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公开(公告)号：US20120264789A1
公开(公告)日：2012-10-18
申请号：US13497861
申请日：2010-09-24
Applicant: Jagdev Singh Jaryal , Swargam Sathyanarayana , Rajesh Kumar Thaper , Mohan Prasad
Inventor： Jagdev Singh Jaryal , Swargam Sathyanarayana , Rajesh Kumar Thaper , Mohan Prasad
IPC: C07D213/81 , A61P35/00 , A61K31/44
CPC classification number: C07D213/68 , C07D213/81
Abstract: The present invention provides amorphous and crystalline forms of acid addition salts of sorafenib, pharmaceutical compositions comprising them and their use for the treatment of cancer. The present invention also provides processes for the preparation of acid addition salts of sorafenib.
Abstract translation: 本发明提供索拉菲尼的无定形和结晶形式的酸加成盐，包含它们的药物组合物及其用于治疗癌症的用途。 本发明还提供了制备索拉非尼的酸加成盐的方法。
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公开(公告)号：US20110086884A1
公开(公告)日：2011-04-14
申请号：US12973499
申请日：2010-12-20
Applicant: Yatendra KUMAR , Mahavir Singh Khanna , Mohan Prasad
Inventor： Yatendra KUMAR , Mahavir Singh Khanna , Mohan Prasad
IPC: A61K31/4439 , C07D401/12 , A61P1/04
CPC classification number: C07D401/12 , A61K31/4439
Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
Abstract translation: 本发明涉及（S） - 奥美拉唑的结晶钡盐，其为（S）-5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2-吡啶基） - 甲基]亚磺酰基〕-1H 苯并咪唑。 本发明还涉及制备（S） - 奥美拉唑的结晶钡盐的方法和包括如此制备的（S） - 奥美拉唑的结晶钡盐的药物组合物。
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公开(公告)号：US20090171104A1
公开(公告)日：2009-07-02
申请号：US12089245
申请日：2006-05-10
Applicant: Killol Patel , Seema Kanwar , Keshav Deo , Mohan Prasad
Inventor： Killol Patel , Seema Kanwar , Keshav Deo , Mohan Prasad
IPC: C07D305/12
CPC classification number: C07D305/12
Abstract: The present invention provides a process for preparing orlistat (I) by alkanoylating an amino orlistat using formic acid anhydride as an alkanoylating agent to obtain orlistat substantially free of the byproduct, (S)-N-acetylleucine (1S)-1-[[(2S, 3S)-3-hexyl-4-oxo-2-oxetanyl]methyl] dodecyl ester (deformyl-N-acetyl orlistat).
Abstract translation: 本发明提供了通过使用甲酸酐作为烷酰化剂烷基化氨基奥利司他来获得基本上不含副产物的奥利司他的（S）-N-乙酰基亮氨酸（1S）-1 - [[（ 2S，3S）-3-己基-4-氧代-2-氧杂环丁烷基]甲基]十二烷基酯（去甲酰基-N-乙酰基奥利司他）。
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公开(公告)号：US20070244144A1
公开(公告)日：2007-10-18
申请号：US11733594
申请日：2007-04-10
Applicant: Deepak MURPANI , Mohammad RAFEEQ , Praveen RAHEJA , Swargam SATHYANARAYANA , Mohan PRASAD
Inventor： Deepak MURPANI , Mohammad RAFEEQ , Praveen RAHEJA , Swargam SATHYANARAYANA , Mohan PRASAD
IPC: A61K31/473 , C07D221/06
CPC classification number: C07D401/04
Abstract: The present invention relates to an improved process for the preparation of Form 1 of desloratadine essentially free of Form 2. The invention also relates to Form 1 of desloratadine substantially free of Form 2, process for its preparation, pharmaceutical composition comprising it and its method of use for the treatment of allergic reactions in mammals.
Abstract translation: 本发明涉及用于制备基本上不含形式2的地氯雷他定1型的改进方法。本发明还涉及基本上不含形式2的地氯雷他定1型，其制备方法，包含其的药物组合物及其方法 用于治疗哺乳动物过敏反应。
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公开(公告)号：US20060040915A1
公开(公告)日：2006-02-23
申请号：US10513004
申请日：2002-04-26
Applicant: Yatendra Kumar , Mohan Prasad , Ashok Prasad , Shailendra Singh , Neela Kumar
Inventor： Yatendra Kumar , Mohan Prasad , Ashok Prasad , Shailendra Singh , Neela Kumar
IPC: A61K31/545 , C07D501/14
CPC classification number: C07D501/22 , C07D501/00
Abstract: The present invention relates to a process for the preparation of cefdinir on an industrial scale.
Abstract translation: 本发明涉及以工业规模制备头孢地尼的方法。
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Patent Agency Ranking
公开(公告)号：US09315764B1
公开(公告)日：2016-04-19
申请号：US12771725
申请日：2010-04-30
Applicant: Mohan Prasad A. Dasari , Abdullah A. Mahfuz
Inventor： Mohan Prasad A. Dasari , Abdullah A. Mahfuz
CPC classification number: C11B13/02 , A23J7/00 , A23K20/158 , A23K20/26 , C11B1/025 , C11B11/00 , C11B13/00 , C12P7/64 , C12Y301/01004 , C12Y301/01032 , C12Y301/04003 , Y02W30/74
Abstract: The present invention provides methods of processing lipid materials such as soapstock, wet gums and dry gums. Enzymes are utilized to catalyze hydrolysis of the lipids materials to recover fatty acids. Addition of organic acids and/or polyols improved yield of fatty acids and reduced formation of emulsion. Lipid materials can be formulated with other agricultural products as new value-added animal fee products.
Abstract translation: 本发明提供了加工脂质物质如皂片，湿胶和干胶的方法。 酶用于催化脂质物质的水解以回收脂肪酸。 加入有机酸和/或多元醇改善了脂肪酸的产率并减少了乳液的形成。 脂类材料可以与其他农产品配制成新的增值动物费用产品。
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公开(公告)号：US20140357870A1
公开(公告)日：2014-12-04
申请号：US14127680
申请日：2012-06-20
Applicant: Anmol Kumar Ray , Anu Mittal , Nagaraju Gottumukkala , Mahavir Singh Khanna , Rajesh Kumar Thaper , Mohan Prasad , Sudershan Kumar Arora
Inventor： Anmol Kumar Ray , Anu Mittal , Nagaraju Gottumukkala , Mahavir Singh Khanna , Rajesh Kumar Thaper , Mohan Prasad , Sudershan Kumar Arora
IPC: C07D401/12
CPC classification number: C07D401/12
Abstract: The present invention relates to a process for the preparation of dexlansoprazole.xH2O, wherein x is about 0.0 to about 0.1, using dexlansoprazole.xH2O, wherein x is about 2.6 to about 50.
Abstract translation: 本发明涉及使用右兰索拉唑×H 2 O制备右兰索拉唑×H 2 O的方法，其中x为约0.0至约0.1，其中x为约2.6至约50。
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38.发明授权公开(公告)号：US08816072B2
公开(公告)日：2014-08-26
申请号：US13375548
申请日：2010-06-02
Applicant: Deepak Mohanlal Jain , Maneck Khurana , Hiten Sharadchandra Mehta , Abhay Tatiya , Asok Nath , Sanjay Mahadeo Gade , Mohan Prasad , Subhash Dhar
Inventor： Deepak Mohanlal Jain , Maneck Khurana , Hiten Sharadchandra Mehta , Abhay Tatiya , Asok Nath , Sanjay Mahadeo Gade , Mohan Prasad , Subhash Dhar
IPC: C07D413/06
CPC classification number: C07D413/06
Abstract: The present invention provides a process for preparation of crystalline aprepitant having not more than 15% by weight of Form I content which comprises, a) dissolving aprepitant in a suitable solvent to obtain a solution, b) cooling the solution to 10-15° C., c) optionally seeding the solution with aprepitant Form I crystals, d) adding an anti-solvent to the solution, and e) isolating crystalline aprepitant having not more than 15% by weight of Form I content.
Abstract translation: 本发明提供一种制备具有不超过15重量％的形式I含量的结晶阿拉曲百特的方法，其包括：a）将阿瑞消制剂溶解在合适的溶剂中以获得溶液，b）将溶液冷却至10-15℃ c）任选地用溶液形式I晶体接种该溶液，d）向该溶液中加入抗溶剂，和e）分离不超过15重量％的形式I含量的结晶阿拉米特。
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公开(公告)号：US08614329B2
公开(公告)日：2013-12-24
申请号：US13912305
申请日：2013-06-07
Applicant: Jagdev Singh Jaryal , Swargam Sathyanarayana , Rajesh Kumar Thaper , Mohan Prasad
Inventor： Jagdev Singh Jaryal , Swargam Sathyanarayana , Rajesh Kumar Thaper , Mohan Prasad
IPC: A61K31/44 , C07D213/81
CPC classification number: C07D213/68 , C07D213/81
Abstract: The present invention provides amorphous and crystalline forms of acid addition salts of sorafenib, pharmaceutical compositions comprising them, and their use for the treatment of cancer. The present invention also provides processes for the preparation of acid addition salts of sorafenib.
Abstract translation: 本发明提供索拉非尼的酸加成盐的无定形和结晶形式，包含它们的药物组合物及其用于治疗癌症的用途。 本发明还提供了制备索拉非尼的酸加成盐的方法。
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公开(公告)号：US20130274478A1
公开(公告)日：2013-10-17
申请号：US13912305
申请日：2013-06-07
Applicant: Jagdev Singh JARYAL , Swargam SATHYANARAYANA , Rajesh Kumar THAPER , Mohan PRASAD
Inventor： Jagdev Singh JARYAL , Swargam SATHYANARAYANA , Rajesh Kumar THAPER , Mohan PRASAD
IPC: C07D213/68
CPC classification number: C07D213/68 , C07D213/81
Abstract: The present invention provides amorphous and crystalline forms of acid addition salts of sorafenib, pharmaceutical compositions comprising them, and their use for the treatment of cancer. The present invention also provides processes for the preparation of acid addition salts of sorafenib.
Abstract translation: 本发明提供索拉非尼的酸加成盐的无定形和结晶形式，包含它们的药物组合物及其用于治疗癌症的用途。 本发明还提供了制备索拉非尼的酸加成盐的方法。
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