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66 条记录 (耗时 0.014 秒)

    Pharmaceutical compositions containing 1,1-azo bis-(1h-imidazo(1,2-a)pyridinium)dibromide compounds and the use thereof
    34.
    发明授权
    Pharmaceutical compositions containing 1,1-azo bis-(1h-imidazo(1,2-a)pyridinium)dibromide compounds and the use thereof 失效
    含有1,1-AZO BIS-（1H-IMIDAZO（1,2-A）PYRIDINIUM）二溴化碳化合物的药物组合物及其用途

    公开(公告)号：US3849557A

    公开(公告)日：1974-11-19

    申请号：US31226172

    申请日：1972-12-05

    申请人： ALLEN & HANBURYS LTD

    发明人： JACK D ,  GLOVER E

    IPC分类号： C07D235/22 ,  C07D519/00 ,  A61K27/00

    CPC分类号： C07D235/22 ,  Y10S514/906

    摘要： 1. AN INJECTABLE COMPOSITION IN DOSAGE UNIT FORM COMPRISING AS ACTIVE INGREDIENT A COMPOUND OF THE FORMULA:

    1-R4,2-R3,3-(1-R4,2-R3,4-R1,5-R2-IMIDAZOL-3-YLIUM-N=N-),

    4-R1,5-R2-IMIDAZOLIUM 2X(-)

    WHEREIN: R1 AND R2, WHICH ARE THE SAME OR DIFFERENT, ARE EACH HYDROGEN, LOWER ALKYL, HALOGEN, PHENYL, PHENYL SUBSTITUTED BY HALOGEN, PHENYL SUBSTITUTED BY HYDROXY, PHENYL SUBSTITUTED BY LOWER ALKOXY, PHENYL SUBSTITUTED BY TRIFLUOROMETHYL, PHENYL SUBSTITUTED BY NITRO; OR TOGETHER WITH THE ADJACENT CARBON ATOMS TO WHICH THEY ARE ATTACHED FORM PHENYL; R3 AND R4, WHICH ARE THE SAME OR DIFFERENT, ARE EACH LOWER ALKYL OR PHENYL, OR TOGETHER WITH THE ADJACENT NITROGEN ATOM FORM PYRIDINIUM OR TETRAHYDROPYRIDINIUM; AND X IS A PHYSIOLOGICALLY ACCEPTABLE ANION, IN ASSOCIATION WITH A PHARMACEUTICALLY ACCEPTABLE CARRIER, WHEREIN EACH DOSAGE UNIT CONTAINS FROM 2 TO 100 MGS. OF ACTIVE INGREDIENT.

    Tetrazolyl chromones
    35.
    发明授权
    Tetrazolyl chromones 失效
    四氯化铬

    公开(公告)号：US3839339A

    公开(公告)日：1974-10-01

    申请号：US10858171

    申请日：1971-01-21

    申请人： ALLEN & HANBURYS LTD

    发明人： ELLIS G ,  SHAW D

    IPC分类号： A61K31/00 ,  C07D311/24 ,  C07D311/92 ,  C07D99/04

    CPC分类号： A61K31/00 ,  C07D311/24 ,  C07D311/92

    摘要： The invention provides compounds of the general formula I:

    (in which R1, R2 and R3, which may be the same or different, represent a hydrogen atom, an alkyl group containing 1-6 carbon atoms, a nitro, amino, alkyl-substituted amino, hydroxy, carboxylic, alkoxy, aryloxy or heterocyclic group, or a halogen atom, and in which the alkoxy group may be substituted by a hydroxy or alkoxy carbonyl group; and pharmaceutically acceptable non-toxic salts threof including esters of those compounds in which the groups R1, R2 or R3 represents a carboxylic group. Pharmaceutical compositions containing these compounds are also provided as well as methods for production thereof.

    摘要翻译： 本发明提供了通式I的化合物：

    Phenylaminoethanol derivatives
    36.
    发明授权
    Phenylaminoethanol derivatives 失效
    苯甲酰胺衍生物

    公开(公告)号：US3732300A

    公开(公告)日：1973-05-08

    申请号：US3732300D

    申请日：1971-05-11

    申请人： ALLEN & HANBURYS LTD

    发明人： LUNTS L ,  TOON P

    IPC分类号： C07C229/38 ,  C07C243/38 ,  C07C103/26

    CPC分类号： C07C243/38 ,  C07C229/38

    摘要： ARE DISCLOSED. SOME HAVE STIMULANT ACTION AND SOME HAVE BLOCKING ACTION ON B-ADRENERGIC RECEPTORS. 5-(2-TERT.BUTYLAMINO-HYDROXYETHYL)-SALICYLAMIDE IN PARTICULAR EXERTS A MARKED BLOCKING EFFECT WHILE BEING REMARKABLY NON-TOXIC AND FREE FROM CENTRAL NERVOUS DEPRESSANT ACTIVITY.

    2-X,(R2-N(-R3)-CH(-R1)-CH(-OH)-)PHENOL

    NOVEL 1-PHENYL-2-AMINO ETHANOL DERIVATIVES OF THE FORMULA:

    Phenylaminoethanol derivatives
    37.
    发明授权
    Phenylaminoethanol derivatives 失效
    苯甲酰胺衍生物

    公开(公告)号：US3705233A

    公开(公告)日：1972-12-05

    申请号：US3705233D

    申请日：1971-06-02

    申请人： ALLEN & HANBURYS LTD

    发明人： LUNTS LAWRENCE HENRY CHARLES ,  TOON PAUL

    IPC分类号： C07C229/38 ,  C07C243/38 ,  C07D295/13 ,  A61K27/00

    CPC分类号： C07D295/13 ,  C07C229/38 ,  C07C243/38

    摘要： NOVEL 1-PHENYL-2-AMINOETHANOL DERIVATIVES OF THE FORMULA:

    2-X,(R2-N(-R3)-CH(-R1)-CH(-OH)-)PHENOL

    ARE DISCLOSED, SOME OF WHICH HAVE STIMULANT ACTION AND SOME OF WHICH HAVE BLOCKING ACTION OF B-ADRENERGIC RECEPTORS. IN PARTICULAR PHARMACEUTICAL COMPOSITIONS COMPRISING A COMPOUND SELECTED FROM A1-T-BUTYLAMINOMETHYL-4-HYDROXY-M-XYLENE-A1-A3-DIOL, 4-HYDROXY-A1((P-METHOXY-AMETHYLPHENETHYL)AMINO)-METHYL) - M- XYLENE-A1,A3-DIOL AND PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, IN ASSOCIATION WITH A PHARMACEUTICALLY-ACCEPTABLE CARRIER ARE DISCLOSED, THE COMPOSITION BEING PREFERABLY IN DOSAGE UNIT FORM. ALSO A METHOD OF TREATING A PATIENT SUFFERING FROM BRONCHOSPASM WHICH COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND SPECIFIED.