公开(公告)号：US11766397B2

公开(公告)日：2023-09-26

申请号：US16706677

申请日：2019-12-07

Applicant: ISP INVESTMENTS LLC

Inventor： Michael Koganov

IPC: A61K8/9789 ,  A61Q19/02

CPC classification number: A61K8/9789 ,  A61Q19/02

Abstract: The present invention provides bioactive compositions comprising Ficus serum fraction derived from Ficus cell juice of fresh Ficus leaves and a process of preparing the Ficus serum fraction. The compositions have biological activity capable of reducing skin hyperpigmentation.

公开(公告)号：US20230263712A1

公开(公告)日：2023-08-24

申请号：US18012373

申请日：2021-06-28

Applicant: ISP INVESTMENTS LLC

Inventor： Hani M. FARES ,  Yevgeniy TUROVSKIY ,  Solomon Howard JACOBSON ,  Philip John OTHS ,  Petros GEBRESELASSIE ,  Joseph TORELLA ,  Karen WINKOWSKI

IPC: A61K8/35 ,  A61Q11/00

CPC classification number: A61K8/35 ,  A61Q11/00 ,  A61K2800/524 ,  A61K2800/92 ,  A61K2800/74

Abstract: An oral care antimicrobial composition comprises about 0.1 to about 99.9 wt. % of at least one compound having the structure of




Also disclosed is a process for preparing the composition and methods of use thereof.

公开(公告)号：US20230240953A1

公开(公告)日：2023-08-03

申请号：US18011903

申请日：2021-06-28

Applicant: ISP INVESTMENTS LLC

Inventor： Solomon Howard JACOBSON ,  Yevgenly TUROVSKIY ,  Joseph TORELLA ,  Karen WINKOWSKI

IPC: A61K8/35

CPC classification number: A61K8/35 ,  A61K2800/74 ,  A61K2800/524

Abstract: The present application provides an antimicrobial composition comprising: (a) about 0.01 to about 99.9 wt. % of at least one compound having a structure of formula (I) or formula (II):




wherein R1 is hydrogen, alkyl, alkoxy or hydroxyl; R2 is hydrogen, alkyl or alkoxy; and (b) about 0.1 to about 95% wt. % of one or more antimicrobial compounds not being compounds of formula (I) and formula (II). Also disclosed is a process for preparing the compositions and method of use thereof.

公开(公告)号：US20230015456A1

公开(公告)日：2023-01-19

申请号：US17939193

申请日：2022-09-07

Applicant: ISP INVESTMENTS LLC

Inventor： Corinne COQUET

IPC: A61K8/92 ,  A61K8/9789 ,  A61K8/37 ,  A61K8/66 ,  A61Q19/08 ,  C11B15/00 ,  A61K8/97

Abstract: The invention relates to a method for obtaining the water-insoluble fraction of Carica papaya sap, enriched with Carica papaya lipase, the water-insoluble fraction obtainable by this method, a method for the preparation of an activated fat and/or an activated wax by means of said water-insoluble fraction of the Carica papaya sap, the activated fat and/or the activated wax capable of being obtained by this method, a composition combining said activated fat and/or said activated wax, as well as the cosmetic use of these products.

公开(公告)号：US20220387290A1

公开(公告)日：2022-12-08

申请号：US17613841

申请日：2020-02-18

Applicant: ISP INVESTMENTS LLC

Inventor： Donald I PRETTYPAUL ,  Diane M. KENNEDY ,  Hani M. FARES

IPC: A61K8/81 ,  A61K8/06 ,  A61K8/35 ,  A61K8/365 ,  A61K8/40 ,  A61Q17/04

Abstract: Disclosed herein is a sunscreen composition(s) comprising (i) at least one sunscreen active ingredient(s); (ii) at least one copolymer of vinyl pyrrolidone (VP) and styrene; and (iii) at least one pharmaceutically or cosmetically or dermatologically acceptable excipient. Also disclosed is a method of protecting human skin and animal skin against damages caused by ultra-violet (UV) radiations from the sun rays.

公开(公告)号：US20220030862A1

公开(公告)日：2022-02-03

申请号：US17297628

申请日：2019-12-02

Applicant: ISP INVESTMENTS LLC

Inventor： Meiyan GUO ,  Karen WINKOWSKI ,  Najeeb H. HAKIMI ,  Raman PREMACHANDRAN ,  Xin QU

IPC: A01N43/28 ,  A01N31/14 ,  A01N37/28 ,  A01N31/02

Abstract: Described herein is a synergistic preservative composition used for providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds selected from the group consisting of propanediol, capryl hydroxamic acid, and isopropyl methyl phenol; and (iii) about 0.1 wt. % to 99.0 wt. % of phenoxyethanol, a preservative compound, and wherein, the composition provides synergy having Synergy Index (SI) value of the total composition from about 0.05 to about 1.0. Also described is a process for preparing said synergistic preservative composition and method of using the same.

公开(公告)号：US11224222B2

公开(公告)日：2022-01-18

申请号：US15561222

申请日：2016-03-25

Applicant: ISP Investments LLC

Inventor： Raman Premachandran ,  Kalpa Metha ,  Jyoti Gupta ,  Najeeb H. Hakimi ,  Karen W Winkowski

IPC: A61K8/35 ,  A01N43/16 ,  A61Q19/00 ,  A61K8/49 ,  A01N25/02 ,  A61Q5/02

Abstract: What is described herein is a stable and reduced-yellowing/non-yellowing synergistic preservative composition comprising: (i) about 0.1 wt. % to about 40 wt. % of dehydroacetic acid (DHA); and about 0.1 wt. % to about 99.9 wt. % of at least one aprotic solvent. Also described herein are aqueous and non-aqueous based preservative compositions for various end-user applications, and processes for preparing and using such compositions to reduce yellowing of DHA when added to the end-user applications.

公开(公告)号：US20210347978A1

公开(公告)日：2021-11-11

申请号：US17277686

申请日：2019-09-17

Applicant: ISP INVESTMENTS LLC

Inventor： Thomas DURIG ,  Paul C. GILLETTE ,  Michael A. TALLON

IPC: C08L39/06 ,  C08L31/04 ,  A61K45/06 ,  A61K47/32 ,  A61K47/10

Abstract: A peroxide stable polymer composition comprises a mixture of polyvinylpyrrolidone/vinyl acetate copolymer (PVP/VA) and butylated hydroxy anisole (BHA), an antioxidant. Products or applications comprising said stable polymer composition and a process for the preparation thereof are disclosed in the present application.

公开(公告)号：US11103437B2

公开(公告)日：2021-08-31

申请号：US15749941

申请日：2016-08-03

Applicant: ISP INVESTMENTS LLC

Inventor： Osama M. Musa ,  Ezat Khosravi ,  Peter Andrew King ,  Allwyn Colaco

IPC: A61K8/81 ,  A61Q5/06 ,  A61Q17/04 ,  A61K8/04 ,  C08F8/00

Abstract: The invention provides a personal care composition comprising polymers having the structure: wherein Q, R1, a, b, and c are described herein. The invention further provides hair care compositions comprising the polymers. Particularly, the hair care composition is a hair styling composition that provides hairstyle retention at a relative humidity exceeding about 40 percent. The invention furthermore provides a method of providing hairstyle retention to hair at a relative humidity exceeding about 40 percent, the method comprising applying to hair the hair care composition as described herein.

公开(公告)号：US11021505B2

公开(公告)日：2021-06-01

申请号：US15774754

申请日：2016-11-10

Applicant: ISP INVESTMENTS LLC

Inventor： Elodie Oger ,  Valerie Lequoy ,  Frederique Portolan

IPC: C12N15/10 ,  C07H1/08 ,  A61K8/60 ,  C07H21/02 ,  A61Q19/08 ,  A61K8/9789 ,  A61Q19/00 ,  A61Q17/04 ,  A61K8/9794 ,  A61K8/44

Abstract: The invention relates to an aqueous extract enriched with small RNA having a maximum length of 150 nucleotides, from plant material. The invention relates to an aqueous extract of plant material, enriched with small RNAs having a maximum length of 150 nucleotides, which can be obtained by such a method, as well as to the compositions comprising such an extract and to their cosmetic uses for combating the signs of skin aging and for improving the hydration of the skin.