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    REDUCED COENZYME Q10-CONTAINING COMPOSITION WHICH IS STABLE AGAINST OXIDATION, AND METHOD FOR STABILIZATION OF REDUCED COENZYME Q10
    31.
    发明申请
    REDUCED COENZYME Q10-CONTAINING COMPOSITION WHICH IS STABLE AGAINST OXIDATION, AND METHOD FOR STABILIZATION OF REDUCED COENZYME Q10 有权
    减少含氧化合物Q10的组合物对氧化物有稳定作用，以及降低COENZYME Q10稳定化的方法

    公开(公告)号：US20090181002A1

    公开(公告)日：2009-07-16

    申请号：US12092925

    申请日：2006-11-07

    Applicant: Takahiro Ueda ,  Shiro Kitamura

    Inventor： Takahiro Ueda ,  Shiro Kitamura

    IPC: A61K38/43 ,  A61P43/00

    CPC classification number: A61K9/4858 ,  A61K9/4875 ,  A61K31/05

    Abstract: The present invention provides a method for stabilization of reduced coenzyme Q10 characterized by concurrently containing a propylene glycol fatty acid ester in a composition containing reduced coenzyme Q10, and a composition containing reduced coenzyme Q10 and a propylene glycol fatty acid ester as essential constituting ingredients. According to the present invention, reduced coenzyme Q10, which is useful as a food, food with nutrient function claims, food for specified health use, nutritional supplement, nutritional product, animal drug, drink, feed, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like can be stabilized especially without being made into a complicated composition.

    Abstract translation: 本发明提供还原型辅酶Q10的稳定化方法，其特征在于含有还原型辅酶Q10的组合物中含有丙二醇脂肪酸酯，还含有还原型辅酶Q10和丙二醇脂肪酸酯作为必要构成成分的组合物。 根据本发明，可用作食品的具有营养功能的食品的还原型辅酶Q10，用于特定健康用途的食物，营养补充剂，营养产品，动物药物，饮料，饲料，化妆品，药​​物产品，治疗药物， 预防药物等可以稳定化，而不会形成复杂的组合物。

    Processes for producing coenzyme Q10
    32.
    发明申请
    Processes for producing coenzyme Q10 有权
    生产辅酶Q10的方法

    公开(公告)号：US20080171373A1

    公开(公告)日：2008-07-17

    申请号：US11981181

    申请日：2007-10-31

    Applicant: Kazuyoshi Yajima ,  Takahisa Kato ,  Akihisa Kanda ,  Shiro Kitamura ,  Yasuyoshi Ueda

    Inventor： Kazuyoshi Yajima ,  Takahisa Kato ,  Akihisa Kanda ,  Shiro Kitamura ,  Yasuyoshi Ueda

    IPC: C12N9/00

    CPC classification number: C12P7/66 ,  C12P7/22

    Abstract: The present invention relates to a process for producing reduced coenzyme Q10 which comprises obtaining microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus-produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10 which comprises either recovering oxidized coenzyme Q10 after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10 from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10 thereafter. According to the processes of the present invention, reduced coenzyme Q10 and oxidized coenzyme Q10 can be produced simply on the industrial scale.

    Abstract translation: 本发明涉及一种还原型辅酶Q 10的制备方法，该方法包括：将全部还原型辅酶Q 10的比例不小于70摩尔％的还原型辅酶Q 10 辅酶Q 10，任选地破坏细胞并回收如此生产的还原型辅酶Q 10。 本发明还涉及一种生产氧化型辅酶Q 10的方法，其包括在氧化上述微生物细胞或其破坏的产物之后回收氧化型辅酶Q 10，或 从上述微生物细胞中回收还原型辅酶Q 10 N或其破坏产物，从而氧化由此得到的还原型辅酶Q 10。 根据本发明的方法，可以简单地在工业规模上制备还原型辅酶Q 10和氧化型辅酶Q 10。

    Reduced coenzyme Q10 crystal with excellent stability and composition containing said reduced coenzyme Q10 crystal
    33.
    发明授权
    Reduced coenzyme Q10 crystal with excellent stability and composition containing said reduced coenzyme Q10 crystal 有权
    具有优异稳定性的还原型辅酶Q10晶体，含有所述还原型辅酶Q10晶体的组合物

    公开(公告)号：US07358402B2

    公开(公告)日：2008-04-15

    申请号：US10938431

    申请日：2004-09-09

    Applicant: Takahiro Ueda ,  Shiro Kitamura ,  Taizo Kawabe ,  Hideyuki Kishida ,  Yasuyoshi Ueda

    Inventor： Takahiro Ueda ,  Shiro Kitamura ,  Taizo Kawabe ,  Hideyuki Kishida ,  Yasuyoshi Ueda

    IPC: C07C43/20 ,  C07C43/215

    CPC classification number: C07C43/23 ,  A23L33/10

    Abstract: The present invention provides a reduced coenzyme Q10 crystal with excellent stability and a composition containing said reduced coenzyme Q10 crystals.According to the present invention, after dissolving reduced coenzyme Q10 in a fat and oil, it is cooled, making it possible to obtain reduced coenzyme Q10 crystals with excellent stability and which exhibit an x-ray diffraction pattern (using a CuKα emission line) that differs from ordinary reduced coenzyme Q10 crystals. Moreover, said crystals are also excellent in bioabsorbability.

    Abstract translation: 本发明提供了具有优异稳定性的还原型辅酶Q 10 O 2结晶和含有所述还原型辅酶Q 10 O 2结晶的组合物。 根据本发明，在将脂肪和油中的还原型辅酶Q 10 O溶解后，将其冷却，可以获得具有优异稳定性的还原型辅酶Q 10 N 2结晶， 其表现出与普通还原​​型辅酶Q 10 N结晶不同的x射线衍射图（使用CuKα发射谱线）。 此外，所述晶体的生物吸收性也优异。

    Method of producing reduced coenzyme q10
    34.
    发明授权
    Method of producing reduced coenzyme q10 有权
    还原型辅酶Q10的制备方法

    公开(公告)号：US07105709B2

    公开(公告)日：2006-09-12

    申请号：US10483643

    申请日：2002-07-15

    Applicant: Takahiro Ueda ,  Shiro Kitamura ,  Yasuyoshi Ueda

    Inventor： Takahiro Ueda ,  Shiro Kitamura ,  Yasuyoshi Ueda

    IPC: C07C35/18 ,  C07C50/04

    CPC classification number: C07C41/26 ,  C07C43/23

    Abstract: The present invention relates to a method of conveniently and efficiently producing high-quality reduced coenzyme Q10 which is useful as an ingredient in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. This method is suitable for industrial production thereof.A method of producing a reduced coenzyme Q10 which comprises reducing an oxidized coenzyme Q10 in an aqueous medium with the use of dithionous acid or a salt thereof, said reduction being carried out in the coexistence of a salt and/or under deoxygenated atmosphere, and at pH of 7 or below. Thus, the formation of the oxidized coenzyme Q10 as a by-product due to oxidation can be minimized, thereby giving reduced coenzyme Q10 having excellent qualities in a high yield.

    Abstract translation: 本发明涉及一种方便有效地生产高质量还原型辅酶Q 10的方法，其可用作食品中的成分，功能营养食品，特定保健食品，营养补充剂，营养物质，动物药物 饮料，饲料，化妆品，药​​品，补救措施，预防药品等。该方法适用于工业生产。 还原型辅酶Q 10的制备方法，其包括使用二硫酸或其盐在水性介质中还原氧化型辅酶Q 10，所述还原物被携带 在盐的共存和/或在脱氧气氛下，以及在7或更低的pH下。 因此，由于氧化而形成作为副产物的氧化型辅酶Q 10可以最小化，从而以高产率得到具有优异品质的还原型辅酶Q 10。

    Method for preserving reduced coenzyme Q10
    35.
    发明申请
    Method for preserving reduced coenzyme Q10 有权
    保留还原型辅酶Q10的方法

    公开(公告)号：US20060153911A1

    公开(公告)日：2006-07-13

    申请号：US11315161

    申请日：2005-12-23

    Applicant: Takahiro Ueda ,  Tadao Ono ,  Shiro Kitamura ,  Yasuyoshi Ueda

    Inventor： Takahiro Ueda ,  Tadao Ono ,  Shiro Kitamura ,  Yasuyoshi Ueda

    IPC: A61K9/48 ,  C07C29/94 ,  C12N9/00 ,  C07C37/88

    CPC classification number: A61K9/4816

    Abstract: The present invention has its object to provide a method for stably preserving a capsule containing reduced coenzyme Q10, which is useful as foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. The present invention relates to a method for preserving reduced coenzyme Q10 which comprises producing or obtaining a capsule containing reduced coenzyme Q10, and controlling environment surrounding the capsule to a relative humidity of not less than 0% but not more than 60%. According to this method, reduced coenzyme Q10 can be preserved stably, without requiring huge cost and labor, or special equipment.

    Abstract translation: 本发明的目的是提供一种用于稳定保存含有还原型辅酶Q 10的胶囊的方法，所述还原型辅酶Q 10可用作食品，功能营养食品，特定保健食品，营养补充剂，营养物质，动物药物， 饮料，饲料，化妆品，药​​物，补救剂，预防药物等。本发明涉及一种保存还原型辅酶Q 10的方法，其包括制备或获得含有还原型辅酶Q 10的胶囊 并且将胶囊周围的环境控制在不小于0％但不大于60％的相对湿度。 根据该方法，可以稳定地保持还原型辅酶Q 10，而不需要巨大的成本和劳动力或专用设备。

    Optical measuring head
    37.
    发明授权
    Optical measuring head 失效
    光学测头

    公开(公告)号：US4816670A

    公开(公告)日：1989-03-28

    申请号：US98332

    申请日：1987-09-18

    Applicant: Shiro Kitamura ,  Junji Koizumi ,  Kiyoshi Yamada

    Inventor： Shiro Kitamura ,  Junji Koizumi ,  Kiyoshi Yamada

    IPC: G01N21/47 ,  G02B6/00

    CPC classification number: G01N21/474

    Abstract: An optical measuring head which includes a cylindrical portion having a circular cross section, a plurality of light projecting fibers axially disposed in the cylindrical portion through a predetermined distance, a light receiving fiber provided along an axis of the cylindrical portion, and a convex lens formed, at its outer peripheral portion, with a light receiving face for receiving the light from the light projecting fibers and directing the light through the lens so that the light will be incident upon a flat surface of the lens adjacent an object to be measured, through an angle smaller than a critical angle whereby the light will not be reflected by the flat surface, and disposed at a position coaxial with the light receiving fiber for focusing on a forward end face of the light receiving fiber.

    Abstract translation: 一种光学测量头，其包括具有圆形截面的圆柱形部分，多个沿着圆柱形部分轴向设置预定距离的光投射光纤，沿着圆柱形部分的轴线设置的光接收光纤和形成的凸透镜 在其外周部分具有用于接收来自光投射光纤的光并将光引导通过透镜的光接收面，使得光将入射到邻近被测物体的透镜的平坦表面上，通过 小于临界角度的角度，由此光不会被平坦表面反射，并且设置在与光接收光纤同轴的位置处以聚焦在光接收光纤的前端面上。

    Bore measuring system
    38.
    发明授权
    Bore measuring system 失效
    孔测量系统

    公开(公告)号：US4687328A

    公开(公告)日：1987-08-18

    申请号：US582845

    申请日：1984-02-23

    Applicant: Takashi Shiraishi ,  Shiro Kitamura

    Inventor： Takashi Shiraishi ,  Shiro Kitamura

    IPC: G01B11/08 ,  G01B11/12 ,  G01B11/02

    CPC classification number: G01B11/12

    Abstract: A bore measuring system to optically measure the diameter of hole on thin boards, such as printed circuit boards. The bore measuring system of the invention is so contrived as to irradiate a hole to be measured, to project the light through the hole onto the receiving surface of the image sensor and to indicate the diameter of the hole by converting the output from the image sensor, corresponding to the size of the image, into a numerical figure. Unlike the conventional methods, measurement is possible simply by irradiating the hole to be measured without inserting any pin or measuring rod of a hole gauge into the hole, and without projecting the image to be measured onto a screen. Accordingly, the operation is quite simple and the measuring time can be shortened, yet measuring errors can be avoided. Moreover, the automatic display of hole diameter in a numerical value eliminates the reading errors which often occur with conventional methods.

    Abstract translation: 孔径测量系统，用于光学测量诸如印刷电路板的薄板上的孔的直径。 本发明的钻孔测量系统被设计成照射要测量的孔，以将光通过孔突出到图像传感器的接收表面上，并通过转换来自图像传感器的输出来指示孔的直径 ，对应于图像的大小，成为数字图。 与常规方法不同，可以简单地通过在孔中照射要测量的孔而不将孔规的任何销或测量棒插入孔中，并且不将待测量的图像投影到屏幕上。 因此，操作非常简单，并且可以缩短测量时间，但是可以避免测量误差。 此外，以数值自动显示孔径消除了常规方法常常发生的读取误差。

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