公开(公告)号：US07335153B2

公开(公告)日：2008-02-26

申请号：US10192352

申请日：2002-07-09

Applicant: Michael Seul ,  Chiu Wo Chau ,  Hui Huang ,  Sukanta Banerjee ,  Jiacheng Yang ,  Ye Hong

Inventor： Michael Seul ,  Chiu Wo Chau ,  Hui Huang ,  Sukanta Banerjee ,  Jiacheng Yang ,  Ye Hong

IPC: C40B20/02

CPC classification number: C12Q1/6837 ,  B01J19/0046 ,  B01J2219/00274 ,  B01J2219/00317 ,  B01J2219/00466 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00545 ,  B01J2219/00648 ,  B01J2219/00662 ,  G01N33/54306 ,  C12Q2563/149

Abstract: This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.

Abstract translation: 本发明提供高单位密度的微粒阵列和组装这种阵列的方法。 阵列中的微粒可以用给定靶分析物特异性的化学或生物实体来官能化。 本发明的高单位密度阵列形成在芯片上，芯片可以根据本文所述的方法组合以形成多芯片阵列。 本发明的芯片和/或多芯片阵列可用于化学和生物测定。

公开(公告)号：US20070291223A1

公开(公告)日：2007-12-20

申请号：US11761272

申请日：2007-06-11

Applicant: Charlie Chen ,  Ye Hong ,  Nick Manesis

Inventor： Charlie Chen ,  Ye Hong ,  Nick Manesis

IPC: G02C7/04

CPC classification number: C08L83/14 ,  C08F283/12 ,  C08F290/068 ,  C08L51/085 ,  G02B1/043 ,  C08L2666/02

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products produced from a polymerizable composition comprising a combination of particular components. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract translation: 具有眼睛可接受的表面润湿性的硅酮水凝胶隐形眼镜是由包含特定组分的组合的可聚合组合物制备的预提取聚合的硅氧水凝胶隐形眼镜产品获得的。 硅酮水凝胶隐形眼镜可以从非极性树脂基隐形眼镜模具获得，而不用表面处理或聚合润湿剂的互穿聚合物网络获得。 还描述了相关的透镜产品，可聚合组合物和方法。

公开(公告)号：US09140908B2

公开(公告)日：2015-09-22

申请号：US13982032

申请日：2012-02-23

Applicant: Junhao Ge ,  Yuwen Liu ,  Charlie Chen ,  Yuan Xu ,  Ye Hong ,  Hongjin Qiu

Inventor： Junhao Ge ,  Yuwen Liu ,  Charlie Chen ,  Yuan Xu ,  Ye Hong ,  Hongjin Qiu

IPC: G02C7/04 ,  G02B1/04

CPC classification number: G02C7/049 ,  G02B1/043 ,  C08L83/04 ,  C08L101/14

Abstract: Silicone hydrogel contact lenses are formed from the reaction product of a polymerizable composition comprising at least one hydrophilic vinyl amide-containing monomer, at least one acrylate-containing siloxane monomer, and at least one hydrophilic vinyl ether-containing monomer. The contact lenses have ophthalmically-acceptable surface wettability and can be manufactured without the use of volatile organic solvents.

Abstract translation: 硅氧水凝胶隐形眼镜由包含至少一种含亲水性乙烯基酰胺的单体，至少一种含丙烯酸酯的硅氧烷单体和至少一种含亲水性乙烯基醚的单体的可聚合组合物的反应产物形成。 隐形眼镜具有眼科可接受的表面润湿性，并且可以在不使用挥发性有机溶剂的情况下制造。

公开(公告)号：US08865789B2

公开(公告)日：2014-10-21

申请号：US13404035

申请日：2012-02-24

Applicant: Li Yao ,  Ye Hong ,  Yuwen Liu ,  Charlie Chen ,  Charles A. Francis ,  Arthur Back

Inventor： Li Yao ,  Ye Hong ,  Yuwen Liu ,  Charlie Chen ,  Charles A. Francis ,  Arthur Back

IPC: C08L101/14 ,  B65B55/02 ,  G02C7/04 ,  C08G77/04 ,  G02B1/04

CPC classification number: G02B1/043 ,  C08L83/12 ,  C08L101/14 ,  C08L33/10 ,  C08L33/08

Abstract: Silicone hydrogel contact lenses that have good dimensional stability, are ophthalmically-acceptable, and can be manufactured without the use of alcohol solvents are formed from the reaction product of a polymerizable composition comprising at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 2,000; at least one bi-functional acrylate-containing siloxane monomer having a molecular weight of at least 3,000; and at least one hydrophilic vinyl-containing monomer, wherein the polymerizable composition has a molar ratio of total amount of mono-functional acrylate-containing siloxane monomer to total amount of bi-functional acrylate-containing siloxane monomer of at least 30:1, respectively.

Abstract translation: 由可聚合组合物的反应产物形成具有良好的尺寸稳定性的眼科学可接受的硅酮水凝胶隐形眼镜，并且可以制造不含醇溶剂的可聚合组合物，该可聚合组合物包含至少一种含单分子丙烯酸酯的含有单官能丙烯酸酯的硅氧烷单体 重量小于2000; 至少一种分子量至少为3,000的含二官能丙烯酸酯的硅氧烷单体; 和至少一种亲水性含乙烯基单体，其中所述可聚合组合物的含单体官能丙烯酸酯的硅氧烷单体的总量与含二官能丙烯酸酯的硅氧烷单体的总量的摩尔比分别为至少30:1 。

公开(公告)号：US08820928B2

公开(公告)日：2014-09-02

申请号：US13404033

申请日：2012-02-24

Applicant: Arthur Back ,  David Robert Morsley ,  Richard Rogers ,  Sarah Almond ,  Charlie Chen ,  Yuwen Liu ,  Charles A. Francis ,  Ye Hong

Inventor： Arthur Back ,  David Robert Morsley ,  Richard Rogers ,  Sarah Almond ,  Charlie Chen ,  Yuwen Liu ,  Charles A. Francis ,  Ye Hong

IPC: G02C7/04 ,  C08L83/04 ,  G02B1/04 ,  C08G77/46 ,  C08G77/20

CPC classification number: C08L83/04 ,  C08G77/20 ,  C08G77/46 ,  G02B1/043 ,  C08L101/14 ,  C08L83/12

Abstract: Silicone hydrogel contact lenses are produced without using volatile organic solvents to extract materials from the polymerized contact lens bodies, and instead are washed with aqueous liquids. The silicone hydrogel contact lenses so produced have ophthalmically wettable lens surfaces such that less than five percent of a batch of twenty or more such silicone hydrogel contact lenses have visually identifiable non-wetting spots when the contact lenses are located on eyes of subjects.

Abstract translation: 制造硅氧烷水凝胶隐形眼镜，而不使用挥发性有机溶剂从聚合的隐形眼镜体提取物质，而是用含水液体洗涤。 如此制造的硅酮水凝胶隐形眼镜具有眼睛可润湿的透镜表面，使得当隐形眼镜位于受试者的眼睛上时，少于一批二十或更多个这种硅氧水凝胶隐形眼镜的百分之五具有视觉上可识别的非润湿斑点。

公开(公告)号：US20140018465A1

公开(公告)日：2014-01-16

申请号：US13985109

申请日：2012-02-23

Applicant: Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Charles A. Francis ,  Li Yao ,  Arthur Back

Inventor： Yuwen Liu ,  Charlie Chen ,  Ye Hong ,  Charles A. Francis ,  Li Yao ,  Arthur Back

IPC: G02B1/04

CPC classification number: G02B1/043 ,  C08F283/065 ,  C08L51/085 ,  C08L101/14

Abstract: Silicone hydrogel contact lenses having a high water content are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer having a number average molecular weight of at least 7,000 daltons, and at least one vinyl-containing cross-linking agent. The lenses have average equilibrium water contents from about 30% wt/wt to about 70% wt/wt when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract translation: 描述了具有高水含量的硅氧烷水凝胶隐形眼镜。 透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。 透镜还包括衍生自数均分子量为至少7,000道尔顿的第二硅氧烷单体的单元和至少一种含乙烯基交联剂。 当完全水合时，透镜具有约30重量％至约70重量％的平均水含量。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

公开(公告)号：US08445614B2

公开(公告)日：2013-05-21

申请号：US13404034

申请日：2012-02-24

Applicant: Charles A. Francis ,  Ying Zheng ,  Yuan Xu ,  Li Yao ,  Arthur Back ,  Ye Hong ,  Charlie Chen

Inventor： Charles A. Francis ,  Ying Zheng ,  Yuan Xu ,  Li Yao ,  Arthur Back ,  Ye Hong ,  Charlie Chen

IPC: C08F230/08 ,  C08F290/06 ,  G02B1/04

CPC classification number: C08F230/08 ,  C08F222/1006

Abstract: Dimensionally stable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer represented by formula (2): wherein R1 of formula (2) is selected from either hydrogen atom or a methyl group; R2 of formula (2) is selected from either of hydrogen atom or a hydrocarbon group having 1 to 4 carbon atoms; m of formula (2) represents an integer of from 0 to 10; n of formula (2) represents an integer of from 4 to 100; a and b represent integers of 1 or more; a+b is equal to 20-500; b/(a+b) is equal to 0.01-0.22; the configuration of siloxane units includes a random configuration, the second siloxane monomer having a number average molecular weight of at least 3,000 daltons that is present in the polymerizable composition in an amount such that ratio of the first siloxane monomer to the second siloxane monomer is at least 2:1 based on unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract translation: 描述了尺寸稳定的硅酮水凝胶隐形眼镜。 透镜衍生自包含由式（1）表示的第一硅氧烷单体的可聚合组合物：其中式（1）的m表示3至10的一个整数，式（1）的n表示1至10的整数，R 1 式（1）的烷基是碳原子数为1〜4的烷基，式（1）的各R 2独立地为氢原子或甲基。 透镜还包括衍生自由式（2）表示的第二硅氧烷单体的单元：其中式（2）的R 1选自氢原子或甲基; 式（2）的R2选自氢原子或碳原子数为1〜4的烃基; 式（2）的m表示0〜10的整数， 式（2）的n表示4〜100的整数， a和b表示1以上的整数; a + b等于20-500; b /（a + b）等于0.01-0.22; 硅氧烷单元的构型包括随机构型，第二硅氧烷单体的数均分子量为至少3,000道尔顿，其存在于可聚合组合物中，其量使得第一硅氧烷单体与第二硅氧烷单体的比率在 至少2：1，单位重量份。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

公开(公告)号：US20130088488A1

公开(公告)日：2013-04-11

申请号：US13701907

申请日：2011-04-06

Applicant: Ye Hong

Inventor： Ye Hong

IPC: G06T15/20

CPC classification number: G06T15/205 ,  H04N13/122 ,  H04N13/144 ,  H04N13/327 ,  H04N13/332 ,  H04N13/366

Abstract: The invention discloses a method, apparatus and system for adjusting a stereoscopic image, a television set and stereoscopic glasses, wherein the method includes: receiving and displaying, by a display terminal, a three-dimensional stereoscopic image; transmitting, by a distance sensor, a sensing signal and obtaining a sighting distance between the display terminal and a user according to the sensing signal; and adjusting the size of the three-dimensional stereoscopic image according to the sighting distance. In the invention, stereoscopic geometrical distortion can be alleviated or even eliminated to thereby improve real experience feelings of watching the 3D stereoscopic display.

Abstract translation: 本发明公开了一种用于调整立体图像，电视机和立体眼镜的方法，装置和系统，其中所述方法包括：由显示终端接收和显示三维立体图像; 通过距离传感器传送感测信号，并根据感测信号获得显示终端与用户之间的瞄准距离; 以及根据瞄准距离调整三维立体图像的尺寸。 在本发明中，可以减轻或甚至消除立体几何失真，从而提高观看3D立体显示的真实感受。

公开(公告)号：US20120216489A1

公开(公告)日：2012-08-30

申请号：US13404041

申请日：2012-02-24

Applicant: Paul Hungchaung Lee ,  Ronghua Liu ,  Xinfeng Shi ,  Yuwen Liu ,  Ye Hong ,  Charlie Chen ,  Li Yao ,  Arthur Back ,  Charles A. Francis

Inventor： Paul Hungchaung Lee ,  Ronghua Liu ,  Xinfeng Shi ,  Yuwen Liu ,  Ye Hong ,  Charlie Chen ,  Li Yao ,  Arthur Back ,  Charles A. Francis

IPC: B65B63/00 ,  C08L43/04

CPC classification number: B29D11/00038 ,  G02B1/043 ,  C08L101/14 ,  C08L83/04 ,  C08L33/10

Abstract: Silicone hydrogel contact lenses that are derived from a polymerizable composition including at least one siloxane monomer and at least one hydrophilic monomer are described. These silicone hydrogel contact lenses have, when fully hydrated, has an equilibrium freezable water content of at least 25% wt/wt as determined by differential scanning calorimetry (DSC). Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract translation: 描述了衍生自包含至少一种硅氧烷单体和至少一种亲水单体的可聚合组合物的硅氧烷水凝胶隐形眼镜。 当通过差示扫描量热法（DSC）测定时，这些硅氧水凝胶隐形眼镜在完全水合时具有至少25％wt / wt的平衡可冷冻水含量。 还描述了硅胶水凝胶隐形眼镜的批次和制造硅酮水凝胶隐形眼镜的方法。

公开(公告)号：US20070248993A1

公开(公告)日：2007-10-25

申请号：US11761789

申请日：2007-06-12

Applicant: Michael Seul ,  Sukanta Banerjee ,  Kairali Podual ,  Ye Hong

Inventor： Michael Seul ,  Sukanta Banerjee ,  Kairali Podual ,  Ye Hong

IPC: C25D9/02 ,  C25D7/00 ,  G01N33/50

CPC classification number: C08J3/075 ,  C08J3/28 ,  C08J2333/26 ,  C08J2425/06 ,  C12Q1/6837 ,  G01N33/5005 ,  G01N33/545 ,  G03F7/0047 ,  G03F7/164 ,  Y10T428/249952 ,  Y10T428/25

Abstract: The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self supporting organic (polymeric) films and organic (polymeric)—microparticle composite films of tailored composition and morphology; the present invention further relates to the incorporation of said assemblies into other structures. The present invention also relates to the application of such functional assemblies in materials science and biology. Additional areas of application include sensors, catalysts, membranes, micro-reactors, smart materials. Miniaturized format for generation of multifunctional thin films. Provides a simple set-up to synthesize thin films of tailored composition and morphology:

Abstract translation: 本发明涉及一种用于产生功能组织的空间图案化聚合物 - 聚合物 - 微粒复合材料的系统方法，其包括图案化的自支撑有机（聚合物）膜和有机（聚合） - 微粒复合膜的交流电场介导组装 定制组合和形态; 本发明还涉及将所述组件结合到其它结构中。 本发明还涉及这种功能组件在材料科学和生物学中的应用。 其他应用领域包括传感器，催化剂，膜，微反应器，智能材料。 用于生成多功能薄膜的小型化格式。 提供简单的设置来合成定制组合和形态的薄膜：