Abstract:
The present invention relates to 2-indolinone derivatives which are capable of inhibiting protein kinases and histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal protein kinase activities or abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.
Abstract:
A multi-user multi-input multi-output (MIMO) method for transmitting signal with a includes: performing a Tomlinson-Harashima pre-coding (THP) on raw data; decomposing a channel matrix to a product of a block triangular matrix and a unitary matrix, and generating a signal to be transmitted by performing a forward filtering on the THP coded data by using the unitary matrix. A multi-user MIMO apparatus for transmitting signal includes an interference pre-eliminating unit, a modulo unit, a forward filtering unit, and a channel matrix decomposing unit. A multi-user MIMO communication system is further provided.
Abstract:
A method of optical fabrication comprises coating a substrate with a photocuring material, controlling the application of light to the photocuring material so as to control the intensity and pattern of the light both in-plane and out of plane, and developing the photocuring material.
Abstract:
A user equipment includes an estimator. The estimator is configured to select a first estimate of a signal-to-noise (SNR) ratio, calculate a first amplitude and first noise variance, calculate a second amplitude and a second noise variance, calculate a second SNR, calculate a resolution value, adjust the first SNR, and perform estimation iterations until the resolution value is equal to a predetermined value.
Abstract:
An adaptive equalizer including an equalizer filter and a tap coefficients generator used to process a sample data stream derived from a plurality of received signals is disclosed. The tap coefficients generator includes an equalizer tap update unit, a vector norm square estimator, an active taps mask generator, a switch and a pilot amplitude reference unit used to minimize the dynamic range of the equalizer filter. A dynamic mask vector is used to mask active taps generated by the equalizer tap update unit when an unmasked signal output by the equalizer filter is selected by the switch to generate an error signal fed to the equalizer tap update unit. A fixed mask vector is used to mask active taps generated by the equalizer tap update unit when a masked signal output by the equalizer filter is used to generate the error signal.
Abstract:
Provided herein are isolated compounds of formula 1: processes for their preparation and isolation, as well as pharmaceutical compositions which comprise these therapeutic agents, and methods of use therefore the treatment and/or control of conditions associated with or mediated by effects of histone deacetylase.
Abstract:
In a method and apparatus for accelerating MR temperature imaging used in MR-monitored high intensity focused ultrasound (HIFU) therapy, temperature changes are determined at the focus of the ultrasound during MR temperature imaging; determining the ideal acceleration rate needed for data sampling according to the temperature changes at said focus is determined, the variable-density (VD) data sampling in k-space is adjusted according to the determined ideal acceleration rate, and the data obtained from sampling are reconstructed to form an image. The capability of accelerating MR temperature imaging with both good temporal resolution and good spatial resolution is improved by determining the acceleration rate according to temperature changes at the ultrasound focus and by adjusting the VD data sampling of k-space and thereby the benefits of good flexibility, feasibility and stability are achieved.
Abstract:
Data estimation is performed in a wireless communication system using both oversampling and multiple reception antennas. A receive vector is produced for each antenna at a sampling interval which is a multiple of the chip rate of the received signal. A channel response matrix is produced for each antenna at a preferred multiple of the sampling rate. Each receive vector is processed using a sliding window based approach, where a plurality of successive windows are processed. For each window, a combined circulant channel response matrix is produced using the channel response matrices. Using the combined circulant channel response matrix and a combined received vector comprising each received vector in a discrete Fourier transform based approach to estimate a data vector corresponding to that window; and combining the data vector estimated in each window to form a combined data vector.