公开(公告)号：US20120158132A1

公开(公告)日：2012-06-21

申请号：US12969060

申请日：2010-12-15

申请人： Carmen Canovas Vidal ,  Pablo Artal

发明人： Carmen Canovas Vidal ,  Pablo Artal

IPC分类号： A61F2/16 ,  A61B3/107 ,  A61B3/10 ,  A61B3/00

CPC分类号： A61B3/0025 ,  A61B3/10 ,  A61B3/107 ,  A61F2/1613 ,  A61F2/1637 ,  A61F2/164 ,  A61F2240/002

摘要： An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition. The empirically derived regression calculation includes at least a product of the corneal spherical aberration with an empirically derived corneal spherical aberration constant, and a mathematical indication of the at least one biometric parameter or one of the paraxial regression formulas commonly used in clinical practice to calculate IOL power in normal patients.

摘要翻译： 眼内透镜，以及提供眼内透镜的系统和方法，其具有根据包括角膜球面像差的修改的修正回归定制的眼内透镜的至少一个特征。 透镜，系统和方法可以指示以期望的光水平测量眼睛的至少一个生物特征参数，确定眼睛的期望的术后状态，获得眼睛的角膜球面像差，应用至少一个经验导出的回归计算， 以及根据所述至少一个经验导出的回归计算的输出，预测所述眼内透镜的至少一个特征以获得所需的术后状态。 经验导出的回归计算至少包括角膜球面像差与经验衍生的角膜球面像差常数的乘积，以及临床实践中通常用于计算IOL的至少一个生物特征参数或近轴回归公式之一的数学指示 正常患者的功能

公开(公告)号：US07841720B2

公开(公告)日：2010-11-30

申请号：US12175395

申请日：2008-07-17

申请人： Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

发明人： Sverker Norrby ,  Pablo Artal ,  Patricia Ann Piers ,  Marrie Van Der Mooren

IPC分类号： A61B3/10

CPC分类号： A61B3/0025 ,  A61F2/1637 ,  A61F2240/002 ,  G02C7/02 ,  G02C7/028 ,  G02C2202/06 ,  G02C2202/22

摘要： The present invention discloses methods of obtaining ophthalmic lens capable of reducing the aberrations of the eye comprising the steps of characterizing at least one corneal surface as a mathematical model, calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model, selecting the optical power of the intraocular lens. From this information, an ophthalmic lens is modeled so a wavefront arriving from an optical system comprising said lens and corneal model obtains reduced aberrations in the eye. Also disclosed are ophthalmic lenses as obtained by the methods which are capable reducing aberrations of the eye.

摘要翻译： 本发明公开了获得能够减少眼睛像差的眼镜的方法，包括以下步骤：将至少一个角膜表面表征为数学模型，通过使用所述数学模型计算所得到的所述角膜表面的像差，选择 眼内透镜的光学功率。 根据该信息，对眼科镜进行建模，使得从包括所述透镜和角膜模型的光学系统到达的波前获得眼睛中的减少的像差。 还公开了通过能够减少眼睛畸变的方法获得的眼科镜片。

公开(公告)号：US20100195876A1

公开(公告)日：2010-08-05

申请号：US12598834

申请日：2008-05-05

申请人： Pablo Artal Soriano ,  Jaume Pujol Ramo ,  Sergio Oscar Luque ,  Antonio Benito Galindo ,  Guillermo Perez Sanchez

发明人： Pablo Artal Soriano ,  Jaume Pujol Ramo ,  Sergio Oscar Luque ,  Antonio Benito Galindo ,  Guillermo Perez Sanchez

IPC分类号： G06K9/00 ,  A61B3/14

CPC分类号： A61B3/101 ,  A61B3/0025 ,  A61B3/113 ,  A61B3/1176

摘要： The invention relates to a system and method for measuring light diffusion in the eyeball or eye region, by recording and processing retinal images. The inventive system includes a double-pass ophthalmoscopic system having means for correcting low-order aberrations. Said system can be used to record images of the plane of the retina on a CCD camera, the outer part of said images containing information relating to ocular scattering. The aforementioned images can be used to obtain the objective scattering index (OSI), providing the ratio between the energy on the outer part of the image and the energy in the central part, or, alternatively, the modulation transfer function (MTF) area can be used for this purpose once the low frequencies have been filtered. According to the inventive method, the low-order aberrations are corrected before a retinal image or a temporal sequence of retinal images is captured and recorded.

摘要翻译： 本发明涉及通过记录和处理视网膜图像来测量眼球或眼睛区域中的光扩散的系统和方法。 本发明的系统包括具有用于校正低阶像差的装置的双通眼镜系统。 所述系统可用于在CCD照相机上记录视网膜平面的图像，所述图像的外部部分包含与眼睛散射有关的信息。 可以使用上述图像来获得目标散射指数（OSI），提供图像外部的能量与中心部分的能量之间的比率，或者，调制传递函数（MTF）区域可以 一旦低频被过滤就被用于此目的。 根据本发明的方法，在视网膜图像或视网膜图像的时间序列被捕获和记录之前校正低阶像差。

公开(公告)号：US20070258044A1

公开(公告)日：2007-11-08

申请号：US11742996

申请日：2007-05-01

申请人： Sverker Norrby ,  Pablo Artal ,  Patricia Piers ,  Marrie Mooren

发明人： Sverker Norrby ,  Pablo Artal ,  Patricia Piers ,  Marrie Mooren

IPC分类号： A61B3/107

CPC分类号： A61B3/0025 ,  A61F2/1637 ,  A61F2240/002 ,  G02C7/02 ,  G02C7/028 ,  G02C2202/06 ,  G02C2202/22

摘要： The present invention discloses methods of obtaining ophthalmic lens capable of reducing the aberrations of the eye comprising the steps of characterizing at least one corneal surface as a mathematical model, calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model, selecting the optical power of the intraocular lens. From this information, an ophthalmic lens is modeled so a wavefront arriving from an optical system comprising said lens and corneal model obtains reduced aberrations in the eye. Also disclosed are ophthalmic lenses as obtained by the methods which are capable reducing aberrations of the eye.

摘要翻译： 本发明公开了获得能够减少眼睛像差的眼镜的方法，包括以下步骤：将至少一个角膜表面表征为数学模型，通过使用所述数学模型计算所得到的所述角膜表面的像差，选择 眼内透镜的光学功率。 根据该信息，对眼科镜进行建模，使得从包括所述透镜和角膜模型的光学系统到达的波前获得眼睛中的减少的像差。 还公开了通过能够减少眼睛畸变的方法获得的眼科镜片。

公开(公告)号：US06199986B1

公开(公告)日：2001-03-13

申请号：US09421892

申请日：1999-10-21

申请人： David R. Williams ,  William J. Vaughn ,  Benjamin D. Singer ,  Heidi Hofer ,  Geun-Young Yoon ,  Pablo Artal ,  Juan Luis Arag{dot over (o)}n ,  Pedro Prieto ,  Fernando Vargas

发明人： David R. Williams ,  William J. Vaughn ,  Benjamin D. Singer ,  Heidi Hofer ,  Geun-Young Yoon ,  Pablo Artal ,  Juan Luis Arag{dot over (o)}n ,  Pedro Prieto ,  Fernando Vargas

IPC分类号： A61B310

CPC分类号： A61B3/1015 ,  G01J9/00

摘要： A wavefront aberration of an eye is determined, e.g., in real time. The eye is illuminated, and the light reflected from the retina is converted into spots with a device such as a Hartmann-Shack detector. The displacement of each spot from where it would be in the absence of aberration allows calculation of the aberration. Each spot is located by an iterative technique in which a corresponding centroid is located in a box drawn on the image data, a smaller box is defined around the centroid, the centroid is located in the smaller box, and so on. The wavefront aberration is calculated from the centroid locations by using a matrix in which unusable data can be eliminated simply by eliminating rows of the matrix. Aberrations for different pupil sizes are handled in data taken for a single pupil size by renormalization.

摘要翻译： 例如实时地确定眼睛的波前像差。 眼睛被照亮，从视网膜反射的光被转换成具有诸如Hartmann-Shack检测器的装置的斑点。 在不存在像差的情况下，每个光斑的位移可以计算像差。 每个点通过迭代技术来定位，其中对应的质心位于图像数据上绘制的框中，围绕质心定义较小的框，质心位于较小的框中，依此类推。 通过使用矩阵来计算波前像差，其中可以通过消除矩阵的行来消除不可用的数据。 通过重新归一化处理单个瞳孔大小的数据来处理不同瞳孔大小的畸变。