插入另一个中并且能够在纵向上以导向的方式相对于彼此滑动，并且 与第一中空体形成盆形结构单元（29）的套管保持器（3）设置有至少一个插管。 代替这种基本上两片式的形式，在另一变型的上下文中，提出了一种基本上三件式的形式，其中套管保持器和第一中空体是分开的部件，并且其中套管保持器被制成锅 （图1）。

公开(公告)号：US06544246B1

公开(公告)日：2003-04-08

申请号：US09668815

申请日：2000-09-23

Applicant: John J. Niedospial, Jr.

Inventor： John J. Niedospial, Jr.

IPC: A61B1900

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/1468 ,  A61J1/201 ,  A61J1/2044 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/2089 ,  B65D47/2031

Abstract: A vial access adapter for withdrawal of a medical fluid contained in a vial which includes a vial access adapter body having a circular top wall with a plurality of vent holes, a circular second wall spaced from the top wall, and a cylindrical side wall which walls define a chamber for holding an anti-bacterial filter. A first spike centrally located in the vial access adapter body extends through the top wall, chamber, and bottom wall, with one end extending above the top wall terminating in a threaded luer connector, while the other end terminates in a sharp point. A flow channel extends through the first spike designed for withdrawal of the medical fluid from the vial. A second spike positioned parallel to the first spike extends from the second wall, one end of which extends into the chamber, and the other end terminates in a sharp point. A flow channel extends through the second spike designed for air flow from the chamber into the vial. An elastomeric membrane positioned within the threaded luer connector seals the opening in the vial access adapter. Preferably the elastomeric membrane is of M-shaped configuration capable of flexing under pressure and of re-sealing itself after being pierced by a luer connector or a syringe equipped with a luer connector.

Abstract translation: 用于取出容纳在小瓶中的医用流体的小瓶接入适配器，其包括具有多个通气孔的圆形顶壁的小瓶接入适配器主体，与顶壁间隔开的圆形第二壁，以及圆柱形侧壁， 定义一个用于容纳抗菌过滤器的室。 中心位于小瓶接入适配器主体中的第一个尖峰延伸穿过顶壁，室和底壁，一端延伸到顶壁上方终止于螺纹鲁尔连接器，而另一端终止于尖锐点。 流动通道延伸穿过设计用于从小瓶中取出医用流体的第一尖峰。 平行于第一尖钉定位的第二尖峰从第二壁延伸，其一端延伸到腔室中，另一端终止于尖锐点。 流动通道延伸穿过设计用于从腔室进入小瓶的气流的第二尖峰。 定位在螺纹鲁尔连接器内的弹性体膜密封小瓶接入适配器中的开口。 优选地，弹性体膜是M形构造，其能够在被鲁尔连接器或装有鲁尔连接器的注射器刺穿之后能够在压力下弯曲并且自身重新密封。

公开(公告)号：US06524278B1

公开(公告)日：2003-02-25

申请号：US09563268

申请日：2000-05-03

Applicant: John Campbell ,  John Targell

Inventor： John Campbell ,  John Targell

IPC: A61M532

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2086 ,  A61M5/1782 ,  A61M5/3145 ,  A61M5/32 ,  A61M5/3202 ,  A61M5/3234 ,  A61M5/508 ,  A61M2005/3118 ,  A61M2005/3128 ,  A61M2005/3201 ,  A61M2039/042

Abstract: A sheath for sheathing the needle of a hypodermic syringe and penetrating the rubber cap of a vial or the like, the sheath having apertures therein to allow the ingress of liquid into a zone thereof with which the needle communicates so that the liquid drawn through the needle during filling of the syringe first enters that zone before entering the needle. The sheath is further provided with a filter element and/or a needle-wiping element.

Abstract translation: 用于护套皮下注射器的针并穿透小瓶等的橡胶帽的护套，护套中具有孔，以允许液体进入其与针连通的区域，使得通过针抽出的液体 在注射器的填充期间，首先在进入针之前进入该区域。 护套还设置有过滤元件和/或针擦拭元件。

公开(公告)号：US20020193777A1

公开(公告)日：2002-12-19

申请号：US10149397

申请日：2002-06-11

Inventor： Antoine Aneas

IPC: A61B019/00

CPC classification number: A61J1/2096 ,  A61J1/1412 ,  A61J1/201 ,  A61J1/2037 ,  A61J1/2075 ,  A61J1/2082

Abstract: This device comprises a base (10) adapted to be mounted on the recipient (2) and comprising a sleeve (11) forming an internal bore (A), and a piston (20) adapted to slide in the bore (A), between a first position disengaged with respect to a stopper (5) of the recipient (2) and a so-called transfer position in which a hollow needle (22) borne by or constituting the piston (20), traverses the stopper (5). The piston is equipped with a valve (V) for controlling the flow of a fluid from or towards the internal volume of the recipient (2), this valve (V) being integrated in a part (26d) of the piston provided for connection of the container (3) to the needle (22).

Abstract translation: 该装置包括适于安装在接收器（2）上并包括形成内孔（A）的套筒（11）和适于在孔（A）中滑动）的活塞（20）的基座（10） 相对于接收器（2）的止动件（5）脱离的第一位置和由活塞（20）承载或构成活塞（20）的中空针（22）穿过止动件（5）的所谓的转移位置。 该活塞配备有用于控制流体从容器（2）的内部容积流出的流体（V）的阀（V），该阀（V）集成在活塞的一部分（26d）中， 所述容器（3）到所述针（22）。

公开(公告)号：US20020189705A1

公开(公告)日：2002-12-19

申请号：US10084014

申请日：2002-02-25

Inventor： Bruno Reihl ,  Michel Hirsiger ,  Bruno Boos ,  Hanspeter Stoller ,  Edgar Hommann ,  Paolo Pollak ,  Peter Latscha ,  Sandra Soniec ,  Andreas Eberhart

IPC: B65B001/04

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2065

Abstract: A device for transferring a fluid product from one container to another including a hollow needle suitable for piercing a membrane and having a first, front opening, the needle being connectable to one of the containers via a first, rear hollow needle opening so that the fluid product can be conveyed into or out of the container through the hollow needle and hollow needle openings, the needle having a second, rear opening which forms a fluid connection between the another container and a pressure compensation device or the environment while the fluid is being transferred.

Abstract translation: 一种用于将流体产品从一个容器传递到另一个容器的装置，包括适于穿透膜的中空针头并具有第一前开口，所述针可以经由第一后空心针开口连接到容器之一，使得流体 产品可以通过中空针和中空针孔进入或离开容器，针具有第二后开口，其在流体被转移时在另一容器和压力补偿装置之间形成流体连接或环境 。

公开(公告)号：US20020128612A1

公开(公告)日：2002-09-12

申请号：US09812866

申请日：2001-03-21

Applicant: FRESENIUS KABI, AB

Inventor： Gunnar Andersson ,  Bert Petterson

IPC: A61M001/00 ,  A61M005/00

CPC classification number: B65D47/24 ,  A61J1/1425 ,  A61J1/1468 ,  A61J1/1481 ,  A61J1/1487 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2096 ,  Y10S604/905

Abstract: A device for storing and administering a medical fluid comprising a sealed flexible formed container with an opening part in its front end in which an insert is positioned. Over the insert, the container extends into a removable sealing cap. After removal of the sealing cap an injection means is attached to the insert and fluid administration through the insert is admitted in one direction by squeezing the container.

Abstract translation: 一种用于储存和施用医用流体的装置，包括密封的柔性成形容器，其前端具有开口部分，插入件位于该容器的前端。 在插入物上，容器延伸到可移除的密封盖中。 在移除密封帽之后，将注入装置附接到插入件，并且通过挤压容器通过插入件的流体施加沿一个方向进入。

公开(公告)号：US20020127150A1

公开(公告)日：2002-09-12

申请号：US09801504

申请日：2001-03-07

Inventor： John T. Sasso

IPC: B01L003/00

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2055

Abstract: An adapter for mounting on drug vial of various sizes to provide needleless access to the interior of each vial regardless of its size. The adapter includes sharpened cannula surrounded by peripheral sidewall. The peripheral sidewall includes an upper portion and a lower skirt flaring outward from the upper portion and terminates in a peripheral free edge extending beyond the sharpened end of the cannula to protect users from an accidental needle-stick. The sidewall includes plural equidistantly spaced projections extending radially inward to form a ledge also has slits extending upward from the peripheral edge of the skirt to enable portions of the sidewall including the projections to flex outward. By so doing the cap of the vial is enabled to pass between the projections and then return to a position wherein the ledge has inside diameter just slightly less than the outside diameter of the rim of the cap to releasably secure the adapter to the vial with the cannula piercing through the septum of the cap.

Abstract translation: 用于安装在各种尺寸的药瓶上的适配器，无论其尺寸如何，都能无缝地进入每个小瓶的内部。 适配器包括由周边侧壁包围的尖锐插管。 周边侧壁包括从上部向外延伸的上部部分和下部裙部，并且终止于延伸超出插管的尖端的周边自由边缘，以保护使用者免受意外的针刺。 侧壁包括多个等距间隔开的突出部，其径向向内延伸以形成凸缘，还具有从裙部的周边边缘向上延伸的狭缝，以使得包括突起的侧壁部分向外弯曲。 通过这样做，小瓶的盖能够在突起之间通过，然后返回到其中突出部的内径略小于盖的边缘的外径的位置，以将适配器可释放地固定到小瓶上， 套管穿过帽的隔膜。

公开(公告)号：US20020095121A1

公开(公告)日：2002-07-18

申请号：US10011262

申请日：2001-11-07

Inventor： Paul H. Norton ,  John R. Wolfe

IPC: A61M005/00

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2065

Abstract: A syringe safety device coupling between a sealed vial and a syringe and includes a tubular connector having a first axial end non-releasably receiving the vial and a second, opposing axial end releasably receiving a syringe without needle. The tubular connector encloses a sliding joint having opposing open axial ends and a passageway between the ends. A first sliding joint end is adapted to engage an enlarged, blunt mounting end of a syringe needle. A second sliding joint axial end is configured to releasably engage a releasable needle receiver on the end of the syringe without needle. The syringe is releasably removable from the sliding joint after fluid coupling with the vial through the sliding joint, without removal of the needle or the sliding joint from the connector, which captures the needle with the sliding joint in the connector. The first end of a preferred joint includes a receiver, adapted to releasably receive a conventional removable syringe needle, and a mount, adapted to releasably receive a conventional releasable needle receiver of a conventional syringe.

Abstract translation: 一种注射器安全装置，其联接在密封的小瓶和注射器之间，并且包括管状连接器，其具有不可释放地接收小瓶的第一轴向端部和可释放地接收无针的注射器的第二相对轴向端。 管状连接器包围具有相对的开放轴向端部和端部之间的通道的滑动接头。 第一滑动关节端适于接合注射器针头的扩大的，钝的安装端。 第二滑动关节轴向端部构造成可释放地接合注射器的端部上的可释放的针接收器，而无需针头。 在与小瓶通过滑动接头流体联接之后，注射器可从该滑动接头可释放地移除，而不会从连接器中移除针头或滑动接头，该连接器用连接器中的滑动接头捕获针头。 优选关节的第一端包括适于可释放地接收常规可移除注射器针的接收器和适于可释放地接收常规注射器的常规可释放针式接收器的安装件。

公开(公告)号：US20020087141A1

公开(公告)日：2002-07-04

申请号：US09754709

申请日：2001-01-03

Inventor： Freddy Zinger ,  Igor Denenburg

IPC: A61B019/00 ,  A61M005/32

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2037 ,  A61J1/2055 ,  A61J1/2096 ,  A61M2207/00 ,  B65D81/3211

Abstract: A fluid transfer and mixing device for use in the aseptic intermixing of a powder component with a fluid component. The device is of a simple, compact construction that includes a first adapter that can be easily connected to a container containing the powder component and a second adapter that can be removably interconnected with the first adapter and can also be readily connected to a container containing a fluid such as a diluent so as to permit aseptic intermixing of the diluent with the powder. In use a conventional needleless syringe can be easily connected to the first adapter so that the mixture of the powder and diluent can be aseptically aspirated from the first container for subsequent delivery to the patient.

Abstract translation: 一种流体转移和混合装置，用于将粉末组分与流体组分无菌混合。 该装置是简单紧凑的结构，其包括可容易地连接到容纳粉末组件的容器的第一适配器和可与第一适配器可拆卸地互连的第二适配器，并且还可以容易地连接到容纳 流体如稀释剂，以允许稀释剂与粉末的无菌混合。 在使用中，传统的无针注射器可以容易地连接到第一适配器，使得粉末和稀释剂的混合物可以从第一容器无菌吸入，以便随后输送给患者。