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    Anti-paravalvular leakage component for a transcatheter valve prosthesis
    31.
    发明授权
    Anti-paravalvular leakage component for a transcatheter valve prosthesis 有权

    公开(公告)号：US10973630B2

    公开(公告)日：2021-04-13

    申请号：US16571456

    申请日：2019-09-16

    Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

    Inventor： Mark Torrianni ,  Eric Richardson ,  Kshitija Garde

    IPC: A61F2/24

    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

    MATERIAL FOR TREATMENT OF A HEART VALVE, IN PARTICULAR A MITRAL VALVE
    32.
    发明申请
    MATERIAL FOR TREATMENT OF A HEART VALVE, IN PARTICULAR A MITRAL VALVE 审中-公开

    公开(公告)号：US20200060826A1

    公开(公告)日：2020-02-27

    申请号：US16666494

    申请日：2019-10-29

    Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

    Inventor： Jacques R. SEGUIN ,  Bruno LECOINTE

    IPC: A61F2/24 ,  A61B17/068

    Abstract: This material comprises an annuloplasty member able to be introduced using a catheter through minimally invasive vascular access, then to be delivered by said catheter and fixed to the valve annulus. According to the invention, it includes at least one catheter comprising at least one guide member able to be deployed from said catheter such that it extends along one portion of the valve annulus of the valve, in the immediate proximity of said valve annulus, and an implant having a helical shape engaged on said guide member, connected, with separation possibility, to actuation means making it possible to cause this implant to move forward while driving it in rotation around its axis; the implant can thus be deployed from the catheter while being simultaneously moved forward and driven in rotation along its axis.

    Heart valve prosthesis and methods of manufacture and use
    33.
    发明授权
    Heart valve prosthesis and methods of manufacture and use 有权

    公开(公告)号：US10478291B2

    公开(公告)日：2019-11-19

    申请号：US15295350

    申请日：2016-10-17

    Applicant: Medtronic CV Luxembourg S.A.R.L.

    Inventor： Than Nguyen ,  Hung Nguyen ,  MyKim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

    IPC: A61F2/24

    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

    Visualization device for use with a tray for loading a medical device
    35.
    发明授权
    Visualization device for use with a tray for loading a medical device 有权
    用于装载医疗装置的托盘的可视化装置

    公开(公告)号：US09211162B2

    公开(公告)日：2015-12-15

    申请号：US13658082

    申请日：2012-10-23

    Applicant: Medtronic CV Luxembourg S.a.r.l.

    Inventor： Dawn Kruetzfeldt ,  Glenn Stante ,  Sameer Upadhyaya

    IPC: B65D83/10 ,  A61B19/00 ,  A61F2/24 ,  A61F2/95

    CPC classification number: A61B19/5212 ,  A61B90/361 ,  A61B2090/3616 ,  A61B2090/3618 ,  A61F2/0095 ,  A61F2/2427 ,  A61F2/2436 ,  A61F2002/9522 ,  B65D77/24 ,  B65D2201/00

    Abstract: A visualization device for use with a loading tray includes a frame comprising a floor, a first side wall extending generally perpendicular from the floor, and a second side wall extending generally perpendicular from the floor and spaced from the first side wall. The visualization device further includes a mirror abutting the floor of the frame. A magnifying glass may also be supported by top edges of the first and second side walls, or by runners coupled to the top edges of the first and second side walls. The visualization device may be slideably disposed in a reservoir of a loading tray.

    Abstract translation: 用于装载托盘的可视化装置包括框架，该框架包括地板，大体上垂直于地板延伸的第一侧壁以及从地板大致垂直延伸并与第一侧壁间隔开的第二侧壁。 可视化装置还包括邻接框架的底板的反射镜。 放大镜也可以由第一和第二侧壁的顶部边缘或由与第一和第二侧壁的顶部边缘相连的流道支撑。 可视化装置可以可滑动地设置在装载盘的贮存器中。

    Anti-paravalvular leakage components for a transcatheter valve prosthesis
    36.
    发明授权
    Anti-paravalvular leakage components for a transcatheter valve prosthesis 有权
    用于经导管瓣膜假体的抗瓣膜泄漏组件

    公开(公告)号：US09132007B2

    公开(公告)日：2015-09-15

    申请号：US13738376

    申请日：2013-01-10

    Applicant: Medtronic CV Luxembourg S.a.r.l.

    Inventor： Ana Menk ,  Scott Mosher

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2439 ,  A61F2/246 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2250/0003 ,  A61F2250/001 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2250/0071

    Abstract: A valve prosthesis includes one or more anti-paravalvular leakage components coupled to a stent. The anti-paravalvular leakage component may encircle the stent and include a radially expandable control ring coupled to an unattached edge of a flexible skirt which extends the unattached skirt edge outwardly away from the stent and against the native heart valve to form an open-ended annular pocket around the stent. The anti-paravalvular leakage component may encircle the perimeter of the stent and include a flexible skirt having opposing edges coupled to the stent to form one or more enclosed compartments around the stent. Each compartment includes a one-way valve which allows for blood flow into the compartment but prevents blood flow out of the compartment. The anti-paravalvular leakage component may be at least one flap that is coupled to an inner surface of the stent and formed of a flexible material moveable by blood flow.

    Abstract translation: 瓣膜假体包括联接到支架的一个或多个抗瓣膜泄漏部件。 抗瓣膜泄漏部件可以环绕支架并且包括联接到柔性裙部的未附接边缘的径向可扩张的控制环，其将未附着的裙边缘向外远离支架并抵靠天然心脏瓣膜，以形成开放式环形 口袋周围支架。 抗瓣膜泄漏部件可以环绕支架的周边，并且包括柔性裙部，其具有联接到支架的相对边缘，以在支架周围形成一个或多个封闭隔室。 每个隔间包括一个单向阀，其允许血液流入隔室，但防止血液流出隔室。 抗瓣膜泄漏部件可以是至少一个翼片，其联接到支架的内表面并且由可由血流移动的柔性材料形成。

    Medical Device Delivery System and Methods of Delivering a Medical Device
    37.
    发明申请
    Medical Device Delivery System and Methods of Delivering a Medical Device 审中-公开
    医疗器械输送系统及医疗器械的提供方法

    公开(公告)号：US20140142688A1

    公开(公告)日：2014-05-22

    申请号：US13681529

    申请日：2012-11-20

    Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

    Inventor： Niall Duffy ,  John Gallagher ,  Gerry McCaffrey ,  Noam Miller ,  Glenn Stante

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2002/9522 ,  A61M29/00

    Abstract: A medical device delivery system can include a dilator including a tip having a taper in a distal direction, a coupler, and a flap that radially protrudes from the tip. The flap can be configured to bend against a body lumen to cover at least a portion of the delivery system when the dilator is tracked through the body lumen. A medical device delivery system can include a dilator including a tip having a lumen and a coupler having a lumen. The coupler can be configured to securely connect to the tip such that the lumen of the tip is aligned with the lumen of the coupler to allow a guide wire to pass therethrough. Methods for loading a medical device into a delivery catheter are also disclosed.

    Abstract translation: 医疗装置输送系统可以包括扩张器，其包括在远端方向具有锥形的尖端，联接器和从尖端径向突出的瓣。 当扩张器通过体腔跟踪时，翼片可构造成相对于体腔折叠以覆盖输送系统的至少一部分。 医疗装置输送系统可以包括包括具有内腔的尖端和具有内腔的联接器的扩张器。 耦合器可以被配置成牢固地连接到尖端，使得尖端的内腔与耦合器的内腔对准以允许导丝通过。 还公开了将医疗装置装载到输送导管中的方法。

    ANTI-PARAVALVULAR LEAKAGE COMPONENT FOR A TRANSCATHETER VALVE PROSTHESIS
    38.
    发明申请
    ANTI-PARAVALVULAR LEAKAGE COMPONENT FOR A TRANSCATHETER VALVE PROSTHESIS 有权

    公开(公告)号：US20250134658A1

    公开(公告)日：2025-05-01

    申请号：US19010897

    申请日：2025-01-06

    Applicant: Medtronic CV Luxembourg S.A.R.L.

    Inventor： Kshitija GARDE ,  Joel RACCHINI ,  Paul ROTHSTEIN ,  Jeffrey SANDSTROM

    IPC: A61F2/24

    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

    Catheter shaft with uniform bending stiffness circumferentially
    39.
    发明授权
    Catheter shaft with uniform bending stiffness circumferentially 有权

    公开(公告)号：US12138400B2

    公开(公告)日：2024-11-12

    申请号：US18487274

    申请日：2023-10-16

    Applicant: MEDTRONIC CV LUXEMBOURG S.A.R.L.

    Inventor： Susheel Deshmukh

    IPC: A61M25/00 ,  A61F2/24 ,  A61F2/95 ,  A61F2/966 ,  A61L29/04 ,  A61M25/16 ,  B29C48/00 ,  B29C48/09 ,  B29L31/00

    Abstract: A catheter shaft includes an inner layer defining an innermost circumferential surface of the catheter shaft and defining a lumen of the catheter shaft, and an outer layer defining an outermost circumferential surface of the catheter shaft. The inner layer is formed by a first polymer having a first durometer and a first melting temperature. The outer layer is formed by alternating first and second segments of the first polymer and a second polymer, respectively, that alternate in a circumferential direction. The second polymer has a second durometer softer than the first durometer and a second melting temperature lower than the first melting temperature. Each segment of the alternating first and second segments extend in an axial direction for substantially an entire length of the catheter shaft. A method of forming the catheter shaft via extrusion is also disclosed.

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