2-INDOLINONE DERIVATIVES AS MULTI-TARGET PROTEIN KINASE INHIBITORS AND HISTONE DEACETYLASE INHIBITORS
    351.
    发明申请
    2-INDOLINONE DERIVATIVES AS MULTI-TARGET PROTEIN KINASE INHIBITORS AND HISTONE DEACETYLASE INHIBITORS 有权
    2-INDOLINONE衍生物作为多目标蛋白激酶抑制剂和组胺脱乙酰酶抑制剂

    公开(公告)号:US20090298886A1

    公开(公告)日:2009-12-03

    申请号:US12463107

    申请日:2009-05-08

    CPC classification number: C07D401/14

    Abstract: The present invention relates to 2-indolinone derivatives which are capable of inhibiting protein kinases and histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal protein kinase activities or abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.

    Abstract translation: 本发明涉及能够抑制蛋白激酶和组蛋白脱乙酰酶的2-二氢吲哚酮衍生物。 因此,本发明的化合物可用于治疗与异常蛋白激酶活性或异常组蛋白脱乙酰酶活性相关的疾病。 还公开了包含这些化合物的药物组合物,利用包含这些化合物的药物组合物治疗疾病的方法,以及制备这些化合物的方法。

    MULTI-USER MIMO METHOD, APPARATUS AND COMMUNICATION SYSTEM FOR TRANSMITTING SIGNAL
    352.
    发明申请
    MULTI-USER MIMO METHOD, APPARATUS AND COMMUNICATION SYSTEM FOR TRANSMITTING SIGNAL 有权
    多用户MIMO方法,发送信号的装置和通信系统

    公开(公告)号:US20090290656A1

    公开(公告)日:2009-11-26

    申请号:US12510632

    申请日:2009-07-28

    CPC classification number: H04B7/0443 H04B7/0465

    Abstract: A multi-user multi-input multi-output (MIMO) method for transmitting signal with a includes: performing a Tomlinson-Harashima pre-coding (THP) on raw data; decomposing a channel matrix to a product of a block triangular matrix and a unitary matrix, and generating a signal to be transmitted by performing a forward filtering on the THP coded data by using the unitary matrix. A multi-user MIMO apparatus for transmitting signal includes an interference pre-eliminating unit, a modulo unit, a forward filtering unit, and a channel matrix decomposing unit. A multi-user MIMO communication system is further provided.

    Abstract translation: 一种用于发送信号的多用户多输入多输出(MIMO)方法,包括:对原始数据执行Tomlinson-Harashima预编码(THP); 将信道矩阵分解为块三角矩阵和酉矩阵的乘积,并且通过使用酉矩阵对THP编码数据执行正向滤波来生成要发送的信号。 用于发送信号的多用户MIMO装置包括干扰预消除单元,模单元,正向滤波单元和信道矩阵分解单元。 还提供了一种多用户MIMO通信系统。

    Low bias estimation of small signal-to-noise ratio
    354.
    发明授权
    Low bias estimation of small signal-to-noise ratio 失效
    小信噪比的低偏估计

    公开(公告)号:US07590172B2

    公开(公告)日:2009-09-15

    申请号:US12060541

    申请日:2008-04-01

    CPC classification number: H04L1/20 H04B17/336

    Abstract: A user equipment includes an estimator. The estimator is configured to select a first estimate of a signal-to-noise (SNR) ratio, calculate a first amplitude and first noise variance, calculate a second amplitude and a second noise variance, calculate a second SNR, calculate a resolution value, adjust the first SNR, and perform estimation iterations until the resolution value is equal to a predetermined value.

    Abstract translation: 用户设备包括估计器。 估计器被配置为选择信噪比(SNR)比率的第一估计,计算第一幅度和第一噪声方差,计算第二幅度和第二噪声方差,计算第二SNR,计算分辨率值, 调整第一SNR,并执行估计迭代,直到分辨率值等于预定值。

    Pen
    358.
    外观设计
    Pen 有权

    公开(公告)号:USD590878S1

    公开(公告)日:2009-04-21

    申请号:US29302810

    申请日:2008-01-24

    Applicant: Bin Li

    Designer: Bin Li

    Method and apparatus for accelerating magnetic resonance temperature imaging
    359.
    发明授权
    Method and apparatus for accelerating magnetic resonance temperature imaging 失效
    用于加速磁共振温度成像的方法和装置

    公开(公告)号:US07521930B2

    公开(公告)日:2009-04-21

    申请号:US12056607

    申请日:2008-03-27

    CPC classification number: G01R33/4804 G01K7/38 G01K2213/00 G01R33/4814

    Abstract: In a method and apparatus for accelerating MR temperature imaging used in MR-monitored high intensity focused ultrasound (HIFU) therapy, temperature changes are determined at the focus of the ultrasound during MR temperature imaging; determining the ideal acceleration rate needed for data sampling according to the temperature changes at said focus is determined, the variable-density (VD) data sampling in k-space is adjusted according to the determined ideal acceleration rate, and the data obtained from sampling are reconstructed to form an image. The capability of accelerating MR temperature imaging with both good temporal resolution and good spatial resolution is improved by determining the acceleration rate according to temperature changes at the ultrasound focus and by adjusting the VD data sampling of k-space and thereby the benefits of good flexibility, feasibility and stability are achieved.

    Abstract translation: 在用于MR监测的高强度聚焦超声(HIFU)治疗中用于加速MR温度成像的方法和装置中,在MR温度成像期间在超声的焦点处确定温度变化; 确定根据所述焦点处的温度变化进行数据采样所需的理想加速度,根据确定的理想加速度调整k空间中的可变密度(VD)数据采样,并且从采样得到的数据为 重建形成图像。 通过根据超声聚焦温度变化确定加速度,并通过调整k-空间的VD数据采样,从而提高良好的灵活性的好处,提高了具有良好的时间分辨率和良好的空间分辨率的MR温度成像加速能力, 实现可行性和稳定性。

    REDUCED COMPLEXITY SLIDING WINDOW BASED EQUALIZER
    360.
    发明申请
    REDUCED COMPLEXITY SLIDING WINDOW BASED EQUALIZER 失效
    降低复杂度滑动窗口均衡器

    公开(公告)号:US20080298523A1

    公开(公告)日:2008-12-04

    申请号:US12191702

    申请日:2008-08-14

    Abstract: Data estimation is performed in a wireless communication system using both oversampling and multiple reception antennas. A receive vector is produced for each antenna at a sampling interval which is a multiple of the chip rate of the received signal. A channel response matrix is produced for each antenna at a preferred multiple of the sampling rate. Each receive vector is processed using a sliding window based approach, where a plurality of successive windows are processed. For each window, a combined circulant channel response matrix is produced using the channel response matrices. Using the combined circulant channel response matrix and a combined received vector comprising each received vector in a discrete Fourier transform based approach to estimate a data vector corresponding to that window; and combining the data vector estimated in each window to form a combined data vector.

    Abstract translation: 在使用过采样和多个接收天线的无线通信系统中执行数据估计。 以每个天线的采样间隔产生接收矢量,该采样间隔是接收信号的码片速率的倍数。 以采样率的优选倍数为每个天线产生信道响应矩阵。 使用基于滑动窗口的方法处理每个接收向量,其中处理多个连续的窗口。 对于每个窗口,使用信道响应矩阵来产生组合循环信道响应矩阵。 使用组合的循环信道响应矩阵和包括基于离散傅立叶变换的方法中的每个接收向量的组合接收向量来估计对应于该窗口的数据矢量; 并组合在每个窗口中估计的数据矢量以形成组合的数据向量。

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