公开(公告)号：US20220030862A1

公开(公告)日：2022-02-03

申请号：US17297628

申请日：2019-12-02

Applicant: ISP INVESTMENTS LLC

Inventor： Meiyan GUO ,  Karen WINKOWSKI ,  Najeeb H. HAKIMI ,  Raman PREMACHANDRAN ,  Xin QU

IPC: A01N43/28 ,  A01N31/14 ,  A01N37/28 ,  A01N31/02

Abstract: Described herein is a synergistic preservative composition used for providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds selected from the group consisting of propanediol, capryl hydroxamic acid, and isopropyl methyl phenol; and (iii) about 0.1 wt. % to 99.0 wt. % of phenoxyethanol, a preservative compound, and wherein, the composition provides synergy having Synergy Index (SI) value of the total composition from about 0.05 to about 1.0. Also described is a process for preparing said synergistic preservative composition and method of using the same.

公开(公告)号：US20190142002A1

公开(公告)日：2019-05-16

申请号：US16096422

申请日：2017-04-25

Applicant: ISP INVESTMENTS LLC

Inventor： Raman PREMACHANDRAN ,  Najeeb H. HAKIMI ,  Ryan V. BLAZEWICZ ,  Jennifer MUSYOKI ,  Karen WINKOWSKI

IPC: A01N43/36 ,  A01N25/10 ,  C08F226/06

Abstract: An antimicrobial polymer composition comprising: (i) about 0.1 wt. % to about 50 wt. % of efficacy enhancing poly (isobutylene-co-maleic anhydride) polymer functionalized with (a) at least one pseudo cationic agent selected from the group consisting of functionalized and unfunctionalized primary, secondary or tertiary amines, (b) at least one compound selected from functionalized and unfunctionalized C1 to C12 alcohols and (c) at least one hydrophobic moiety selected from functionalized and unfunctionalized C4 to C20 amines; (ii) about 0.1 wt. % to about 50 wt. % of at least one neutralizing agent for enhancing efficacy of said polymer; and (iii) about 0.1 wt. % to about 99.9 wt. % of delivery system comprising at least one solvent. Also disclosed is a process for preparing the antimicrobial compositions and methods of use thereof.

公开(公告)号：US20180092843A1

公开(公告)日：2018-04-05

申请号：US15564916

申请日：2016-03-29

Applicant: ISP Investments LLC

Inventor： Nadia KONATE ,  Raman PREMACHANDRAN ,  Karen WINKOWSKI ,  Andrea WINGENFELD

IPC: A61K9/10 ,  A01N31/04 ,  A01N25/04 ,  A01N25/30 ,  A61K8/02 ,  A61K8/34 ,  A61K8/39 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q19/00 ,  C11B9/00 ,  C11D17/00

CPC classification number: A61K9/10 ,  A01N25/04 ,  A01N25/30 ,  A01N31/04 ,  A61K8/0295 ,  A61K8/34 ,  A61K8/345 ,  A61K8/347 ,  A61K8/39 ,  A61K47/10 ,  A61K47/14 ,  A61K2800/10 ,  A61K2800/524 ,  A61K2800/596 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  C11B9/0061 ,  C11D1/667 ,  C11D1/83 ,  C11D3/2034 ,  C11D3/2044 ,  C11D3/48 ,  C11D3/50 ,  C11D17/0026 ,  Y02A50/473 ,  Y02A50/481 ,  A01N31/02

Abstract: An aqueous multilamellar composition for delivering a hydrophobic substance comprising: (i) about 50 wt. % to about 80 wt. % of phenylethylalcohol and/or phenylpropylalcohol; (ii) a mixture of (a) about 10 wt. % to about 20 wt. % of polyglyceryl-4 laurate/sebacate and (b) about 10 wt. % to about 20 wt. % of polyglyceryl-6 caprylate/caprate; (iii) about 10 wt. % to about 20 wt. % of octane-1,2-diol; (iv) optionally about 10 wt. % to about 20 wt. % of 1,3-propanediol; and (v) about 5.0 wt. % to about 80 wt. % of water. Also described is a method of use and process for preparing the same.

公开(公告)号：US20180092357A1

公开(公告)日：2018-04-05

申请号：US15564987

申请日：2016-04-07

Applicant: ISP Investments LLC

Inventor： Raman PREMACHANDRAN ,  Najeeb H. HAKIMI ,  Kalpa MEHTA ,  Karen WINKOWSKI ,  Jennifer MUSYOKI ,  Jyoti GUPTA

IPC: A01N43/28 ,  A01N31/02 ,  A01N25/22 ,  C11D3/48 ,  C11D7/26 ,  C11D3/20

CPC classification number: A01N43/28 ,  A01N25/22 ,  A01N31/02 ,  A01N2300/00 ,  C02F1/50 ,  C11D3/2093 ,  C11D3/48 ,  C11D7/267 ,  D21H21/36 ,  A01N31/04 ,  A01N31/06 ,  A01N31/08 ,  A01N33/12 ,  A01N35/02 ,  A01N35/04 ,  A01N37/02 ,  A01N37/04 ,  A01N37/10 ,  A01N37/28 ,  A01N37/40 ,  A01N37/52 ,  A01N41/00 ,  A01N47/06

Abstract: What is described herein is a synergistic preservative composition capable of providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds, and wherein, inclusion of each additional organic compound is capable of demonstrating cumulative synergistic effect; and (iii) optionally about 0.1 wt. % to 99.0 wt. % of one or more preservative compounds, and wherein, inclusion of each preservative compound is capable of demonstrating cumulative synergistic effect, wherein the Synergy Index (SI) value of the total composition is from about 0.05 to about 0.95. Also described is a process for preparing said composition and method of use of the same.

公开(公告)号：US20180055048A1

公开(公告)日：2018-03-01

申请号：US15561222

申请日：2016-03-25

Applicant: ISP Investments LLC

Inventor： Raman PREMACHANDRAN ,  Kalpa METHA ,  Jyoti GUPTA ,  Najeeb H. HAKIMI ,  Karen W WINKOWSKI

IPC: A01N43/16 ,  A01N25/02 ,  A61K8/49 ,  A61Q19/00 ,  A61Q5/02

CPC classification number: A01N43/16 ,  A01N25/02 ,  A61K8/35 ,  A61K8/4973 ,  A61K8/498 ,  A61K2800/524 ,  A61Q5/02 ,  A61Q19/00 ,  A01N25/22

Abstract: What is described herein is a stable and reduced-yellowing/non-yellowing synergistic preservative composition comprising: (i) about 0.1 wt. % to about 40 wt. % of dehydroacetic acid (DHA); and about 0.1 wt. % to about 99.9 wt. % of at least one aprotic solvent. Also described herein are aqueous and non-aqueous based preservative compositions for various end-user applications, and processes for preparing and using such compositions to reduce yellowing of DHA when added to the end-user applications.