Cell potential measurement apparatus having a plurality of microelectrodes
    32.
    再颁专利
    Cell potential measurement apparatus having a plurality of microelectrodes 有权
    具有多个微电极的电池电位测量装置

    公开(公告)号:USRE40209E1

    公开(公告)日:2008-04-01

    申请号:US09688077

    申请日:2000-10-13

    IPC分类号: C12M1/34

    CPC分类号: C12M41/46 G01N33/48728

    摘要: A cell potential measurement apparatus, which uses a planar electrode enabling a multi-point simultaneous measurement of potential change arising from cell activities, is provided which can conduct measurements accurately and efficiently as well as can improve convenience of arranging measurement results. According to the configuration of the cell potential measurement apparatus of this invention, it includes an integrated cell holding instrument, which includes a planar electrode provided with a plurality of microelectrodes arranged in a matrix form on the surface of a substrate, a cell holding part for placing cells thereon, drawer patterns from the microelectrodes, and electric contact points for outside connections; an optical observation means for optical observations of cells; a stimulation signal supply means to be connected to the cell holding instrument for providing electric stimulation to the cells; and a signal processing means to be connected to the cell holding instrument for processing an output signal arising from electric physiological activities of the cells. It is preferable that a cell culturing means is also provided for maintaining a culture atmosphere of the cells placed on the integrated cell holding instrument.

    摘要翻译: 提供一种电池电位测量装置,其使用能够进行多点同时测​​量由电池活动引起的电位变化的平面电极,其可以精确且有效地进行测量,并且可以提高排列测量结果的便利性。 根据本发明的电池电位测量装置的结构,它包括一个集成的电池保持仪器,它包括一个平面电极,该平面电极设置有以矩阵形式布置在基片表面上的多个微电极, 在其上放置电池,来自微电极的抽屉图案和用于外部连接的电接触点; 用于细胞光学观察的光学观察装置; 刺激信号提供装置,连接到用于向细胞提供电刺激的细胞保持仪器; 以及信号处理装置,其连接到用于处理由电池的电生理活动引起的输出信号的电池保持装置。 还优选还设置有用于维持放置在集成电池保持器具上的电池的培养气氛的细胞培养装置。

    Image observation apparatus
    33.
    发明授权
    Image observation apparatus 失效
    图像观察装置

    公开(公告)号:US07030838B1

    公开(公告)日:2006-04-18

    申请号:US08988537

    申请日:1997-12-10

    IPC分类号: G09G5/00

    CPC分类号: G06F3/012 G06F3/011

    摘要: An image observation device which is so arranged that a user can look an image in through an ocular window thereof with the device being fitted to the user's head for example, that the image changes in linkage with movement of the user's head, and that unnecessary change of the image is prevented during the observation. The image observation device includes an eye access detector for detecting whether the user's eyes approach thereto or not, and includes, a controller by the operation of which the image changes in linkage with movement of the user's head only if the eye access detector detects that the user's eyes approach thereto, and by the operation of which the image does not change in linkage with movement of the user's head if the eye access detector does not detect that the user's eyes approach thereto.

    摘要翻译: 一种图像观察装置,其被设置为使得用户可以通过其目视窗口将装置安装到用户头部,例如,图像与用户头部的移动相关联地改变,并且不必要的改变 在观察期间防止了图像。 图像观察装置包括用于检测用户的眼睛是否接近的眼睛访问检测器,并且包括控制器,只有当眼睛访问检测器检测到所述眼睛访问检测器检测到该图像时,通过与用户头部的移动相关联地改变图像的操作 用户的眼睛接近,并且如果眼睛访问检测器没有检测到用户的眼睛接近,则图像不与用户头部的移动相关联地改变的操作。

    Method for measuring physiocochemical properties of tissues of cells, method for examining chemicals, and apparatus therefor
    34.
    发明授权
    Method for measuring physiocochemical properties of tissues of cells, method for examining chemicals, and apparatus therefor 失效
    用于测量细胞组织的生理化学性质的方法,用于检查化学品的方法及其装置

    公开(公告)号:US06890762B1

    公开(公告)日:2005-05-10

    申请号:US08913811

    申请日:1997-01-24

    摘要: A method of measuring the physical and chemical properties of tissue or cells and a device for the same is provided, with which the physical and chemical environment of the tissue or cells can be changed arbitrarily corresponding to experimental necessities. The device comprises a system 40 for keeping the physical and chemical environment surrounding the biological tissue or cells constant, a system 50 for arbitrarily changing the physical and chemical environment, observation systems 10 and 20 for observing the physical and chemical properties of the tissue or cells, and a system 30 for comparing the change of the physical and chemical properties of the tissue or cells before and after changing the physical and chemical environment. The observation system 10 is a potential measurement device for measuring the electrophysiological properties of the tissue or cells. This device comprises an integrated cell placement device 1 provided with a plurality of microelectrodes 11 on a substrate, a cell placement portion 6 for placing the tissue or cells on the microelectrodes 11, and a wiring pattern 12 for applying an electrical signal to the microelectrodes 11 and extracting an electrical signal from the microelectrodes 11.

    摘要翻译: 提供了一种测量组织或细胞的物理和化学性质的方法及其装置,通过该方法可以根据实验需要任意改变组织或细胞的物理和化学环境。 该装置包括用于保持生物组织或细胞周围的物理和化学环境恒定的系统40,用于任意改变物理和化学环境的系统50,用于观察组织或细胞的物理化学性质的观察系统10和20 以及用于比较在改变物理和化学环境之前和之后组织或细胞的物理和化学性质的变化的系统30。 观察系统10是用于测量组织或细胞的电生理特性的电位测量装置。 该装置包括在基板上设置有多个微电极11的集成电池放置装置1,用于将组织或电池放置在微电极11上的电池放置部分6以及用于向微电极11施加电信号的布线图案12 以及从微电极11提取电信号。

    Process and apparatus for filling N2 gas into tire
    35.
    发明授权
    Process and apparatus for filling N2 gas into tire 有权
    将N2气充入轮胎的工艺和装置

    公开(公告)号:US06374869B2

    公开(公告)日:2002-04-23

    申请号:US09828930

    申请日:2001-04-10

    IPC分类号: B65B104

    CPC分类号: B60S5/046

    摘要: A process for filling N2 gas into a tire assembled onto a rim to hold a recommended internal pressure comprises discharging air inside the tire prior to the filling of N2 gas to render the inside of the tire into a state lower than atmospheric pressure and filling N2 gas into such a tire. An apparatus for carrying out the above process comprises a single inlet path, at least two outlet paths and a membrane module for separating air introduced through the inlet path into O2 gas and N2 gas and feeding these gases into respective outlet paths, wherein an outlet path for feeding N2 gas in the outlet paths is connected at its top to a valve for inflating a tire assembled onto a rim under an internal pressure and a discharge path for discharging air inside the tire prior to the filling of N2 gas is provided on the way of such an outlet path.

    摘要翻译: 将N 2气体填充到装配到轮辋上的轮胎以保持推荐的内部压力的方法包括在填充N 2气体之前排出轮胎内的空气,使轮胎内部处于低于大气压的状态并填充N 2气体 进入这样的轮胎。 用于执行上述过程的装置包括单个入口路径,至少两个出口路径和用于将通过入口路径引入的空气分离成O 2气体和N 2气体并将这些气体供给到相应出口路径中的膜组件,其中出口路径 用于在出口路径中供给N 2气体的顶部连接到用于在内部压力下组装到轮辋上的轮胎充气的阀,并且在途中提供用于在填充N 2气体之前排出轮胎内的空气的排出路径 的出口路径。

    Tire air-pressure abnormality alarming device and method thereof
    36.
    发明授权
    Tire air-pressure abnormality alarming device and method thereof 失效
    轮胎气压异常报警装置及其方法

    公开(公告)号:US06323765B1

    公开(公告)日:2001-11-27

    申请号:US09129403

    申请日:1998-08-05

    IPC分类号: B60C2300

    CPC分类号: B60C23/061

    摘要: A tire air-pressure abnormality alarming device for informing decrease in air-pressure of tires attached to a four-wheeled vehicle, characterized in that the device prohibits start of initializing operations for updating stored values for physical amounts related to tires or wheels in the case where air-pressures of the tires are judged to be normal, if air-pressure abnormality of a tire is being alarmed. Initialization is accepted only after the internal pressure has become normal, whereby erroneous initialization with any tire being in a decompressed condition can be prevented. Thus, normal operations for detecting decompression of a tire can be maintained.

    摘要翻译: 一种轮胎气压异常报警装置,用于通知附着在四轮车辆上的轮胎的气压降低,其特征在于,该装置禁止开始初始化操作,用于更新与该轮胎或车轮相关的物理量的存储值 如果轮胎的气压异常被警告,则认为轮胎的空气压力正常。 初始化仅在内部压力变得正常之后被接受,由此可以防止任何轮胎处于减压状态的错误初始化。 因此,可以保持用于检测轮胎的减压的正常操作。

    Scanning type image viewing optical system
    37.
    发明授权
    Scanning type image viewing optical system 失效
    扫描型影像光学系统

    公开(公告)号:US6097526A

    公开(公告)日:2000-08-01

    申请号:US316818

    申请日:1999-05-21

    摘要: A scanning-type image viewing optical system has a light source for emitting luminous flux; a main scanning means for scanning luminous flux in a first direction; a sub-scanning means for scanning luminous flux in a second direction different from the first direction; and an eyepiece lens for directing luminous flux scanned by the two scanning means to the pupil of an observer, wherein the main scanning means has a conjugate relationship with the pupil position of the observer via the eyepiece lens, and when the pupil diameter, i.e., the luminous flux diameter of the incident luminous flux at the pupil position of the observer, is designated d and the main scan diameter, i.e., the luminous flux diameter exiting the main scanning means, is designated d', the conjugate magnification .beta. calculated by d/d' satisfies the conditional equation 1.2.ltoreq..beta..

    摘要翻译: 扫描型图像观察光学系统具有用于发射光通量的光源; 主扫描装置,用于沿第一方向扫描光通量; 用于沿与第一方向不同的第二方向扫描光通量的副扫描装置; 以及用于将由两个扫描装置扫描的光束引导到观察者的瞳孔的目镜,其中主扫描装置经由目镜透镜与观察者的瞳孔位置具有共轭关系,并且当瞳孔直径 在观察者的瞳孔位置处的入射光通量的光束直径被指定为d,主扫描直径(即,将主扫描装置的光束直径)指定为d',由d计算的共轭倍率β / d'满足条件方程式1.2

    Display device
    38.
    发明授权
    Display device 失效
    显示设备

    公开(公告)号:US5993000A

    公开(公告)日:1999-11-30

    申请号:US120188

    申请日:1998-07-22

    CPC分类号: A61B3/112

    摘要: A display device provides a virtual image for eyes of an observer. The display has a light source which emits light based on an image signal, scanner which scans the light, an eyepiece optical system which projects the scanned light onto an eye of the observer as a virtual image, detector which detects a pupil size of the observer, and regulator means which regulates a quantity of light projected onto the eye of the observer based on the detected pupil size.

    摘要翻译: 显示装置为观察者的眼睛提供虚拟图像。 显示器具有基于图像信号发光的光源,扫描光的扫描仪,将扫描光投影到观察者的眼睛上的目镜光学系统作为虚像,检测器观察者的瞳孔尺寸 以及调节装置,其基于检测到的瞳孔大小来调节投影到观察者的眼睛上的光量。

    Cell potential measurement apparatus having a plurality of
microelectrodes
    40.
    发明授权
    Cell potential measurement apparatus having a plurality of microelectrodes 失效
    具有多个微电极的电池电位测量装置

    公开(公告)号:US5563067A

    公开(公告)日:1996-10-08

    申请号:US464116

    申请日:1995-06-05

    CPC分类号: G01N33/4836 C12M41/46

    摘要: A cell potential measurement apparatus, which uses a planar electrode enabling a multi-point simultaneous measurement of potential change arising from cell activities, is provided which can conduct measurements accurately and efficiently as well as can improve convenience of arranging measurement results. According to the configuration of the cell potential measurement apparatus of this invention, it includes an integrated cell holding instrument, which includes a planar electrode provided with a plurality of microelectrodes arranged in a matrix form on the surface of a substrate, a cell holding part for placing cells thereon, drawer patterns from the microelectrodes, and electric contact points for outside connections; an optical observation means for optical observations of cells; a stimulation signal supply means to be connected to the cell holding instrument for providing electric stimulation to the cells; and a signal processing means to be connected to the cell holding instrument for processing an output signal arising from electric physiological activities of the cells. It is preferable that a cell culturing means is also provided for maintaining a culture atmosphere of the cells placed on the integrated cell holding instrument.

    摘要翻译: 提供一种电池电位测量装置,其使用能够进行多点同时测​​量由电池活动引起的电位变化的平面电极,其可以精确且有效地进行测量,并且可以提高排列测量结果的便利性。 根据本发明的电池电位测量装置的结构,它包括一个集成的电池保持仪器,它包括一个平面电极,该平面电极设置有以矩阵形式布置在基片表面上的多个微电极, 在其上放置电池,来自微电极的抽屉图案和用于外部连接的电接触点; 用于细胞光学观察的光学观察装置; 刺激信号提供装置,连接到用于向细胞提供电刺激的细胞保持仪器; 以及信号处理装置,其连接到用于处理由电池的电生理活动引起的输出信号的电池保持装置。 还优选还设置有用于维持放置在集成电池保持器具上的电池的培养气氛的细胞培养装置。